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      • December 2022
      • Technical Note

      Risks and Opportunities from the Transition to a Low Carbon Economy: A Business Analysis Framework

      By: George Serafeim
      The transition to a low carbon economy introduces many risks and opportunities for businesses. Risks emerge from regulatory actions, such as carbon taxes and cap and trade systems, technological innovation that develop alternatives for customers making existing... View Details
      Keywords: Risk Assessment; Opportunities; Environmental Sustainability; Carbon Footprint; Risk Management; Competitive Dynamics; Business Analysis; Climate Change; Accounting; Finance; Valuation; Business and Shareholder Relations; Technological Innovation; Transition; Product Positioning; Renewable Energy; Analysis
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      Serafeim, George. "Risks and Opportunities from the Transition to a Low Carbon Economy: A Business Analysis Framework." Harvard Business School Technical Note 123-014, December 2022.
      • November 2022
      • Case

      Ajax Health: A New Model for Medical Technology Innovation

      By: Regina E. Herzlinger and Ben Creo
      This case teaches key success factors for both startup and established MedTech firms. It examines how to structure a firm to maximize innovation and financial returns with organizational structures that better align the incentives for the different skill sets... View Details
      Keywords: Business Startups; Success; Innovation Strategy; Mergers and Acquisitions; Market Entry and Exit; Financial Strategy; Business Model; Partners and Partnerships; Entrepreneurship; Private Equity; Technology Industry; Medical Devices and Supplies Industry
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      Herzlinger, Regina E., and Ben Creo. "Ajax Health: A New Model for Medical Technology Innovation." Harvard Business School Case 323-043, November 2022.
      • 2022
      • Article

      The Effects of Public and Private Equity Markets on Firm Behavior

      By: Shai Bernstein
      In this article, I review the theoretical and empirical literature on the effects of public and private equity markets on firm behavior, emphasizing the consequences that emerge from disclosure requirements, ownership concentration, and degree of firm standardization.... View Details
      Keywords: Corporate Finance And Governance; Financing Policy; Commercialization; Capital Markets; Private Equity; Public Equity; Venture Capital; Innovation and Invention; Cost of Capital
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      Bernstein, Shai. "The Effects of Public and Private Equity Markets on Firm Behavior." Annual Review of Financial Economics 14 (2022): 295–318.
      • October 2022 (Revised May 2023)
      • Case

      Ginkgo Bioworks vs. Scorpion Capital: The Debate Over Related-Party Revenues

      By: Aiyesha Dey, Jonas Heese, Suraj Srinivasan and Annelena Lobb
      Ginkgo Bioworks, a synthetic biology company based in Boston, Massachusetts, faced divergent views on its revenue possibilities and accounting practices. After a report emerged accusing it of fraudulent accounting and lack of innovation, its share price plunged. But... View Details
      Keywords: Fraud Allegations; Revenue; Reports; Accounting Audits; Innovation and Management; Investment; Biotechnology Industry; Boston
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      Dey, Aiyesha, Jonas Heese, Suraj Srinivasan, and Annelena Lobb. "Ginkgo Bioworks vs. Scorpion Capital: The Debate Over Related-Party Revenues." Harvard Business School Case 123-037, October 2022. (Revised May 2023.)
      • October 2022
      • Case

      Colette Phillips and GetKonnected!: Creating Inclusive Ecosystems

      By: Rosabeth Moss Kanter, Amy Chiu and Joyce Kim
      Colette Phillips’ marketing firm had just won the City of Boston’s 2nd largest contract in history to a Black-owned company. During the Covid-19 pandemic, Get Konnected!, the networking organization for people of color that she founded 15 years earlier and led to... View Details
      Keywords: Diversity; Ecosystem; Inclusion; People Of Color; Network; Racial Bias; Gender Bias; Entrepreneurial Ecosystem; Entrepreneur; Change; Change Barriers; Change Leadership; Community; Innovation; Pandemic; Impact; Systemic Racism; Minority-owned Businesses; Social and Collaborative Networks; Equity; Race; Small Business; Prejudice and Bias; Boston
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      Kanter, Rosabeth Moss, Amy Chiu, and Joyce Kim. "Colette Phillips and GetKonnected!: Creating Inclusive Ecosystems." Harvard Business School Case 323-035, October 2022.
      • October 2022 (Revised February 2024)
      • Case

