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September 2020 (Revised February 2021)
Case

Zameer Kassam Fine Jewelry: Engaging Clients

By: Ryan W. Buell and Amy Klopfenstein

Zameer Kassam Fine Jewelry (ZKFJ) designs custom engagement rings that tell the story of a couple’s relationship. The case describes the company’s process for engaging clients, which has historically been a relatively offline, high-touch experience. Obliged by... View Details

Keywords: Customer Engagement; Service Delivery; Health Pandemics; Internet and the Web; Customer Satisfaction; Organizational Change and Adaptation; Growth and Development; Retail Industry

September 2020
Article

Regulatory Sandboxes: A Cure for mHealth Pilotitis?

By: Abhishek Bhatia, Rahul Matthan, Tarun Khanna and Satchit Balsari

Mobile health (mHealth) and related digital health interventions in the past decade have not always scaled globally as anticipated earlier despite large investments by governments and philanthropic foundations. The implementation of digital health tools has suffered... View Details

Keywords: COVID-19; mHealth; Digital Health; Design Thinking; Regulation; Intervention; Regulatory Sandbox; Health Care and Treatment; Technological Innovation; Design; Governing Rules, Regulations, and Reforms; India

September–October 2020
Article

The Past, Present, and (Near) Future of Gene Therapy and Gene Editing

By: Julia Pian, Amitabh Chandra and Ariel Dora Stern

Emerging gene therapy and gene-editing technologies will have a growing impact on patient lives and health-care delivery. We analyzed a decade of data on clinical trials and venture capital investments to understand the likely trajectory of genetically focused... View Details

Keywords: Gene Therapy; Gene Editing; Impact; Health Care and Treatment; Technological Innovation; Health Testing and Trials; Venture Capital; Change

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August 2020
Case

Zoom Video Communications: Eric Yuan's Leadership During COVID-19

By: Scott Duke Kominers, Christopher Stanton, Andy Wu and George Gonzalez

In the first half of 2020, worldwide lockdowns caused by the COVID-19 pandemic brought explosive growth to the Zoom Video Communications platform, as people replaced in-person work and social events with videoconferencing. Months into the pandemic, CEO Eric Yuan... View Details

Keywords: Transformation; Communication Technology; Customer Value and Value Chain; Values and Beliefs; Technological Innovation; Leadership; Crisis Management; Organizational Culture; Working Conditions; Strategy; Information Technology; Applications and Software; Technology Adoption; Health Pandemics; Technology Industry; United States; California

2020
Book

Work, Mate, Marry, Love: How Machines Shape Our Human Destiny

By: Debora L. Spar

Covering a time frame that ranges from 8000 BC to the present, and drawing upon both Marxist and feminist theories, the book argues that nearly all the decisions we make in our most intimate lives—whom to marry, how to have children, how to have sex, how to think about... View Details

July 2020
Technical Note

Digital Natives Growing Without a Sales Force

By: Das Narayandas, Michael Norris and Amram Migdal

This brief case describes the rise of so-called digital natives (also called born-in-digital) in the 2000s and 2010s that successfully grew without a sales force. The case highlights the emergence of business-to-business Internet and cloud-based companies and their... View Details

July 15, 2020
Article

How to Get People to Actually Use Contact-Tracing Apps

By: Chiara Farronato, Marco Iansiti, Marcin Bartosiak, Stefano Denicolai, Luca Ferretti and Roberto Fontana

The broad adoption of contact-tracing apps would greatly help combat the spread of COVID-19. But a number of barriers—especially privacy concerns—have hindered progress in many countries that can’t or won’t mandate adoption. A solution is to start with small... View Details

Keywords: COVID-19; Contact Tracing; Apps; Privacy; Health Pandemics; Behavior; Technology Adoption; Applications and Software

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2024
Working Paper

Cephalosporins—Fighting Hospital Infections: Case Histories of Transformational Advances

By: Amar Bhidé, Srikant Datar and Katherine Stebbins

This case history describes the development of three generations of cephalosporins – antibiotics that have significantly reduced hospital infections. Specifically, we chronicle how: 1) Early (pre-cephalosporin) antibiotics were developed in the first half of the 20th... View Details

Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms

2024
Working Paper

Prozac—Controversial Blockbuster: Case Histories of Transformational Advances

By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins

This case history describes the development of Prozac, a blockbuster drug that transformed the treatment of depression – and became a cultural phenomenon in the United States. Specifically, we chronicle the: 1) prior treatments for depression and the research that... View Details

Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms

2024
Working Paper

Tamoxifen—Reducing Breast Cancer Risks: Case Histories of Transformational Advances

By: Amar Bhidé, Srikant Datar and Katherine Stebbins

We describe the development of tamoxifen, considered a “gold standard” treatment for millions of breast cancer patients. Specifically, we describe breast cancer treatments before tamoxifen’s development; the initial development of tamoxifen from 1960 to 1973;... View Details

Keywords: Health Care and Treatment; Technological Innovation; Innovation and Invention; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Governing Rules, Regulations, and Reforms

June 2020 (Revised January 2024)
Case

TraceTogether

By: Mitchell B. Weiss and Sarah Mehta

By April 7, 2020, over 1.4 million people worldwide had contracted the novel coronavirus (COVID-19). Governments raced to curb the spread of COVID-19 by scaling up testing, quarantining those infected, and tracing their possible contacts. It had taken Singapore’s... View Details

Keywords: COVID-19; Contact Tracing; Government Administration; Crisis Management; Health; Health Pandemics; Innovation and Invention; Innovation Leadership; Innovation Strategy; Technological Innovation; Social Issues; Information Technology; Mobile and Wireless Technology; Applications and Software; Technology Adoption; Health Industry; Health Industry; Singapore

May 8, 2020
Article

Which Covid-19 Data Can You Trust?

