Publications

February 15, 2022
Article

How Managers Can Build a Culture of Experimentation

By: Frank V. Cespedes and Neil Hoyne

Testing in business presents qualitatively different challenges than those in clinical trials and most scientific research. There are very few opportunities for randomized control experiments in a changing, competitive market. Yet, change and competition make testing a... View Details

Keywords: Experimentation; Management; Decision Making

June 2013
Article

Unconscious Thought Reduces Intrusion Development: A Replication and Extension

By: Julie Krans, Dorte Janecko and Maarten W. Bos

Background and Objectives: Intrusive images after a traumatic event, a hallmark feature of post-traumatic stress disorder, are suggested to develop because the trauma memory is disorganized and not integrated into autobiographical memory. Unconscious Thought... View Details

Keywords: Health Disorders; Cognition and Thinking

November 2009 (Revised August 2010)
Case

NovoCure Ltd.

By: William A. Sahlman and Sarah Flaherty

Venture capitalist William Doyle must raise $35 million for a portfolio company with a promising, novel cancer therapy, just as global capital markets are imploding in the fall of 2008. NovoCure, Ltd., has developed an electrical-field-based therapy, called Tumor... View Details

Keywords: Financial Crisis; Entrepreneurship; Venture Capital; Investment; Health Care and Treatment; Health Testing and Trials; Technological Innovation; Financial Services Industry

Educators

February 2022 (Revised April 2022)
Case

CVS Health: Prescription for Transformation

By: Rosabeth Moss Kanter and Tuna Cem Hayirli

In 2021, new CEO Karen Lynch (named the most powerful woman in business) considered the next transformation phase for CVS Health (a Fortune 5 corporate giant. The 2018 acquisition of Aetna insurance brought her to the company as part of its long evolution from a... View Details

Keywords: COVID; Caregiving; Healthcare; Access; Change; Retail; Health; Health Care and Treatment; Organizational Change and Adaptation; Transformation; Health Industry; Health Industry

Educators

May 16, 2016
Article

Food Safety Economics: The Cost of a Sick Customer

By: Dina Gerdeman and John A. Quelch

Chipotle Mexican Grill’s ongoing struggle to win customers back months after a contaminated food crisis highlights the challenges companies face with keeping food safe.

Chipotle has seen its shares tumble and recently reported its first-ever quarterly loss... View Details

04 Sep 2018
First Look

New Research and Ideas, September 4, 2018

W. Feeley Abstract—Patients and providers are frustrated with seemingly endless data entry. We used our patients’ vested interest in their own health care by actively engaging them in the entry of their own... View Details

Keywords: Dina Gerdeman

24 Jul 2018
First Look

New Research and Ideas, July 24, 2018

to change your life. Publisher's link: https://www.hbs.edu/faculty/Pages/item.aspx?num=54720 in press Health Care Management Review Innovation Contest: Effect of Perceived Support for Learning on Participation By: Jung, Olivia S., Andrea... View Details

Keywords: Dina Gerdeman

02 Jun 2020
Research & Ideas

Coronavirus Careers: Cloud Kitchens Are Now Serving

kitchens can test new restaurant concepts, menu items, and seasonal brands (for example, a salad brand in the summer) more easily without costly investments. It is still an emergent business model with lots... View Details

Keywords: by Lena Ye and Geoffrey Jones; Food & Beverage

Article

Decisions about Medication Use and Cancer Screening across Age Groups in the United States

By: Kathleen M. Fairfield, Bethany S. Gerstein, Carrie A. Levin, Vickie Stringfellow, Heidi Wierman and Mary McNaughton-Collins

Objective
To describe decision process and quality for common cancer screening and medication decisions by age group.

