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  • 12 Mar 2013
  • First Look

First Look: March 12

  PublicationsLocal Industrial Structures and Female Entrepreneurship in India Authors:Ghani, Ejaz, William R. Kerr, and Stephen D. O'Connell Publication:Journal of Economic Geography Abstract We analyze the spatial determinants of female... View Details
Keywords: Sean Silverthorne
  • January 2017
  • Case

Danaher Corporation, 2007–2017

By: John R. Wells and Gabriel Ellsworth
On July 2, 2016, Danaher Corporation completed the spinoff of Fortive Corporation. The previous day, Danaher’s stock price had reached an all-time high. In 2015, Danaher had decided to split off its test and measurement, fuel and fleet management, and automation... View Details
Keywords: Danaher; Fortive; Larry Culp; Beckman Coulter; Pall; Life Sciences; Diagnostics; Environmental Operations; Water Management; Dental; Testing; Measurement; Fuel; Fleet Management; Automation; Toolmaking; Tools; Disease Management; Continuous Improvement; Toyota Production System; Divestiture; Spinoffs; Spin-off; Networks; Acquisition; Mergers and Acquisitions; Business Conglomerates; Business Divisions; Business Subsidiaries; Business Units; Business Growth and Maturation; Business Model; For-Profit Firms; Joint Ventures; Restructuring; Engineering; Chemicals; Construction; Machinery and Machining; Profit; Revenue; Globalized Firms and Management; Multinational Firms and Management; Health; Health Care and Treatment; Health Disorders; Medical Specialties; Business History; Job Cuts and Outsourcing; Business or Company Management; Growth and Development Strategy; Management Analysis, Tools, and Techniques; Management Practices and Processes; Management Succession; Management Systems; Resource Allocation; Market Entry and Exit; Measurement and Metrics; Logistics; Business Processes; Organizational Change and Adaptation; Public Ownership; Problems and Challenges; Science; Genetics; Natural Environment; Wastes and Waste Processing; Science-Based Business; Opportunities; Strategy; Adaptation; Business Strategy; Competition; Competitive Strategy; Competitive Advantage; Consolidation; Corporate Strategy; Diversification; Expansion; Technology; Software; Technology Networks; Technology Platform; Value; Valuation; Aerospace Industry; Aerospace Industry; Aerospace Industry; Aerospace Industry; Aerospace Industry; Aerospace Industry; Aerospace Industry; Aerospace Industry; Aerospace Industry; Aerospace Industry; Aerospace Industry; Aerospace Industry; Aerospace Industry; Aerospace Industry; Aerospace Industry; Aerospace Industry; Aerospace Industry; Aerospace Industry; Aerospace Industry; Aerospace Industry; Aerospace Industry; Aerospace Industry; Aerospace Industry; United States; District of Columbia
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  • 14 Sep 2010
  • First Look

First Look: September 14, 2010

involved in the production of clean energy. One of the key bottlenecks threatening innovation in energy production is the inability of VCs to exit their investments at the appropriate time. This hurdle did exist in industries such as... View Details
Keywords: Sean Silverthorne
  • September 2008 (Revised July 2012)
  • Case

Khosla Ventures: Biofuels Strategy

By: Joseph B. Lassiter III, William A. Sahlman and Alison Berkley Wagonfeld
By 2008, a number of the firm's early cleantech investments were showing promise, and the companies were starting to need significantly more money to create the massive scale required in the energy sector. As Khosla thought about the hundreds of millions of dollars... View Details
Keywords: Entrepreneurial Marketing; Entrepreneurial Finance; New Product Development; Partnerships; Entrepreneurial Management; Venture Capital; Strategy; Partners and Partnerships; Renewable Energy; Entrepreneurship; Investment Funds; Environmental Sustainability; Product Development; Biotechnology Industry; Biotechnology Industry
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  • September 2003 (Revised March 2007)
  • Case

Direvo Biotech AG

Describes the financing and growth decisions facing Direvo, a young German biotech firm with a customer/partner that wants to become an investor. Also discusses the business model for Direvo's directed evolution technology, with applications in both industrial enzymes... View Details
Keywords: Business Model; Decisions; Business Exit or Shutdown; Value; Business Startups; Biotechnology Industry; Germany
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  • November 2017
  • Case

