Publications

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May 2021
Case

The SMA Foundation: Steering Therapeutic Research and Development in a Rare Disease

By: Amitabh Chandra, Spencer Lee-Rey and Caroline Marra

This case explores incentives for rare disease drug development by chronicling the role of the Spinal Muscular Atrophy (SMA) Foundation in forming strategic partnerships with the scientific research community and pharmaceutical developers to transform the trajectory... View Details

Keywords: Innovation and Invention; Strategy; Business or Company Management; Society; Health; Public Administration Industry; Health Industry; United States

September 2014 (Revised March 2016)
Case

Mayo Clinic: The 2020 Initiative

By: Regina E. Herzlinger, Robert S. Huckman and Jenny Lesser

Describes the challenges facing Dr. John Noseworthy, President and CEO, in implementing a long-term strategy for the growth of the Mayo Clinic—a leading academic medical center with a reputation for excellence in tertiary and quaternary health care. The case highlights... View Details

Keywords: Health; Health Care Industry; Health Care Policy; Health Care and Treatment; Health Industry; United States

November 2019 (Revised December 2019)
Case

Martini Klinik: Prostate Cancer Care 2019

By: Michael E. Porter, Jens Deerberg-Wittram and Thomas W. Feeley

Since its establishment in 2005, Hamburg’s Martini Klinik had single mindedly focused on prostate cancer care with a commitment to measure long-term health outcomes for every patient. A wholly owned subsidiary of the University Hospital Hamburg, Martini Klinik was a... View Details

01 Apr 2013
News

Rx: Human Nature

23 Jan 2018
Video

Dr. Marlene Krauss: Health Care Visionary

January 2024
Article

A Cost Model for a Low Threshold Clinic Treating Opioid Use Disorder

By: Sarah E. Wakeman, Elizabeth Powell, Syed Shehab, Grace Herman, Laura Kehoe and Robert S. Kaplan

The US fee-for-service payment system under-reimburses clinics offering access to comprehensive treatments for opioid use disorder (OUD). The funding shortfall limits a clinic’s ability to expand and improve access, especially for socially marginalized patients with... View Details

Keywords: Health Care and Treatment; Cost; Equality and Inequality; Health Industry

Find at Harvard

14 Nov 2017
First Look

New Research and Ideas: November 14, 2017

through three examples: the design of medical residency matching programs, a scrip system to allocate food donations to food banks, and the recent "Incentive Auction" that reallocated wireless spectrum from television broadcasters to... View Details

Keywords: Carmen Nobel

October 19, 2015
Article

Getting Bundled Payments Right in Health Care

By: Robert S. Kaplan, Derek A. Haas, Dereesa Reid, Jonathan Warsh and Michael E. West

Bundled payments—single payments that cover all the care for a patient’s medical condition or treatment over a specified timeframe—are increasingly being deployed to motivate the delivery of better patient outcomes at lower costs. Hoag Orthopedic Institute (HOI), a... View Details

Keywords: Health Care and Treatment; Product Marketing; Health Industry

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October 2009 (Revised August 2014)
Case

Tengion: Bringing Regenerative Medicine to Life

By: Elie Ofek and Polly Ross Ribatt

Tengion is a young biotech company that is at the frontier of regenerative medicine—a nascent field that seeks to promote the creation of new cells and tissue to repair or replace tissue or organ function lost due to age, disease, damage, or congenital defects. In late... View Details

Keywords: Decision Choices and Conditions; Financial Crisis; Entrepreneurship; Health Care and Treatment; Technological Innovation; Product Launch; Product Development; Research and Development; Biotechnology Industry; United States

April 2009 (Revised November 2012)
Case

Sermo, Inc.

By: Thomas R. Eisenmann and Lars Peter Christian Nielsen

Sermo operates the leading online professional network for physicians in the United States. Doctors use Sermo free of charge to post surveys regarding diagnostic and treatment concerns and to discuss these concerns, as well as challenges with managing their practices.... View Details

Keywords: Entrepreneurship; Health Care and Treatment; Knowledge Sharing; Two-Sided Platforms; Conflict and Resolution; Social and Collaborative Networks; United States

2020
Working Paper

Mission-Oriented Research in a National Emergency: Lessons from the Office of Scientific Research and Development in World War II

By: Daniel P. Gross and Bhaven N. Sampat

Since the beginning of the present COVID-19 pandemic, policymakers, researchers, and journalists have made repeated comparisons to World War II. In ongoing research, we have been studying the effects of the World War II research effort, which included a major medical... View Details

Keywords: Innovation and Invention; Research and Development; Problems and Challenges; War; History; Government Administration; United States

22 Jun 2020
News

On Track: Health Care, Patient Data, and Provider Performance

29 Jun 2013
News

Hospital operators and Obamacare: Prescription for change

April 2017
Supplement

Imprimis (B)

By: Ramon Casadesus-Masanell, Karen Elterman and Marc Appel

This case is a supplement to Imprimis (A). It describes the company’s decision to enter into the pharmaceutical compounding business in 2013–2014. Imprimis purchased a compounded ophthalmological medication called Dropless Therapy, which was injected into patients’... View Details

Keywords: Healthcare; Drug Compounding; Drug Development; Pharmaceuticals; Small Business; Decision-making, Business Model; Mark Baum; Imprimis; Decision Making; Strategy; Health Care and Treatment; Policy; Pharmaceutical Industry; United States

15 Jul 2013
Research & Ideas

Five Imperatives for Improving Health Care

Innovation in health care treatment seems to far outpace innovation in health care business management. Just ask President Obama—two weeks ago he delayed enactment of a key provision of the new health care law for fear its requirements... View Details

Keywords: by Carmen Nobel; Health

April 2012 (Revised February 2013)
Case

Learning About Reducing Hospital Mortality at Kaiser Permanente

By: Anita Tucker

In 2011, Kaiser Permanente Northern California (KPNC) region's efforts to reduce mortality in their 21 hospitals is showing promise. They developed and launched a region-wide initiative to improve the treatment of sepsis, a serious and often deadly medical condition.... View Details

Keywords: Change Management; Health Care and Treatment; Performance Improvement; Health Industry; California

May 2023 (Revised June 2023)
Case

Novartis (A): Reimagining Medicine

By: Ramon Casadesus-Masanell, Claudio Feser, Karolin Frankenberger and David Redaschi

This case unfolds around the first-ever approved personalized cancer treatment, how Novartis wrapped it into a new business model design, and how Novartis scaled it. Novartis — one of the largest pharmaceutical companies in the world — is, among other ventures,... View Details

Keywords: Health Care and Treatment; Business Model; Leadership; Pharmaceutical Industry; Switzerland