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  • 13 Nov 2007
  • Research & Ideas

Six Steps for Reinvigorating America

innovation and the opportunity to participate in the "white coat" economy and life sciences revolution of the 21st century. Writes a new social contract based on real family values, creating fair and flexible workplaces that are... View Details
Keywords: by Sean Silverthorne
  • 05 Jun 2013
  • Op-Ed

Corporate Leaders Need to Step Up on Climate Change

Green initiatives are ubiquitous these days, implemented with zeal at companies like Dupont, IBM, Walmart, and Walt Disney. The programs being rolled out—lighting retrofits, zero-waste factories, and carpool incentives—save money and provide a green glow. Most large... View Details
Keywords: by Michael Toffel & Auden Schendler
  • 2025
  • Working Paper

Magnetic Resonance Imaging—High Quality and Radiation Free: Case Histories of Transformational Advances

By: Srikant M. Datar, Amar Bhidé and Katherine Stebbins
This case history describes how Magnetic Resource Imaging (MRI) came to complement – and partially replace -- computed tomography (CT) imaging of soft tissue. Specifically, we chronicle 1) the development of foundational techniques and prototypes (through the 1970s);... View Details
Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms
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Datar, Srikant M., Amar Bhidé, and Katherine Stebbins. "Magnetic Resonance Imaging—High Quality and Radiation Free: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 20-001, July 2019. (Revised January 2025.)
  • 2025
  • Working Paper

Mammography - Early Detection, Precise Diagnoses: Case Histories of Transformational Advances

By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins
This case history describes how the development of x-ray-based techniques and equipment (“mammography”) led to widespread screening for breast cancer and enabled “minimally invasive” biopsies of breast tumors. Specifically, we chronicle how: 1) new protocols and... View Details
Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms
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Bhidé, Amar, Srikant M. Datar, and Katherine Stebbins. "Mammography - Early Detection, Precise Diagnoses: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 20-002, July 2019. (Revised January 2025.)
  • 2024
  • Working Paper

Antibiotic Treatments for Ulcers--Eradicating H-Pylori Infections: Case Histories of Transformational Advances

By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins
This case history describes how a chance discovery of bacteria that infect stomach linings completely changed how physicians treat ulcers. Specifically, we chronicle how: 1) two Australian physicians brought the bacterial infection to the world’s attention and... View Details
Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms
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Bhidé, Amar, Srikant M. Datar, and Katherine Stebbins. "Antibiotic Treatments for Ulcers--Eradicating H-Pylori Infections: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 20-006, July 2019. (Revised May 2024.)
  • 07 Oct 2015
  • What Do You Think?

What is the Best Immigration Model for the US?

to return to their countries of origin....” Ben commented that “We have a need for skilled and unskilled labor here (in the U.S.) and we value inclusion and integration... (But) I think our government shouldn’t copy any other country’s... View Details
Keywords: by James Heskett
  • 13 Jul 2011
  • Research & Ideas

Experimental Researcher Helps Improve Health Care in Zambia

Sometimes big ideas start with small experiments. That's been the experience of Harvard Business School professor Nava Ashraf, whose experimental approach to research in developing countries has produced insights that have influenced View Details
Keywords: by Roger Thompson; Health
  • 25 May 2016
  • Research & Ideas

How Consumers and Businesses are Reshaping Public Health

be headquartered in England in order to achieve a lower corporate tax rate. The British government favored the merger as it would boost the high-priority life sciences sector, but little attention was paid to whether the integration of... View Details
Keywords: by John A. Quelch; Health
  • 15 Feb 2017
  • Op-Ed

What Africa Can Teach the United States About Funding Infrastructure Projects

investors, and builders can learn from the African experience, where public-private partnerships and deployments of new technologies are illuminating new ways to approach the task of funding infrastructure despite a scarcity of government... View Details
Keywords: by John Macomber; Construction
  • 18 Nov 2010
  • Research & Ideas

GM’s IPO: Back to the Future

Steve Rattner, who chaired the government task force, found the initial assessments of their needs woefully understated and badly documented, reflecting decades of lost market share and destroyed shareholder value. The deal that was... View Details
Keywords: by Staff; Auto
  • 2024
  • Working Paper

