Publications
Publications
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- All HBS Web
(1,201)
- Faculty Publications (280)
- 2024
- Working Paper
Tamoxifen—Reducing Breast Cancer Risks: Case Histories of Transformational Advances
By: Amar Bhidé, Srikant Datar and Katherine Stebbins
We describe the development of tamoxifen, considered a “gold standard” treatment for
millions of breast cancer patients. Specifically, we describe breast cancer treatments before tamoxifen’s
development; the initial development of tamoxifen from 1960 to 1973;... View Details
- June 2020 (Revised January 2024)
- Case
TraceTogether
By: Mitchell B. Weiss and Sarah Mehta
By April 7, 2020, over 1.4 million people worldwide had contracted the novel coronavirus (COVID-19). Governments raced to curb the spread of COVID-19 by scaling up testing, quarantining those infected, and tracing their possible contacts. It had taken Singapore’s... View Details
Keywords: COVID-19; Contact Tracing; Government Administration; Crisis Management; Health; Health Pandemics; Innovation and Invention; Innovation Leadership; Innovation Strategy; Technological Innovation; Social Issues; Information Technology; Mobile and Wireless Technology; Applications and Software; Technology Adoption; Health Industry; Public Administration Industry; Singapore
- March 2020
- Case
Voi Technology
By: Jeffrey F. Rayport and Olivia Hull
Voi Technology, a fast-growing start-up out of Sweden, is competing in the highly contested European e-scooter sharing market. With a presence in nearly 40 cities in Europe by February 2020, the firm is working hard to improve its unit economics to reach profitability.... View Details
Keywords: Entrepreneurship; Business Strategy; Technology Adoption; Innovation Strategy; Technological Innovation; Marketing Strategy; Business Plan; Product Marketing; Product Launch; Product Positioning; Energy Conservation; Cross-Cultural and Cross-Border Issues; Global Strategy; Globalized Economies and Regions; Innovation Leadership; Human Capital; Laws and Statutes; Growth Management; Operations; Logistics; Service Operations; Supply Chain Management; Organizational Culture; Information Infrastructure; Transportation; Transportation Industry; Technology Industry; Europe
- 2020
- Working Paper
The Effects of Hierarchy on Learning and Performance in Business Experimentation
By: Sourobh Ghosh, Stefan Thomke and Hazjier Pourkhalkhali
Do senior managers help or hurt business experiments? Despite the widespread adoption of business experiments to guide strategic decision-making, we lack a scholarly understanding of what role senior managers play in firm experimentation. Using proprietary data of live... View Details
- February 2020 (Revised March 2020)
- Case
Prime Coalition: Catalytic Capital for Climate Innovation
By: Ramana Nanda, Benjamin N. Roth and Olivia Hull
With long development timelines and high risk, new energy technologies were often left to languish in the “valley of death,” unable to raise enough funds to bring a product to market. In 2014, Sarah Kearney founded the nonprofit Prime Coalition to solve this problem.... View Details
Keywords: Energy Conservation; Renewable Energy; Social Entrepreneurship; Venture Capital; Investment; Innovation and Invention; Technological Innovation; Mission and Purpose; Science-Based Business; Nonprofit Organizations; Social Enterprise; Energy Industry; Technology Industry; Green Technology Industry; United States
- January 2020
- Case
SK Group: Social Progress Credits
By: George Serafeim, Ethan Rouen and David Freiberg
SK Group was one of the largest companies South Korea. A family-run conglomerate consisting of around 120 subsidiaries and employing more than 100,000, SK was tightly knit into the fabric of Korean society. SK viewed their future success as contingent upon the strength... View Details
Keywords: Impact; Impact Investing; Impact Measurement; Social Value; Social Development; Conglomerates; Measurement Of Purpose; ESG; ESG (Environmental, Social, Governance) Performance; Capital Markets; Innovation; Environmental Impact; Collaboration; Social Enterprise; Social and Collaborative Networks; Social Issues; Measurement and Metrics; Value Creation; Cooperation; Environmental Sustainability; Employment; Accounting; Energy Industry; Telecommunications Industry; Chemical Industry; South Korea
- January 2020
- Article
Jack of All Trades and Master of Knowledge: The Role of Diversification in New Distant Knowledge Integration
By: Frank Nagle and Florenta Teodoridis
We consider the role of individual-level diversification as a mechanism through which skilled researchers engage in successful exploration—recognizing and integrating new knowledge external to one’s domains of expertise. To approach an ideal experiment, we (1) employ a... View Details
- 2019
- Article
Overcoming Cultural Resistance to Open Source Innovation
By: John Winsor, Jin Hyun Paik, Michael Tushman and Karim R. Lakhani
Purpose: This article offers insight on how to effectively help incumbent organizations prepare for global business shifts to open source and digital business models.
