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- All HBS Web
(206)
- Faculty Publications (91)
- March 2008 (Revised April 2008)
- Case
Corning: 156 Years of Innovation
By: H. Kent Bowen and Courtney Purrington
The executive team at Corning has committed to double the rate of new business creation per decade, while at the same time growing the company's current businesses, including glass substrates for LCD displays. Their strategy, built on more than 150 years of successful... View Details
Keywords: Innovation Leadership; Resource Allocation; Product Development; Research and Development; Science-Based Business; Industrial Products Industry
Bowen, H. Kent, and Courtney Purrington. "Corning: 156 Years of Innovation." Harvard Business School Case 608-108, March 2008. (Revised April 2008.)
- March 2008
- Case
Novartis AG: Science-Based Business
By: H. Kent Bowen and Courtney Purrington
Novartis is a science-based drug company, which has important implications for its business strategy. It is one of the largest pharmaceutical companies in the world with over $38B in sales in 2007. Pharmaceuticals account for slightly over $24B of that total. In 2007,... View Details
Keywords: Innovation and Invention; Resource Allocation; Product Development; Partners and Partnerships; Research and Development; Science-Based Business; Pharmaceutical Industry
Bowen, H. Kent, and Courtney Purrington. "Novartis AG: Science-Based Business." Harvard Business School Case 608-136, March 2008.
- February 2008 (Revised August 2008)
- Case
EXACT Sciences Corp.: Commercializing a Diagnostic Test
This case addresses the challenges of commercializing molecular diagnostics. Along the way, it explains the technology, payment system, and the measures used to assess the value of a diagnostic test. View Details
Keywords: Health Testing and Trials; Genetics; Science-Based Business; Commercialization; Biotechnology Industry
Herzlinger, Regina E. "EXACT Sciences Corp.: Commercializing a Diagnostic Test." Harvard Business School Case 308-090, February 2008. (Revised August 2008.)
- September 2007 (Revised May 2009)
- Case
Syndexa and Technology Transfer at Harvard University
By: Richard G. Hamermesh and David Kiron
Gokhan Hotamisligil is a star researcher at Harvard School of Public Health who has made groundbreaking discoveries linking fat cells, inflammation, and diabetes. He now wants to form a company to commercialize these discoveries. At the same time, Isaac Kohlberg, the... View Details
Keywords: Business Startups; Higher Education; Entrepreneurship; Innovation and Invention; Intellectual Property; Rights; Agreements and Arrangements; Science-Based Business; Commercialization; Biotechnology Industry; Health Industry
Hamermesh, Richard G., and David Kiron. "Syndexa and Technology Transfer at Harvard University." Harvard Business School Case 808-073, September 2007. (Revised May 2009.)
- February 2007 (Revised April 2010)
- Case
Wyeth Pharmaceuticals: Spurring Scientific Creativity with Metrics
By: Robert S. Huckman, Gary P. Pisano and Mark Rennella
Describes the reorganization of the drug discovery organization at Wyeth Pharmaceuticals and focuses on the decisions to: (1) centralize decision-making within drug discovery and (2) institute numerical metrics--jointly affecting all R&D scientists--for the progression... View Details
Keywords: Decision Making; Measurement and Metrics; Business Processes; Organizational Structure; Research and Development; Science-Based Business; Creativity; Pharmaceutical Industry
Huckman, Robert S., Gary P. Pisano, and Mark Rennella. "Wyeth Pharmaceuticals: Spurring Scientific Creativity with Metrics." Harvard Business School Case 607-008, February 2007. (Revised April 2010.)
- 2006
- Book
Science Business: The Promise, the Reality, and the Future of Biotech
By: Gary P. Pisano
Why has the biotechnology industry failed to perform up to expectations—despite all its promise? In Science Business, Gary P. Pisano answers this question by providing an incisive critique of the industry. Pisano not only reveals the underlying causes of... View Details
Pisano, Gary P. Science Business: The Promise, the Reality, and the Future of Biotech. Boston: Harvard Business School Press, 2006.
