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September 2022
Article

Trends in Remote Patient Monitoring Use in Traditional Medicare

By: Mitchell Tang, Carter Nakamoto, Ariel Dora Stern and Ateev Mehrotra

Remote patient monitoring (RPM), the collection by patients of physiological measurements that are automatically sent to their health care practitioners, has been touted as a promising tool for improving chronic disease management. Interest in RPM has grown because of... View Details

Keywords: Medicare; Remote Monitoring; Reimbursement; Health Care and Treatment; Health Industry

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July 2024
Case

Gates Ventures: Making Alzheimer's a Forgotten Past

By: Satish Tadikonda, William Marks, Shardule Shah and Calvin Marambo

After a personal journey and interest in Alzheimer's Disease (AD) by Bill Gates, Gates Ventures set out to find the best way to accelerate innovation in the field of AD. In partnership with the Alzheimer's Drug Discovery Foundation, Gates Ventures created the... View Details

Keywords: Philanthropy and Charitable Giving; Entrepreneurial Finance; Health Disorders; Mission and Purpose

Research Summary

Overview

My research seeks to understand and improve service integration across specialized professions and organizations. A critical idea driving my research is that work is becoming more dynamic, complex and interconnected, particularly for work that addresses difficult... View Details

Keywords: Organization Behavior; Health Care Delivery; Team Effectiveness; Organizational Learning

March 2010 (Revised October 2011)
Case

Highland District County Hospital: Gastroenterology Care in Sweden

By: Michael E. Porter, Jennifer F Baron and Martin Rejler

Sweden's Highland District County Hospital, similar to a community hospital in the US, undertook a major restructuring to integrate care delivery for medical conditions served by the Department of Medicine. Each subspecialty within the Department would form a single,... View Details

Keywords: Health Care and Treatment; Sweden

2023
Article

Building the Business Case for an Inclusive Approach to Digital Health Measurement with a Web App (Market Opportunity Calculator): Instrument Development Study

By: Mitchell Tang, Yashoda Sharma, Jennifer C. Goldsack and Ariel Dora Stern

Background: The use of digital health measurement tools has grown substantially in recent years. However, there are concerns that the promised benefits from these products will not be shared equitably. Underserved populations, such as those with lower education and... View Details

Keywords: Demographics; Product Development; Health Care and Treatment; Medical Devices and Supplies Industry

February 2020 (Revised January 2024)
Case

Wellthy: The Economics of Caring

By: Brian L. Trelstad and Joseph B. Fuller

In 2014, Lindsay Jurist-Rosner (MBA ’09) founded Wellthy, a B2C business that coordinates care for working professionals seeking help to support loved ones with chronic diseases or aging parents. With personal experience as a young professional providing care for her... View Details

Keywords: B2B Vs. B2C; Future Of Work; Health; Social Entrepreneurship; Growth and Development Strategy; Health Industry; United States

January 2023
Supplement

Apple: Privacy vs. Safety (B)

By: Henry McGee, Nien-hê Hsieh and Christian Godwin

In 2020, as the COVID-19 pandemic swept across the globe, Apple and Google partnered to develop a contact tracing application that would collect information about users infected with the disease and notify those who they had been in contact with. While Apple/Google’s... View Details

December 2009
Article

From a Declaration of Values to the Creation of Value in Global Health

By: Jim Yong Kim, Joseph Rhatigan, Sachin H. Jain and Michael E. Porter

To make best use of the new dollars available for the treatment of disease in resource poor settings, global health practice requires a strategic approach that emphasizes value for patients, defined as health outcomes per dollar spent. Practitioners and global health... View Details

Keywords: Globalization; Health Care and Treatment; Infrastructure; Service Delivery; Outcome or Result; Poverty; Value Creation

November 2005 (Revised December 2005)
Case

County Department of Public Health: Organizing for Emergency Preparedness and Response

By: Lynda M. Applegate, Ajay Vinze and Minu Ipe

The anthrax attacks of 2001 exposed serious inadequacies in the response of the U.S. public health system to meet such grave threats. The public health infrastructure required rebuilding to respond to any type of large-scale health emergency. The Public Health... View Details

Keywords: Information Technology; Change Management; Crisis Management; Health Care and Treatment; Infrastructure; Public Administration Industry; Health Industry; United States

September 2002 (Revised August 2003)
Case

Genzyme's Gaucher Initiative: Global Risk and Responsibility

By: Christopher A. Bartlett and Andrew N. McLean

In Egypt, Genzyme's humanitarian commitment to treat all sufferers of the rare Gaucher disease worldwide first confronts its commercial imperative to recoup the huge investment required to bring the drug Cerezyme to market. Here Tomye Tierney must decide how to balance... View Details

