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      • December 2014 (Revised August 2015)
      • Case

      Improving Melanoma Screening: MELA Sciences

      By: Regina E. Herzlinger, Kevin Schulman and Frédéric Dijols
      MELA is a start-up medical device company looking to develop a novel technology to help physicians diagnose a deadly skin cancer, melanoma. The case reviews the FDA medical device development process, the development path pursued by MELA, and the regulatory and... View Details
      Keywords: Healthcare Industry; Health Care; Health; Health Care and Treatment; Health Testing and Trials; Health Industry; United States
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      Herzlinger, Regina E., Kevin Schulman, and Frédéric Dijols. "Improving Melanoma Screening: MELA Sciences." Harvard Business School Case 315-042, December 2014. (Revised August 2015.)
      • November 2014 (Revised March 2016)
      • Background Note

      Mental Health and the American Workplace

      By: John A. Quelch and Carin-Isabel Knoop
      Mental illness has been described as an epidemic affecting nearly a quarter of all Americans in their lifetimes, often during their most productive working years. Managers who can design organizations that maximize mental health can minimize these risks and boost... View Details
      Keywords: Public Health; Productivity; Competitiveness; Stress Management; Depression; Absenteeism; Presenteeism; Work Culture; Business or Company Management; Work-Life Balance; Performance Productivity; Organizational Culture; Medical Specialties; Health Care and Treatment; Health Industry; United States
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      Quelch, John A., and Carin-Isabel Knoop. "Mental Health and the American Workplace." Harvard Business School Background Note 515-062, November 2014. (Revised March 2016.)
      • September 2014 (Revised March 2016)
      • Case

      Mayo Clinic: The 2020 Initiative

      By: Regina E. Herzlinger, Robert S. Huckman and Jenny Lesser
      Describes the challenges facing Dr. John Noseworthy, President and CEO, in implementing a long-term strategy for the growth of the Mayo Clinic—a leading academic medical center with a reputation for excellence in tertiary and quaternary health care. The case highlights... View Details
      Keywords: Health; Health Care Industry; Health Care Policy; Health Care and Treatment; Health Industry; United States
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      Herzlinger, Regina E., Robert S. Huckman, and Jenny Lesser. "Mayo Clinic: The 2020 Initiative." Harvard Business School Case 615-027, September 2014. (Revised March 2016.)
      • July 2014
      • Case

      BMVSS: Changing Lives through Innovation One Jaipur Limb at a Time (Abridged)

      By: Srikant Datar, Saloni Chaturvedi and Caitlin Bowler
      Bhagwan Mahaveer Viklang Sahayata Samiti (BMVSS) is an Indian not-for-profit organization engaged in assisting differently-abled persons by providing them with the legendary low-cost prosthesis, the Jaipur Foot, and other mobility-assisting devices, free of cost. Known... View Details
      Keywords: Nonprofit Organizations; Financial Condition; Health Care and Treatment; Diversity; Growth and Development Strategy; Philanthropy and Charitable Giving; Medical Devices and Supplies Industry; Medical Devices and Supplies Industry; India
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      Datar, Srikant, Saloni Chaturvedi, and Caitlin Bowler. "BMVSS: Changing Lives through Innovation One Jaipur Limb at a Time (Abridged)." Harvard Business School Case 115-009, July 2014.
      • July 2014 (Revised January 2017)
      • Course Overview Note

      Building Life Science Businesses Spring Term 2017: Course Outline and Syllabus

      By: Richard G. Hamermesh
      This Course Outline and Syllabus gives an overview of the Spring 2016 class Building Life Science Businesses.7 View Details
      Keywords: Healthcare Ventures; Entrepreneurial Management; Entrepreneurship; Entrepreneurs; Health Care and Treatment; Health Testing and Trials; Medical Specialties; Medical Devices and Supplies Industry; Medical Devices and Supplies Industry; Medical Devices and Supplies Industry; Asia; North America; Europe
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      Hamermesh, Richard G. "Building Life Science Businesses Spring Term 2017: Course Outline and Syllabus." Harvard Business School Course Overview Note 815-003, July 2014. (Revised January 2017.)
      • June 2014 (Revised April 2015)
      • Case

      OrthoChoice: Bundled Payments in the County of Stockholm (A)

