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  • June 2003 (Revised March 2008)
  • Case

Schering-Plough and Genome Therapeutics: Discovering an Asthma Gene

By: Regina E. Herzlinger and Marc Aquino
Personalized medicine requires the identification of mutated genes. Schering-Plough's search for the one related to asthma requires finding families with the disease. Examines the industry that helps conduct such research, including contract research organizations. View Details
Keywords: Health Disorders; Research and Development; Genetics; Pharmaceutical Industry; Pharmaceutical Industry
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Herzlinger, Regina E., and Marc Aquino. "Schering-Plough and Genome Therapeutics: Discovering an Asthma Gene." Harvard Business School Case 303-044, June 2003. (Revised March 2008.)
  • February 1997 (Revised June 1999)
  • Teaching Note

Massachusetts General Hospital: CABG Surgery (A) TN

By: Steven C. Wheelwright
Teaching Note for (9-696-015). View Details
Keywords: Pharmaceutical Industry; Pharmaceutical Industry; Massachusetts
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Wheelwright, Steven C. "Massachusetts General Hospital: CABG Surgery (A) TN." Harvard Business School Teaching Note 697-074, February 1997. (Revised June 1999.)
  • November 1995 (Revised March 2004)
  • Case

Massachusetts General Hospital: CABG Surgery (A)

By: Steven C. Wheelwright and James Weber
A cross-functional team at Massachusetts General Hospital tries to reengineer the service delivery process (the "care path") for heart bypass surgery (CABG) in order to shorten hospital stays (and lower costs) while maintaining/enhancing the quality of care provided. View Details
Keywords: Health Care and Treatment; Medical Specialties; Business Processes; Mission and Purpose; Product Positioning; Product Marketing; Management Practices and Processes; Customer Satisfaction; Service Delivery; Service Operations; Fair Value Accounting; Ethics; Pharmaceutical Industry; Pharmaceutical Industry; Massachusetts
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Wheelwright, Steven C., and James Weber. "Massachusetts General Hospital: CABG Surgery (A)." Harvard Business School Case 696-015, November 1995. (Revised March 2004.)
  • September 1997 (Revised October 1997)
  • Case

Bayer AG (A)

By: John A. Quelch
Bayer's senior executives convene in Germany to consider submitting a $1 billion bid that would recover the Bayer brand name and trademark cross in North America, both of which were confiscated by the U.S. government after World War I. The group also sets out to assess... View Details
Keywords: Management Teams; Brands and Branding; War; Communication; Trademarks; Acquisition; Government and Politics; Pharmaceutical Industry; Pharmaceutical Industry; Germany; North America; United States
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Quelch, John A., and Robin Root. "Bayer AG (A)." Harvard Business School Case 598-031, September 1997. (Revised October 1997.)
  • November 1991 (Revised December 1991)
  • Case

SmithKline Beecham Animal Health

By: Ray A. Goldberg
Keywords: Pharmaceutical Industry; Pharmaceutical Industry
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Goldberg, Ray A. "SmithKline Beecham Animal Health." Harvard Business School Case 592-053, November 1991. (Revised December 1991.)
  • 18 Nov 2014
  • First Look

First Look: November 18

were the strengths and challenges facing this model? How would the model evolve in the future? And how would new, similar collaboration models surfacing at other major pharmaceutical companies pose a threat to the Pfizer model? Purchase... View Details
Keywords: Sean Silverthorne
  • 21 Nov 2006
  • First Look

First Look: November 21, 2006

cost to identify and investigate. The Effect of File Sharing on Record Sales: An Empirical Analysis Authors:Felix Oberholzer-Gee and Koleman Strumpf Periodical:Journal of Political Economy (forthcoming) Abstract For industries ranging from software to View Details
Keywords: Sean Silverthorne
  • 12 Oct 2006
  • First Look