Passion and Strategy: Novozymes' Embrace of the UN Sustainable Development Goals

By: Andy Zelleke and Emilie Billaud
This case explores the sustainability efforts at Novozymes, the world's largest and oldest producer of industrial enzymes. In 2015, the Danish company became the world’s first company known to have crafted a new corporate strategy based on the United Nations... View Details
Keywords: Corporate Governance; Transformation; Environmental Sustainability; Corporate Social Responsibility and Impact; Mission and Purpose; Business and Shareholder Relations; Business and Stakeholder Relations; Business Strategy; Organizational Culture; Organizational Change and Adaptation; Biotechnology Industry; Europe; Denmark
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  • 30 May 2007
  • Research & Ideas

Health Care Under a Research Microscope

The $2 trillion health care system is one of the United States' largest industries—but one of its worst performing by almost any measure other than technological innovation. The problems are painful, including escalating costs, expensive insurance premiums, lack of... View Details
Keywords: by Sean Silverthorne; Biotechnology; Biotechnology
  • January 2014 (Revised December 2014)
  • Case

GenapSys: Business Models for the Genome

By: Richard G. Hamermesh, Joseph B. Fuller and Matthew Preble

GenapSys, a California-based startup, was soon to release a new DNA sequencer that the company's founder, Hesaam Esfandyarpour, believed was truly revolutionary. The sequencer would be substantially less expensive—potentially costing just a few thousand dollars—and... View Details

Keywords: DNA Sequencing; Life Sciences; Business Model; Innovation ＆ Entrepreneurship; Health Care and Treatment; Genetics; Business Strategy; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry; United States
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  • 09 Apr 2012
  • Research & Ideas

Who Sways the USDA on GMO Approvals?

Traditional Theories Break Down As Hiatt began investigating, he found that traditional theories of capture such as lobbying and campaign contributions had little effect on whether any particular GMO was approved. Even more direct means of influence such as scientific... View Details
Keywords: by Michael Blanding; Biotechnology; Biotechnology; Biotechnology
  • January 2006
  • Case

Jack Strang at SequenceLabs

By: Mukti Khaire, John J. Gabarro and Lynda M. Applegate
How can entrepreneur manage his firm if things go wrong despite having a great idea, a solid team, and financial backing? Jack Strang founded a biotech firm with his friend Peter Evans, to develop molecular pathway-based "cures" for metabolic disorders. The idea was... View Details
Keywords: Corporate Entrepreneurship; Business or Company Management; Venture Capital; Factories, Labs, and Plants; Business Growth and Maturation; Failure; Biotechnology Industry
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  • 2016
  • Book

Consumers, Corporations, and Public Health: A Case-Based Approach to Sustainable Business

By: John A. Quelch
The public health footprint associated with corporate behavior has come under increased scrutiny in the last decade, with an increased expectation that private profit not come at the expense of consumer welfare.

Consumers, Corporations, and Public... View Details
Keywords: Consumer; Corporate Culture; Public Health; Consumer Behavior; Marketing Strategy; Corporate Strategy; Health; Innovation and Invention; Innovation and Management; Supply Chain Management; Advertising Industry; Advertising Industry; Advertising Industry; Advertising Industry; Advertising Industry; Advertising Industry; Advertising Industry; Advertising Industry; Advertising Industry; Advertising Industry; Advertising Industry; Advertising Industry; Advertising Industry; Advertising Industry; Advertising Industry; Advertising Industry; Advertising Industry; Advertising Industry; Advertising Industry; Advertising Industry; Advertising Industry; Asia; Oceania; North and Central America; Middle East; Latin America; Europe
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  • 26 Sep 2006
  • First Look

First Look: September 26, 2006

  Working PapersScale Without Mass: Business Process Replication and Industry Dynamics Authors:Erik Brynjolfsson, Andrew McAfee, Michael Sorell, and Feng Zhu Abstract Since the mid-1990s, productivity growth has accelerated in the U.S.... View Details
Keywords: Sean Silverthorne
  • October 2022 (Revised May 2023)
  • Case

