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      • May 2022
      • Article

      Strengthening Digital Infrastructure: A Policy Agenda for Free and Open Source Software

      By: Frank Nagle
      While there is little debate that digital forces are playing an increasingly crucial role in the economy, there is limited understanding of the importance of the digital infrastructure that underlies this role. Much of the discussion around digital infrastructure has... View Details
      Keywords: Open Source; Applications and Software; Policy; Infrastructure; Open Source Distribution
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      Nagle, Frank. "Strengthening Digital Infrastructure: A Policy Agenda for Free and Open Source Software." Brookings Series: Reimagining Modern-day Markets and Regulations (May 2022).
      • 2022
      • Working Paper

      Causal Inference During A Pandemic: Evidence on the Effectiveness of Nebulized Ibuprofen as an Unproven Treatment for COVID-19 in Argentina

      By: Sebastian Calonico, Rafael Di Tella and Juan Cruz Lopez Del Valle
      Many medical decisions during the pandemic were made without the support of causal evidence obtained in clinical trials. We study the case of nebulized ibuprofen (NaIHS), a drug that was extensively used on COVID-19 patients in Argentina amidst wild claims about its... View Details
      Keywords: COVID-19; Drug Treatment; Health Pandemics; Health Care and Treatment; Decision Making; Outcome or Result; Argentina
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      Calonico, Sebastian, Rafael Di Tella, and Juan Cruz Lopez Del Valle. "Causal Inference During A Pandemic: Evidence on the Effectiveness of Nebulized Ibuprofen as an Unproven Treatment for COVID-19 in Argentina." NBER Working Paper Series, No. 30084, May 2022.
      • May 2022
      • Article

      Coins for Bombs: The Predictive Ability of On-Chain Transfers for Terrorist Attacks

      By: Dan Amiram, Evgeny Lyandres and Daniel Rabetti
      This study examines whether we can learn from the behavior of blockchain-based transfers to predict the financing of terrorist attacks. We exploit blockchain transaction transparency to map millions of transfers for hundreds of large on-chain service providers. The... View Details
      Keywords: Blockchain; Bitcoin; Accounting; AI and Machine Learning; National Security; Governing Rules, Regulations, and Reforms
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      Amiram, Dan, Evgeny Lyandres, and Daniel Rabetti. "Coins for Bombs: The Predictive Ability of On-Chain Transfers for Terrorist Attacks." Journal of Accounting Research 60, no. 2 (May 2022): 427–466.
      • April 12, 2022
      • Article

      Evaluation of Individual and Ensemble Probabilistic Forecasts of COVID-19 Mortality in the United States

      By: Estee Y. Cramer, Evan L. Ray, Velma K. Lopez, Johannes Bracher, Andrea Brennen, Alvaro J. Castro Rivadeneira, Michael Lingzhi Li and et al.
      Short-term probabilistic forecasts of the trajectory of the COVID-19 pandemic in the United States have served as a visible and important communication channel between the scientific modeling community and both the general public and decision-makers. Forecasting models... View Details
      Keywords: COVID-19; Forecasting and Prediction; Health Pandemics; Mathematical Methods; Partners and Partnerships
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      Cramer, Estee Y., Evan L. Ray, Velma K. Lopez, Johannes Bracher, Andrea Brennen, Alvaro J. Castro Rivadeneira, Michael Lingzhi Li, and et al. "Evaluation of Individual and Ensemble Probabilistic Forecasts of COVID-19 Mortality in the United States." e2113561119. Proceedings of the National Academy of Sciences 119, no. 15 (April 12, 2022). (See full author list here.)
      • March 2022 (Revised March 2024)
      • Case