Methods
We included 2941 respondents to a national Internet survey who made at least one decision about colorectal, breast,... View Details

Keywords: Screening; Decision Making; Health Care and Treatment; Health Testing and Trials

December 2020
Article

What Has Changed? The Impact of COVID Pandemic on the Technology and Innovation Management Research Agenda

By: Gerard George, Karim R. Lakhani and Phanish Puranam

Whereas the pandemic has tested the agility and resilience of organizations, it forces a deeper look at the assumptions underlying theoretical frameworks that guide managerial decisions and organizational practices. In this commentary, we explore the impact of the... View Details

Keywords: COVID-19; Health Pandemics; Information Technology; Innovation and Management; Research

2017
Article

Blunted Ambiguity Aversion During Cost-Benefit Decisions in Antisocial Individuals

By: Joshua W. Buckholtz, Uma R. Karmarkar, Shengxuan Ye, Grace M. Brennan and Arielle Baskin-Sommers

Antisocial behavior is often assumed to reflect aberrant risk processing. However, many of the most significant forms of antisocial behavior, including crime, reflect the outcomes of decisions made under conditions of ambiguity rather than risk. While risk and... View Details

Keywords: Ambiguity; Neuroscience; Neuroeconomics; Choice; Psychology; Decision Choice And Uncertainty; Behavior; Decision Choices and Conditions; Cost vs Benefits; Health Disorders

27 Jun 2017
First Look

First Look at New Research and Ideas, June 27

and elsewhere. Yet the book shows that these entrepreneurs contributed significantly to the growth of environmental awareness among consumers, business leaders, and others. However the Earth's environmental... View Details

Keywords: Sean Silverthorne

January–February 2023
Article

Data-Driven COVID-19 Vaccine Development for Janssen

By: Dimitris Bertsimas, Michael Lingzhi Li, Xinggang Liu, Jennings Xu and Najat Khan

The COVID-19 pandemic has spurred extensive vaccine research worldwide. One crucial part of vaccine development is the phase III clinical trial that assesses the vaccine for safety and efficacy in the prevention of COVID-19. In this work, we enumerate the first... View Details

Keywords: COVID-19; Health Testing and Trials; Forecasting and Prediction; AI and Machine Learning; Research; Pharmaceutical Industry

September 2020 (Revised September 2021)
Supplement

Student Success at Georgia State University (B)

By: Michael W. Toffel, Robin Mendelson and Julia Kelley

This is a supplement to the Student Success at Georgia State University (A) case. The (B) case includes the results of a randomized control trial that Georgia State conducted to test education technology start-up AdmitHub’s chatbot solution as a strategy for improving... View Details

24 Feb 2020
Research & Ideas

The Hidden Vulnerabilities of Open Source Software

is difficult to fully understand the health and security of FOSS because 1) by design, it is distributed in nature so there is no central authority to ensure quality and... View Details

Keywords: by Frank Nagle and Jenny Hoffman; Computer

2018
Chapter

The Orphan Drug Act at 35: Observations and an Outlook for the Twenty-First Century

By: Nicholas Bagley, Benjamin Berger, Amitabh Chandra, Craig Garthwaite and Ariel Dora Stern

On the 35th anniversary of the adoption of the Orphan Drug Act (ODA), we describe the enormous changes in the markets for therapies for rare diseases that have emerged over recent decades. The most prominent example is the fact that the profit-maximizing price of new... View Details

Keywords: Health Care and Treatment; Laws and Statutes; Research and Development; Investment; Markets; Monopoly

Register to Read

Article

The Impact of Intangibles on Firm Growth

By: Stefano Denicolai, E. Cotta Ramusino and F. Sotti

Persuading users to try new technologies continues to be a problem confronting organisations and technology vendors alike. To better understand the process of new technology trial and adoption, several theoretical models have been proposed, of which the Technology... View Details

Keywords: Motivation and Incentives; Technology Adoption

03 Oct 2023
Research Event

Build the Life You Want: Arthur Brooks and Oprah Winfrey Share Happiness Tips

community too. Like I'm a Harvard professor and I'm darn proud of it. Will this represent you in a way that you'll say, that was a good thing that we did as a community for this world. Will we bring Harvard University to the world View Details

Keywords: by HBS Staff

2023
Working Paper

Market Exclusivity and Innovation: Evidence From Antibiotics

By: Edward Kong and Olivia Zhao

The US incentivizes drug innovation via patents as well as market exclusivity periods awarded by the US Food and Drug Administration. We estimate the causal effects of extending market exclusivity for an important drug class: antibiotics. Using a... View Details

Keywords: Health Testing and Trials; Innovation and Invention; Motivation and Incentives; Government Administration; Government Legislation; Pharmaceutical Industry; United States