Publications

2017
Mimeo

Science for Society: Science and Technology Based Social Entrepreneurship

By: Tarun Khanna, Shashank Shah and Kundan Madireddy

This publication is an outcome of the team's research, engagement and interactions with over 25 science and technology-based social enterprises in India. It provides details on the research process, insightful outcomes and innovative impact.
Throughout the... View Details

Keywords: Social Entrepreneurship; Science-Based Business; Information Technology; Business and Community Relations; India

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February 2016 (Revised September 2017)
Case

Neurotrack and the Alzheimer's Puzzle

By: Richard G. Hamermesh, Liz Kind and Carin-Isabel Knoop

Elli Kaplan founded Neurotrack in 2012 with a breakthrough noninvasive cognitive diagnostics test that will detect Alzheimer's disease in its earliest pre-symptomatic stages. While the company has gained great traction in the three years since it was started, with no... View Details

Keywords: Alzheimer's Disease; Diagnostics; Healthcare; Entrepreneurship; Health Disorders; Science-Based Business; Business Model; Medical Devices and Supplies Industry; United States

2001
Chapter

Transforming Life, Transforming Business: The Life Science Revolution

By: Juan Enriquez and Ray A. Goldberg

Keywords: Science-Based Business; Organizational Change and Adaptation; Human Needs; Welfare; Transformation

11 Nov 2015
Working Paper Summaries

Public R&D Investments and Private-sector Patenting: Evidence from NIH Funding Rules

Keywords: by Danielle Li; Health; Biotechnology; Pharmaceutical; Medical Devices & Supplies

1992
Chapter

Issues of Participation and Rights Allocation in Tradeable Permits Systems to Reduce Greenhouse Gas Emissions

By: James K. Sebenius and Michael Grubb

Keywords: Corporate Social Responsibility and Impact; Climate Change; Pollutants; Science-Based Business

1999
Chapter

The Pharmaceutical Industry and the Revolution in Molecular Biology: Interactions Among Scientific, Institutional, and Organizational Change

By: Rebecca Henderson, Gary P. Pisano and Luigi Orsenigo

Keywords: Science-Based Business; Organizational Change and Adaptation; Transformation; Pharmaceutical Industry

September 2024
Case

Myeloma Investment Fund

By: Kyle Myers and Scott Sawaya

This case explores a critical decision facing the Myeloma Investment Fund (MIF) as it evaluates two investment opportunities aimed at accelerating a cure for multiple myeloma.

The MIF, a venture philanthropy fund, must choose between two distinct paths. One... View Details

Keywords: Venture Philanthropy; Biomedical Research; Investing For Impact; Innovation ＆ Entrepreneurship; Venture Capital; Science-Based Business; Philanthropy and Charitable Giving; Decision Making; Health Care and Treatment; Biotechnology Industry; Pharmaceutical Industry

August 2024 (Revised November 2024)
Case

Commonwealth Fusion Systems: Born at Scale

By: Joshua Lev Krieger, Jim Matheson, Kyle Myers, Gunnar Trumbull and Richard Vietor

This case study chronicles the journey of Commonwealth Fusion Systems (CFS) on its ambitious mission to commercialize fusion energy and become the world’s leading provider of fusion power plants. Emerging from a “special arrangement” with MIT's Plasma Science and... View Details

Keywords: Nuclear Energy; Innovation; Entrepreneurship; Entrepreneurial Finance; Energy Generation; Commercialization; Science-Based Business; Technological Innovation; Market Entry and Exit; Energy Industry

January 2011 (Revised July 2012)
Case

Arcadia Biosciences: Seeds of Change (Abridged)

By: Arthur A. Daemmrich

Arcadia Biosciences is seeking to introduce genetically modified rice to China that will lower farmers' costs and generate environmental benefits through reduced greenhouse gas emissions. The case describes challenges facing this small agricultural biotechnology... View Details

Keywords: Plant-Based Agribusiness; Intellectual Property; Genetics; Environmental Sustainability; Science-Based Business; Climate Change; Agriculture and Agribusiness Industry; Biotechnology Industry; China

2015
Case

Advanced Leadership Pathways: Torsten Thiele and the Global Ocean Trust

By: Rosabeth Moss Kanter and Brian Hoffstein

Following a successful career in finance, Torsten Thiele devoted himself full-time to the challenging cause of ocean conservation and stewardship. In August 2015, Thiele had already come a long way in spearheading initiatives towards the protection of the ocean: from... View Details

