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January 2025
Teaching Note

Vytal: Packaging-as-a-Service

By: George Serafeim, Michael W. Toffel and Stacy Straaberg

Teaching Note for HBS Case No. 124-007. The Germany-based startup Vytal operated the largest digital-native reusable packaging-as-a-service network globally, having raised nearly €15 million, established a large network of restaurant partners, and prevented the use of... View Details

2024
Book

The Everything Token: How NFTs and Web3 Will Transform the Way We Buy, Sell, and Create

By: Steve Kaczynski and Scott Duke Kominers

We demystify the coming digital revolution, showing how NFTs will transform our online and offline interactions.

NFTs aren’t just pictures on the internet, or a fad that has come and gone. Rather, they’re a new technology for creating digital assets and... View Details

Find at Harvard

November 2023 (Revised January 2024)
Case

Bridgit: Persevere or Pivot?

By: Reza Satchu and Patrick Sanguineti

In late 2012, Mallorie Brodie and Lauren Lake, two young women in their final year of college, founded Bridgit, a technology startup that developed solutions to simplify vital but laborious processes within the construction industry. In the Fall of 2013, after months... View Details

Keywords: Entrepreneur; Founder; Co-founders; Women Executives; Pivot; Startup; Business Model; Business Startups; Entrepreneurship; Applications and Software; Product Launch; Research and Development; Competition; Technology Industry; Technology Industry; United States; Canada

November 2023 (Revised April 2024)
Case

Khanmigo: Revolutionizing Learning with GenAI

By: William A. Sahlman, Allison M. Ciechanover and Emily Grandjean

Already a leader in the edtech space since its 2008 launch, Khan Academy was now one of the first edtech organizations to embrace generative artificial intelligence ("genAI"). In March 2023, Khan Academy began beta testing Khanmigo, a genAI “guide” and tutor built with... View Details

Keywords: Technology Adoption; Leading Change; Entrepreneurship; Risk and Uncertainty; Education; AI and Machine Learning; Corporate Social Responsibility and Impact; Technology Industry; Technology Industry; United States; San Francisco

November 2023
Case

Chai Point

By: Rembrand Koning, Daniel W. Elfenbein and Kanika Jain

Chai Point was an Indian food and beverage company focused on chai. It started in 2010 as a retail store network but soon expanded to corporate offices by developing an IoT-enabled automatic tea and filter coffee machine. By 2023, Chai Point had 170 stores and 5000... View Details

Keywords: Entrepreneurship; Food; Resource Allocation; Vertical Integration; Expansion; Technology Industry; Technology Industry; Technology Industry; India

November 2023
Article

Open Source Software and Global Entrepreneurship

By: Nataliya Langburd Wright, Frank Nagle and Shane Greenstein

This is the first study to consider the relationship between open source software (OSS) and entrepreneurship around the globe. This study measures whether country-level participation on the GitHub OSS platform affects the founding of innovative ventures, and where it... View Details

Keywords: Entrepreneurship; Applications and Software; Business Ventures; Development Economics; Innovation and Invention; Global Range

October 2023 (Revised March 2024)
Case

KOKO Networks: Bridging Energy Transition and Affordability with Carbon Financing

By: George Serafeim, Siko Sikochi and Namrata Arora

The problem was massive: two million hectares of African forests were lost annually to charcoal production for cooking, an area equivalent to 13 times Greater London, resulting in one billion tons of carbon emissions yearly. At the same time, an estimated 700,000... View Details

Keywords: Clean Tech; Digital; Carbon Credits; Carbon Offsetting; Climate Change; Entrepreneurship; Energy Sources; Environmental Sustainability; Health; Market Design; Business Startups; Transition; Environmental Regulation; Policy; Energy Industry; Consumer Products Industry; Africa; Kenya; Rwanda

October 2023 (Revised April 2024)
Case

TetraScience: Unlocking the Power of Scientific Data

By: Satish Tadikonda and William Marks

After pivoting from a focus on hardware to a focus on scientific data, TetraScience, led by veteran SaaS executive, Patrick Grady and Founder Spin Wang, has embarked on a journey from nearly cash-out to a player in the scientific data management space. This case... View Details

Keywords: Business Model; Change Management; Entrepreneurship; Information Management; Business Strategy; Market Entry and Exit; Information Technology Industry

October 2023 (Revised November 2023)
Case

Rheaply: Circularity For Every Business

By: Rembrand Koning and Alicia Dadlani

In March 2023, Garry Cooper, cofounder and CEO of Chicago-based Rheaply, needed to demonstrate that Rheaply’s expanded vision could translate into building cash flows and metrics needed to raise a Series B and turn the business into a model for financial and... View Details

Keywords: Business Startups; Social Entrepreneurship; Technological Innovation; Environmental Sustainability; Entrepreneurial Finance; Technology Industry; Technology Industry; United States; Illinois; Chicago

October 2023
Supplement

Rheaply: Circularity For Every Business Supplement 2

By: Rembrand Koning and Alicia Dadlani

Pitch deck explaining the later vision of the company that was presented by the CEO to potential investors. View Details

Keywords: Business Startups; Social Entrepreneurship; Entrepreneurial Finance; Mission and Purpose; Technology Industry; Technology Industry; United States; Illinois; Chicago

