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  • January 2024 (Revised April 2024)
  • Case

Target Malaria: Editing Mosquitoes through Gene Drives

By: Shikhar Ghosh and Shweta Bagai
Target Malaria, a non-profit research consortium, is exploring the application of CRISPR-Cas9 gene editing technology to combat malaria in Sub-Saharan Africa. Its approach uses gene drives, a revolutionary tool, to suppress the population of malaria-carrying... View Details
Keywords: Health Disorders; Technological Innovation; Nonprofit Organizations; Business Strategy; Genetics; Ethics; Governing Rules, Regulations, and Reforms; United States; United Kingdom; Burkina Faso; Africa
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Ghosh, Shikhar, and Shweta Bagai. "Target Malaria: Editing Mosquitoes through Gene Drives." Harvard Business School Case 824-068, January 2024. (Revised April 2024.)
  • January 2003 (Revised January 2007)
  • Case

Guide Dogs for the Blind Association

By: Allen S. Grossman, Jane Wei-Skillern and Kristin Lieb
In 2002, Guide Dogs for the Blind Association, the recognized world leader in the breeding and training of guide dogs, was in the midst of broadening its reach and providing additional mobility services. Chief Executive Geraldine Peacock was concerned that systemic... View Details
Keywords: Transition; Growth and Development Strategy; Resource Allocation; Organizational Change and Adaptation; Programs; Networks; Nonprofit Organizations; Competitive Strategy
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Grossman, Allen S., Jane Wei-Skillern, and Kristin Lieb. "Guide Dogs for the Blind Association." Harvard Business School Case 303-006, January 2003. (Revised January 2007.)
  • 04 Feb 2014
  • First Look

First Look: February 4

necessary for eliciting effort from those affecting the quality of interdependent teamwork. We consider the role of incentives versus social processes in catalyzing collaboration. We test our hypotheses using a unique data set of 260... View Details
Keywords: Sean Silverthlorne
  • 11 Sep 2012
  • First Look

First Look: September 11

economies to land politics. Dalian, benefitting from early access to foreign capital, consolidated control over urban territory through the designation of a development zone, which realigned local economic interests and introduced dual pressures for View Details
Keywords: Sean Silverthorne
  • 12 Oct 1999
  • Research & Ideas

Spirit at Work: The Search for Deeper Meaning in the Workplace

computer consulting firm specializing in e-commerce; Akal Security Company; and natural food enterprises such as the Yogi Tea Company), for which he serves as executive vice president. "Our goal is to provide products and services... View Details
Keywords: by Marguerite Rigoglioso
  • 02 Oct 2007
  • First Look

First Look: October 2, 2007

facing several acute problems: a conflict between his director of marketing and his director of field operations; a dramatic increase in prices by a key supplier; and a major strategic alliance that does not seem to be moving forward. Lapdesk is a for-profit View Details
Keywords: Martha Lagace
  • 08 Dec 2015
  • First Look

December 8, 2015

2015 Northampton, MA: Edward Elgar Publishing The Impact of Globalization on Argentina and Chile: Business Enterprises and Entrepreneurship By: Jones, G. Abstract—This book compares the effects of globalization on two Latin American... View Details
Keywords: Sean Silverthorne
  • 02 Sep 2008
  • First Look

First Look: September 3, 2008

Building on previous theories of how social activists inspire field-level change, we hypothesize that shareholder actions and regulatory threats are likely to prime firms to cooperate with shareholder requests for information disclosure.... View Details
Keywords: Sean Silverthorne
  • 03 Jan 2007
  • First Look

First Look: January 3, 2007

implications for the efficient targeting of social programs more generally. A key issue in this debate is whether higher purchase prices lead to more intensive product use and, therefore, greater health benefits. We present results from... View Details
Keywords: Sean Silverthorne
  • 19 Jun 2007
  • First Look

First Look: June 19, 2007

countries between 1985 and 2000, we find that the growth effects of FDI increase when we account for the quality of FDI. Download the paper: http://www.hbs.edu/research/pdf/07-072.pdf How Well Do Social Ratings Actually Measure Corporate... View Details
Keywords: Martha Lagace
  • 11 Mar 2014
  • First Look

First Look: March 11

evolution of multinational enterprises (MNEs) in host countries over time. We argue that a change in the policy environment in a host country presents an MNE with two sets of interrelated decisions. First, the MNE has to decide whether to... View Details
Keywords: Sean Silverthorne
  • September 2022
  • Case

HPP: Tapping the Netherlands’ Potential

By: Brian Trelstad and Idelès Kaandorp
Stichting Het Potentieel Pakken (HPP) was launched to solve a systemic problem in the Dutch Labor Market: gender inequity that was leading to a large number of women to work part-time in fields that were in desperately short supply of labor, like health care, child... View Details
Keywords: COVID-19 Pandemic; Grants; Scaling And Growth; Nonprofit Organizations; Opportunities; Gender; Income; Employment; Health Care and Treatment; Human Capital; Mission and Purpose; Motivation and Incentives; Growth and Development Strategy; Employment Industry; Health Industry; Education Industry; Consulting Industry; Europe; Netherlands
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Trelstad, Brian, and Idelès Kaandorp. "HPP: Tapping the Netherlands’ Potential." Harvard Business School Case 323-024, September 2022.
  • November 2004 (Revised September 2019)
  • Background Note

