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      • Faculty Publications  (246)

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      • March 2009
      • Teaching Note

      Antegren: A Beacon of Hope (TN)

      By: Joshua D. Margolis
      Teaching Note for [408025], [408026], [408027], and [408028]. View Details
      Keywords: Ethics; Corporate Social Responsibility and Impact; Decision Choices and Conditions; Crisis Management; Biotechnology Industry; Biotechnology Industry
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      Margolis, Joshua D. "Antegren: A Beacon of Hope (TN)." Harvard Business School Teaching Note 409-096, March 2009.
      • January 2009
      • Teaching Note

      Biocon: Launching a New Cancer Drug in India (TN)

      By: Sunil Gupta and Das Narayandas
      Teaching Note for [508026]. View Details
      Keywords: Product Launch; Market Timing; Price; Distribution Channels; Marketing Strategy; Health Care and Treatment; Biotechnology Industry; Biotechnology Industry; India
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      Gupta, Sunil, and Das Narayandas. "Biocon: Launching a New Cancer Drug in India (TN)." Harvard Business School Teaching Note 509-039, January 2009.
      • December 2008 (Revised January 2011)
      • Case

      Arcadia Biosciences: Seeds of Change

      By: Arthur A. Daemmrich, Forest L. Reinhardt and Mary Louise Shelman
      Arcadia Biosciences is an entrepreneurial California agricultural biotech company seeking to earn carbon credits by modifying commodity crops for use in China and India. Eric Rey, Arcadia's CEO, faced a strategic inflection point in early September 2008. The company... View Details
      Keywords: Business Startups; Entrepreneurship; Growth and Development Strategy; Environmental Sustainability; Science-Based Business; Climate Change; Biotechnology Industry; Biotechnology Industry; China; India; California
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      Daemmrich, Arthur A., Forest L. Reinhardt, and Mary Louise Shelman. "Arcadia Biosciences: Seeds of Change." Harvard Business School Case 709-019, December 2008. (Revised January 2011.)
      • September 2008
      • Teaching Note

      Chi Mei Optoelectronics (TN)

      By: Willy C. Shih
      Teaching Note for [608-123]. View Details
      Keywords: Diversification; Information Technology; Market Entry and Exit; Standards; Industry Clusters; Supply Chain; Production; Experience and Expertise; Biotechnology Industry; Biotechnology Industry; Taiwan; Asia; Korean Peninsula; China
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      Shih, Willy C. "Chi Mei Optoelectronics (TN)." Harvard Business School Teaching Note 609-040, September 2008.
      • September 2008
      • Background Note

      Background on the Technology of Molecular Diagnostics

      By: Regina E. Herzlinger and Jason Sanders
      To be used as background reading for the "EXACT Sciences Corp.: Commercializing a Diagnostic Test" and "Diagnostic Genomics" cases, HBS nos. 308-090 and 309-040. View Details
      Keywords: Health Testing and Trials; Technology; Biotechnology Industry; Biotechnology Industry
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      Herzlinger, Regina E., and Jason Sanders. "Background on the Technology of Molecular Diagnostics." Harvard Business School Background Note 309-050, September 2008.
      • September 2008 (Revised July 2012)
      • Case

      Khosla Ventures: Biofuels Strategy

      By: Joseph B. Lassiter III, William A. Sahlman and Alison Berkley Wagonfeld
      By 2008, a number of the firm's early cleantech investments were showing promise, and the companies were starting to need significantly more money to create the massive scale required in the energy sector. As Khosla thought about the hundreds of millions of dollars... View Details
      Keywords: Entrepreneurial Marketing; Entrepreneurial Finance; New Product Development; Partnerships; Entrepreneurial Management; Venture Capital; Strategy; Partners and Partnerships; Renewable Energy; Entrepreneurship; Investment Funds; Environmental Sustainability; Product Development; Biotechnology Industry; Biotechnology Industry
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      Lassiter, Joseph B., III, William A. Sahlman, and Alison Berkley Wagonfeld. "Khosla Ventures: Biofuels Strategy." Harvard Business School Case 809-004, September 2008. (Revised July 2012.)
      • June 2008
      • Case

      Gordon Williams: Clinical Research at Brigham and Women's Hospital

      By: H. Kent Bowen and Courtney Purrington
      Clinical research is a critical element of biomedical research and development. This case describes the challenges of clinical research, and its role in bringing breakthroughs to patients. Dr. Williams leads through his own research and special programs to train... View Details
      Keywords: Training; Health Care and Treatment; Success; Programs; Research and Development; Biotechnology Industry; Biotechnology Industry
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      Bowen, H. Kent, and Courtney Purrington. "Gordon Williams: Clinical Research at Brigham and Women's Hospital." Harvard Business School Case 608-168, June 2008.
      • April 2008
      • Teaching Note