October 2023 (Revised March 2024)
Case

Fantuan

By: Feng Zhu and David Lane

In 2023, CEO Randy Wu was considering the optimal growth strategy for Fantuan, a restaurant food delivery platform that had expanded from its 2014 founding in Vancouver, Canada to serve the Chinese demand for Asian cuisine in urban markets across Australia, Canada, the... View Details

Keywords: Business Startups; Customer Focus and Relationships; Diasporas; Entrepreneurship; Digital Platforms; Growth Management; Business Strategy; Diversification; Expansion; Growth and Development Strategy; Service Industry; Food and Beverage Industry; United States; Canada; United Kingdom; Australia

October 2023
Case

Fixie and Conversational AI Sidekicks

By: Jeffrey J. Bussgang and Carin-Isabel Knoop

In March 2023, Fixie Co-Founder and Chief Architect Matt Welsh and co-founders had the kind of meeting no founders want to have. The president of leading artificial intelligence (AI) research and deployment firm OpenAI, which had catapulted into fame with its ChatGPT... View Details

Keywords: Large Language Model; Entrepreneurship; Decision Choices and Conditions; AI and Machine Learning; Technological Innovation; Competitive Strategy; Technology Industry; United States

October 2023 (Revised November 2023)
Case

Recycle & Re-Match: The Future of Soccer Turfs

By: George Serafeim, Lena Duchene and Carlota Moniz

By August 2023, Re-Match, an artificial turf waste-to-value company, had operations in Denmark and the Netherlands and had recycled over 160,000 tons of waste and plastic fiber. With recent capital injection from the VC firm Verdane and a dual revenue business model,... View Details

2025
Working Paper

Bringing Science to Market: Knowledge Foundations, Inventor-Founders, and Performance

By: Justine Boudou and Maria Roche

In this paper, we examine how a startup’s knowledge foundations—embedded in its core technology—influence its performance in the exit market. Using a dataset of 1,006 biomedicine startups founded between 2005 and 2015, we focus on two key factors: (1) the degree of... View Details

Keywords: Firm Performance; Knowledge Foundations; Exits; Academic Startups; Inventor-founder; Specialized Scientific Knowledge; Competitive Advantage; Value Creation; Research; Information Publishing; Business Startups; Entrepreneurship

September 2023 (Revised November 2023)
Case

Seeds of Innovation: GALY's Quest to Cultivate the Future of Agriculture in the Lab

By: George Serafeim and Michael Norris

In 2023, Luciano Bueno, CEO and founder of plant cell culture agriculture company GALY, was considering the best path forward for his company as he planned to pitch Series B investors. GALY, founded in 2019, aimed to produce cotton and other crops from cells grown in... View Details

Keywords: Business Model; Green Technology; Goods and Commodities; Growth and Development Strategy; Science-Based Business; Entrepreneurship; Plant-Based Agribusiness; Business Startups; Decisions; Technological Innovation; Production; Technology Industry; Technology Industry; Boston; Sao Paulo

September 2023
Case

Ada: Cultivating Investors

By: Reza Satchu and Patrick Sanguineti

Mike Murchison, co-founder and CEO of Ada, has an enviable dilemma. Launched in 2016 by Murchison and his co-founder David Hariri, Ada is an AI-native company that aims to revolutionize how businesses approach customer service. The company has already attracted a buzz,... View Details

Keywords: Founder; Fundraising; Business Startups; Decisions; Entrepreneurship; Venture Capital; AI and Machine Learning; Technology Industry

September 2023 (Revised December 2023)
Case

TetraScience: Noise and Signal

By: Thomas R. Eisenmann and Tom Quinn

In 2019, TetraScience CEO “Spin” Wang needed advice. Five years earlier, he had cofounded a startup that saw early success with a hardware product designed to help laboratory scientists in the biotechnology and pharmaceutical spaces more easily collect data from... View Details

Keywords: Entrepreneurship; Business Growth and Maturation; Business Organization; Restructuring; Forecasting and Prediction; Digital Platforms; Analytics and Data Science; AI and Machine Learning; Organizational Structure; Network Effects; Competitive Strategy; Biotechnology Industry; Pharmaceutical Industry; United States; Boston

August 2023
Case

Beamery: Using Skills and AI to Modernize HR

By: Boris Groysberg, Alexis Lefort, Susan Pinckney and Carolina Bartunek

Unicorn human relationships startup Beamery evaluates it's growth versus depth strategy as its strategic partners and customers could become future competitors in a quickly changing AI based human resources and talent management industry View Details

August 2023
Case

Kariyer.net: Recruiting AI

By: Shunyuan Zhang, Fares Khrais and Namrata Arora

In 2017, Fatih Uysal (AMP 2021) became CEO of Kariyer.net. By then, the business was already the industry leading online job board in Turkey. However, faced with stalling growth, a turbulent macroenvironment, and growing competition from international players, Uysal... View Details

August 2023 (Revised August 2023)
Case

Sky Therapeutics: Innovating in Digital Therapeutics

By: Satish Tadikonda, Olivia Reszczynski and William Marks

Shad Faraz and Alex Youssef were intrigued by the opportunities in the relatively new area of Digital Therapeutics. Despite initial successes, early entrants had struggled with reimbursement and revenue-predictability challenges. However, venture investors still... View Details

Keywords: Business Startups; Entrepreneurship; Mission and Purpose; Technology Industry; Technology Industry

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