      Masdar City: Aiming for Sustainable and Profitable Real Estate

      By: Boris Vallee and Fares Khrais
      Masdar City broke ground in 2008 and was conceived by the Abu Dhabi government to be an international beacon of innovation in sustainable energy and real estate. It was also to be a profitable investment for the government. At first glance, the two goals pulled in... View Details
      Keywords: Analysis; Business Growth And Maturation; Decisions; Public Sector; Financial Crisis; Construction; Climate Change; Green Technology; Borrowing And Debt; Corporate Finance; Capital; Capital Budgeting; Capital Structure; Cost Of Capital; Equity; REIT; Financial Management; Financial Strategy; Initial Public Offering; Innovation; Growth And Development Strategy; Emerging Markets; Urban Development; Middle East; United Arab Emirates; Sustainable Cities; Green Building; Business and Government Relations; Decision Choices and Conditions; Financing and Loans; Real Estate Industry; Construction Industry; Energy Industry; Green Technology Industry; Abu Dhabi
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      Vallee, Boris, and Fares Khrais. "Masdar City: Aiming for Sustainable and Profitable Real Estate." Harvard Business School Case 223-036, October 2022. (Revised February 2024.)
      • September 2022
      • Article

      Find and Replace: R&D Investment Following the Erosion of Existing Products

      By: Joshua L. Krieger, Xuelin Li and Richard T. Thakor
      How do innovative firms react when existing products experience negative shocks? We explore this question with detailed project-level data from drug development firms. Using FDA Public Health Advisories as idiosyncratic negative shocks to approved drugs, we first... View Details
      Keywords: R&D Investments; Drug Development; Product Shocks; M&A; Biopharmaceutical Industry; FDA; System Shocks; Research and Development; Investment; Decision Making; Pharmaceutical Industry
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      Krieger, Joshua L., Xuelin Li, and Richard T. Thakor. "Find and Replace: R&D Investment Following the Erosion of Existing Products." Management Science 68, no. 9 (September 2022): 6552–6571.
      • 2023
      • Working Paper

      Scoring and Funding Breakthrough Ideas: Evidence from a Global Pharmaceutical Company

      By: Joshua Krieger, Ramana Nanda, Ian Hunt, Aimee Reynolds and Peter Tarsa
      We study resource allocation to early-stage ideas at an internal startup program of one the largest pharmaceutical firms in the world. Our research design enables us to elicit every evaluator’s scores across five different attributes, before seeing how they would... View Details
      Keywords: Project Selection; Pharmaceuticals; Financing Innovation; Resource Allocation; Innovation and Invention; Research and Development
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      Krieger, Joshua, Ramana Nanda, Ian Hunt, Aimee Reynolds, and Peter Tarsa. "Scoring and Funding Breakthrough Ideas: Evidence from a Global Pharmaceutical Company." Harvard Business School Working Paper, No. 23-014, August 2022. (Revised November 2023.)
      • August 2022 (Revised March 2023)
      • Technical Note

      Real Estate iBuying

      By: Michael Luca, Jesse M. Shapiro and Julia Kelley
      This note provides an overview of real estate iBuying, or instant buying, a business model that involves buying homes and then reselling them at a profit. Introduced in the mid-2010s, iBuying streamlined the process of selling a home by offering instant, all-cash... View Details
      Keywords: iBuying; Profit; Business Model; Technological Innovation; Real Estate Industry
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      Luca, Michael, Jesse M. Shapiro, and Julia Kelley. "Real Estate iBuying." Harvard Business School Technical Note 923-001, August 2022. (Revised March 2023.)
      • August 2022
      • Case

      In-Q-Tel: Innovation On A Mission

      By: Joshua Lev Krieger and Josh Lerner
      In 2022, the leaders of In-Q-Tel (IQT) considered what was next for the unique mission-driven organization. Since 1999, IQT had one mission: to be the most sophisticated source of strategic technical knowledge and capabilities to the U.S. government and its allies. IQT... View Details
      Keywords: Mission and Purpose; National Security; Technological Innovation; Research; Geopolitical Units; Risk Management; Recruitment; Growth and Development Strategy; Venture Capital; Knowledge Management; Information Industry; Banking Industry
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      Krieger, Joshua Lev, and Josh Lerner. "In-Q-Tel: Innovation On A Mission." Harvard Business School Case 823-031, August 2022.
      • August 2022
      • Case

