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February 2024
Article

Representation and Extrapolation: Evidence from Clinical Trials

By: Marcella Alsan, Maya Durvasula, Harsh Gupta, Joshua Schwartzstein and Heidi L. Williams

This article examines the consequences and causes of low enrollment of Black patients in clinical trials. We develop a simple model of similarity-based extrapolation that predicts that evidence is more relevant for decision-making by physicians and patients when it... View Details

Keywords: Representation; Racial Disparity; Health Testing and Trials; Race; Equality and Inequality; Innovation and Invention; Pharmaceutical Industry

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January 2024 (Revised June 2024)
Case

Equal Justice Initiative: Mercy, Truth and Dignity

By: V. Kasturi Rangan, Gerald Chertavian and Brittany Logan

In 1989, the Equal Justice Initiative was established as a non-profit, public interest law firm by Harvard Law School graduate, Bryan Stevenson.

EJI provides legal assistance to condemned prisoners, people wrongly convicted or unfairly sentenced, children in... View Details

Keywords: Equality and Inequality; Nonprofit Organizations; Mission and Purpose; Growth and Development Strategy; Social Issues; Race

January 2024 (Revised August 2024)
Case

Essex County Community Foundation: Pivot to Systems Philanthropy

By: V. Kasturi Rangan, Brian Trelstad and Courtney Han

2023 marked five years of the Essex County Community Foundation (ECCF)’s “systems philanthropy” approach to grantmaking. Located in northeastern Massachusetts, the community foundation served 800,000 residents across 34 cities and towns that varied widely by... View Details

Keywords: Philanthropy and Charitable Giving; Reputation; Civil Society or Community; Social Issues; Alignment; Nonprofit Organizations; Business and Stakeholder Relations; Collaborative Innovation and Invention; Leading Change; Massachusetts

January 2024
Supplement

Winning Business at Russell Reynolds

By: Ethan Bernstein and Cara Mazzucco

In an effort to make compensation drive collaboration, Russell Reynolds Associates’ (RRA) CEO Clarke Murphy sought to re-engineer the bonus system for his executive search consultants in 2016. As his HR analytics guru, Kelly Smith, points out, that risks upsetting—and... View Details

Keywords: Restructuring; Talent and Talent Management; Compensation and Benefits; Growth and Development Strategy; Organizational Change and Adaptation; Organizational Culture; Performance Evaluation; Motivation and Incentives; Consulting Industry

January 2024 (Revised June 2024)
Supplement

School of Rock: Tuning into Structured Empowerment (B)

By: Tatiana Sandino, Jeffrey Rayport, Samuel Grad and Stacy Straaberg

In September 2022, Price and his team evaluated the past year’s strategies to increase Method App adoption and discussed new initiatives to consider. View Details

Keywords: Business Strategy; Technology Adoption; Education Industry; Music Industry; United States; Massachusetts

January 2024
Article

A Cost Model for a Low Threshold Clinic Treating Opioid Use Disorder

By: Sarah E. Wakeman, Elizabeth Powell, Syed Shehab, Grace Herman, Laura Kehoe and Robert S. Kaplan

The US fee-for-service payment system under-reimburses clinics offering access to comprehensive treatments for opioid use disorder (OUD). The funding shortfall limits a clinic’s ability to expand and improve access, especially for socially marginalized patients with... View Details

Keywords: Health Care and Treatment; Cost; Equality and Inequality; Health Industry

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2024
Book

The Everything Token: How NFTs and Web3 Will Transform the Way We Buy, Sell, and Create

By: Steve Kaczynski and Scott Duke Kominers

We demystify the coming digital revolution, showing how NFTs will transform our online and offline interactions.

NFTs aren’t just pictures on the internet, or a fad that has come and gone. Rather, they’re a new technology for creating digital assets and... View Details

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2023
Working Paper

New Facts and Data about Professors and Their Research

By: Kyle Myers, Wei Yang Tham, Jerry Thursby, Marie Thursby, Nina Cohodes, Karim R. Lakhani, Rachel Mural and Yilun Xu

We introduce a new survey of professors at roughly 150 of the most research-intensive institutions of higher education in the US. We document seven new features of how research-active professors are compensated, how they spend their time, and how they perceive their... View Details

Keywords: Research; Higher Education; Compensation and Benefits; Measurement and Metrics; Equality and Inequality; Performance Productivity

December 2023
Case

TikTok: The Algorithm Will See You Now

By: Shikhar Ghosh and Shweta Bagai

In a world where attention is a scarce commodity, this case explores the meteoric rise of TikTok—an app that transformed from a niche platform for teens into the most visited domain by 2021—surpassing even Google. Its algorithm was a sophisticated mechanism for... View Details

Keywords: Social Media; Applications and Software; Disruptive Innovation; Business and Government Relations; International Relations; Cybersecurity; Culture; Technology Industry; China; United States; India

2023
Article

Benchmarking Large Language Models on CMExam—A Comprehensive Chinese Medical Exam Dataset

By: Junling Liu, Peilin Zhou, Yining Hua, Dading Chong, Zhongyu Tian, Andrew Liu, Helin Wang, Chenyu You, Zhenhua Guo, Lei Zhu and Michael Lingzhi Li

Recent advancements in large language models (LLMs) have transformed the field of question answering (QA). However, evaluating LLMs in the medical field is challenging due to the lack of standardized and comprehensive datasets. To address this gap, we introduce CMExam,... View Details

Keywords: Large Language Model; AI and Machine Learning; Analytics and Data Science; Health Industry

2023
Other Article

The Harvard USPTO Patent Dataset: A Large-Scale, Well-Structured, and Multi-Purpose Corpus of Patent Applications