Coronary Artery Bypass Grafting—Impossible to Routine: Case Histories of Transformational Advances

By: Amar Bhidé, Srikant M. Datar and Fabio Villa
We describe how Coronary Artery Bypass Grafting (CABG, or more popularly, “bypass”) operations revolutionized the treatment of coronary disease (that can produce fatal heart attacks and debilitating angina). Specifically, we chronicle the: 1) development of the... View Details
Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms
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Bhidé, Amar, Srikant M. Datar, and Fabio Villa. "Coronary Artery Bypass Grafting—Impossible to Routine: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 20-010, July 2019. (Revised May 2024.)
  • 20 Jan 2017
  • Research & Ideas

Here’s How Businessman Trump Is Likely to Approach the Presidency

Administration I study business leaders, government leaders, religious leaders, social activists, and other individuals — past and present — who exercise real, worthy impact. As a historian, I don’t see huge differences among political... View Details
Keywords: by Christina Pazzanese
  • 24 Jan 2005
  • Research & Ideas

Entrepreneurial Hospital Pioneers New Model

never see in any other hospital. As soon as a heart patient arrives at the border, the colleague alerts Shetty, Shetty alerts the Indian government, the Indian government kicks into high gear, the patient is air-lifted to the hospital,... View Details
Keywords: by Martha Lagace; Health
  • 16 Feb 2012
  • Op-Ed

Nitin Nohria: Why US Competitiveness Matters

economic inequality worrisome. They see that US corporations are skittish about making investments in a time of uncertainty about government policy, taxes, and regulations. They hear too many American CEOs talk about choosing to postpone... View Details
Keywords: by Nitin Nohria
  • 26 Oct 2017
  • Research Event

In an Era of 'Fake News,' What is the Future of Advertising and Publishing?

White House popularized the term “fake news,” the influence of social media advertising and online publishing requires serious reexamination. That began to happen October 24 at the The Future of Advertising and Publishing conference held at the Harvard View Details
Keywords: by Jen Deaderick; Media & Broadcasting; Journalism & News
  • 06 Apr 2007
  • What Do You Think?

Will Market Forces Stop Global Warming?

Summing Up Debate on this month's questions occurred on at least three levels. Is global warming occurring? Do humans (primarily through CO2 emissions) have much to do with it? Should we rely on market forces to provide appropriate responses, or will this require... View Details
Keywords: by Jim Heskett; Energy; Utilities
  • 17 Oct 2012
  • Research & Ideas

America Needs a Manufacturing Renaissance

sciences that laid the institutional foundations for innovations in semiconductors, high-speed computers, computer graphics, broadband communications, mobile telephony, the Internet, and modern genomics-based methods of drug discovery.... View Details
Keywords: by Gary P. Pisano & Willy C. Shih; Manufacturing
  • 06 Jun 2005
  • Research & Ideas

Microsoft vs. Open Source: Who Will Win?

for Linux to take over Windows. The questions that we address are: Is Linux's superior demand-side learning sufficient to win out? What is the effect of forced procurement by governments and some large corporations on the long-run... View Details
Keywords: by Sean Silverthorne; Technology
  • 06 Apr 2016
  • Research & Ideas

Should Entrepreneurs Pitch Products or Ideas for Products?

In trying to secure financial backing for a new product, independent innovators generally face the question of how much to invest in development before showing it around. Should they create, say, a working prototype (and maybe even... View Details
Keywords: by Carmen Nobel; Motion Pictures & Video; Entertainment & Recreation; Banking
  • 2024
  • Working Paper

Prozac—Controversial Blockbuster: Case Histories of Transformational Advances

By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins
This case history describes the development of Prozac, a blockbuster drug that transformed the treatment of depression – and became a cultural phenomenon in the United States. Specifically, we chronicle the: 1) prior treatments for depression and the research that... View Details
Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms
Citation
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Bhidé, Amar, Srikant M. Datar, and Katherine Stebbins. "Prozac—Controversial Blockbuster: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 20-135, July 2020. (Revised May 2024.)
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