      SuperRare: Turning an NFT Marketplace into a DAO

      By: Jeffrey J. Bussgang, Scott Duke Kominers and Amy Klopfenstein
      In June 2021, John Crain and Jonathan Perkins, the founders of SuperRare, a marketplace for non-fungible tokens (NFTs), contemplate whether to transform their company into a decentralized autonomous organization (DAO). Crain and Perkins founded SuperRare in 2018 to... View Details
      Keywords: NFTs; Crypto Economy; Alternative Assets; DAOs; Arts; Governance; Governance Controls; Governing Rules, Regulations, and Reforms; Information Technology; Technology Adoption; Internet and the Web; Digital Platforms; Innovation and Invention; Technological Innovation; Disruptive Innovation; Finance; Currency; Investment; Markets; Auctions; Bids and Bidding; Demand and Consumers; Network Effects; Market Design; Market Transactions; Market Timing; Web Services Industry; North and Central America; United States
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      Bussgang, Jeffrey J., Scott Duke Kominers, and Amy Klopfenstein. "SuperRare: Turning an NFT Marketplace into a DAO." Harvard Business School Case 823-027, August 2022.
      • July 2022 (Revised February 2024)
      • Teaching Note

      The DivaCup: Navigating Distribution and Growth

      By: Ayelet Israeli
      Teaching Note for HBS Case No. 519-055. When the mother-daughter founders of DivaCup set out with a mission to disrupt the menstrual care industry with an innovative product form, they initially struggled to gain legitimacy and convince retailers to carry their unique... View Details
      Keywords: Female; Female Ceo; Female Entrepreneur; Female Protagonist; Health & Wellness; Healthcare; Price Policies; Minimum Advertised Price; Differentiation; Positioning; Growth; Health; Health Care and Treatment; Price; Disruption; Distribution; Distribution Channels; Competitive Strategy; Competition; Growth Management; Mission and Purpose; Product Development; Product Marketing; Product Launch; Product Positioning; Advertising; Business Startups; Internet and the Web; Entrepreneurship; Social Entrepreneurship; Social Issues; Social Enterprise; Retail Industry; Medical Devices and Supplies Industry; Manufacturing Industry; Health Industry; Green Technology Industry; Education Industry; Distribution Industry; Consumer Products Industry; Canada; United States; United Kingdom
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      Israeli, Ayelet. "The DivaCup: Navigating Distribution and Growth." Harvard Business School Teaching Note 523-008, July 2022. (Revised February 2024.)
      • 2022
      • Article

      Science-based Entrepreneurship in India: A Policy Glass (as yet) Quarter-Full

      By: Tarun Khanna
      India is celebrated for a resurgence of de novo entrepreneurship in recent decades. Entrants have engaged in creative risk-taking to provide market-based solutions for private or social needs despite not being scions of wealthy industrial or business families. In this... View Details
      Keywords: Entrepreneurship; Innovation and Invention; Science; Policy; Investment
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      Khanna, Tarun. "Science-based Entrepreneurship in India: A Policy Glass (as yet) Quarter-Full." India Policy Forum 19 (2022): 1–53.
      • June 2022
      • Teaching Plan

      GreenLight Fund

      By: Brian Trelstad and Mel Martin
      Teaching Note for HBS Case No. 320-053. As Tara Noland, the Executive Director (ED) of GreenLight Cincinnati, reflected on her first few years on the job. Noland had delivered on what she had been hired to do in the city: work with leading philanthropists and nonprofit... View Details
      Keywords: Philanthropy; Venture Philanthropy; Replication; Philanthropy and Charitable Giving; Venture Capital; Social Issues; Decision Making; Cincinnati
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      Trelstad, Brian, and Mel Martin. "GreenLight Fund." Harvard Business School Teaching Plan 322-089, June 2022.
      • June 2022
      • Teaching Note

      Bespoken Spirits: Disrupting Distilling

      By: Benjamin C. Esty and Daniel Fisher
      Teaching Note for HBS Case No. 721-419. On October 7, 2020, Bespoken Spirits publicly announced it had received $2.6 million of seed funding for its “sustainable maturation process,” a process that could produce award-winning whiskeys in just days rather than years... View Details
      Keywords: B2B Vs. B2C; Technological Innovation; Business Startups; Cost Management; Business Model; Consumer Products Industry; Food and Beverage Industry; Service Industry
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      Esty, Benjamin C., and Daniel Fisher. "Bespoken Spirits: Disrupting Distilling." Harvard Business School Teaching Note 722-457, June 2022.
      • June 2022
      • Article

      The Use and Misuse of Patent Data: Issues for Finance and Beyond

      By: Josh Lerner and Amit Seru
      Patents and citations are powerful tools for understanding innovation increasingly used in financial economics (and management research more broadly). Biases may result, however, from the interactions between the truncation of patents and citations and the changing... View Details
      Keywords: Patents; Analytics and Data Science; Corporate Finance; Research
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      Lerner, Josh, and Amit Seru. "The Use and Misuse of Patent Data: Issues for Finance and Beyond." Review of Financial Studies 35, no. 6 (June 2022): 2667–2704.
      • May 2022
      • Supplement

