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- All HBS Web
(3,347)
- Faculty Publications (559)
- December 2023 (Revised March 2024)
- Case
Manufacturing Moderna's Future
By: Satish Tadikonda and William Marks
In 2019, Moderna faced long odds of survival having failed to develop a successful clinical program out of the vast platform technology they had built around mRNA. Nearly overnight, the company skyrocketed to success with a vaccine for COVID-19, leading to an extremely... View Details
Keywords: Health Pandemics; Health Testing and Trials; Technological Innovation; Product Development; Production; Science-Based Business; Biotechnology Industry
Tadikonda, Satish, and William Marks. "Manufacturing Moderna's Future." Harvard Business School Case 824-076, December 2023. (Revised March 2024.)
- December 2023
- Case
Raízen: Helping to Decarbonize the World?
By: Gunnar Trumbull, Pedro Levindo, Daniel Tong and Rafaella Mazza
Raízen, the world’s largest sugar and ethanol producer, strived to find ways to expand the second-generation ethanol (E2G) market, which it pioneered. The company planned to invest R$24 billion (around $4.6 billion) in 20 production plants, with a total capacity to... View Details
Keywords: Plant-Based Agribusiness; Factories, Labs, and Plants; Renewable Energy; Environmental Sustainability; Production; Expansion; Agriculture and Agribusiness Industry; Energy Industry; Brazil; Europe; North America; United States; Argentina; Paraguay
Trumbull, Gunnar, Pedro Levindo, Daniel Tong, and Rafaella Mazza. "Raízen: Helping to Decarbonize the World?" Harvard Business School Case 724-014, December 2023.
- December 2023 (Revised July 2024)
- Case
Boortmalt: The Master Maltster
By: Forest Reinhardt, Jose B Alvarez, Damien McLoughlin, Lena Duchene and Emer Moloney
By May 2023, Boortmalt was the world’s leading producer of malt, with a production capacity of 3 million tonnes, 15% of global market share, and 27 malting plants across five continents. It had recently acquired a major competitor and had sustained an EBITDA growth of... View Details
Keywords: Plant-Based Agribusiness; Mergers and Acquisitions; Talent and Talent Management; Customer Focus and Relationships; Values and Beliefs; Financing and Loans; Employee Relationship Management; Collaborative Innovation and Invention; Innovation Leadership; Knowledge Sharing; Leadership Style; Business or Company Management; Growth and Development Strategy; Growth Management; Management Style; Resource Allocation; Corporate Social Responsibility and Impact; Strategic Planning; Environmental Sustainability; Organizational Culture; Agriculture and Agribusiness Industry; Belgium; Europe
Reinhardt, Forest, Jose B Alvarez, Damien McLoughlin, Lena Duchene, and Emer Moloney. "Boortmalt: The Master Maltster." Harvard Business School Case 724-021, December 2023. (Revised July 2024.)
- December 2023
- Case
Santa Elena: Table Grape Production in Chile's Water-Challenged Regions
By: Forest Reinhardt, Jenyfeer Martinez Buitrago and Mariana Cal
In the fiscal year ending in September 2022, Santa Elena, Chile’s fifth-ranking table grape exporter, a grape producer and exporter since 1980, had exported around 3.5 million boxes (18-pound each). But, due to a 13-year-long drought that plagued table grape-growing... View Details
Keywords: Plant-Based Agribusiness; Climate Change; Environmental Regulation; Environmental Sustainability; Natural Resources; Food; Environmental Law; Problems and Challenges; Weather; Adaptation; Business Strategy; Organizational Change and Adaptation; Agriculture and Agribusiness Industry; Chile; South America; Latin America
- November 2023
- Case
Gabon Special Economic Zone
By: John Macomber and Wale Lawal
Tropical rain forest covers about 80% of the West African nation of Gabon, part of the Congo Basin and the "lungs of the world." Gabon is one of the first nations to earn revenue from carbon sequestration...as long as the rain forest remains intact. There are... View Details
Keywords: Economic Development; Forestry; Wood; Carbon Credits; Supply Chain; Economic Growth; Developing Countries and Economies; Climate Change; Environmental Sustainability; Government Administration; Business and Government Relations; Strategy; Forest Products Industry; Africa; Gabon
Macomber, John, and Wale Lawal. "Gabon Special Economic Zone." Harvard Business School Case 224-012, November 2023.