      DaVita Responds to COVID

      By: Susanna Gallani and David Lane
      Early in August 2021, DaVita CEO Javier Rodriguez was assessing the ongoing impact of the COVID-19 pandemic on his firm, which provided life-sustaining kidney dialysis to roughly 240,000 people. Effective infection control practices and information sharing had ensured... View Details
      Keywords: COVID-19 Pandemic; Change Management; Communication; Talent and Talent Management; Fairness; Values and Beliefs; Corporate Accountability; Health Care and Treatment; Health Pandemics; Human Resources; Employee Relationship Management; Retention; Wages; Working Conditions; Leadership Style; Crisis Management; Organizational Culture; Health Industry; United States
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      Gallani, Susanna, and David Lane. "DaVita Responds to COVID." Harvard Business School Case 122-007, March 2022. (Revised March 2024.)
      • March 2022
      • Article

      Assessing the Impact of the COVID-19 Pandemic on Clinician Ambulatory Electronic Health Record Use

      By: A Jay Holmgren, Lance Downing, Mitchell Tang, Christopher Sharp, Christopher Longhurst and Robert S. Huckman
      Objective: The COVID-19 pandemic changed clinician electronic health record (EHR) work in a multitude of ways. To evaluate how, we measure ambulatory clinician EHR use in the United States throughout the COVID-19 pandemic.

      Materials and Methods: We use EHR... View Details
      Keywords: Health Care; Electronic Health Records; Productivity; COVID-19 Pandemic; Health Care and Treatment; Health Pandemics; Information Technology; Performance Productivity; United States
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      Holmgren, A Jay, Lance Downing, Mitchell Tang, Christopher Sharp, Christopher Longhurst, and Robert S. Huckman. "Assessing the Impact of the COVID-19 Pandemic on Clinician Ambulatory Electronic Health Record Use." Journal of the American Medical Informatics Association 29, no. 3 (March 2022): 453–460.
      • March 2022 (Revised July 2022)
      • Case

      Nexleaf Analytics: Saving the World Using the Internet of Things

      By: Frank Nagle
      In 2019, a decade after co-founding Nexleaf Analytics, CEO Nithya Ramanathan faced an important decision that would impact the ability of the small, but growing, not-for-profit organization to thrive for another decade. Their sensor technologies and big data analytics... View Details
      Keywords: Corporate Strategy; Collaborative Innovation and Invention; Technological Innovation; Nonprofit Organizations; Competitive Strategy; Patents; Expansion; Information Technology; Health Industry; Health Industry; Health Industry; Health Industry
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      Nagle, Frank. "Nexleaf Analytics: Saving the World Using the Internet of Things." Harvard Business School Case 722-414, March 2022. (Revised July 2022.)
      • Article

      Policies to Influence Perceptions about COVID-19 Risk: The Case of Maps

      By: Claudia Engel, Jonathan Rodden and Marco Tabellini
      Choropleth disease maps have become an important tool for informing the public about the risks posed by COVID-19. In a survey conducted in the U.S. state of Georgia in June 2020, we randomly assigned respondents to view either of two maps. The first one reported... View Details
      Keywords: Disease Surveillance; Health Pandemics; Risk and Uncertainty; Perception; Policy
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      Engel, Claudia, Jonathan Rodden, and Marco Tabellini. "Policies to Influence Perceptions about COVID-19 Risk: The Case of Maps." Science Advances 8, no. 11 (March 18, 2022).
      • March 2022
      • Article

      Where to Locate COVID-19 Mass Vaccination Facilities?

      By: Dimitris Bertsimas, Vassilis Digalakis Jr, Alexander Jacquillat, Michael Lingzhi Li and Alessandro Previero
      The outbreak of COVID-19 led to a record-breaking race to develop a vaccine. However, the limited vaccine capacity creates another massive challenge: how to distribute vaccines to mitigate the near-end impact of the pandemic? In the United States in particular, the new... View Details
      Keywords: Vaccines; COVID-19; Health Care and Treatment; Health Pandemics; Performance Effectiveness; Analytics and Data Science; Mathematical Methods
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      Bertsimas, Dimitris, Vassilis Digalakis Jr, Alexander Jacquillat, Michael Lingzhi Li, and Alessandro Previero. "Where to Locate COVID-19 Mass Vaccination Facilities?" Naval Research Logistics Quarterly 69, no. 2 (March 2022): 179–200.
      • February 2022 (Revised February 2024)
      • Case