Ginkgo Bioworks vs. Scorpion Capital: The Debate Over Related-Party Revenues

By: Aiyesha Dey, Jonas Heese, Suraj Srinivasan and Annelena Lobb
Ginkgo Bioworks, a synthetic biology company based in Boston, Massachusetts, faced divergent views on its revenue possibilities and accounting practices. After a report emerged accusing it of fraudulent accounting and lack of innovation, its share price plunged. But... View Details
Keywords: Fraud Allegations; Revenue; Reports; Accounting Audits; Innovation and Management; Investment; Biotechnology Industry; Boston
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  • June 2023
  • Case

Verve Therapeutics: Taking DNA Editing to Heart

By: Shikhar Ghosh and Shweta Bagai
Verve Therapeutics, a public biotech company based in Boston, created a novel approach to addressing cardiovascular disease (CVD) - a leading cause of deaths globally. The company's approach was a single shot treatment to permanently lower cholesterol, thus reducing... View Details
Keywords: AI; Genetic Engineering; Medicine; Health Care and Treatment; Genetics; Innovation Strategy; Business and Stakeholder Relations; Medical Specialties; Innovation and Invention; Entrepreneurship; Biotechnology Industry
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  • 02 Feb 2016
  • First Look

February 2, 2016

Interorganizational Network Forms By: Tatarynowicz, Adam, Maxim Sytch, and Ranjay Gulati Abstract—This study investigates the origins of variation in the structures of interorganizational networks across industries. We combine empirical analyses of existing... View Details
Keywords: Sean Silverthorne
  • Research Summary

Knowledge flows and capability acquisition

By: Willy C. Shih
Technological advancements are a major source of improvement in competiveness, and a firm’s incentives to invest are diminished when the knowledge generated is involuntarily dispersed to competitors.  While intellectual property rights can moderate this flow to the... View Details
Keywords: Knowledge Aspects Of Strategy; Knowledge Management; Knowledge Spillovers; Knowledge Acquisition; Manufacturing Industry; Manufacturing Industry; Manufacturing Industry; United States; China
  • 21 Apr 2009
  • First Look

First Look: April 21, 2009

institutional theory, and economic theory. Download the paper: http://www.hbs.edu/research/pdf/08-025.pdf Broadening Focus: Spillovers and the Benefits of Specialization in the Hospital Industry Authors:Jonathan R. Clark and Robert S.... View Details
Keywords: Martha Lagace
  • February 2014
  • Case

BGI: Data-driven Research

By: Willy Shih and Sen Chai
BGI has the largest installed gene-sequencing capacity in the world, and to Zhang Gengyun, general manager of the Life Sciences Division, this represented an opportunity to apply his training as a plant breeder and his early career work as a biochemist to improving... View Details
Keywords: Genomics; Gene Sequencing; Life Sciences; Plant Breeding; Human Genome Program; Beijing Genomics Institute; BGI; Rice Genome; Technological Innovation; Innovation Strategy; Research; Research and Development; Science; Genetics; Science-Based Business; Strategy; Commercialization; Corporate Strategy; Information Technology; Applications and Software; Agriculture and Agribusiness Industry; Agriculture and Agribusiness Industry; Agriculture and Agribusiness Industry; China; United States
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  • September 2010 (Revised July 2013)
  • Case

Alnylam Pharmaceuticals: Building Value from the IP Estate

By: Willy C. Shih and Sen Chai
The learning objective of this case is to help students recognize the interplay between intellectual property (IP) rights and corporate strategy. We do this by examining what is a fairly atypical circumstance today in which a single firm is able to secure what it... View Details
Keywords: Patents; Lawsuits and Litigation; Rights; Competitive Strategy; Corporate Strategy; Biotechnology Industry; Biotechnology Industry; United States
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  • January 2001
  • Case

Abgenix and the XenoMouse

By: Robert J. Dolan
Abgenix has a unique method for generating antibodies useful in treating a number of diseases, including cancer. In early 2000, the company's cancer has performed very well in animal testing and is moving to early stage human testing. Abgenix must decide whether to... View Details
Keywords: Product Development; Marketing Strategy; Health Testing and Trials; Risk and Uncertainty; Technological Innovation; Innovation Strategy; Science-Based Business; Biotechnology Industry
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