Design/methodology/approach: Discussion related to observation, experience and case studies... View Details
Design/methodology/approach: Discussion related to observation, experience and case studies... View Details
- November 2019 (Revised May 2020)
- Case
Collibra
By: Lynda M. Applegate, Jeffrey F. Rayport and Julia Kelley
Founded in 2008 at Vrije Universiteit Brussels, Collibra was a data intelligence company that found product-market fit in the years after the global financial crisis when many companies were under pressure from consumers and governments to improve their data management... View Details
Keywords: Entrepreneurship; Governance; Innovation and Invention; Technological Innovation; Markets; Information Technology; Applications and Software; Technology Adoption; Digital Platforms; Internet and the Web; Customer Focus and Relationships; Customer Satisfaction; Expansion; Information Technology Industry; Technology Industry; Europe; Belgium; Brussels; North and Central America; United States; New York (city, NY); New York (state, US)
- November 2019
- Case
DeepMap: Charting the Road Ahead for Autonomous Vehicles
By: Shane Greenstein and Nicole Tempest Keller
Founded in 2016, DeepMap developed high definition (HD) mapping software and localization services for Level 4+ autonomous vehicles. Traditional navigational maps were accurate to a few meters, which was sufficient for drivers but not for machine-driven vehicles that... View Details
- September 2019
- Teaching Note
Gun Safety in America: Three Leaders Propose Innovative Solutions
By: Rosabeth Moss Kanter and Joseph Paul
This is a teaching note to the original case: Gun violence was a significant problem in America. Three Harvard Advanced Leadership Initiative Fellows Christy Wood, Russell Sternlicht, and Gareth Glaser each decided to do something about gun safety. They each used... View Details
Keywords: Gun Violence; Guns; Advanced Leadership; Advanced Leadership Initiative; Innovation; Innovation ＆ Entrepreneurship; Social Change; Social Responsibility; Leadership; Change Management; Experience and Expertise; Social Entrepreneurship; Values and Beliefs; Policy; Governing Rules, Regulations, and Reforms; Leading Change; Non-Governmental Organizations; Social Issues; Corporate Social Responsibility and Impact; United States
- September 2019 (Revised January 2020)
- Case
Gun Safety in America: Three Leaders Propose Innovative Solutions
By: Rosabeth Moss Kanter and Joseph Paul
Gun violence was a significant problem in America. Three Harvard Advanced Leadership Initiative Fellows Christy Wood, Russell Sternlicht, and Gareth Glaser each decided to do something about gun safety. They each used their professional and leadership experience to... View Details
Keywords: Gun Violence; Guns; Advanced Leadership; Advanced Leadership Initiative; Innovation; Innovation ＆ Entrepreneurship; Social Change; Social Responsibility; Leadership; Change Management; Experience and Expertise; Social Entrepreneurship; Values and Beliefs; Policy; Governing Rules, Regulations, and Reforms; Leading Change; Non-Governmental Organizations; Social Issues; Innovation and Invention; Corporate Social Responsibility and Impact; United States
- 2024
- Working Paper
Coronary Artery Bypass Grafting—Impossible to Routine: Case Histories of Transformational Advances
By: Amar Bhidé, Srikant M. Datar and Fabio Villa
We describe how Coronary Artery Bypass Grafting (CABG, or more popularly, “bypass”) operations
revolutionized the treatment of coronary disease (that can produce fatal heart attacks and debilitating
angina). Specifically, we chronicle the: 1) development of the... View Details
- 2024
- Working Paper
Antibiotic Treatments for Ulcers--Eradicating H-Pylori Infections: Case Histories of Transformational Advances
By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins
This case history describes how a chance discovery of bacteria that infect stomach linings completely changed how physicians treat ulcers. Specifically, we chronicle how: 1) two Australian physicians brought the bacterial infection to the world’s attention and... View Details
- 2024
- Working Paper
Computed Tomography (CT)--Beyond Traditional X-Rays: Case Histories of Transformational Advances
By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins
This case history describes how Computed Tomography (CT) scanners - that combine Xrays
and computers to image soft tissues of the brain and other organs -- have become a widely used
diagnostic tool. Specifically, we chronicle the 1) initial development of CT... View Details
- 2024
- Working Paper
Gastrointestinal Endoscopy--Without Cutting In: Case Histories of Transformational Advances
By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins
This case history describes how endoscopy transformed the diagnosis of ulcers, cancerous polyps, and other alimentary canal diseases and enabled “minimally invasive” surgeries to treat such diseases. Specifically, we chronicle how: 1) flexible glass fiber endoscopes... View Details
- 2024
- Working Paper
HIV Tests and AIDS Treatments—Containing a Fearsome Pandemic: Case Histories of Transformational Advances
By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins
This case history describes how a diverse cast of characters, including public health organizations, research laboratories, for-profit healthcare companies, activists, and regulators, rolled back the outbreak of HIV/AIDS in just fifteen years. Moreover, as the case... View Details
- 2024
- Working Paper
Laparoscopy—Minimally Invasive Surgery: Case Histories of Transformational Advances
By: Amar Bhidé, Caitlin N. Bowler and Srikant M. Datar
We describe how operations through laparoscopes – tubular instruments inserted into abdominal cavities – revolutionized gynecological and other surgeries inside the abdomen, such as gall bladder removal. Specifically, we chronicle the 1) foundational contributions of... View Details
- 2024
- Working Paper
Magnetic Resonance Imaging—High Quality and Radiation Free: Case Histories of Transformational Advances
By: Srikant M. Datar, Amar Bhidé and Katherine Stebbins
This case history describes how Magnetic Resource Imaging (MRI) came to complement – and partially replace -- computed tomography (CT) imaging of soft tissue. Specifically, we chronicle 1) the development of foundational techniques and prototypes (through the 1970s);... View Details
- 2024
- Working Paper
Mammography - Early Detection, Precise Diagnoses: Case Histories of Transformational Advances
By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins
This case history describes how the development of x-ray-based techniques and equipment (“mammography”) led to widespread screening for breast cancer and enabled “minimally invasive” biopsies of breast tumors. Specifically, we chronicle how: 1) new protocols and... View Details