Publications

August 2015 (Revised June 2021)
Case

Amazon.com, 2021

By: John R. Wells, Benjamin Weinstock, Gabriel Ellsworth and Galen Danskin

In February 2021, Amazon announced 2020 operating profits of $22,899 million, up from $2,233 million in 2015, on sales of $386 billion, up from $107 billion five years earlier (see Exhibit 1). The shareholders expressed their satisfaction (see Exhibit 2), but not all... View Details

28 Feb 2017
First Look

First Look at New Research, February 28

interactions to remote medical scribes, thus freeing doctors from the burden of having to manually input information into an electronic medical record (EMR) and giving them additional time to focus on... View Details

Keywords: Sean Silverthorne

03 Jun 2020
Research & Ideas

Who Guarantees Your Workplace Is Safe for Return?

Here are key requirements to ask of any service provider offering to certify your work setting as a healthy building. These best practices apply for employers, employees, and customers alike. Our research over many decades in public View Details

Keywords: by John Macomber and Joseph Allen; Real Estate

Article

Defining the Value Framework for Prostate Brachytherapy Using Patient-Centered Outcome Metrics and Time-Driven Activity-Based Costing

By: N.G. Thaker, T.J. Pugh, U. Mahmood, S. Choi, T.E. Spinks, N.E. Martin, T.T. Sio, R.J. Kudchadker, R. S. Kaplan, D.A. Kuban, D.A. Swanson, P.F. Orio, M.J. Zelefsky, B.W. Cox, L. Potters, T.A. Buchholz, T.W. Feeley and S.J. Frank

PURPOSE: Value, defined as outcomes over costs, has been proposed as a measure to evaluate prostate cancer (PCa) treatments. We analyzed standardized outcomes and time-driven activity-based costing (TDABC) for prostate brachytherapy (PBT) to define a value... View Details

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27 Jun 2017
First Look

First Look at New Research and Ideas, June 27

and elsewhere. Yet the book shows that these entrepreneurs contributed significantly to the growth of environmental awareness among consumers, business leaders, and others. However the Earth's environmental health has continued to... View Details

Keywords: Sean Silverthorne

June 2023
Case

Verve Therapeutics: Taking DNA Editing to Heart

By: Shikhar Ghosh and Shweta Bagai

Verve Therapeutics, a public biotech company based in Boston, created a novel approach to addressing cardiovascular disease (CVD) - a leading cause of deaths globally. The company's approach was a single shot treatment to permanently lower cholesterol, thus reducing... View Details

Keywords: AI; Genetic Engineering; Medicine; Health Care and Treatment; Genetics; Innovation Strategy; Business and Stakeholder Relations; Medical Specialties; Innovation and Invention; Entrepreneurship; Biotechnology Industry

15 Aug 2006
First Look

First Look: August 15, 2006

carburetors. Download working paper: http://www.hbs.edu/research/pdf/07-009.pdf Cases & Course MaterialsInnovating in Health Care—Framework Harvard Business School Note 306-042 Contains the framework for the second-year Innovating... View Details

Keywords: Sean Silverthorne

February 2006 (Revised August 2006)
Case

deCODE Genetics: Hunting for Genes to Develop Drugs

By: Debora L. Spar

In 1996, Kari Stefansson launched a new kind of biotechnology company and a whole new way of attacking diseases. Based in Iceland, his firm, deCODE Genetics, plans to identify the individual genetic markers that lead to society's most prevalent diseases. To do so, it... View Details

Keywords: Information; Innovation Strategy; Genetics; Ethics; Health Disorders; Biotechnology Industry; Iceland

02 Apr 2015
Research & Ideas

Digital Summit Explores the New Economy

difficult to have innovation without data—which is one reason why the health care industry in the United States is too expensive. One remedy: Make the patient the customer. who Has The Power In The Music Industry? With inexpensive View Details

Article

Individuals' Decision to Co-Donate or Donate Alone: An Archival Study of Married Whole Body Donors in Hawaii

By: Michel Anteby, Filiz Garip, Paul V. Martorana and Scott Lozanoff

Background: Human cadavers are crucial to numerous aspects of health care, including initial and continuing training of medical doctors and advancement of medical research. Concerns have periodically been raised about the limited number of whole body... View Details

Keywords: Decisions; Health Care and Treatment; Personal Characteristics; Philanthropy and Charitable Giving; Health Industry; Hawaii

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30 Oct 2012
First Look

First Look: October 30

School Case 712-496 In 2006, surgeon Ara Darzi identified several key areas, including acute stroke care, for improving health care across London. In response to his seminal call to action, stroke care was reorganized around eight... View Details

Keywords: Sean Silverthorne

October 2007
Case

Colgate Max Fresh: Global Brand Roll-Out

By: John A. Quelch

In February 2005, Nigel Burton, in his third year as president of global oral care at Colgate-Palmolive Company (CP), had every reason to feel optimistic. Worldwide market shares were strong and Colgate Max Fresh (CMF), a new toothpaste that had helped drive Colgate to... View Details

Keywords: Marketing Strategy; Product Launch; Global Strategy; Brands and Branding; Health Industry; Health Industry; China; Mexico

June 2015 (Revised August 2016)
Case

Qualcomm Inc., 2009-2015

By: David B. Yoffie

In the years after 2009, Qualcomm navigated the wireless industry's transition from 3G to 4G, retaining its technological leadership and experiencing dramatic growth in revenue and profit. In March 2014, Qualcomm appointed a new CEO, Steve Mollenkopf, who had to... View Details

Keywords: Communication Technologies; Technology; Wireless Technologies; Mobile and Wireless Technology; Strategy; Communication Technology; Competitive Strategy; Change Management; Electronics Industry; Electronics Industry; California

April 2024
Article

A Machine Learning Algorithm Predicting Risk of Dilating VUR among Infants with Hydronephrosis Using UTD Classification

By: Hsin-Hsiao Scott Wang, Michael Lingzhi Li, Dylan Cahill, John Panagides, Tanya Logvinenko, Jeanne Chow and Caleb Nelson

Backgrounds: Urinary Tract Dilation (UTD) classification has been designed to be a more objective grading system to evaluate antenatal and post-natal UTD. Due to unclear association between UTD classifications to specific anomalies such as vesico-ureteral reflux (VUR),... View Details

Keywords: Health Disorders; Health Testing and Trials; AI and Machine Learning; Health Industry

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July 2023
Case

Moderna: Everything, Everywhere, All at Once

By: Satish Tadikonda, Shikhar Ghosh and William Marks

Coming out of the COVID-19 pandemic, Moderna was riding the successes of developing a vaccine in record time and helping stem the tide of the crisis. However, the company had grown at an incredible rate, more than doubled its number of employees, and had to put on hold... View Details

Keywords: Health Pandemics; Selection and Staffing; Growth Management; Management Succession; Retirement; Technological Innovation; Corporate Strategy; Biotechnology Industry