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      • Faculty Publications  (237)

      Biotechnology IndustryRemove Biotechnology Industry →

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      • February 2012
      • Article

      A 'Core Periphery' Framework to Navigate Emerging Market Governments—Qualitative Evidence from a Biotechnology Multinational

      By: Prithwiraj Choudhury, James Geraghty and Tarun Khanna
      We build on the emerging literature of influence-based models to study how multinational firms can navigate host governments. Our "core-periphery" framework posits that the actions that an MNC takes with actors in what we call the "periphery"—comprised of state,... View Details
      Keywords: Emerging Markets; Multinational Firms and Management; Business and Government Relations; Power and Influence; Framework; Biotechnology Industry; Massachusetts; Brazil; China; Costa Rica; France; India
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      Choudhury, Prithwiraj, James Geraghty, and Tarun Khanna. "A 'Core Periphery' Framework to Navigate Emerging Market Governments—Qualitative Evidence from a Biotechnology Multinational." Global Strategy Journal 2, no. 1 (February 2012): 71–87.
      • October 2011
      • Case

      Gene Sequencing: Staking a Position in an Expanding Industry

      By: Richard G. Hamermesh, Mara Aspinall and Phillip Andrews
      Towards the end of 2010, companies in the gene sequencing industry were pushing aggressive R&D programs to develop technologies and products in the race to sequence the entire human genome at a cost of $1,000. It remained to be seen when the "$1,000 genome" would... View Details
      Keywords: Genetics; Business Growth and Maturation; Business Plan; Competition; Venture Capital; Biotechnology Industry
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      Hamermesh, Richard G., Mara Aspinall, and Phillip Andrews. "Gene Sequencing: Staking a Position in an Expanding Industry." Harvard Business School Case 812-004, October 2011.
      • September 2011
      • Teaching Note

      Tengion: Bringing Regenerative Medicine to Life (TN)

      By: Elie Ofek and Natalie Kindred
      Teaching Note for 510031. View Details
      Keywords: Partners and Partnerships; Production; Marketing; Cash; Health Care and Treatment; Medical Specialties; Research and Development; Biotechnology Industry
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      Ofek, Elie, and Natalie Kindred. "Tengion: Bringing Regenerative Medicine to Life (TN)." Harvard Business School Teaching Note 512-023, September 2011.
      • June 2011 (Revised October 2013)
      • Case

      Gene Patents (A)

      By: Richard Hamermesh, David Kiron and Phillip Andrews
      In March 2010, U.S. District Court Judge Robert Sweet overturned 30 years of legal precedent and ruled that unaltered human genes could not be patented. This case reviews patent law and how it relates to our increasing knowledge of the Human Genome. The case issues... View Details
      Keywords: Courts and Trials; Patents; Genetics; Judgments; Science-Based Business; Biotechnology Industry; United States
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      Hamermesh, Richard, David Kiron, and Phillip Andrews. "Gene Patents (A)." Harvard Business School Case 811-089, June 2011. (Revised October 2013.)
      • April 2011
      • Teaching Note

      Office of Technology Transfer - Shanghai Institutes for Biological Sciences (TN)

      By: Willy Shih and Sen Chai
      Teaching Note for 611057. View Details
      Keywords: Patents; Rights; Infrastructure; Multinational Firms and Management; Research and Development; Complexity; Commercialization; Technology Adoption; Motivation and Incentives; Biotechnology Industry; Biotechnology Industry; Shanghai
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      Shih, Willy, and Sen Chai. "Office of Technology Transfer - Shanghai Institutes for Biological Sciences (TN)." Harvard Business School Teaching Note 611-058, April 2011.
      • March 2011 (Revised June 2012)
      • Case

      Office of Technology Transfer - Shanghai Institutes for Biological Sciences

      By: Willy Shih, Sen Chai, Kamen Bliznashki and Courtney Hyland
      Gordon Zong is trying to teach Chinese universities and research institutes how to do effective technology transfer and IP licensing, but he is trying to do it in an environment with weak property rights and an underdeveloped support infrastructure. As the managing... View Details
      Keywords: Multinational Firms and Management; Patents; Knowledge Management; Law Enforcement; Business and Government Relations; Research and Development; Biotechnology Industry; Biotechnology Industry; China
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      Shih, Willy, Sen Chai, Kamen Bliznashki, and Courtney Hyland. "Office of Technology Transfer - Shanghai Institutes for Biological Sciences." Harvard Business School Case 611-057, March 2011. (Revised June 2012.)
      • March 2011 (Revised February 2012)
      • Case

      Innovation and Growth at Actelion Ltd.

