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    • Research  (699)
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  • Research Summary

The Institutional Foundations of Lending: Indirect Regulation and State-Building

The Institutional Foundations of Lending: Indirect Regulation and State-Building makes two main theoretical contributions to the scholarship on credit markets and institutional development. First, the book demonstrates that opportunistic lenders can take... View Details
  • January 2017
  • Article

Impact Evaluation Methods in Public Economics: A Brief Introduction to Randomized Evaluations and Comparison with Other Methods

By: Dina Pomeranz
Recent years have seen a large expansion in the use of rigorous impact evaluation techniques. Increasingly, public administrations are collaborating with academic economists and other quantitative social scientists to apply such rigorous methods to the study of public... View Details
Keywords: Practice; Public Sector; Research; Policy; Performance Evaluation
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Pomeranz, Dina. "Impact Evaluation Methods in Public Economics: A Brief Introduction to Randomized Evaluations and Comparison with Other Methods." Special Issue on Expanding the Frontier of Behavioral Public Economics. Public Finance Review 45, no. 1 (January 2017): 10–43. (Published early online November 5, 2015. Spanish version available by clicking on "Details.")
  • October 2021 (Revised January 2022)
  • Supplement

Michael Ku and Global Clinical Supply at Pfizer Inc.: Bringing Hope to Patients (C)

By: Linda A. Hill and Emily Tedards
This case is the third installment in a series about the 10-year cultural and digital transformation of Pfizer’s Global Clinical Supply organization. In 2011, Michael Ku became Pfizer’s Vice President of Global Clinical Supply (GCS) after the company had undergone... View Details
Keywords: Clinical Supply Chain; COVID-19; Vaccine; Agile; Innovation and Invention; Change Management; Organizational Culture; Transformation; Leadership; Corporate Strategy; Health Pandemics; Crisis Management; Mission and Purpose; Health Care and Treatment; Supply Chain Management; Digital Transformation
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Hill, Linda A., and Emily Tedards. "Michael Ku and Global Clinical Supply at Pfizer Inc.: Bringing Hope to Patients (C)." Harvard Business School Supplement 422-041, October 2021. (Revised January 2022.)
  • 22 Apr 2015
  • Op-Ed

Reforming Greece: Myths and Truths

rights. Protection of property rights in the country is still poor and a major deterrent to investment. Greece scores just a 3 out of 12 on a World Bank's strength-of-legal-rights index, actually decreasing from 4 in 2007. Tellingly, the... View Details
Keywords: by George Serafeim
  • 14 Nov 2017
  • First Look

New Research and Ideas: November 14, 2017

experts to discuss how researchers can impact a broader audience, by lending their scientific expertise to pressing social issues, current events, and public debates. The landmark Brown v. Board of Education case, in which the Supreme... View Details
Keywords: Carmen Nobel
  • March 2019
  • Case

DayTwo: Going to Market with Gut Microbiome

By: Ayelet Israeli and David Lane
DayTwo is a young Israeli startup that applies research on the gut microbiome and machine learning algorithms to deliver personalized nutritional recommendations to its users in order to minimize blood sugar spikes after meals. After a first year of trial rollout in... View Details
Keywords: Start-up Growth; Startup; Positioning; Targeting; Go To Market Strategy; B2B2C; B2B Vs. B2C; Health & Wellness; AI; Machine Learning; Female Ceo; Female Protagonist; Science-based; Science And Technology Studies; Ecommerce; Applications; DTC; Direct To Consumer Marketing; US Health Care; "USA,"; Innovation; Pricing; Business Growth; Segmentation; Distribution Channels; Growth and Development Strategy; Business Startups; Science-Based Business; Health; Innovation and Invention; Marketing; Information Technology; Business Growth and Maturation; E-commerce; Applications and Software; Food and Beverage Industry; Food and Beverage Industry; Food and Beverage Industry; Food and Beverage Industry; Food and Beverage Industry; Israel; United States
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Israeli, Ayelet, and David Lane. "DayTwo: Going to Market with Gut Microbiome." Harvard Business School Case 519-010, March 2019.
  • December 2002
  • Teaching Note