      Sekisui House and the In-Home Early Detection Platform

      By: John D. Macomber and Akiko Kanno
      To address an aging population and sales declines, a major Japanese homebuilder considers pivoting to provide and support an in-home health detection platform, in competition with tech companies. This case considers the point of view of major builders regarding how... View Details
      Keywords: Voice Assistants; Architecture; Smart Home; Aging Society; Digitalization; Real Estate; Home Automation; Sensors; Strategy; Digital Platforms; Health Care and Treatment; Housing; Age; Health Industry; Health Industry; Health Industry; Japan
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      Macomber, John D., and Akiko Kanno. "Sekisui House and the In-Home Early Detection Platform." Harvard Business School Case 222-070, February 2022. (Revised February 2024.)
      • February 2022
      • Case

      Cleveland Clinic Abu Dhabi

      By: Linda A. Hill and Emily Tedards
      In 2006, the Cleveland Clinic and Mubadala Investment Company partnered with a bold ambition to deliver world class healthcare in the United Arab Emirates. In 2015, after nearly a decade of planning and construction, Cleveland Clinic Abu Dhabi opened its doors. By... View Details
      Keywords: Organizational Behavior; Culture; Alignment; Organizational Effectiveness; Purpose; Impact; Leadership Development; Diversity; Collaboration; Co-creation; Learning Organizations; Empowerment; Teams; Team Dynamics; Teamwork; Team Effectiveness; Trust; Talent; Talent Development And Retention; Psychological Safety; Organizational Evolution; Coaching; Board; Analytics; Innovation; Data; Data Visualization; Digital Technology; Digital; Customer Experience; Experimentation; Change Management; Data-driven Decision-making; Debates; Ecosystem; Partnership; Telemedicine; Sustainability; Global Organizations; Local; Hospital; Healthcare; United Arab Emirates; Health Care and Treatment; Partners and Partnerships; Globalization; Quality; Organizational Culture; Mission and Purpose; Innovation and Management; Information Technology; Joint Ventures; Leadership; Performance Effectiveness; Abu Dhabi; United Arab Emirates
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      Hill, Linda A., and Emily Tedards. "Cleveland Clinic Abu Dhabi." Harvard Business School Case 422-058, February 2022.
      • February 2022
      • Case

      Cleveland Clinic Abu Dhabi (Abridged)

      By: Linda A. Hill and Emily Tedards
      In 2006, the Cleveland Clinic and Mubadala Investment Company partnered with a bold ambition to deliver world class healthcare in the United Arab Emirates. In 2015, after nearly a decade of planning and construction, Cleveland Clinic Abu Dhabi opened its doors. By... View Details
      Keywords: Organization Behavior; Culture; Alignment; Organizational Effectiveness; Purpose; Impact; Leadership Development; Diversity; Collaboration; Co-creation; Learning Organizations; Empowerment; Teams; Team Dynamics; Teamwork; Team Effectiveness; Trust; Talent; Talent Development And Retention; Psychological Safety; Organizational Evolution; Coaching; Board; Analytics; Innovation; Data; Data Visualization; Digital Technology; Digital; Customer Experience; Experimentation; Change Management; Data-driven Decision-making; Debates; Ecosystem; Partnership; Telemedicine; Sustainability; Global Organizations; Local; Hospital; Healthcare; United Arab Emirates; Health Care and Treatment; Partners and Partnerships; Globalization; Quality; Organizational Culture; Mission and Purpose; Innovation and Management; Information Technology; Joint Ventures; Leadership; Performance Effectiveness; Abu Dhabi; United Arab Emirates
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      Hill, Linda A., and Emily Tedards. "Cleveland Clinic Abu Dhabi (Abridged)." Harvard Business School Case 422-056, February 2022.
      • 2022
      • Working Paper

      Addressing Vaccine Hesitancy: Experimental Evidence from Nine Countries during the COVID-19 Pandemic