By: Mirac Suzgun, Luke Melas-Kyriazi, Suproteem K. Sarkar, Scott Duke Kominers and Stuart Shieber

Innovation is a major driver of economic and social development, and information about many kinds of innovation is embedded in semi-structured data from patents and patent applications. Though the impact and novelty of innovations expressed in patent data are difficult... View Details

Keywords: USPTO; Natural Language Processing; Classification; Summarization; Patent Novelty; Patent Trolls; Patent Enforceability; Patents; Innovation and Invention; Intellectual Property; AI and Machine Learning; Analytics and Data Science

November 2023 (Revised June 2025)
Case

Aviva plc: Examining Net Zero

By: Peter Tufano, Brian Trelstad and Matteo Gasparini

The board of Aviva Plc, one of the world’s largest insurers, must review its climate risk exposures and evaluate next steps. Risk experts at the firm have conducted a robust set of analyses prepared for its regulator, the Bank of England, simulating how various climate... View Details

Keywords: Analysis; Climate Change; Insurance; Governing and Advisory Boards; Risk Management; Adaptation; Financial Services Industry; Insurance Industry; Europe; United Kingdom

2023
Working Paper

Coordinated R&D Programs and the Creation of New Industries

By: Daniel P. Gross and Maria P. Roche

Complex systems technologies—including “deep tech”—are prone to numerous frictions that stymie commercial development. Yet technologies with these features underpin some of the most valuable industries of the past century. We examine how large, mission-oriented... View Details

Keywords: Research and Development; Policy; Business and Government Relations; Technological Innovation; Collaborative Innovation and Invention

November 2023 (Revised April 2024)
Case

Khanmigo: Revolutionizing Learning with GenAI

By: William A. Sahlman, Allison M. Ciechanover and Emily Grandjean

Already a leader in the edtech space since its 2008 launch, Khan Academy was now one of the first edtech organizations to embrace generative artificial intelligence ("genAI"). In March 2023, Khan Academy began beta testing Khanmigo, a genAI “guide” and tutor built with... View Details

Keywords: Technology Adoption; Leading Change; Entrepreneurship; Risk and Uncertainty; Education; AI and Machine Learning; Corporate Social Responsibility and Impact; Education Industry; Technology Industry; United States; San Francisco

October 2023 (Revised March 2024)
Case

KOKO Networks: Bridging Energy Transition and Affordability with Carbon Financing

By: George Serafeim, Siko Sikochi and Namrata Arora

The problem was massive: two million hectares of African forests were lost annually to charcoal production for cooking, an area equivalent to 13 times Greater London, resulting in one billion tons of carbon emissions yearly. At the same time, an estimated 700,000... View Details

October 2023 (Revised January 2024)
Case

Ball: EVA Driving the World's Leading Can Manufacturer (A)

By: Jonas Heese and Susan Pinckney

The case describes Ball’s multi decade history of using Economic Value Added to drive decision making and workforce compensation. In 2016, the company acquired Rexam PLC and became the world’s leading metal beverage container company. Consumer demand for varied... View Details

October 2023
Case

Shredder Setups or Straightlining into Risk?: Investing in What You Love

By: Lauren Cohen and Grace Headinger

Bob Hall, President of Green Gables Partners, evaluated whether to angel invest into an up-and-coming ski brand. As the son-in-law of the founder of Vera Bradley and having retired from a lengthy career on Wall Street, Hall was well-versed in both direct investing and... View Details

Keywords: Family Office; Angel Investors; Direct Investment; Family Business; Business Growth and Maturation; Small Business; Financial Strategy; Personal Finance; Investment Portfolio; Private Equity; Decision Choices and Conditions; Risk and Uncertainty; Consumer Products Industry; Montana; United States

October 2023 (Revised March 2024)
Case

Fantuan

By: Feng Zhu and David Lane

In 2023, CEO Randy Wu was considering the optimal growth strategy for Fantuan, a restaurant food delivery platform that had expanded from its 2014 founding in Vancouver, Canada to serve the Chinese demand for Asian cuisine in urban markets across Australia, Canada, the... View Details

Keywords: Business Startups; Customer Focus and Relationships; Diasporas; Entrepreneurship; Digital Platforms; Growth Management; Business Strategy; Diversification; Expansion; Growth and Development Strategy; Service Industry; Food and Beverage Industry; United States; Canada; United Kingdom; Australia

October 2023
Case

Fixie and Conversational AI Sidekicks

By: Jeffrey J. Bussgang and Carin-Isabel Knoop

In March 2023, Fixie Co-Founder and Chief Architect Matt Welsh and co-founders had the kind of meeting no founders want to have. The president of leading artificial intelligence (AI) research and deployment firm OpenAI, which had catapulted into fame with its ChatGPT... View Details

Keywords: Large Language Model; Entrepreneurship; Decision Choices and Conditions; AI and Machine Learning; Technological Innovation; Competitive Strategy; Technology Industry; United States

September 2023 (Revised September 2023)
Teaching Note

Roche: Innovation and Access to Healthcare

By: George Serafeim

Teaching Note for HBS Case No. 123-075. In May 2022, Roche Group, one of the largest healthcare companies in the world, hosted its first investor event focused exclusively on its efforts to impact access to healthcare. While Roche had recently set an ambitious goal to... View Details

Keywords: ESG; Access To Care; Healthcare; Healthcare Access; Innovation; Social Impact; Affordable; Health Care and Treatment; Innovation and Invention; Product Development; Resource Allocation; Corporate Social Responsibility and Impact; Health Industry

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