      By: Michael E. Porter, Clifford M. Marks and Zachary C. Landman
      It was the waiting that drew the attention of the Stockholm County Council. In 2008, patients seeking a hip or knee replacement in Stockholm County faced wait times of up to two years of sometimes debilitating pain, intermittent missed work and income, and the trials... View Details
      Keywords: Bundled Payment; Health Care Quality; Health Care; Sweden; Hip Replacement; Knee Replacement; Orthopedics; Health Care and Treatment; Health Disorders; Health; Health Industry; Sweden
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      Porter, Michael E., Clifford M. Marks, and Zachary C. Landman. "OrthoChoice: Bundled Payments in the County of Stockholm (A)." Harvard Business School Case 714-514, June 2014. (Revised April 2015.)
      • Article

      Better Accounting Transforms Health Care Delivery

      By: Robert S. Kaplan and Mary L. Witkowski
      The paper describes the theory and preliminary results for an action research program that explores the implications from better measurements of health care outcomes and costs. After summarizing Porter's outcome taxonomy (Porter 2010), we illustrate how to use process... View Details
      Keywords: Activity Based Costing and Management; Research; Health Care and Treatment; Health Industry
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      Kaplan, Robert S., and Mary L. Witkowski. "Better Accounting Transforms Health Care Delivery." Accounting Horizons 28, no. 2 (June 2014): 365–383.
      • May 2014 (Revised March 2016)
      • Case

      Health City Cayman Islands

      By: Tarun Khanna and Budhaditya Gupta
      Narayana Health (NH) had been successfully delivering affordable high quality tertiary care to the masses in India through its chain of hospitals for over a decade. To encourage the adoption of the NH affordable care delivery model worldwide, Dr. Shetty, Chairman of... View Details
      Keywords: Healthcare; Emerging Economies; Innovation; India; Institutions; Pricing; Replication; Strategy; Narayana Health; Ascension; Health City Cayman Islands; Dr. Devi Shetty; International Business; Health Care and Treatment; Innovation Strategy; Innovation and Management; Disruptive Innovation; Cross-Cultural and Cross-Border Issues; Global Strategy; Knowledge Use and Leverage; Management Practices and Processes; Growth Management; Growth and Development Strategy; Market Entry and Exit; Adaptation; Adoption; India; Cayman Islands
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      Khanna, Tarun, and Budhaditya Gupta. "Health City Cayman Islands." Harvard Business School Case 714-510, May 2014. (Revised March 2016.)
      • May 2014 (Revised January 2015)
      • Case

      Vaxess Technologies, Inc.

      By: John A. Quelch and Margaret L. Rodriguez
      In February 2014, Michael Schrader, chief executive of Vaxess Technologies, Inc., was assessing the startup health care company's 2014 marketing plan. On December 31st, 2013, Vaxess had obtained an exclusive license to a series of patents for a silk protein technology... View Details
      Keywords: Vaccine; Cold Chain; Antigen; Temperature Controlled; Developing Markets; Immunization; Health Care and Treatment; Health Pandemics; Global Strategy; Supply Chain; Health; Medical Devices and Supplies Industry; Medical Devices and Supplies Industry
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      Quelch, John A., and Margaret L. Rodriguez. "Vaxess Technologies, Inc." Harvard Business School Case 514-107, May 2014. (Revised January 2015.)
      • April 2014 (Revised January 2015)
      • Background Note

      Note on Mobile Healthcare

      By: John A. Quelch and Margaret L. Rodriguez
      Delivering health care to the global population was a challenge. Health care costs accounted for ten percent of world GDP by 2013. In the U.S., health care costs were expected to top $3.1 trillion in 2014. New technologies, shortages of trained personnel and... View Details
      Keywords: Health Care; Mobile; Mobile App; Public Health; Startups; Hardware; Software; Telemedicine; Global; Medical Devices; Medical Services; Medical Solutions; Entrepreneurs; Government And Business; Technological Change; Health Care and Treatment; Entrepreneurship; Government and Politics; Technological Innovation; Applications and Software; Information Infrastructure; Health Industry; Technology Industry
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      Quelch, John A., and Margaret L. Rodriguez. "Note on Mobile Healthcare." Harvard Business School Background Note 514-122, April 2014. (Revised January 2015.)
      • March 2014 (Revised September 2017)
      • Case