      By: Vincenzo Galasso, Vincent Pons, Paola Profeta, Michael Becher, Sylvain Brouard and Martial Foucault
      Millions of people refuse COVID-19 vaccination. Using original data from two surveys in nine OECD countries, we analyze the determinants of anti-vax intentions in December 2020 and show that half of the anti-vax individuals were vaccinated by summer 2021. Vaccinations... View Details
      Keywords: COVID-19; Vaccination; Vaccine Hesitancy; Information Campaigns; Health Pandemics; Behavior; Information
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      Galasso, Vincenzo, Vincent Pons, Paola Profeta, Michael Becher, Sylvain Brouard, and Martial Foucault. "Addressing Vaccine Hesitancy: Experimental Evidence from Nine Countries during the COVID-19 Pandemic." NBER Working Paper Series, No. 29741, February 2022.
      • 2022
      • Working Paper

      E-commerce During COVID: Stylized Facts from 47 Economies

      By: Joel Alcedo, Alberto Cavallo, Bricklin Dwyer, Prachi Mishra and Antonio Spilimbergo
      We study e-commerce across 47 economies and 26 industries during the COVID-19 pandemic using aggregated and anonymized transaction-level data from Mastercard, scaled to represent total consumer spending. The share of online transactions in total consumption increased... View Details
      Keywords: COVID-19 Pandemic; Health Pandemics; Spending; Internet and the Web; Global Range; Analysis; E-commerce
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      Alcedo, Joel, Alberto Cavallo, Bricklin Dwyer, Prachi Mishra, and Antonio Spilimbergo. "E-commerce During COVID: Stylized Facts from 47 Economies." NBER Working Paper Series, No. 29729, February 2022.
      • February 2022 (Revised November 2022)
      • Case

      Nuritas

      By: Mitchell Weiss, Satish Tadikonda, Vincent Dessain and Emer Moloney
      Nora Khaldi had built a technology “to unlock the power of nature” in the service of extending human lifespan and improving health, and now in April 2020 was debating telling her Board of Directors she wanted to put on ice some of her discoveries. Nuritas, the company... View Details
      Keywords: Cash Burn; Cash Flow Analysis; Pharmaceutical Companies; Founder; Artificial Intelligence; AI; Entrepreneurship; Health Testing and Trials; Health Care and Treatment; Decision Making; Market Entry and Exit; AI and Machine Learning; Pharmaceutical Industry
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      Weiss, Mitchell, Satish Tadikonda, Vincent Dessain, and Emer Moloney. "Nuritas." Harvard Business School Case 822-080, February 2022. (Revised November 2022.)
      • January 17, 2022
      • Article

      Reducing Racial Disparities in Cancer Outcomes

      By: Kathy Giusti and Richard G. Hamermesh
      A disproportionate number of Black patients die from cancer in the United States. A key to addressing this problem is enrolling more Black patients in clinical trials. A strategy consisting of these three parts can help accomplish this goal: 1) centralize information... View Details
      Keywords: Cancer Trials; Racial Disparity; Health Testing and Trials; Race; Strategy
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      Giusti, Kathy, and Richard G. Hamermesh. "Reducing Racial Disparities in Cancer Outcomes." Harvard Business Review (website) (January 17, 2022).
      • Article

      Applying Human-Centered Design Principles to Digital Syndromic Surveillance at a Mass Gathering in India: Viewpoint

      By: Ahmed Shaikh, Abhishek Bhatia, Ghanshyam Yadav, Shashwat Hora, Chung Won, Mark Shankar, Aaron Heerboth, Prakash Vemulapalli, Paresh Navalkar, Kunal Oswal, Clay Heaton, Sujata Saunik, Tarun Khanna and Satchit Balsari
      In the wake of the COVID-19 pandemic, digital health tools have been deployed by governments around the world to advance clinical and population health objectives. Few interventions have been successful or have achieved sustainability or scale. In India, government... View Details
      Keywords: Digital Health Tools; Human-centered Design; Health Care and Treatment; Mobile and Wireless Technology; Design; Technology Adoption
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      Shaikh, Ahmed, Abhishek Bhatia, Ghanshyam Yadav, Shashwat Hora, Chung Won, Mark Shankar, Aaron Heerboth, Prakash Vemulapalli, Paresh Navalkar, Kunal Oswal, Clay Heaton, Sujata Saunik, Tarun Khanna, and Satchit Balsari. "Applying Human-Centered Design Principles to Digital Syndromic Surveillance at a Mass Gathering in India: Viewpoint." Journal of Medical Internet Research 24, no. 1 (January 2022).
      • January 2022
      • Article