- November 2023 (Revised April 2024)
- Case
BiomX: Bringing Phage Back to the Stage
By: Paul A. Gompers, Elie Ofek, Orna Dan and Emilie Billaud
In the spring of 2023, and following the favorable results of a trial involving its phage cocktail for treating lung infections among cystic fibrosis (CF) patients, the leadership of BiomX had several critical issues to wrestle with. First, given its precarious... View Details
Keywords: Working Capital; Financing and Loans; Health Testing and Trials; Product Development; Research and Development; Science-Based Business; Commercialization; Biotechnology Industry; Pharmaceutical Industry
Gompers, Paul A., Elie Ofek, Orna Dan, and Emilie Billaud. "BiomX: Bringing Phage Back to the Stage." Harvard Business School Case 524-051, November 2023. (Revised April 2024.)
- November 2023 (Revised March 2024)
- Case
Infarm: Betting the (Indoor) Farm on Food Security
By: Elie Ofek
In the summer of 2023, the co-founders of Infarm, a controlled environment agriculture (CEA) company, were contemplating a major pivot going forward. While Infarm had successfully shown it could grow over 75 products—mainly herbs, leafy greens and mushrooms—in modular... View Details
Keywords: Plant-Based Agribusiness; Business Model; Market Entry and Exit; Science-Based Business; Business Strategy; Transition; Agriculture and Agribusiness Industry; Europe; North America; Toronto; Northeastern United States
Ofek, Elie. "Infarm: Betting the (Indoor) Farm on Food Security." Harvard Business School Case 524-043, November 2023. (Revised March 2024.)
- October 2023 (Revised April 2024)
- Case
Veeva Systems: The Next Frontier
By: Satish Tadikonda and William Marks
Born out of a desire to bring technological advances in enterprise software into the healthcare vertical, Peter Gassner and Matt Wallach founded Veeva to bring life sciences companies into the digital age for data management in both the commercial and R&D sectors. Over... View Details
Keywords: Business Model; Governance Compliance; Applications and Software; Growth Management; Expansion; Technology Industry
Tadikonda, Satish, and William Marks. "Veeva Systems: The Next Frontier." Harvard Business School Case 824-074, October 2023. (Revised April 2024.)
- October 2023 (Revised March 2024)
- Case
KOKO Networks: Bridging Energy Transition and Affordability with Carbon Financing
By: George Serafeim, Siko Sikochi and Namrata Arora
The problem was massive: two million hectares of African forests were lost annually to charcoal production for cooking, an area equivalent to 13 times Greater London, resulting in one billion tons of carbon emissions yearly. At the same time, an estimated 700,000... View Details
Keywords: Clean Tech; Digital; Carbon Credits; Carbon Offsetting; Climate Change; Entrepreneurship; Energy Sources; Environmental Sustainability; Health; Market Design; Business Startups; Transition; Environmental Regulation; Policy; Energy Industry; Consumer Products Industry; Africa; Kenya; Rwanda
Serafeim, George, Siko Sikochi, and Namrata Arora. "KOKO Networks: Bridging Energy Transition and Affordability with Carbon Financing." Harvard Business School Case 124-022, October 2023. (Revised March 2024.)
- October 2023 (Revised November 2023)
- Case
Rheaply: Circularity For Every Business
By: Rembrand Koning and Alicia Dadlani
In March 2023, Garry Cooper, cofounder and CEO of Chicago-based Rheaply, needed to demonstrate that Rheaply’s expanded vision could translate into building cash flows and metrics needed to raise a Series B and turn the business into a model for financial and... View Details
Keywords: Business Startups; Social Entrepreneurship; Technological Innovation; Environmental Sustainability; Entrepreneurial Finance; Technology Industry; Green Technology Industry; United States; Illinois; Chicago
Koning, Rembrand, and Alicia Dadlani. "Rheaply: Circularity For Every Business." Harvard Business School Case 724-351, October 2023. (Revised November 2023.)