      salaUno: Eliminating Needless Blindness in Mexico

      By: Richard Hamermesh, Regina Garcia Cueller and Valeria Moy
      In May 2013 the co-founders and co-CEOs of salaUno, Javier Okhuysen and Carlos Orellana, were encouraged by the results of their fledgling start-up. salaUno was founded as a for-profit enterprise in order to have the capital needed for rapid growth and to fulfill its... View Details
      Keywords: Medical Services; Developing Countries; Developing Markets; Health Care Industry; Health Services; Healthcare Ventures; Healthcare Startups; Health Care and Treatment; Health; Business Startups; Developing Countries and Economies; Growth and Development Strategy; Health Industry; Mexico; Mexico City
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      Hamermesh, Richard, Regina Garcia Cueller, and Valeria Moy. "salaUno: Eliminating Needless Blindness in Mexico." Harvard Business School Case 814-041, March 2014. (Revised September 2017.)
      • January 2014 (Revised June 2014)
      • Case

      23andMe: Genetic Testing for Consumers (A)

      By: John A. Quelch and Margaret L. Rodriguez
      On November 22, 2013, the direct-to-consumer genetic testing provider, 23andMe, received a letter from the U.S. Food and Drug Administration (FDA) ordering the company to halt the sale and promotion of its genetic testing kit. The FDA stated that the product was... View Details
      Keywords: Public Health; Genome Testing; Health Care; Ancestry; 23andMe; Marketing; Product Launch; Health; Health Care and Treatment; Health Testing and Trials; Genetics; Strategy; Health Industry; United States
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      Quelch, John A., and Margaret L. Rodriguez. "23andMe: Genetic Testing for Consumers (A)." Harvard Business School Case 514-086, January 2014. (Revised June 2014.)
      • January 2014
      • Supplement

      Fred Khosravi and AccessClosure (C)

      By: Richard Hamermesh and Lauren Barley
      On September 11, 2013, the three-judge panel of the U.S. Court of Appeals for the Federal Circuit denied St. Jude's request to rehear an appeal on the "double patenting" ruling for the '439 patent. Further, it removed the injunction threat that was hanging over the... View Details
      Keywords: Medical Devices; Vascular Closure Device; Patent Litigation; Patenting; Biomedical Research; Biotechnology; Biotech; Technological Innovation; Patents; Health Care and Treatment; Biotechnology Industry; United States
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      Hamermesh, Richard, and Lauren Barley. "Fred Khosravi and AccessClosure (C)." Harvard Business School Supplement 814-074, January 2014.
      • January 2014 (Revised December 2014)
      • Case

      GenapSys: Business Models for the Genome

      By: Richard G. Hamermesh, Joseph B. Fuller and Matthew Preble

      GenapSys, a California-based startup, was soon to release a new DNA sequencer that the company's founder, Hesaam Esfandyarpour, believed was truly revolutionary. The sequencer would be substantially less expensive—potentially costing just a few thousand dollars—and... View Details

      Keywords: DNA Sequencing; Life Sciences; Business Model; Innovation & Entrepreneurship; Health Care and Treatment; Genetics; Business Strategy; Medical Devices and Supplies Industry; Medical Devices and Supplies Industry; Medical Devices and Supplies Industry; Medical Devices and Supplies Industry; Medical Devices and Supplies Industry; United States
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      Hamermesh, Richard G., Joseph B. Fuller, and Matthew Preble. "GenapSys: Business Models for the Genome." Harvard Business School Case 814-050, January 2014. (Revised December 2014.)
      • January–February 2014
      • Other Article

      Barriers to Health Care Innovation: Regina Herzlinger Warns That Innovators Need to Know What Obstacles They Face and How to Overcome Them

      By: Regina E. Herzlinger
      Health care in the United States and in most other developed countries is ailing, says Regina E. Herzlinger. A chaired professor of business administration specializing in health care at Harvard Business School, Herzlinger says that although the world has witnessed... View Details
      Keywords: Healthcare; Healthcare IT; Innovation; Health Care and Treatment; Health; Information Technology; Innovation and Invention; Health Industry; Technology Industry; United States
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      Herzlinger, Regina E. "Barriers to Health Care Innovation: Regina Herzlinger Warns That Innovators Need to Know What Obstacles They Face and How to Overcome Them." IEEE Pulse 5, no. 1 (January–February 2014): 43–45.
      • Article