First Look: October 12, 2006

pharmaceutical companies, government regulators—can play a role in righting the industry. The payoff? Valuable improvements in health care and a shinier future for human well-being. Pre-order this book:... View Details
Keywords: Sean Silverthorne
  • 28 Aug 2017
  • Research & Ideas

Should Industry Competitors Cooperate More to Solve World Problems?

to be innovative, really providing service to customers and attracting top talent. They are now becoming utilities, facing an incredible amount of regulation largely because of their own conduct failures. Third, they could reduce risk from exposure to major scandals.... View Details
Keywords: by Sean Silverthorne; Financial Services; Manufacturing; Agriculture & Agribusiness; Mining
  • April 2024 (Revised November 2024)
  • Case

Moderna: Pioneering a People Platform to Accelerate Science Innovation

By: Tatiana Sandino, Emil Dy and Samuel Grad
Moderna was founded in 2010 to explore how messenger ribonucleic acid (mRNA) could be used to create breakthrough medicines by encoding instructions for the body to create antibodies. When Stéphane Bancel (HBS 2000) took over in 2011, he bet on the potential of this... View Details
Keywords: Disruptive Innovation; Talent and Talent Management; Selection and Staffing; AI and Machine Learning; Digital Strategy; Innovation and Management; Leadership Development; Management Practices and Processes; Management Systems; Organizational Culture; Performance Evaluation; Alignment; Employee Relationship Management; Science-Based Business; Expansion; Pharmaceutical Industry; Pharmaceutical Industry; United States
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Sandino, Tatiana, Emil Dy, and Samuel Grad. "Moderna: Pioneering a People Platform to Accelerate Science Innovation." Harvard Business School Case 124-091, April 2024. (Revised November 2024.)
  • November 2020
  • Teaching Note

Valuing Celgene's CVR

By: Benjamin C. Esty and Daniel Fisher
Teaching Note for HBS Case No. 221-031. When Bristol-Myers Squibb (BMS) acquired Celgene Corporation in November 2019, Celgene shareholders received cash, BMS stock, and a contingent value right (CVRs) that would pay $9 if the U.S. Food and Drug Administration (FDA)... View Details
Keywords: Mergers and Acquisitions; Valuation; Value; Judgments; Decision Making; Cash Flow; Financial Instruments; Cognition and Thinking; Pharmaceutical Industry; Pharmaceutical Industry; United States
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Esty, Benjamin C., and Daniel Fisher. "Valuing Celgene's CVR." Harvard Business School Teaching Note 221-036, November 2020.
  • Article

Trends and Predictors of Biomedical Research Quality, 1990–2015: A Meta-Research Study

By: Maryaline Catillon
Keywords: Biomedical Research; R&D; Innovation; Technology; Drug Trials; RCT; Health; Healthcare; Health Care And Treatment; Health Care Policy; Innovation and Invention; Innovation Strategy; Research and Development; Technological Innovation; Pharmaceutical Industry; Pharmaceutical Industry
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Catillon, Maryaline. "Trends and Predictors of Biomedical Research Quality, 1990–2015: A Meta-Research Study." BMJ Open 9, no. 9 (September 2019).
  • September 2012
  • Case

SCMS: Battling HIV/AIDS in Africa

By: Ananth Raman, Noel Watson, Santiago Kraiselburd and Emmanuel Akili
In 2005, USAID and the U.S. President's Emergency Plan for AIDS Relief (PEPFAR), created the Supply Chain Management System (SCMS) to procure and distribute essential medicines and supplies; provide technical assistance to transform existing supply chains; and... View Details
Keywords: HIV; AIDS; Procurement Coordination; Developing Countries; Healthcare; Public Health; Ethiopia; Supply Systems For Healthcare Delivery In Developing Countries; Healthcare Logistics Industry; Health Disorders; Health Care and Treatment; Service Delivery; Supply Chain Management; Logistics; Developing Countries and Economies; Programs; Transition; Strategy; Pharmaceutical Industry; Pharmaceutical Industry; Ethiopia; Africa
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Raman, Ananth, Noel Watson, Santiago Kraiselburd, and Emmanuel Akili. "SCMS: Battling HIV/AIDS in Africa." Harvard Business School Case 613-023, September 2012.
  • February 2010
  • Background Note