- June 2006 (Revised April 2007)
- Case
BioScale
By: H. Kent Bowen and Bradley R. Staats
In 2004, Mark Lundstrom must decide on a funding method and strategic approach for BioScale, a biotechnology company that he founded. BioScale has developed a microchip-based bioanalytical platform that can be used to detect very small concentrations of cells, viruses,... View Details
Keywords: Entrepreneurship; Science-Based Business; Capital; Financing and Loans; Partners and Partnerships; Biotechnology Industry
Bowen, H. Kent, and Bradley R. Staats. "BioScale." Harvard Business School Case 606-100, June 2006. (Revised April 2007.)
- May 2006 (Revised June 2006)
- Case
Codon Devices
By: Joseph B. Lassiter III and David Kiron
In December 2005, 40-year-old John Danner was about to make his first presentation to the board of directors of Codon Devices, a one-year-old biotechnology start-up based in Cambridge, Massachusetts. After a month as the company's CEO, Danner was prepared to lay out... View Details
Keywords: Strategic Planning; Venture Capital; Intellectual Property; Governing and Advisory Boards; Genetics; Competitive Advantage; Science-Based Business; Business Startups; Growth and Development Strategy; Biotechnology Industry; Cambridge
Lassiter, Joseph B., III, and David Kiron. "Codon Devices." Harvard Business School Case 806-198, May 2006. (Revised June 2006.)
- May 2006
- Case
A123Systems
By: H. Kent Bowen, Kenneth P Morse and Douglass Cannon
A 123Systems was a young company that was founded on basic materials science research at the Massachusetts Institute of Technology. A co-founder of the company, Yet-Ming Chiang, was a full professor at MIT and served as scientific adviser. Intellectual property based... View Details
Keywords: Intellectual Property; Business Startups; Research and Development; Commercialization; Technological Innovation; Science-Based Business; Product Development; Battery Industry; Electronics Industry; Massachusetts
Bowen, H. Kent, Kenneth P Morse, and Douglass Cannon. "A123Systems." Harvard Business School Case 606-114, May 2006.
- October 2004 (Revised March 2005)
- Case
Langer Lab, The: Commercializing Science
By: H. Kent Bowen, Alex Kazaks, Ayr Muir-Harmony and Bryce LaPierre
Professor Robert Langer's laboratory at MIT is the source of an unusually large number of published papers, patents, and technology licenses to start-up and established companies in the biomedical industry. Explores Langer's leadership and other factors that create a... View Details
Keywords: Entrepreneurship; Technological Innovation; Business Startups; Research and Development; Patents; Innovation Leadership; Science-Based Business; Commercialization; Biotechnology Industry; Education Industry
Bowen, H. Kent, Alex Kazaks, Ayr Muir-Harmony, and Bryce LaPierre. "Langer Lab, The: Commercializing Science." Harvard Business School Case 605-017, October 2004. (Revised March 2005.)
- July 2004 (Revised March 2006)
- Case
RosettaNet and ebXML: Betting on the Right eBusiness Standard
By: F. Warren McFarlan and Veronika Belokhvostova
A major enterprise software company must select which technologies to support, based on their long-term and short-term viability and benefits. The protagonist is involved in the release of the B2B integration component of major enterprise software whose purpose is to... View Details
Keywords: Communication Technology; Customer Focus and Relationships; Markets; Standards; Science-Based Business; Situation or Environment; Applications and Software; Technology Adoption; Information Technology Industry
McFarlan, F. Warren, and Veronika Belokhvostova. "RosettaNet and ebXML: Betting on the Right eBusiness Standard." Harvard Business School Case 305-006, July 2004. (Revised March 2006.)
- November 2002 (Revised June 2003)
- Case
Monsanto: Leadership in a New Environment
By: Ray A. Goldberg, James Weber and James M Beagle
Monsanto is the biotechnology leader in agriculture. How does it use its leadership in Round Up to fund long-term research and development in biotechnology that is acceptable to the priority system of consumers in different parts of the world? Includes color exhibits. View Details
Keywords: Research and Development; Science-Based Business; Food; Business or Company Management; Agribusiness; Industry Growth; Customer Focus and Relationships; Globalization; Leadership; Biotechnology Industry; Agriculture and Agribusiness Industry; United States
Goldberg, Ray A., James Weber, and James M Beagle. "Monsanto: Leadership in a New Environment." Harvard Business School Case 903-419, November 2002. (Revised June 2003.)