      Maestro Pizza (B): The Competition Awakens

      By: Ramon Casadesus-Masanell and Fares Khrais
      Maestro pizza opened its first store in 2013 after its founder, Khalid Al Omran, recognized an opportunity in Saudi Arabia to offer high quality pizza at affordable prices. The business grew rapidly and under the radar at first, but soon enough caught the attention of... View Details
      Keywords: Competitive Strategy; Competitive Advantage; Competition; Market Entry and Exit; Emerging Markets; Business Startups; Corporate Entrepreneurship; Product Positioning; Disruption; Disruptive Innovation; Advertising; Advertising Campaigns; Social Media; Forecasting and Prediction; Crisis Management; Growth and Development Strategy; Brands and Branding; Product Development; Production; Service Delivery; Business Growth and Maturation; Financial Statements; Cost Management; Analysis; Quality; Performance Consistency; Customer Satisfaction; Profit; Family Ownership; Food and Beverage Industry; Saudi Arabia; Middle East
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      Casadesus-Masanell, Ramon, and Fares Khrais. "Maestro Pizza (B): The Competition Awakens." Harvard Business School Supplement 722-400, May 2022.
      • May 2022
      • Supplement

      Maestro Pizza (C): Taking the Fight Outside

      By: Ramon Casadesus-Masanell and Fares Khrais
      Maestro pizza opened its first store in 2013 after its founder, Khalid Al Omran, recognized an opportunity in Saudi Arabia to offer high quality pizza at affordable prices. The business grew rapidly and under the radar at first, but soon enough caught the attention of... View Details
      Keywords: Competitive Strategy; Competitive Advantage; Competition; Market Entry and Exit; Emerging Markets; Business Startups; Corporate Entrepreneurship; Product Positioning; Disruption; Disruptive Innovation; Advertising; Advertising Campaigns; Social Media; Forecasting and Prediction; Crisis Management; Growth and Development Strategy; Brands and Branding; Product Development; Production; Service Delivery; Business Growth and Maturation; Financial Statements; Cost Management; Analysis; Quality; Performance Consistency; Customer Satisfaction; Profit; Family Ownership; Food and Beverage Industry; Middle East; Saudi Arabia
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      Casadesus-Masanell, Ramon, and Fares Khrais. "Maestro Pizza (C): Taking the Fight Outside." Harvard Business School Supplement 722-401, May 2022.
      • May 2022
      • Case

      Maestro Pizza: Coming in Hot!

      By: Ramon Casadesus-Masanell and Fares Khrais
      Maestro Pizza opened its first store in 2013 after its founder, Khalid Al Omran, recognized an opportunity in Saudi Arabia to offer high quality pizza at affordable prices. The business grew rapidly and under the radar at first, but soon enough caught the attention of... View Details
      Keywords: Competitive Strategy; Competitive Advantage; Competition; Market Entry and Exit; Emerging Markets; Business Startups; Corporate Entrepreneurship; Product Positioning; Disruption; Disruptive Innovation; Advertising; Advertising Campaigns; Social Media; Forecasting and Prediction; Crisis Management; Growth and Development Strategy; Brands and Branding; Product Development; Production; Service Delivery; Business Growth and Maturation; Financial Statements; Cost Management; Analysis; Quality; Performance Consistency; Customer Satisfaction; Profit; Family Ownership; Food and Beverage Industry; Middle East; Saudi Arabia
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      Casadesus-Masanell, Ramon, and Fares Khrais. "Maestro Pizza: Coming in Hot!" Harvard Business School Case 722-399, May 2022.
      • May 2022
      • Case

      Deborah Quazzo at GSV Ventures

      By: William A. Sahlman, Michael D. Smith and Nicole Tempest Keller
      As COVID-19 swept across the globe in 2020, the education sector faced unprecedented disruption. Schools and colleges worldwide shut down, forcing over a billion students and teachers to move to online learning. Investor interest in the EdTech space exploded as... View Details
      Keywords: Edtech; Technology; Online Learning; COVID-19 Pandemic; Education; Information Technology; Venture Capital; Change Management; Strategy; Education Industry; Financial Services Industry; Chicago; California
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      Sahlman, William A., Michael D. Smith, and Nicole Tempest Keller. "Deborah Quazzo at GSV Ventures." Harvard Business School Case 822-131, May 2022.
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