By: Satchit Balsari, Caroline Buckee and Tarun Khanna

The COVID-19 pandemic has produced a tidal wave of data, but how much of it is any good? And as a layperson, how can you sort the good from the bad? The authors suggest a few strategies for dividing the useful data from the misleading: Beware of data that’s too broad... View Details

Keywords: COVID-19 Pandemic; Health Pandemics; Analytics and Data Science

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May–June 2020
Article

The Agenda for the Next Generation of Health Care Information Technology

By: Thomas W. Feeley, Zachary Landman and Michael E. Porter

As the diffusion of value-based health care efforts accelerates globally, the need for interoperable information technology systems that support value-based care is essential. Such systems are needed to facilitate dramatic improvements in patient outcomes and... View Details

Keywords: Value-based Health Care; Health Care and Treatment; Information Technology; Integration; Performance Improvement; Performance Efficiency

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2020
Book

Healthy Buildings: How Indoor Spaces Drive Performance and Productivity

By: Joseph Allen and John D. Macomber

By the time you reach 80, you will have spent 72 years of your life indoors. Like it or not, humans have become an indoor species. This means that the people who design, build, and maintain our buildings can have a major impact on our health.
Ever feel tired... View Details

Keywords: Architecture; Real Estate Development; Air Pollution; Air Quality; Public Health; Productivity Gains; Buildings and Facilities; Health; Pollutants; Performance Productivity; Construction Industry

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March 2020 (Revised June 2023)
Case

EyeControl: Inspiring Communication

By: Paul A. Gompers and Danielle Golan

Eye-controlled communication device startup EyeControl was founded in Tel Aviv, Israel in 2016 by cofounders with a shared personal connection to locked-in syndrome—a neurological disorder that left sufferers cognitively sound, yet paralyzed, with the exception of eye... View Details

Keywords: Health Disorders; Communication Technology; Business Startups; Expansion; Finance; Decision Making; Social Enterprise; Medical Devices and Supplies Industry

February 2020 (Revised January 2024)
Case

Wellthy: The Economics of Caring

By: Brian L. Trelstad and Joseph B. Fuller

In 2014, Lindsay Jurist-Rosner (MBA ’09) founded Wellthy, a B2C business that coordinates care for working professionals seeking help to support loved ones with chronic diseases or aging parents. With personal experience as a young professional providing care for her... View Details

Keywords: B2B Vs. B2C; Future Of Work; Health; Social Entrepreneurship; Growth and Development Strategy; Health Industry; United States

January 2020 (Revised March 2020)
Case

LOLA: Do You Know What's in Your Tampon?

By: Leonard A. Schlesinger and Aldo Sesia

LOLA is a direct-to-consumer (DTC) business launched in 2015. What started as a company to provide women with organic and transparent material-labeled tampons via a subscription model, had, by 2019 evolved to include additional menstrual and sexual wellness products.... View Details

Keywords: Direct-to-consumer; Channels; Disruption; Business Model; Brands and Branding; Internet and the Web; Strategy; Retail Industry; United States; Canada

December 2019 (Revised July 2020)
Case

Ray White

By: Boris Groysberg and Tricia Gregg

Ray White is an Australian real estate business that has been owned and operated by the White family for four generations. The business has expanded and prospered. However, as the industry faces new challenges and opportunities, how should the White family respond?... View Details

Keywords: Crisis; COVID-19; Pandemic; Family Business; Entrepreneurship; Leadership; Disruption; Information Technology; Health Pandemics; Crisis Management; Real Estate Industry; Australia

October 2019 (Revised December 2019)
Supplement

Extend Fertility: Conceiving the Market for Egg Preservation (B)

By: Debora L. Spar and Olivia Hull

Keywords: Strategy; Information Technology; Business Startups; Entrepreneurship; Innovation Strategy; Technological Innovation; Commercialization; Science-Based Business; Marketing Strategy; Business Plan; Product Marketing; Product Launch; Product Positioning; Mission and Purpose; Personal Development and Career; Social Issues; Integration; Health; Health Industry

October 2019 (Revised April 2020)
Background Note

Note on Funding Deep Tech Startups

By: Karim Lakhani, Peter Barrett and Noubar Afeyan

This Background Note provides essential information on funding deep technologies—those technologies that were inherently capital intensive, time consuming, risky, and potentially disruptive. Both dilutive and non-dilutive sources of investment are highlighted, along... View Details

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