      By: Gary P. Pisano, Daniela Beyersdorfer and Ruth Dittrich
      In late 2010, Jean-Paul Clozel, CEO of the Swiss biotech pharmaceuticals firm Actelion, looks back on a successful decade. The small venture that he had started with a few of his scientist colleagues in the late 1990s to discover novel medicine in a research-driven... View Details
      Keywords: Business Model; Talent and Talent Management; Innovation and Management; Leadership; Growth and Development Strategy; Product Development; Organizational Culture; Research and Development; Biotechnology Industry; Biotechnology Industry; Switzerland
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      Pisano, Gary P., Daniela Beyersdorfer, and Ruth Dittrich. "Innovation and Growth at Actelion Ltd." Harvard Business School Case 611-065, March 2011. (Revised February 2012.)
      • March 2011
      • Case

      MorphoSys AG: The Evolution of a Biotechnology Business Model

      By: Gary P. Pisano, Ryan Johnson and Carin-Isabel Knoop
      In the biotech world, the 18-year-old Munich-based company MorphoSys was a rarity: it was profitable. The company achieved this profitability not by developing and selling its own drugs, but by licensing access to its proprietary library of human antibodies. Recently,... View Details
      Keywords: Business Model; Profit; Intellectual Property; Rights; Risk Management; Digital Platforms; Product Development; Business and Shareholder Relations; Vertical Integration; Biotechnology Industry; Munich
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      Pisano, Gary P., Ryan Johnson, and Carin-Isabel Knoop. "MorphoSys AG: The Evolution of a Biotechnology Business Model." Harvard Business School Case 611-046, March 2011.
      • January 2011 (Revised March 2011)
      • Case

      Predictive Biosciences

      By: Thomas R. Eisenmann, Jeffrey J. Bussgang and David Kiron
      A small cancer diagnostics start-up is deciding whether to acquire a laboratory to make and sell its bladder cancer test or build its own manufacturing and sales team. View Details
      Keywords: Mergers and Acquisitions; Factories, Labs, and Plants; Business Startups; Entrepreneurship; Health Testing and Trials; Growth and Development Strategy; Product Development; Biotechnology Industry
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      Eisenmann, Thomas R., Jeffrey J. Bussgang, and David Kiron. "Predictive Biosciences." Harvard Business School Case 811-015, January 2011. (Revised March 2011.)
      • January 2011 (Revised January 2012)
      • Supplement

      The Case of the Unidentified Healthcare Companies2010 (CW)

      By: Richard M.J. Bohmer, Ethan S Bernstein, Margarita Krivitski and Srinidhi Reddy
      This case presents financial statements and selected rations for 14 unidentified healthcare organizations and asks that each set of financial information be matched with one of the following healthcare companies: a biotechnology firm, a community nursing company, a... View Details
      Keywords: Financial Statements; Financial Management; Health Care and Treatment; Biotechnology Industry; Biotechnology Industry
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      Bohmer, Richard M.J., Ethan S. Bernstein, Margarita Krivitski, and Srinidhi Reddy. "The Case of the Unidentified Healthcare Companies2010 (CW)." Harvard Business School Spreadsheet Supplement 611-701, January 2011. (Revised January 2012.)
      • January 2011 (Revised January 2012)
      • Case

      The Case of the Unidentified Healthcare Companies2010

      By: Richard Bohmer, Ethan Bernstein, Margarita Krivitski and Srinidhi Reddy
      This case presents financial statements and selected ratios for 14 unidentified healthcare organizations and asks that each set of financial information be matched with one of the following healthcare companies: a biotechnology firm, a community nursing company, a... View Details
      Keywords: Financial Reporting; Financial Statements; Health Care and Treatment; Health Industry
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      Bohmer, Richard, Ethan Bernstein, Margarita Krivitski, and Srinidhi Reddy. "The Case of the Unidentified Healthcare Companies2010." Harvard Business School Case 611-043, January 2011. (Revised January 2012.)
      • December 2010
      • Teaching Note

      Roche's Acquisition of Genentech (TN)

      By: Bo Becker and Carliss Y. Baldwin
      Teaching Note for 210-040. View Details
      Keywords: Mergers and Acquisitions; Stock Shares; Opportunities; Strategy; Organizational Culture; Value; Negotiation Tactics; Biotechnology Industry; Biotechnology Industry
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      Becker, Bo, and Carliss Y. Baldwin. "Roche's Acquisition of Genentech (TN)." Harvard Business School Teaching Note 211-039, December 2010.
      • November 2010 (Revised July 2012)
      • Teaching Note

      Arcadia Biosciences: Seeds of Change (TN)

      By: Arthur A. Daemmrich and Forest L. Reinhardt
      Teaching Note for 709019. View Details
      Keywords: Biotechnology Industry
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      Daemmrich, Arthur A., and Forest L. Reinhardt. "Arcadia Biosciences: Seeds of Change (TN)." Harvard Business School Teaching Note 711-042, November 2010. (Revised July 2012.)
      • September 2010 (Revised July 2013)
      • Case