Millipore Background Note

By: Elie Ofek and Natalie Kindred
This note provides background on Millipore Corporation, a global provider of products and services used primarily in the discovery, development and production of therapeutic drugs. With a track record of quickly adapting to the evolving needs of its customers,... View Details
Keywords: Organizational Change and Adaptation; Customer Focus and Relationships; Pharmaceutical Industry; Pharmaceutical Industry
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Ofek, Elie, and Natalie Kindred. "Millipore Background Note." Harvard Business School Background Note 510-059, February 2010.
  • March 2009
  • Teaching Note

Antegren: A Beacon of Hope (TN)

By: Joshua D. Margolis
Teaching Note for [408025], [408026], [408027], and [408028]. View Details
Keywords: Ethics; Corporate Social Responsibility and Impact; Decision Choices and Conditions; Crisis Management; Pharmaceutical Industry; Pharmaceutical Industry
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Margolis, Joshua D. "Antegren: A Beacon of Hope (TN)." Harvard Business School Teaching Note 409-096, March 2009.
  • Article

A Blueprint for Pharmacy Benefits Managers to Increase Value

By: William Shrank, Michael E. Porter, Sachin H. Jain and Niteesh K. Choudhary
Pharmacy benefits managers (PBMs) have a unique opportunity to promote public health and generate value in the healthcare system. However, PBMs are largely evaluated on their ability to control costs rather than improve health. PBMs should be evaluated along three... View Details
Keywords: Opportunities; Health; System; Cost Management; Partners and Partnerships; Motivation and Incentives; Value; Innovation and Invention; Performance Effectiveness; Pharmaceutical Industry; Pharmaceutical Industry
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Shrank, William, Michael E. Porter, Sachin H. Jain, and Niteesh K. Choudhary. "A Blueprint for Pharmacy Benefits Managers to Increase Value." American Journal of Managed Care 15, no. 2 (February 2009).
  • April 1989
  • Supplement

Novel Combination of Two Drugs (C)

By: Regina E. Herzlinger
Keywords: Health; Health Care and Treatment; Pharmaceutical Industry; Pharmaceutical Industry
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Herzlinger, Regina E. "Novel Combination of Two Drugs (C)." Harvard Business School Supplement 189-170, April 1989.
  • April 1989
  • Supplement

Novel Combination of Two Drugs (B)

By: Regina E. Herzlinger
Keywords: Health; Health Care and Treatment; Pharmaceutical Industry; Pharmaceutical Industry
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Herzlinger, Regina E. "Novel Combination of Two Drugs (B)." Harvard Business School Supplement 189-169, April 1989.
  • 2006
  • Chapter

BioRisk: interleukin-2 from laboratory to market in the United States and Germany

By: Arthur A. Daemmrich
Keywords: Product Development; Risk and Uncertainty; Health Testing and Trials; Pharmaceutical Industry; Pharmaceutical Industry; United States; Germany
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Daemmrich, Arthur A. "BioRisk: interleukin-2 from laboratory to market in the United States and Germany ." In The Risks of Medical Innovation: Risk Perception and Assessment in Historical Context, edited by Thomas Schlich and Ulrich Tröhler, 242–261. Routledge, 2006.
  • June 2003 (Revised October 2004)
  • Case

Novartis: The Challenge of Success (C)

By: Sandra J. Sucher and Stacy McManus
Supplements the (A) and (B) cases. View Details
Keywords: Pharmaceutical Industry; Pharmaceutical Industry
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Sucher, Sandra J., and Stacy McManus. "Novartis: The Challenge of Success (C)." Harvard Business School Case 603-045, June 2003. (Revised October 2004.)
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