      Viagen: Revolutioning the Livestock Industry (TN)

      By: David E. Bell, Mary L. Shelman and Eliot Sherman
      Teaching Note for [507021]. View Details
      Keywords: Investment; Genetics; Production; Training; Customers; Supply Chain; Business Plan; Commercialization; Information Technology; Performance Efficiency; Governing Rules, Regulations, and Reforms; Industry Structures; Biotechnology Industry; Biotechnology Industry
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      Bell, David E., Mary L. Shelman, and Eliot Sherman. "Viagen: Revolutioning the Livestock Industry (TN)." Harvard Business School Teaching Note 508-014, April 2008.
      • February 2008 (Revised August 2008)
      • Case

      EXACT Sciences Corp.: Commercializing a Diagnostic Test

      By: Regina E. Herzlinger
      This case addresses the challenges of commercializing molecular diagnostics. Along the way, it explains the technology, payment system, and the measures used to assess the value of a diagnostic test. View Details
      Keywords: Health Testing and Trials; Genetics; Science-Based Business; Commercialization; Biotechnology Industry
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      Herzlinger, Regina E. "EXACT Sciences Corp.: Commercializing a Diagnostic Test." Harvard Business School Case 308-090, February 2008. (Revised August 2008.)
      • November 2007
      • Class Lecture

      The Baby Business (FSS)

      By: Debora L. Spar
      In vitro fertilization and genetic screening are possible with the advent of biotechnology. International adoptions, surrogacy, and other approaches to family planning are on the rise. But few rules govern these measures, medical costs can be prohibitive, and... View Details
      Keywords: Governing Rules, Regulations, and Reforms; Policy; Demand and Consumers; Business and Government Relations; Business and Stakeholder Relations; Genetics; Societal Protocols; Commercialization; Biotechnology Industry; Biotechnology Industry
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      Spar, Debora L. "The Baby Business (FSS)." Harvard Business School Class Lecture 708-701, November 2007.
      • November 2007
      • Case

      Antegren: A Beacon of Hope

      By: Joshua D. Margolis, Thomas J. DeLong and Terence Heymann
      The CEO of Biogen Idec faces a set of difficult decisions regarding a promising drug for Multiple Sclerosis that is headed for early approval by the FDA. The first in a series focuses on operational decisions triggered by the drive for early approval. Sparks discussion... View Details
      Keywords: Demand and Consumers; Leadership; Ethics; Corporate Social Responsibility and Impact; Decision Choices and Conditions; Crisis Management; Health Testing and Trials; Biotechnology Industry; Biotechnology Industry
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      Margolis, Joshua D., Thomas J. DeLong, and Terence Heymann. "Antegren: A Beacon of Hope." Harvard Business School Case 408-025, November 2007.
      • September 2007 (Revised May 2009)
      • Case

      Syndexa and Technology Transfer at Harvard University

      By: Richard G. Hamermesh and David Kiron
      Gokhan Hotamisligil is a star researcher at Harvard School of Public Health who has made groundbreaking discoveries linking fat cells, inflammation, and diabetes. He now wants to form a company to commercialize these discoveries. At the same time, Isaac Kohlberg, the... View Details
      Keywords: Business Startups; Higher Education; Entrepreneurship; Innovation and Invention; Intellectual Property; Rights; Agreements and Arrangements; Science-Based Business; Commercialization; Biotechnology Industry; Biotechnology Industry
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      Hamermesh, Richard G., and David Kiron. "Syndexa and Technology Transfer at Harvard University." Harvard Business School Case 808-073, September 2007. (Revised May 2009.)
      • August 2007 (Revised November 2008)
      • Case

      Biocon: Launching a New Cancer Drug in India

      By: Sunil Gupta and Das Narayandas
      Kiran Majumdar-Shaw, the CEO of Biocon has to make product launch timing, pricing, channel, and communications mix decisions relating to the launch of BioMAb, a new cancer drug in India. View Details
      Keywords: Price; Health Care and Treatment; Marketing Strategy; Product Launch; Planning; Biotechnology Industry; Biotechnology Industry; India
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      Gupta, Sunil, and Das Narayandas. "Biocon: Launching a New Cancer Drug in India." Harvard Business School Case 508-026, August 2007. (Revised November 2008.)
      • May 2007 (Revised September 2008)
      • Case

