Publications

October 1997 (Revised September 2003)
Case

Eli Lilly and Company: Drug Development Strategy (A)

By: Stefan H. Thomke, Ashok Nimgade and Paul Pospisil

Describes how Eli Lilly and Co. tries to accelerate its new drug development process with the aid of "combinatorial chemistry"--a rapidly emerging and revolutionary approach to preclinical drug discovery. The product manager of a potential blockbuster migraine drug... View Details

Keywords: Chemicals; Finance; Innovation and Invention; Time Management; Markets; Product Development; Organizations; Business Processes; Problems and Challenges; Business and Stakeholder Relations; Competition; Pharmaceutical Industry

1997
Chapter

Discussion of "Microeconomic Policy, Technological Change, and Small Business" by Edwin Mansfield

By: Joshua Lerner

Edwin Mansfield’s thoughtful review of the literature on the economics of technological change raises a variety of interesting issues, far too many to address in a few pages. Consequently I will focus my discussion on the section that I found most challenging and... View Details

Keywords: Policy; Technological Innovation

19 Oct 2012
Research & Ideas

Digital Technology’s Profound Game Change for Marketers

technology is radically transforming the marketing function and the role of the marketing professional. The changes rippling through the marketing industry goes far beyond the simple mantra of "follow the eyeballs" to different... View Details

Keywords: by Jeffrey Bussgang; Advertising; Technology

March 2011
Article

Cheaper Patents

By: Tom Nicholas

The 1883 Patents Act in Britain provides perspective for modern patent policy reforms because it radically changed incentives for inventors by reducing filing fees by 84 percent. Patents increased 2.5 fold after the reform, which was evenly distributed across the... View Details

Keywords: Patents; Global Range; Distribution; Demand and Consumers; Organizational Structure; Business Processes; Innovation and Invention; Innovation and Management; Policy; Governing Rules, Regulations, and Reforms; Fluctuation; Motivation and Incentives; Distribution Industry; United States; Great Britain

04 Aug 2010
Working Paper Summaries

The Effect of Market Leadership in Business Process Innovation: The Case(s) of E-Business Adoption

Keywords: by Kristina McElheran; Technology

2024
Working Paper

Gastrointestinal Endoscopy--Without Cutting In: Case Histories of Transformational Advances

By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins

This case history describes how endoscopy transformed the diagnosis of ulcers, cancerous polyps, and other alimentary canal diseases and enabled “minimally invasive” surgeries to treat such diseases. Specifically, we chronicle how: 1) flexible glass fiber endoscopes... View Details

Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms

SSRN

21 Feb 2012
First Look

First Look: Feb. 21

discussed. Read the paper: http://www.hbs.edu/research/pdf/04-054.pdf Innovation Strategy and Entry Deterrence Authors:Ozge Turut and Elie Ofek Publication:Journal of Economics and Management Strategy (forthcoming) We model an incumbent's... View Details

Keywords: Sean Silverthorne

2022
Book

Productive Tensions: How Every Leader Can Tackle Innovation's Toughest Trade-Offs

By: Chris Bingham and Rory McDonald

Why is leading innovation in nascent business environments so distressingly hit-or-miss? More than 90% of high-potential ventures don’t reach their projected targets. Surveys show that 80% of executives consider innovation crucial to their growth strategy, but only 6%... View Details

Keywords: Growth and Development Strategy; Innovation and Management; Organizational Culture; Leadership Style; Decision Making

January 2004
Article

Corporate Venturing: The Origins of Unilever's Pregnancy Test

By: Geoffrey Jones and Alison Kraft

The relative ability of different sizes of firm and organisational designs to develop and sustain dynamic capabilities in innovation and create new businesses remains a matter of contention. While Chandler among many others has emphasised the pre-eminent role of large... View Details

Keywords: Business Ventures; Organizational Design; Technological Innovation; Business Startups; Venture Capital; Brands and Branding; Multinational Firms and Management; Product Development; Product Launch; Corporate Entrepreneurship; Great Britain