- October 2023
- Case
Driving Sustainability at AB InBev
By: Ethan Rouen and Antonio Manuel Oftelie
It was the height of the summer in 2022, and Michel Doukeris, the CEO of Anheuser-Busch InBev (AB InBev), and Peter Kraemer, the company’s Chief Supply Officer, gazed across the vast desert surrounding Zacatecas, Mexico. They were visiting their Grupo Modelo Brewery,... View Details
Keywords: Innovation; Transformation; Decisions; Environmental Sustainability; Leading Change; Growth Management; Business Model; Food and Beverage Industry; Mexico
Rouen, Ethan, and Antonio Manuel Oftelie. "Driving Sustainability at AB InBev." Harvard Business School Case 124-037, October 2023.
- October 2023 (Revised November 2023)
- Case
Recycle & Re-Match: The Future of Soccer Turfs
By: George Serafeim, Lena Duchene and Carlota Moniz
By August 2023, Re-Match, an artificial turf waste-to-value company, had operations in Denmark and the Netherlands and had recycled over 160,000 tons of waste and plastic fiber. With recent capital injection from the VC firm Verdane and a dual revenue business model,... View Details
Keywords: Carbon Emissions; Carbon Abatement; Sustainability; Recycling; Waste Management; Technology; Entrepreneurial Management; Business Growth and Maturation; Business Model; Decisions; Energy Conservation; Investment Return; Profit; Technological Innovation; Patents; Growth and Development Strategy; Market Entry and Exit; Digital Platforms; Wastes and Waste Processing; Business Strategy; Competition; Expansion; Technology Adoption; Sports; Environmental Sustainability; Entrepreneurship; Green Technology Industry; Service Industry; Manufacturing Industry; Rubber Industry; Sports Industry; Denmark; Netherlands; France; United States; Pennsylvania; Europe
Serafeim, George, Lena Duchene, and Carlota Moniz. "Recycle & Re-Match: The Future of Soccer Turfs." Harvard Business School Case 124-032, October 2023. (Revised November 2023.)
- October 2023 (Revised June 2024)
- Case
Revvity: A Symbol of Change
By: Satish Tadikonda and William Marks
After selling the PerkinElmer name and several ancillary business units, Prahlad Singh (CEO) and his team at the newly christened Revvity faced a challenge on how best to capitalize on the opportunities ahead for the business and emerge as winners within the Life... View Details
Tadikonda, Satish, and William Marks. "Revvity: A Symbol of Change." Harvard Business School Case 824-071, October 2023. (Revised June 2024.)
- 2025
- Working Paper
Bringing Science to Market: Knowledge Foundations, Inventor-Founders, and Performance
By: Justine Boudou and Maria Roche
In this paper, we examine how a startup’s knowledge foundations—embedded in its
core technology—influence its performance in the exit market. Using a dataset of 1,006
biomedicine startups founded between 2005 and 2015, we focus on two key factors: (1)
the degree of... View Details
Keywords: Firm Performance; Knowledge Foundations; Exits; Academic Startups; Inventor-founder; Specialized Scientific Knowledge; Competitive Advantage; Value Creation; Research; Information Publishing; Business Startups; Entrepreneurship
Boudou, Justine, and Maria Roche. "Bringing Science to Market: Knowledge Foundations, Inventor-Founders, and Performance." Harvard Business School Working Paper, No. 24-021, October 2023. (Revised February 2025.)