Abgenix and the XenoMouse (TN)

By: John T. Gourville
Teaching Note for (501-061). View Details
Keywords: Health Testing and Trials; Decision Choices and Conditions; Sales; Product Development; Joint Ventures; Health Industry; Pharmaceutical Industry
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Gourville, John T. "Abgenix and the XenoMouse (TN)." Harvard Business School Teaching Note 503-046, December 2002.
  • 2018
  • Chapter

The Orphan Drug Act at 35: Observations and an Outlook for the Twenty-First Century

By: Nicholas Bagley, Benjamin Berger, Amitabh Chandra, Craig Garthwaite and Ariel Dora Stern
On the 35th anniversary of the adoption of the Orphan Drug Act (ODA), we describe the enormous changes in the markets for therapies for rare diseases that have emerged over recent decades. The most prominent example is the fact that the profit-maximizing price of new... View Details
Keywords: Health Care and Treatment; Laws and Statutes; Research and Development; Investment; Markets; Monopoly
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Bagley, Nicholas, Benjamin Berger, Amitabh Chandra, Craig Garthwaite, and Ariel Dora Stern. "The Orphan Drug Act at 35: Observations and an Outlook for the Twenty-First Century." Chap. 4 in Innovation Policy and the Economy, Volume 19, edited by Josh Lerner and Scott Stern, 97–137. University of Chicago Press, 2018.
  • Summer 2015
  • Article

The Effect of Delaware Doctrine on Freezeout Structure and Outcomes: Evidence on the Unified Approach

By: Fernan Restrepo and Guhan Subramanian
Historically, Delaware corporate law provided different standards of judicial review for buyouts by controlling shareholders (also known as "freezeouts") based on what transactional form was used: deferential business judgment review for freezeouts executed as tender... View Details
Keywords: Laws and Statutes; Business and Shareholder Relations; Delaware
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Restrepo, Fernan, and Guhan Subramanian. "The Effect of Delaware Doctrine on Freezeout Structure and Outcomes: Evidence on the Unified Approach." Harvard Business Law Review 5, no. 2 (Summer 2015): 205–236.
  • 12 Jun 2018
  • First Look

New Research and Ideas, June 12, 2018

forthcoming Cambridge, MA: Harvard University Press The Academy of Fisticuffs: Political Economy and Commercial Society in Enlightenment Italy By: Reinert, Sophus A. Abstract—The terms “capitalism” and... View Details
Keywords: Dina Gerdeman
  • Forthcoming
  • Article

Sending a Message: An Empirical Assessment of Responses to Punitive and Non-punitive Compliance Messaging Strategies

By: Jodi L. Short, Michael W. Toffel, Elizabeth A. Keenan and Melissa Ouellet
Regulators operate in an increasingly hostile political environment. The U.S. Supreme Court is ramping up efforts to curtail the authority of administrative agencies. The second election of Donald Trump to the presidency has unleashed a torrent of anti-regulatory... View Details
Keywords: Field Experiment; Compliance; Compliance Programs; Compliance Policies; Regulatory Enforcement; Environmental Regulation; Environmental Policy; Government Experimentation; Governance Compliance; Government Administration; Governing Rules, Regulations, and Reforms; Business and Government Relations; Construction Industry; Public Administration Industry; California; United States
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Short, Jodi L., Michael W. Toffel, Elizabeth A. Keenan, and Melissa Ouellet. "Sending a Message: An Empirical Assessment of Responses to Punitive and Non-punitive Compliance Messaging Strategies." Ecology Law Quarterly (forthcoming).
  • 10 Jul 2018
  • First Look

New Research and Ideas, July 10, 2018

business plans, and key personnel ignited a bi-coastal battle between two fierce rivals that was played out in courts competing for jurisdiction and states with diametrically... View Details
Keywords: Dina Gerdeman
  • 25 Jul 2023
  • Research & Ideas

Could a Business Model Help Big Pharma Save Lives and Profit?