- November 2001
- Case
Aventis CropScience and StarLink Corn
By: Ray A. Goldberg and James M Beagle
Aventis CropScience responds to the discovery of an unapproved corn variety in food supplies and draws lessons for the company, industry, and governments. View Details
- 2001
- Chapter
Transforming Life, Transforming Business: The Life Science Revolution
By: Juan Enriquez and Ray A. Goldberg
Keywords: Science-Based Business; Organizational Change and Adaptation; Human Needs; Welfare; Transformation
Enriquez, Juan, and Ray A. Goldberg. "Transforming Life, Transforming Business: The Life Science Revolution." In The Digital Enterprise: How To Reshape Your Business For A Connected World, edited by Nicholas G. Carr. Boston: Harvard Business School Press, 2001.
- 2001
- Chapter
A Business Manager's Approach to Climate Change
By: Forest Reinhardt and Kimberly O'Neill Packard
Reinhardt, Forest, and Kimberly O'Neill Packard. "A Business Manager's Approach to Climate Change." In Climate Change: Science, Strategies, & Solutions, edited by Eileen Claussen. Leiden: Brill Academic Publishers, 2001.
- January 2001
- Case
Abgenix and the XenoMouse
By: Robert J. Dolan
Abgenix has a unique method for generating antibodies useful in treating a number of diseases, including cancer. In early 2000, the company's cancer has performed very well in animal testing and is moving to early stage human testing. Abgenix must decide whether to... View Details
Keywords: Product Development; Marketing Strategy; Health Testing and Trials; Risk and Uncertainty; Technological Innovation; Innovation Strategy; Science-Based Business; Biotechnology Industry
Dolan, Robert J. "Abgenix and the XenoMouse." Harvard Business School Case 501-061, January 2001.
- 2001
- Chapter
Publicly Funded Science and the Productivity of the Pharmaceutical Industry
By: Rebecca Henderson and Ian Cockburn
U.S. taxpayers funded $14.8 billion of health related research last year, four times the amount that was spent in 1970 in real terms. In this paper we evaluate the impact of these huge expenditures on the technological performance of the pharmaceutical industry. While... View Details
Keywords: Public Sector; Science-Based Business; Research and Development; Sovereign Finance; Pharmaceutical Industry
Henderson, Rebecca, and Ian Cockburn. "Publicly Funded Science and the Productivity of the Pharmaceutical Industry." In Innovation Policy and the Economy, Volume 1, edited by Adam B. Jaffe, Josh Lerner, and Scott Stern, 1–34. MIT Press, 2001.
- December 2000
- Case
CellFor, Inc.
By: Ray A. Goldberg, Carin-Isabel Knoop, Frantz Edward Alphonse and Laure Mougeot Stroock
A new private company has developed a process to clone and multiply seeds for the forestry industry. View Details
- 1999
- Chapter
The Pharmaceutical Industry and the Revolution in Molecular Biology: Interactions Among Scientific, Institutional, and Organizational Change
By: Rebecca Henderson, Gary P. Pisano and Luigi Orsenigo
Keywords: Science-Based Business; Organizational Change and Adaptation; Transformation; Pharmaceutical Industry
Henderson, Rebecca, Gary P. Pisano, and Luigi Orsenigo. "The Pharmaceutical Industry and the Revolution in Molecular Biology: Interactions Among Scientific, Institutional, and Organizational Change." In Sources of Industrial Leadership: Studies of Seven Industries, edited by David Mowery and Richard Nelson. Cambridge University Press, 1999.
- March 1999
- Teaching Note
Conceptual Overview: "Business and the Environment," An Elective for MBA Students TN
Intended to assist faculty who teach courses on environmental management at business schools. Other people interested in the relationships between business and the environment may also find it useful. View Details