      Global Behaviors, Perceptions, and the Emergence of Social Norms at the Onset of the COVID-19 Pandemic

      By: Lukas Hensel, Marc Witte, Stefano Caria, Thiemo Fetzer, Stefano Fiorin, Friedrich M. Goetz, Margarita Gomez, Johannes Haushofer, Andriy Ivchenko, Gordon T. Kraft-Todd, Elena Reutskaja, Christopher Roth, Erez Yoeli and Jon M. Jachimowicz
      We conducted a large-scale survey covering 58 countries and over 100,000 respondents between late March and early April 2020 to study beliefs and attitudes towards citizens' and governments' responses at the onset of the COVID-19 pandemic. Most respondents reported... View Details
      Keywords: COVID-19; Government Regulation; Social Norms; Health Pandemics; Governing Rules, Regulations, and Reforms; Behavior; Perception; Global Range; Surveys
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      Hensel, Lukas, Marc Witte, Stefano Caria, Thiemo Fetzer, Stefano Fiorin, Friedrich M. Goetz, Margarita Gomez, Johannes Haushofer, Andriy Ivchenko, Gordon T. Kraft-Todd, Elena Reutskaja, Christopher Roth, Erez Yoeli, and Jon M. Jachimowicz. "Global Behaviors, Perceptions, and the Emergence of Social Norms at the Onset of the COVID-19 Pandemic." Journal of Economic Behavior & Organization 193 (January 2022): 473–496.
      • January 2022
      • Article

      Rational Habit Formation: Experimental Evidence from Handwashing in India

      By: Reshmaan Hussam, Atonu Rabbani, Giovanni Reggiani and Natalia Rigol
      We test the predictions of the rational addiction model, reconceptualized as rational habit formation, in the context of handwashing in rural India. To track handwashing, we design soap dispensers with timed sensors. We test for rational habit formation by informing... View Details
      Keywords: Handwashing; Habit; Monitoring; Behavior; Health; Motivation and Incentives
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      Hussam, Reshmaan, Atonu Rabbani, Giovanni Reggiani, and Natalia Rigol. "Rational Habit Formation: Experimental Evidence from Handwashing in India." American Economic Journal: Applied Economics 14, no. 1 (January 2022): 1–41. (Lead Article.)
      • Article

      Social Technology: An Interdisciplinary Approach to Improving Care for Older Adults

      By: Arthur Kleinman, Hongtu Chen, Sue E. Levkoff, Ann Forsyth, David E. Bloom, Winnie Yip, Tarun Khanna, Conor J. Walsh, David Perry, Ellen W. Seely, Anne S. Kleinman, Yan Zhang, Yuan Wang, Jun Jing, Tianshu Pan, Ning An, Zhenggang Bai, Jiexiu Wang, Qing Liu and Fawwaz Habbal
      Population aging is a defining demographic reality of our era. It is associated with an increase in the societal burden of delivering care to older adults with chronic conditions or frailty. How to integrate global population aging and technology development to help... View Details
      Keywords: Health Care and Treatment; Age; Service Delivery; Information Technology; Collaborative Innovation and Invention
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      Kleinman, Arthur, Hongtu Chen, Sue E. Levkoff, Ann Forsyth, David E. Bloom, Winnie Yip, Tarun Khanna, Conor J. Walsh, David Perry, Ellen W. Seely, Anne S. Kleinman, Yan Zhang, Yuan Wang, Jun Jing, Tianshu Pan, Ning An, Zhenggang Bai, Jiexiu Wang, Qing Liu, and Fawwaz Habbal. "Social Technology: An Interdisciplinary Approach to Improving Care for Older Adults." Art. 729149. Frontiers in Public Health 9 (2021).
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