      Applying KISS to Healthcare Information Technology

      By: Regina E. Herzlinger, Margo Seltzer and Mark Gaynor
      Current public and private healthcare information technology initiatives have failed to achieve secure integration among providers. Applying the "keep it simple, stupid" principle offers the key guidance for solving this problem. View Details
      Keywords: Technology; Health Care; Public Health; Information Technology Industry; Computer Networks; Computer Services Industries; Software; Hardware; Medical Services; Health Care and Treatment; Information Technology; Applications and Software; Information Infrastructure; Standards; Health Industry; Technology Industry; United States
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      Herzlinger, Regina E., Margo Seltzer, and Mark Gaynor. "Applying KISS to Healthcare Information Technology." Computer 46, no. 11 (November 2013): 72–74.
      • October 2013 (Revised April 2015)
      • Case

      Myomo: Getting Sales in Motion

      By: Frank V. Cespedes, Shikhar Ghosh and Matthew Preble
      In late 2012, the management team of Myomo, a startup which had designed a unique myoelectric arm brace for patients with dysfunctional arms, was deciding which of the three sales models the company had tested to pursue as its sales strategy going forward. Each model... View Details
      Keywords: Technological Innovation; Information Technology; Marketing Strategy; Decision Choices and Conditions; Health Care and Treatment; Business Startups; Sales; Growth and Development Strategy; Medical Devices and Supplies Industry; Medical Devices and Supplies Industry
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      Cespedes, Frank V., Shikhar Ghosh, and Matthew Preble. "Myomo: Getting Sales in Motion." Harvard Business School Case 814-034, October 2013. (Revised April 2015.)
      • October 2013
      • Case

      FasterCures: Removing Barriers to Treatments

      By: Richard G. Hamermesh and James Weber

      In mid-2013, as FasterCures celebrated its 10th anniversary as a center of the Milken Institute, Executive Director Margaret Anderson thought about what the organization should do to ensure it had even more impact in its next 10 years. FasterCures was a non-profit... View Details

      Keywords: Health Care; Health Care Industry; Health Care Policy; Health Services; Healthcare; Healthcare Reform; Healthcare Ventures; Nonprofit; Non-profit Management; Not-for-profit; Incubator; Accelerator; Venture Philanthropy; Medical Services; Medical Solutions; Medical Research; Medical Treatment; Clinical Trials; Drug Reimbursement; Early Stage; Early Stage Research Funding; Early Stage Funding; Milken Institute; Michael Milken; David Baltimore; Partnering For Cures; National Institutes Of Health; Cancer Care In The U.S.; Cancer Care Services; Policy-making; Health Care and Treatment; Health; Health Testing and Trials; Entrepreneurship; Social Entrepreneurship; Nonprofit Organizations; Policy; Health Industry; United States; District of Columbia
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      Hamermesh, Richard G., and James Weber. "FasterCures: Removing Barriers to Treatments." Harvard Business School Case 814-003, October 2013.
      • October 2013 (Revised January 2014)
      • Supplement

      Fred Khosravi and AccessClosure (B)

      By: Richard G. Hamermesh and Lauren Barley
      It was January 2013, and Fred Khosravi, chairman of the board of AccessClosure Inc., wondered what the new year had in store for him and AccessClosure, the company he founded in late 2002. Khosravi was cautiously optimistic—the Mountain View, California-based medical... View Details
      Keywords: Medical Devices; Vascular Closure Device; Patent Litigation; Patenting; Biomedical Research; Biotechnology; Biotech; Technological Innovation; Patents; Health Care and Treatment; Biotechnology Industry; United States; California
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      Hamermesh, Richard G., and Lauren Barley. "Fred Khosravi and AccessClosure (B)." Harvard Business School Supplement 814-038, October 2013. (Revised January 2014.)
      • October 2013
      • Article

      The Strategy That Will Fix Health Care

      By: Michael E. Porter and Thomas H. Lee
      In health care, the days of business as usual are over. Around the world, every health care system is struggling with rising costs and uneven quality, despite the hard work of well-intentioned, well-trained clinicians. Health care leaders and policy makers have tried... View Details
      Keywords: Organizational Change and Adaptation; Strategy; Value; Customer Focus and Relationships; Health Care and Treatment; Health Industry
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      Porter, Michael E., and Thomas H. Lee. "The Strategy That Will Fix Health Care." Harvard Business Review 91, no. 10 (October 2013): 50–70.
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