2022
Article

Missing Novelty in Drug Development

By: Joshua Krieger, Danielle Li and Dimitris Papanikolaou

We provide evidence that risk aversion leads pharmaceutical firms to underinvest in radical innovation. We introduce a new measure of drug novelty based on chemical similarity and show that firms face a risk-reward trade-off: novel drug candidates are less likely to... View Details

Keywords: Drug Development; Risk Aversion; Research and Development; Innovation and Invention; Investment; Pharmaceutical Industry

December 1998 (Revised October 2007)
Case

Tele-Communications, Inc.: Accelerating Digital Deployment

By: Thomas R. Eisenmann

The top management team at Tele-Communications, Inc. (TCI), the largest U.S. cable company, conceived and implemented a dramatic operational turnaround and a radical new technology strategy over an 18-month period beginning in late 1996. View Details

Keywords: Technological Innovation; Value Creation; Operations; Information Management; Business Strategy; Information Technology Industry; Telecommunications Industry; United States

03 Jun 2015
What Do You Think?

Is the Time Right for Self-Management?

Gary Hamel's book, The Future of Management, in which he described innovative efforts to enable employees to define their own jobs and shape their work at companies such as Google, Whole Foods Market, and W. L. Gore & Associates, Inc.... View Details

Keywords: by James Heskett; Retail

June 2016
Article

Wicked Problem Solvers: Lessons from Successful Cross-industry Teams

By: Amy C. Edmondson

Companies today increasingly rely on teams that span many industries for radical innovation, especially to solve “wicked problems.” So leaders have to understand how to promote collaboration when roles are uncertain, goals are shifting, expertise and organizational... View Details

Keywords: Groups and Teams; Leadership Style; Collaborative Innovation and Invention

Register to Read

September 1996
Case

Silicon Graphics, Inc. (B)

By: Marco Iansiti and Alan D. MacCormack

After the release of the "Challenge" computer in 1993, Silicon Graphics executives meet to discuss the follow-up project. Should they pursue an incremental improvement to the Challenge, or opt for a radically new design recently demonstrated at Stanford University? View Details

Keywords: Decisions; Technological Innovation; Management Practices and Processes; Product Development; Hardware; Computer Industry

Research Summary

Technological Change and Competitive Strategy

Richard S. Rosenbloom continues to explore issues in the strategic management of technology and the relationship between technological change and competitive strategy. He is currently investigating the histories of radical technological innovations and their... View Details

23 Aug 2006
Working Paper Summaries

Capturing Benefits from Tomorrow’s Technology in Today’s Products: The Effect of Absorptive Capacity

Keywords: by Daniel Snow; Technology

Productive Tensions: How Every Leader Can Tackle Innovation’s Toughest Trade-Offs

How leaders can recast innovation’s toughest trade-offs—efficiency vs. flexibility, consistency vs. change, product vs purpose—as productive tensions.

Why is leading innovation in today’s dynamic business environment so distressingly... View Details

April 2023 (Revised September 2023)
Case

Levels: The Remote, Asynchronous, Deep Work Management System

By: Joseph B. Fuller and George Gonzalez

Levels is a highly innovative startup in the health care space. They intend to revolutionize health by linking behavior—eating, exercise, sleeping, etc.—to changes in metabolism. They believe metabolic health can be managed through careful monitoring of changes in... View Details

Keywords: Applications and Software; Business Startups; Organizational Culture; Management Style; Technology Industry; United States

October 2006 (Revised August 2007)
Case

RKS Guitars

By: Elie Ofek, Thomas J. Steenburgh, Michael I. Norton and Kerry Herman

RKS has designed a revolutionary electric guitar and needs to decide how to best market their innovation. The iconic status of existing electric guitars, and the lack of any recent radical innovations in the category, pose challenges in securing consumer adoption. If... View Details

Keywords: Innovation and Invention; Marketing Strategy; Product Launch; Consumer Behavior; Product Design; Adoption