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April 1993 (Revised October 1995)
Case

ALZA and Bio-Electro Systems (A): Technological and Financial Innovation

By: Josh Lerner and Peter Tufano

To develop the next generation of risky products, ALZA, a mature and profitable biotechnology firm specializing in drug delivery systems, must raise $40 million. Organizational constraints and competitive concerns demand that the work be done inside the firm. However,... View Details

Keywords: Risk and Uncertainty; Technological Innovation; Business Subsidiaries; Decision Choices and Conditions; Corporate Finance; Medical Devices and Supplies Industry; Medical Devices and Supplies Industry

October 2016 (Revised November 2016)
Case

Innovating Beyond Ochsner

By: Richard G. Hamermesh and Olivia Hull

The Ochsner Health System has developed a proprietary software tool designed to treat hypertension. Built into the system’s electronic medical records, the Hypertension Digital Medicine program allows patients to record their blood pressure at home and share readings... View Details

September 2013 (Revised October 2016)
Background Note

A Note on Healthcare IT and Applications to the Healthcare Industry

By: Robert F. Higgins and Diana Maichin

This note provides an overview of three key healthcare IT areas: electronic medical records and electronic health records, revenue cycle management, and telemedicine. This note also contains a glossary of key terms and acronyms in this space as well as exhibits... View Details

Keywords: Health Care; Health Care Industry; Healthcare IT; Healthcare; Healthcare Technology; Healthcare Ventures; Electronic Medical Records; Electronic Health Records; Revenue Cycle Management; Telemedicine; Health; Health Care and Treatment; Information Technology; Information Management; Information Technology Industry; Information Technology Industry; United States

May 2021
Article

Risk-Mitigating Technologies: The Case of Radiation Diagnostic Devices

By: Alberto Galasso and Hong Luo

We study the impact of consumers’ risk perception on firm innovation. Our analysis exploits a major surge in the perceived risk of radiation diagnostic devices following extensive media coverage of a set of over-radiation accidents involving CT scanners in late 2009.... View Details

Keywords: Risk Perception; Innovation; Medical Devices; Liability Risk; Risk and Uncertainty; Perception; Technological Innovation

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November 2016 (Revised November 2016)
Case

Radial Analytics Probes Post-Acute Care

By: Richard G. Hamermesh and Olivia Hull

Thaddeus Fulford-Jones and Eric Weiss, founders of healthcare technology startup Radial Analytics, have been busy developing a software program designed to save hospitals money and improve patient outcomes by producing customized care plans for patients leaving the... View Details

Keywords: Electronic Medical Records; Electronic Health Records; Data Science; Entrepreneurship; Health Care and Treatment; Business Model; Business Startups; Innovation and Invention; Growth Management; Marketing Strategy; Product Launch; Product Positioning; Science-Based Business; Business Strategy; Technology Industry; Technology Industry; Cambridge; Massachusetts

October 2013 (Revised January 2014)
Supplement

Fred Khosravi and AccessClosure (B)

By: Richard G. Hamermesh and Lauren Barley

It was January 2013, and Fred Khosravi, chairman of the board of AccessClosure Inc., wondered what the new year had in store for him and AccessClosure, the company he founded in late 2002. Khosravi was cautiously optimistic—the Mountain View, California-based medical... View Details

Keywords: Medical Devices; Vascular Closure Device; Patent Litigation; Patenting; Biomedical Research; Biotechnology; Biotech; Technological Innovation; Patents; Health Care and Treatment; Biotechnology Industry; United States; California

Research Summary

Overview

Patient Portals: The Provider Role
Patient portals are widespread, but evidence of impact is limited. In this study, we use a large dataset spanning 2 years and >1 million patients across 650 primary care practices to explore the "other side" of portals: health... View Details

Keywords: Healthcare Technology; Electronic Health Records; Health Care Delivery

October 2012 (Revised October 2013)
Case

Rock Health

By: Robert F. Higgins and Ian McKown Cornell

Rock Health was a San Francisco–based nonprofit organization offering accelerator services to spur innovation at the intersection of healthcare and technology. The company was the creation of Halle Tecco (HBS '11) and her HBS classmate Nate Gross (HBS '11), who met... View Details

Keywords: Innovation; Incubation; Healthcare Technology; Startups; Entrepreneurship; Innovation and Management; Health Care and Treatment; Business Startups; Health Industry; San Francisco; California; United States

August 3, 2022
Article

How Will Amazon Approach U.S. Primary Care?

By: Robert S. Huckman and Bradley Staats

Amazon has a playbook for reinventing businesses that it enters. It includes simplifying processes, experimenting to determine which new approaches work best, and continuously recombining its existing assets to come up with a better way to do things. It is likely to... View Details

Keywords: Amazon; Health Care; Technology; Primary Care; Health Care and Treatment; Information Infrastructure; Technology Industry; Technology Industry; United States

November 2022 (Revised April 2024)
Case

Martine Rothblatt and United Therapeutics: A Series of Implausible Dreams

By: Debora L. Spar and Julia M. Comeau

In 1990, satellite expert and Sirius XM founder Martine Rothblatt was determined to save the life of her seven-year-old daughter, Jenesis, who was diagnosed with a terminal illness called Pulmonary Arterial Hypertension (PAH). At the time, there was little medication... View Details