      Alnylam Pharmaceuticals: Building Value from the IP Estate

      By: Willy C. Shih and Sen Chai
      The learning objective of this case is to help students recognize the interplay between intellectual property (IP) rights and corporate strategy. We do this by examining what is a fairly atypical circumstance today in which a single firm is able to secure what it... View Details
      Keywords: Patents; Lawsuits and Litigation; Rights; Competitive Strategy; Corporate Strategy; Biotechnology Industry; Biotechnology Industry; United States
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      Shih, Willy C., and Sen Chai. "Alnylam Pharmaceuticals: Building Value from the IP Estate." Harvard Business School Case 611-009, September 2010. (Revised July 2013.)
      • 2010
      • Working Paper

      Venture Capital Investment in the Clean Energy Sector

      By: Shikhar Ghosh and Ramana Nanda
      We examine the extent to which venture capital is adequately positioned for the rapid commercialization of clean energy technologies in the United States. While there are several startups in clean energy that are well-suited to the traditional venture capital... View Details
      Keywords: Business Startups; Energy Generation; Venture Capital; Investment; Governing Rules, Regulations, and Reforms; Technological Innovation; Competition; Energy Industry; Energy Industry; United States
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      Ghosh, Shikhar, and Ramana Nanda. "Venture Capital Investment in the Clean Energy Sector." Harvard Business School Working Paper, No. 11-020, August 2010.
      • June 2010 (Revised May 2017)
      • Teaching Note

      Sydney IVF: Stem Cell Research

      By: Robert Simons and Kathryn Rosenberg
      Teaching Note for 109017. View Details
      Keywords: Strategy And Execution; Management Control Systems; Levers Of Control; Strategy; Risk Management; Decisions; Cooperative Ownership; Product Development; Moral Sensibility; Governing Rules, Regulations, and Reforms; Expansion; Science-Based Business; Research; Management Practices and Processes; Business Subsidiaries; Biotechnology Industry; Sydney
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      Simons, Robert, and Kathryn Rosenberg. "Sydney IVF: Stem Cell Research." Harvard Business School Teaching Note 110-092, June 2010. (Revised May 2017.)
      • June 2010
      • Teaching Note

      Monsanto: Helping Farmers Feed the World (TN)

      By: David E. Bell and Mary Louise Shelman
      Teaching Note for [510025]. View Details
      Keywords: Food; Production; Adoption; Leadership Style; Globalized Markets and Industries; Performance Productivity; Agriculture and Agribusiness Industry; Agriculture and Agribusiness Industry
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      Bell, David E., and Mary Louise Shelman. "Monsanto: Helping Farmers Feed the World (TN)." Harvard Business School Teaching Note 510-101, June 2010.
      • March 2010 (Revised May 2012)
      • Case

      Myelin Repair Foundation: Accelerating Drug Discovery Through Collaboration

      By: Karim R. Lakhani and Paul R. Carlile
      This case presents the Myelin Repair Foundation's accelerated research collaboration model for drug discovery. It highlights the challenges of building a multi-disciplinary and multi-institutional research collaboration that is attempting to create a treatment for... View Details
      Keywords: Research and Development; Intellectual Property; Risk and Uncertainty; Strategic Planning; Collaborative Innovation and Invention; Health Disorders; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry
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      Lakhani, Karim R., and Paul R. Carlile. "Myelin Repair Foundation: Accelerating Drug Discovery Through Collaboration." Harvard Business School Case 610-074, March 2010. (Revised May 2012.)
      • February 2010 (Revised September 2011)
      • Case

      Roche's Acquisition of Genentech

      By: Carliss Y. Baldwin, Bo Becker and Vincent Marie Dessain
      Franz Humer, CEO of the Roche Group, must decide whether to mount a hostile tender offer for the publicly-owned shares of Roche's biotechnology subsidiary, Genentech. The case provides opportunities to analyze Roche's strategy with respect to Genentech, the pros and... View Details
      Keywords: Mergers and Acquisitions; Business Subsidiaries; Negotiation Offer; Organizational Culture; Corporate Strategy; Biotechnology Industry; Biotechnology Industry; Switzerland
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      Baldwin, Carliss Y., Bo Becker, and Vincent Marie Dessain. "Roche's Acquisition of Genentech." Harvard Business School Case 210-040, February 2010. (Revised September 2011.)
      • February 2010
      • Case

      Amyris Biotechnologies: Commercializing Biofuel

      By: Gary P. Pisano and Alison Berkley Wagonfeld
      In 2009, Amyris Biotechnologies was building a plant in Brazil that used synthetic biology to convert sugarcane into both renewable fuels and renewable chemicals. The Amyris' marketing team was investigating the commercial interest for both types of products, while the... View Details
      Keywords: Renewable Energy; Chemicals; Risk Management; Product Marketing; Product Development; Production; Environmental Sustainability; Commercialization; Biotechnology Industry; Brazil
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      Pisano, Gary P., and Alison Berkley Wagonfeld. "Amyris Biotechnologies: Commercializing Biofuel." Harvard Business School Case 610-031, February 2010.
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