Keywords: Moral Sensibility; Investment; Emerging Markets; Negotiation; Corporate Social Responsibility and Impact; Business and Government Relations; Sales; Commercialization; Expansion; Value Creation

Managing Growth

But marketing was important. Even if we produced the greatest drugs in the world, we’d be in trouble if we couldn’t get doctors to prescribe them or insurers to pay for them. As for our reluctance to look outside the company for ideas, I like to say that 0.1% of the... View Details

February 2009
Case

Avid Radiopharmaceuticals: The Venture Debt Question

By: Matthew Rhodes-Kropf and Ann Leamon

The CEO of a promising biotech company must decide how to respond to the macro-economic slump of late 2008. He had planned to pursue an aggressive schedule, moving the firm's Alzheimer's and Parkinson's disease imaging compounds through clinical trials and into the... View Details

Keywords: Financial Crisis; Entrepreneurship; Borrowing and Debt; Venture Capital; Financial Management; Investment; Health Testing and Trials; Expansion; Biotechnology Industry; Pharmaceutical Industry

September–October 2020
Article

The Past, Present, and (Near) Future of Gene Therapy and Gene Editing

By: Julia Pian, Amitabh Chandra and Ariel Dora Stern

Emerging gene therapy and gene-editing technologies will have a growing impact on patient lives and health-care delivery. We analyzed a decade of data on clinical trials and venture capital investments to understand the likely trajectory of genetically focused... View Details

Keywords: Gene Therapy; Gene Editing; Impact; Health Care and Treatment; Technological Innovation; Health Testing and Trials; Venture Capital; Change

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July 2019
Article

The Impact of Price Regulation on the Availability of New Drugs in Germany

By: Ariel Dora Stern, Felicitas Pietrulla, Annika Herr, Aaron S. Kesselheim and Ameet Sarpatwari

The 2011 German Pharmaceutical Market Restructuring Act (“AMNOG”) subjected branded, non-rare disease drugs to price regulation based on an assessment of their clinical benefit. Assessment outcomes range from “major added benefit” to “less benefit than the appropriate... View Details

Keywords: Regulation; Pharmaceuticals; Healthcare; Health Care and Treatment; Price; Governing Rules, Regulations, and Reforms; Pharmaceutical Industry; Germany

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2022
Working Paper

TalkToModel: Explaining Machine Learning Models with Interactive Natural Language Conversations

By: Dylan Slack, Satyapriya Krishna, Himabindu Lakkaraju and Sameer Singh

Practitioners increasingly use machine learning (ML) models, yet they have become more complex and harder to understand. To address this issue, researchers have proposed techniques to explain model predictions. However, practitioners struggle to use explainability... View Details

Keywords: Natural Language Conversations; Predictive Models; AI and Machine Learning

August 2018
Article

The Effect of Graphic Warnings on Sugary-Drink Purchasing

By: Grant Donnelly, Laura Y. Zatz, Daniel Svirsky and Leslie John

Governments have proposed text warning labels to decrease consumption of sugary drinks – a contributor to chronic diseases like diabetes. However, they may be less effective than more evocative, graphic warning labels. We field-tested the effectiveness of graphic... View Details

Keywords: Policy Making; Preferences; Food; Health; Policy; Information; Labels; Consumer Behavior; Decision Making; Performance Effectiveness

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December 2012 (Revised November 2014)
Case

W.R. Grace & Co.: Dealing with Asbestos Torts

By: Stuart C. Gilson and Sarah L. Abbott

A manufacturer of building products and specialty chemicals, W. R. Grace & Co. filed for Chapter 11 bankruptcy in 2001 in response to a flood of lawsuits alleging that its products contained asbestos, and had caused hundreds of thousands of people to contract... View Details

Keywords: Bankruptcy Reorganization; Business Failures; Environmental Regulations; Class Action Lawsuits; Natural Environment; Valuation; Health Disorders; Capital Structure; Restructuring; Lawsuits and Litigation; Chemicals; Crisis Management; Insolvency and Bankruptcy; Legal Liability; Construction Industry; Chemical Industry; United States

28 Apr 2011
News

Harvard Business School Holds 15th Annual Business Plan Contest

July 2022
Teaching Plan

Wellthy: The Economics of Caring

By: Brian Trelstad

Teaching Plan for HBS Case No. 320-028. In 2014, Lindsay Jurist-Rosner (MBA ’09) founded Wellthy, a B2C business that coordinates care for working professionals seeking help to support loved ones with chronic diseases or aging parents. With personal experience as a... View Details

Keywords: B2B Vs. B2C; Future Of Work; Health; Social Entrepreneurship; Growth and Development Strategy; Health Care and Treatment; Recruitment; Corporate Social Responsibility and Impact; Health Industry; United States

01 May 2020
News

The Business of Medicine in the Era of COVID-19

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