- September 2023 (Revised January 2024)
- Case
AB InBev: Brewing Up Forecasts during COVID-19
By: Mark Egan, C. Fritz Foley, Esel Cekin and Emilie Billaud
In July 2021, the CEO of AB InBev's European operations and his team strategized to position the company for success post-pandemic. As the world's largest beer company, boasting over 500 brands, revenue of $46 billion, and a workforce of 160,000 in 2020, AB InBev... View Details
Keywords: Beer; Forecasting; COVID-19; Decision; Forecasting and Prediction; Analytics and Data Science; Crisis Management; Decisions; Financing and Loans; Investment Return; Resource Allocation; Distribution; Production; Business Processes; Strategic Planning; Health Pandemics; Digital Transformation; Markets; Food and Beverage Industry; Belgium; Europe; Latin America; North and Central America
Egan, Mark, C. Fritz Foley, Esel Cekin, and Emilie Billaud. "AB InBev: Brewing Up Forecasts during COVID-19." Harvard Business School Case 224-020, September 2023. (Revised January 2024.)
- September 2023 (Revised November 2023)
- Case
Seeds of Innovation: GALY's Quest to Cultivate the Future of Agriculture in the Lab
By: George Serafeim and Michael Norris
In 2023, Luciano Bueno, CEO and founder of plant cell culture agriculture company GALY, was considering the best path forward for his company as he planned to pitch Series B investors. GALY, founded in 2019, aimed to produce cotton and other crops from cells grown in... View Details
Keywords: Business Model; Green Technology; Goods and Commodities; Growth and Development Strategy; Science-Based Business; Entrepreneurship; Plant-Based Agribusiness; Business Startups; Decisions; Technological Innovation; Production; Agriculture and Agribusiness Industry; Technology Industry; Boston; Sao Paulo
Serafeim, George, and Michael Norris. "Seeds of Innovation: GALY's Quest to Cultivate the Future of Agriculture in the Lab." Harvard Business School Case 124-017, September 2023. (Revised November 2023.)
- September 2023 (Revised December 2023)
- Case
TetraScience: Noise and Signal
By: Thomas R. Eisenmann and Tom Quinn
In 2019, TetraScience CEO “Spin” Wang needed advice. Five years earlier, he had cofounded a startup that saw early success with a hardware product designed to help laboratory scientists in the biotechnology and pharmaceutical spaces more easily collect data from... View Details
Keywords: Entrepreneurship; Business Growth and Maturation; Business Organization; Restructuring; Forecasting and Prediction; Digital Platforms; Analytics and Data Science; AI and Machine Learning; Organizational Structure; Network Effects; Competitive Strategy; Biotechnology Industry; Pharmaceutical Industry; United States; Boston
Eisenmann, Thomas R., and Tom Quinn. "TetraScience: Noise and Signal." Harvard Business School Case 824-024, September 2023. (Revised December 2023.)
- September 13, 2023
- Article
How the Best Chief Data Officers Create Value
By: Suraj Srinivasan and Robin Seibert
Despite the rapidly increasing prominence of data and analytics functions, the majority of chief data officers (CDOs) fail to value and price the business outcomes created by their data and analytics capabilities. It comes as no surprise then that many CDOs fall behind... View Details
Srinivasan, Suraj, and Robin Seibert. "How the Best Chief Data Officers Create Value." Harvard Business Review (website) (September 13, 2023).
- September 2023 (Revised April 2024)
- Case
Atomwise: Strategic Opportunities in AI for Pharma
By: Satish Tadikonda
Abraham Heifets and his co-founder, Izhar Wallach, had founded Atomwise to develop i) an AI engine to transform drug discovery by creating better medicines faster, and ii) a machine learning-based discovery engine that combined the power of convolutional neural... View Details
Keywords: Business Model; Business Startups; AI and Machine Learning; Science-Based Business; Technological Innovation; Biotechnology Industry; Pharmaceutical Industry
Tadikonda, Satish. "Atomwise: Strategic Opportunities in AI for Pharma." Harvard Business School Case 824-043, September 2023. (Revised April 2024.)
- September 2023
- Teaching Note
Apple’s iPhone Revolution: Pioneering the Circular Economy
By: George Serafeim
Teaching Note for HBS Case 123-089. The case describes the Trade-In system for iPhones that allow iPhones to be refurbished and reused or to be recycled. The case provides information for the students to analyze the financial attractiveness of the Trade-In system and... View Details