Publications

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September 2007 (Revised May 2009)
Case

Syndexa and Technology Transfer at Harvard University

By: Richard G. Hamermesh and David Kiron

Gokhan Hotamisligil is a star researcher at Harvard School of Public Health who has made groundbreaking discoveries linking fat cells, inflammation, and diabetes. He now wants to form a company to commercialize these discoveries. At the same time, Isaac Kohlberg, the... View Details

Keywords: Business Startups; Higher Education; Entrepreneurship; Innovation and Invention; Intellectual Property; Rights; Agreements and Arrangements; Science-Based Business; Commercialization; Biotechnology Industry; Health Industry

May 2006
Case

A123Systems

By: H. Kent Bowen, Kenneth P Morse and Douglass Cannon

A 123Systems was a young company that was founded on basic materials science research at the Massachusetts Institute of Technology. A co-founder of the company, Yet-Ming Chiang, was a full professor at MIT and served as scientific adviser. Intellectual property based... View Details

Keywords: Intellectual Property; Business Startups; Research and Development; Commercialization; Technological Innovation; Science-Based Business; Product Development; Battery Industry; Electronics Industry; Massachusetts

October 2004 (Revised April 2005)
Case

Lexar Media: The Digital Photography Company?

Examines growth options for a start-up that has parlayed its core technology in flash memory controllers into a rapidly growing position in the emerging digital photography industry. The new CEO must decide whether LexarMedia should maintain its identity as a digital... View Details

Keywords: Technology; Mission and Purpose; Organizational Change and Adaptation; Growth Management; Market Entry and Exit; Business Startups; Business Strategy; Technology Industry

August 2011 (Revised October 2011)
Case

PureTech Ventures in 2011

By: Andrei Hagiu, Cesar Castro and Sarah Murphy

In early May 2011, Daphne Zohar, founder and managing partner of PureTech Ventures, a life science venture creation company in Boston, MA, was reviewing a term sheet she had just received from a venture capital (VC) firm for one of PureTech's portfolio companies. The... View Details

Keywords: Business Ventures; Business Startups; Venture Capital; Investment; Innovation and Invention; Negotiation; Partners and Partnerships; Science-Based Business; Opportunities; Boston

01 Apr 2014
First Look

First Look: April 1

we find evidence that proximity is positively associated with coordination and overall performance. Download working paper: http://www.hbs.edu/faculty/Publication%20Files/14-092_0272c9fd-0da7-4bad-811c-77eb8db9ef81.pdf Competing in New Markets and the Search for a... View Details

Keywords: Sean Silverthorne

09 Sep 2014
First Look

First Look: September 9

seeking to make their business socially acceptable and a range of non-governmental groups working to promote public welfare, labor, and minority rights. In France, where a similar coalition did not emerge, consumer credit continued to be... View Details

Keywords: Sean Silverthorne

03 Jan 2007
First Look

First Look: January 3, 2007

Bureau's Longitudinal Business Database. The comprehensive micro-data allow us to study how both the entry rate and the distribution of entry sizes for new startups responded to changes in banking... View Details

Keywords: Sean Silverthorne

February 2023
Supplement

Astyanax Kanakakis at norbloc: A Founder's Experience with the DIFC Fintech Hive

By: Linda A. Hill and Lydia Begag

norbloc was founded in 2016 in Stockholm, Sweden, by Astyanax Kanakakis and his co-founders, Vitalii Demianets and Sam Saatchi. Kanakakis and Demianets got to work to address a key gap in the industry: Know Your Customer (KYC) data sharing. As the first distributed KYC... View Details

September 2019 (Revised May 2020)
Supplement

Keroche (F): Future Growth Plans

By: Ramon Casadesus-Masanell and Pippa Tubman Armerding

This case describes Keroche co-founder Tabitha Karanja’s 2012 decision to invest in additional production capacity. In November 2012, with a loan from Barclay’s bank, Keroche began constructing a new state-of-the-art beer brewery using German technology. The new plant,... View Details

July 2023
Case

Honeycomb

By: Jeffrey J. Bussgang and Kumba Sennaar

Honeycomb, an audio app enabling seniors to record stories and save family memories, suddenly draws interest from a younger user demographic. The co-founders consider pivoting to better serve this new user demographic. How should they think about strategy, brand, and... View Details

Keywords: Entrepreneurship; Venture Capital; Operations; Business Startups; Customer Focus and Relationships; Age; Brands and Branding; Technology Industry; United States

September 2016 (Revised January 2020)
Case

Pebble: Wearables Pioneer

By: David Yoffie and Allison Ciechanover

In the summer of 2016, wearables “wunderkind” and Pebble founder and CEO, Eric Migicovsky, was pleased with the young startup’s success in the five years since its founding. The Silicon Valley–based company had recently shipped its two millionth smartwatch; held the... View Details

Keywords: Competition; Strategy; Innovation Strategy; Product; Information Technology; Technological Innovation; Business Startups; Technology Industry; United States; California

October 2022
Case

Single.Earth

By: Rembrand Koning and Emer Moloney

Estonian greentech company Single.Earth is launching a nature-backed token that is linked to and funds the protection of a specific plot fo land. The first landowners had been onboarded to the company's Digital Twin, a virtual representation of the planet's natural... View Details

Keywords: Alternative Assets; Business Startups; Entrepreneurship; Climate Change; Environmental Sustainability; Green Technology; Natural Resources; Pollution; Analytics and Data Science; Marketing; Product Marketing; Product Launch; Product Positioning; Markets; Market Timing; Strategy; Green Technology Industry; Estonia

May–June 2023
Article

Should Your Start-up Be For-profit or Nonprofit?: A Guide for Social Entrepreneurs

By: Cait Brumme and Brian Trelstad

Years ago the line between nonprofit and for-profit enterprises was clear, but that has changed. Nonprofits now offer products that compete with those of the best for-profits, and for-profits can deliver as much social value as charities. Despite the blurred... View Details

Keywords: Business Startups; Social Entrepreneurship; Mission and Purpose; Nonprofit Organizations; For-Profit Firms; Decision Choices and Conditions

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January 2013 (Revised April 2015)
Case

Affinity Labs: Valuing Customer Growth

By: Joseph B. Lassiter III and Elizabeth Kind

In November 2006, Chris Michel left Military.com, which he founded in 1999, to start Affinity Labs, a global network of online communities. That month, Michel raised a Series A round of venture funding and established a partnership with Monster, which he had sold... View Details

Keywords: Mergers and Acquisitions; Business Startups; Entrepreneurship; Demand and Consumers; Partners and Partnerships; Social and Collaborative Networks; Online Technology

July 2002 (Revised March 2003)
Case

Restructuring Bulong's Project Debt

By: Benjamin C. Esty and Michael Kane

Preston Resources, a small Australian gold mining company, bought the Bulong nickel mine for A$319 million in November 1998 and financed the acquisition by issuing a US$185 million (A$294 million) project bond. At the time, mining had been underway for several months,... View Details

Keywords: Finance; Projects; Restructuring; Bonds; Borrowing and Debt; Business Startups; Insolvency and Bankruptcy; Valuation; Mining Industry; Australia

December 2000
Case

CellFor, Inc.

By: Ray A. Goldberg, Carin-Isabel Knoop, Frantz Edward Alphonse and Laure Mougeot Stroock

A new private company has developed a process to clone and multiply seeds for the forestry industry. View Details

Keywords: Business Startups; Transition; Technological Innovation; Private Ownership; Research and Development; Science-Based Business; Technology Adoption; Forestry Industry