Keywords: Environment; Natural Environment; Environmental Sustainability; Pollutants; Science-Based Business; Climate Change; Social Enterprise; Leadership

November 2021 (Revised May 2022)
Case

QuantumScape's Mission to Revolutionize Energy Storage for a Sustainable Future

By: William A. Sahlman, Allison M. Ciechanover and Jeff Huizinga

QuantumScape CEO Jagdeep Singh juggles the many activities required to lead the next-generation battery pioneer. Founded in 2010, QuantumScape’s mission was to develop new “solid-state” car batteries that would improve upon traditional lithium-ion batteries in key... View Details

Keywords: Batteries; Electric Vehicles; SPACs; Innovation and Management; Technological Innovation; Science-Based Business; Environmental Sustainability; Auto Industry; Energy Industry; California; San Jose

February 2008 (Revised August 2008)
Case

EXACT Sciences Corp.: Commercializing a Diagnostic Test

By: Regina E. Herzlinger

This case addresses the challenges of commercializing molecular diagnostics. Along the way, it explains the technology, payment system, and the measures used to assess the value of a diagnostic test. View Details

Keywords: Health Testing and Trials; Genetics; Science-Based Business; Commercialization; Biotechnology Industry

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01 Mar 2005
News

Campaign Passes Goal, Continues

organizations and communities they join. “What we do here has a deep and broad impact on society as a whole. The School really is a pioneer. Just look at our current research in entrepreneurship and social enterprise, and our new initiatives in health care, education... View Details

Keywords: Colleges, Universities, and Professional Schools; Educational Services; Religious, Grantmaking, Civic, Professional, and Similar Organizations; Personal Services

December 2009 (Revised April 2012)
Case

Neoprene

By: Tom Nicholas and Felipe Tamega Fernandes

In 1931, during one of the worst economic crises in U.S. history, Du Pont announced the discovery of an innovative rubber synthetic product—neoprene. Yet at the time of the announcement, Du Pont did not have any neoprene to sell. Manufacturing facilities were still... View Details

Keywords: Financial Crisis; Business History; Innovation and Invention; Product Development; Risk and Uncertainty; Science-Based Business; Commercialization; Chemical Industry; United States

22 Apr 2008
First Look

First Look: April 22, 2008

financial success had happened on the expense of the informal and relational atmosphere that used to characterize the company. But did it matter, Otano wondered? How should he go forward? Purchase this case:... View Details

Keywords: Martha Lagace

December 2023 (Revised March 2024)
Case

Manufacturing Moderna's Future

By: Satish Tadikonda and William Marks

In 2019, Moderna faced long odds of survival having failed to develop a successful clinical program out of the vast platform technology they had built around mRNA. Nearly overnight, the company skyrocketed to success with a vaccine for COVID-19, leading to an extremely... View Details

Keywords: Health Pandemics; Health Testing and Trials; Technological Innovation; Product Development; Production; Science-Based Business; Biotechnology Industry

December 2008 (Revised January 2011)
Case

Arcadia Biosciences: Seeds of Change

By: Arthur A. Daemmrich, Forest L. Reinhardt and Mary Louise Shelman

Arcadia Biosciences is an entrepreneurial California agricultural biotech company seeking to earn carbon credits by modifying commodity crops for use in China and India. Eric Rey, Arcadia's CEO, faced a strategic inflection point in early September 2008. The company... View Details

Keywords: Business Startups; Entrepreneurship; Growth and Development Strategy; Environmental Sustainability; Science-Based Business; Climate Change; Agriculture and Agribusiness Industry; Biotechnology Industry; China; India; California

2008
Article

The Gordon Research Conferences As Scientific Infrastructure

By: Arthur A. Daemmrich and Leah Shaper

Conferences serve as a crucial part of scientific infrastructure by offering participants the opportunity to announce novel findings, discuss research methods, and take part in a variety of networking activities. Presenting papers and learning about unpublished new... View Details

Keywords: Conferences; Interpersonal Communication; Infrastructure; Science-Based Business; Social and Collaborative Networks

February 2005 (Revised November 2006)
Case

InfoVision (A): Technology Transfer at Georgia Tech

InfoVision illustrates university technology transfer through the choices of a graduating doctoral student. Also explores the challenges of working across the scientific, business, and legal disciplines in the Georgia Tech transfer program. View Details

Keywords: Information Technology; Problems and Challenges; Transformation; Higher Education; Science-Based Business; Commercialization; Research and Development; Education Industry; Georgia (state, US)