Keywords: Pharmaceutical Companies; Technological And Scientific Innovation; Organ Donation; Health Care and Treatment; Health Disorders; Innovation and Invention; Medical Devices and Supplies Industry; Medical Devices and Supplies Industry; United States; District of Columbia

November 2024
Teaching Note

Martine Rothblatt and United Therapeutics: A Series of Implausible Dreams

By: Debora L. Spar and Julia M. Comeau

Teaching Note for HBS Case No. 323-039. In 1990, satellite expert and Sirius XM founder Martine Rothblatt was determined to save the life of her seven-year-old daughter, Jenesis, who was diagnosed with a terminal illness called Pulmonary Arterial Hypertension (PAH). At... View Details

Keywords: Pharmaceutical Companies; Technological And Scientific Innovation; Organ Donation; Health Care and Treatment; Health Disorders; Innovation and Invention; Medical Devices and Supplies Industry; Medical Devices and Supplies Industry; United States; District of Columbia

March 2015
Case

Twine Health

By: Robert S. Huckman, Ariel D. Stern and Matthew G. Preble

In late 2014, Dr. John Moore (CEO), Frank Moss (chairman), and Scott Gilroy (CTO) of Twine Health (Twine) had to resolve several challenges that threatened to restrict the widespread dissemination of its sole product, Twine. Twine was a cloud-based platform that... View Details

Keywords: Health Care; Chronic Disease; Technology Adoption; Digital Health; Health Acceleration Challenge; Strategy; Disease Management; Health; Health Care and Treatment; Information Technology; Mobile and Wireless Technology; Health Industry; United States; Massachusetts

Research Summary

Overview

We are studying the practical application of Michael Porter's value-based strategy to reform health care by examining best practices of integrated practice units, outcome measurement, cost measurement, value-based payment, episode based payment, regionalization of... View Details

Keywords: Health Care; Health Care Outcomes; Healthcare IT; Health Care Quality; Health Economics; Value Agenda; Information Technology; Mobile App; Big Data; Electronic Health Records; Pers; Value Creation; Information Technology Industry; United States

February 2021 (Revised June 2021)
Case

Brainlab: Imaging a MedTech Future

By: Regina E. Herzlinger, Gregory P. Licholai and Federica Gabrieli

Can Brainlab, a privately held firm, compete with giants like Medtronic and Amazon in delivering the Digital Operating Room of the future? The CEO is pondering solutions for secure exchange of medical information, pricing a new robotic imaging device, and reorganizing... View Details

January 2014
Supplement

Fred Khosravi and AccessClosure (C)

By: Richard Hamermesh and Lauren Barley

On September 11, 2013, the three-judge panel of the U.S. Court of Appeals for the Federal Circuit denied St. Jude's request to rehear an appeal on the "double patenting" ruling for the '439 patent. Further, it removed the injunction threat that was hanging over the... View Details

Keywords: Medical Devices; Vascular Closure Device; Patent Litigation; Patenting; Biomedical Research; Biotechnology; Biotech; Technological Innovation; Patents; Health Care and Treatment; Biotechnology Industry; United States

Teaching Interest

Overview

By: Regina E. Herzlinger

Course Requirements

Students are required to prepare a business plan, which employs the framework of this course, to explore an entrepreneurial opportunity in health care, and to evaluate their classmates' plans.

Career Focus

For... View Details

Keywords: Healthcare; Healthcare Industry; Healthcare Innovation; Healthcare Costs; Healthcare Operations; Healthcare Organizations; Healthcare Startups; Healthcare Technology; Healthcare Ventures

Article

One Obstacle to Curing Cancer: Patient Data Isn't Shared

By: Richard G. Hamermesh and Kathy Giusti

Precision Medicine requires large datasets to identify the mutations that lead to various cancers. Currently, genomic information is hoarded in fragmented silos within numerous academic medical centers, pharmaceutical companies, and some disease-based foundations. For... View Details

Keywords: Healthcare; Technological And Scientific Innovation; Cancer Care In The U.S.; Cancer Treatment; Precision Medicine; Personalized Medicine; Data Sharing; Technological Innovation; Analytics and Data Science; Health Disorders; Medical Specialties; Research and Development; Customization and Personalization; Health Industry; United States

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September 2013
Case

Advanced Leadership Pathways: General Gale Pollock and Services for the Vision Impaired

By: Rosabeth Moss Kanter, Juliane Calingo Schwetz and Patricia Bissett Higgins

In July 2012, retired United States Army Major General Gale Pollock created Elevivo, a venture that worked on developing a comprehensive disease management software system to support the growing number of visually impaired individuals by providing them with tailored... View Details

Keywords: United States; Health Care; Health Care Education; Insurance Companies; Disease Management; Technology; Military; Leadership Skills; Health; Health Care and Treatment; Education; Insurance; Information Technology; Entrepreneurship; Leadership; Information Technology Industry; Information Technology Industry; United States

06 Jan 2016
Cold Call Podcast

A Microchip in Your Medicine

Keywords: Re: Richard G. Hamermesh

April 2014 (Revised March 2015)
Case

GE and the Industrial Internet

By: Karim R. Lakhani, Marco Iansiti and Kerry Herman

CEO Jeff Immelt considers whether GE is moving fast enough on its new Industrial Internet initiative. The undertaking includes building out an Industrial Internet, connecting machines and devices, collecting their data and operations, and providing services to clients... View Details

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