      Biocon Limited

      By: Krishna G. Palepu and Ananth Chepuri
      Biocon Limited was facing significant pricing pressure in their cash cow business, that primarily consisted of manufacturing Active Pharmaceutical Ingredients (APIs). To combat this commoditization, Biocon's leadership had chosen an innovation-led strategy. This new... View Details
      Keywords: Globalized Firms and Management; Innovation and Management; Leading Change; Growth and Development Strategy; Risk Management; Organizational Change and Adaptation; Biotechnology Industry; India
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      Palepu, Krishna G., and Ananth Chepuri. "Biocon Limited." Harvard Business School Case 107-083, May 2007. (Revised September 2008.)
      • March 2007
      • Teaching Note

      Monsanto: Realizing Biotech Value in Brazil (TN)

      By: David E. Bell and Mary L. Shelman
      Keywords: Value; Biotechnology Industry; Biotechnology Industry; Brazil
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      Bell, David E., and Mary L. Shelman. "Monsanto: Realizing Biotech Value in Brazil (TN)." Harvard Business School Teaching Note 507-059, March 2007.
      • January 2007 (Revised January 2007)
      • Background Note

      Note on the U.S. Food and Drug Administration

      By: Robert F. Higgins, Richard G. Hamermesh and Virginia Fuller
      Describes the U.S. FDA with particular emphasis on its role in the development of new drugs, biologic products, and medical devices today. Provides context for the drug approval process by describing the FDA's history and organizational structure. View Details
      Keywords: Health; Governance Compliance; Policy; Product Development; Government and Politics; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry; United States
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      Higgins, Robert F., Richard G. Hamermesh, and Virginia Fuller. "Note on the U.S. Food and Drug Administration." Harvard Business School Background Note 807-050, January 2007. (Revised January 2007.)
      • January 2007
      • Background Note

      Note on Biotech Business Development

      By: Richard G. Hamermesh and Robert F. Higgins
      Describes the business development process in biotechnology companies. Topics covered include: participants in the licensing process and their interests, the major steps in the licensing process, the terms that are part of most agreements, and the most contentious... View Details
      Keywords: Agreements and Arrangements; Entrepreneurship; Intellectual Property; Biotechnology Industry
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      Hamermesh, Richard G., and Robert F. Higgins. "Note on Biotech Business Development." Harvard Business School Background Note 807-032, January 2007.
      • 2007
      • Chapter

      Fighting AIDS, Fighting Poverty: Customer Centric Marketing in the Generic Antiretroviral Business

      By: Rohit Deshpandé and Zoe Chance
      Keywords: Health Disorders; Poverty; Product Marketing; Customers; Biotechnology Industry; Biotechnology Industry
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      Deshpandé, Rohit, and Zoe Chance. "Fighting AIDS, Fighting Poverty: Customer Centric Marketing in the Generic Antiretroviral Business." In Business Solutions for the Global Poor: Creating Social and Economic Value, edited by V. Kasturi Rangan, John A. Quelch, Gustavo Herrero, and Brooke Barton. John Wiley & Sons, 2007.
      • December 2006 (Revised October 2007)
      • Case

      Monsanto: Realizing Biotech Value in Brazil

      By: David E. Bell and Mary L. Shelman
      In 2003, Monsanto's patented "Roundup Ready" technology was used illegally on 70-80% of the soybean area in southern Brazil. Under pressure from U.S. soybean growers, who were paying to license the technology, the firm implemented an innovative delivery-based... View Details
      Keywords: Plant-Based Agribusiness; Patents; Lawfulness; Emerging Markets; Product Development; Biotechnology Industry; Biotechnology Industry; Brazil
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      Bell, David E., and Mary L. Shelman. "Monsanto: Realizing Biotech Value in Brazil." Harvard Business School Case 507-018, December 2006. (Revised October 2007.)
      • December 2006 (Revised January 2008)
      • Case

      ViaGen: Revolutionizing the Livestock Industry

      By: David E. Bell, Reed Martin and Mary L. Shelman
      ViaGen has invested heavily to develop cloning technology for the livestock industry. Cloning has the potential to significantly improve the genetics of livestock, leading to higher quality meat, healthier animals, and more efficient production. Since 2003, the firm... View Details
      Keywords: Animal-Based Agribusiness; Business Plan; Governing Rules, Regulations, and Reforms; Marketing Communications; Industry Structures; Business and Government Relations; Genetics; Commercialization; Biotechnology Industry; Biotechnology Industry
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      Bell, David E., Reed Martin, and Mary L. Shelman. "ViaGen: Revolutionizing the Livestock Industry." Harvard Business School Case 507-021, December 2006. (Revised January 2008.)
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