Might Also Like: The FDA’s Speedy Drug Approvals Are Safe: A Win-Win for Patients and Pharma Innovation Curbing an Unlikely Culprit of Rising Drug Prices: Pharmaceutical Donations Buy-In from Black Patients Suffers When Drug View Details
Keywords: by Esther Schrader; Pharmaceutical; Health
  • 2024
  • Working Paper

Do Information Frictions and Corruption Perceptions Kill Competition? A Field Experiment on Public Procurement in Uganda

By: Emanuele Colonnelli, Francesco Loiacono, Edwin Muhumuza and Edoardo Teso
We study whether information frictions and corruption perceptions deter firms from doing business with the government. We conduct two nationwide randomized controlled trials (RCTs) in collaboration with the national public procurement supervisory and anti-corruption... View Details
Keywords: Knowledge Use and Leverage; Government and Politics; Crime and Corruption; Trust; Perception; Business and Government Relations
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Colonnelli, Emanuele, Francesco Loiacono, Edwin Muhumuza, and Edoardo Teso. "Do Information Frictions and Corruption Perceptions Kill Competition? A Field Experiment on Public Procurement in Uganda." NBER Working Paper Series, No. 32170, February 2024.
  • March 1991 (Revised July 2001)
  • Supplement

Ann Hopkins (B)

By: Joseph L. Badaracco Jr. and Ilyse Barkan
Describes the reasons why the courts found in favor of Ann Hopkins in the sexual discrimination suit. Also explains why the courts concluded she was the victim of sexual stereotyping. View Details
Keywords: Law; Ethics; Human Resources; Gender
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Badaracco, Joseph L., Jr., and Ilyse Barkan. "Ann Hopkins (B)." Harvard Business School Supplement 391-170, March 1991. (Revised July 2001.)
  • 08 Mar 2019
  • Research & Ideas

Seven Negotiation Lessons from Amazon's HQ Disaster in Queens

negotiating too narrowly with those who have formal power and authority. Negotiation experts have a patriarchal name for a version of this classic—and avoidable—mistake: Decide-Announce-Defend or DAD. Along with gaining the full-throated... View Details
Keywords: by James K. Sebenius; Real Estate; Construction
  • September 1984 (Revised July 2005)
  • Case

Higgins v. Commissioner

By: Henry B. Reiling
Discusses the issue of whether an activity is a trade or business. The Court held that the taxpayer's very substantial stock and bond portfolio management activities were not a trade or business, whereas the taxpayer's real estate activities did constitute a trade or... View Details
Keywords: Taxation; Courts and Trials; Investment Portfolio; Property; United States
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Reiling, Henry B. "Higgins v. Commissioner." Harvard Business School Case 285-008, September 1984. (Revised July 2005.)
  • 2023
  • Working Paper

Life After Death: A Field Experiment with Small Businesses on Information Frictions, Stigma, and Bankruptcy

By: Shai Benjamin Bernstein, Emanuele Colonnelli, Mitchell Hoffman and Benjamin Iverson
In a randomized control trial (RCT) with U.S. small businesses, we document that a large share of firms are not well-informed about bankruptcy. Many assume that bankruptcy necessarily entails the death of a business and do not know about Chapter 11 bankruptcy, where... View Details
Keywords: Small Business; Insolvency and Bankruptcy; Knowledge Dissemination; Outcome or Result
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Bernstein, Shai Benjamin, Emanuele Colonnelli, Mitchell Hoffman, and Benjamin Iverson. "Life After Death: A Field Experiment with Small Businesses on Information Frictions, Stigma, and Bankruptcy." NBER Working Paper Series, No. 30933, February 2023.
  • 18 Dec 2018
  • First Look

New Research and Ideas, December 18, 2018

firms face little competition, even after the end of formal periods of patent protection and market exclusivity. Additionally, the evolving technologies of drug development—in particular, the increasingly common use of auxiliary endpoints... View Details
Keywords: Dina Gerdeman
  • 08 Dec 2003
  • Research & Ideas

Why Europe Lags in Pharmaceuticals and Biotech

the preferred testing ground for Phase 1 clinical trials of new drugs, the benefits of massive R&D spending and economic throw-offs are being enjoyed elsewhere, primarily in the United States View Details
Keywords: by Sean Silverthorne; Biotechnology; Health; Pharmaceutical; Technology
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