The U.S. Health Club Industry in 2004

By: John R. Wells, Gabriel Ellsworth and Benjamin Weinstock
In 2004, the $16.8 billion U.S. health club industry continued its strong record of growth. There were almost 27,000 health clubs in the United States, up from 6,700 two decades earlier, and these clubs claimed 41 million members, over 14% of the U.S. population.... View Details
Keywords: Health Clubs; Fitness; Gyms; Chain; Weight Loss; Obesity; Exercise; Personal Training; Bally Total Fitness; 24 Hour Fitness; YMCA; Gold's Gym; Curves; Franchise; Franchising; Subscription; Promotional Sales; Promotions; Fixed Costs; Body; Accrual Accounting; Revenue Recognition; Buildings and Facilities; Business Growth and Maturation; Business Model; For-Profit Firms; Trends; Customers; Demographics; Age; Income; Private Equity; Financing and Loans; Profit; Revenue; Geographic Scope; Multinational Firms and Management; Health; Nutrition; Business History; Employees; Retention; Human Capital; Working Conditions; Contracts; Business or Company Management; Goals and Objectives; Growth and Development Strategy; Markets; Demand and Consumers; Supply and Industry; Industry Growth; Industry Structures; Operations; Service Operations; Franchise Ownership; Private Ownership; Public Ownership; Problems and Challenges; Sales; Salesforce Management; Situation or Environment; Opportunities; Nonprofit Organizations; Welfare; Sports; Strategy; Business Strategy; Competition; Competitive Strategy; Consolidation; Corporate Strategy; Customization and Personalization; Expansion; Segmentation; Hardware; Health Industry; United States
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Wells, John R., Gabriel Ellsworth, and Benjamin Weinstock. "The U.S. Health Club Industry in 2004." Harvard Business School Background Note 705-445, November 2004. (Revised September 2019.)
  • August 2008 (Revised July 2009)
  • Case

Repositioning CARE USA

By: V. Kasturi Rangan and Katharine Lee
CARE USA, a large ($600 million) international nonprofit/NGO, had recently revamped its external branding and positioning in support of its international development work. The case lays out the challenges facing its new CEO, Helene Gayle, as she manages through the... View Details
Keywords: Change Management; Management; Brands and Branding; Marketing Strategy; Product Positioning; Organizational Change and Adaptation; Non-Governmental Organizations; Adaptation; United States
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Rangan, V. Kasturi, and Katharine Lee. "Repositioning CARE USA." Harvard Business School Case 509-005, August 2008. (Revised July 2009.)
  • 30 Aug 2016
  • First Look

August 30, 2016

forthcoming Journal of Marketing Research Incentives versus Reciprocity: Insights from a Field Experiment By: Chung, Doug J., and Das Narayandas Abstract—We conduct a field experiment in which we vary the sales force compensation scheme at an Asian View Details
Keywords: Carmen Nobel
  • 01 Nov 1999
  • Research & Ideas

Companies, Cultures and the Transformation to the Transnational

of doing things" and shape its international organization structure and processes. Business historian Alfred Chandler has traced the influence of the cultural values and social structures on British management practice. For reasons... View Details
Keywords: by Christopher A. Bartlett & Sumantra Ghoshal
  • 05 Mar 2013
  • First Look

First Look: March 5

http://sloanreview.mit.edu/the-magazine/2013-winter/54215/how-to-identify-the-best-customers-for-your-business/ Prolonged Thought: Proposing Type 3 Processing Authors:Dijksterhuis, Ap, Madelijn Strick, Maarten W. Bos, and Loran F. Nordgren Publication:Dual Process... View Details
Keywords: Sean Silverthorne
  • 03 Sep 2013
  • First Look

First Look: September 3

context. Publisher's link: http://papers.ssrn.com/sol3/papers.cfm?abstract_id=1865878 August 2013 Business Ethics. 2d ed., edited by Michael Boylan. Hoboken, N.J.: John Wiley & Sons, 2013 Multinational Enterprises and Incomplete... View Details
Keywords: Sean Silverthorne
  • 15 Oct 2008
  • First Look

First Look: October 15, 2008

Mouse and the Wealthy Elephant Live Happily Ever After? Authors:James E. Austin and Herman B. Leonard Abstract What happens when small iconic socially oriented businesses are acquired by large corporations? Such mergers create significant... View Details
Keywords: Martha Lagace
  • 04 Oct 2011
  • First Look

First Look: October 4

knowing "who we are" might depend in part on repeatedly remembering to forget "who we were not." The Enabling Role of Social Position in Diverging from the Institutional Status Quo: Evidence from the U.K. National... View Details
Keywords: Sean Silverthorne
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