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Show Results For
- All HBS Web
(924)
- News (120)
- Research (620)
- Events (3)
- Multimedia (3)
- Faculty Publications (248)
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- August 2003 (Revised August 2024)
- Case
Fighting the Battle of the Bulge—Evaluating Do Good/Do Well Innovations in Morbid Obesity Treatment
By: Regina E. Herzlinger and John McDonough
Many health care innovations appear successful; but fail. This is the first case in the Innovating Health Care course that investigates how to create successful health care innovations. It is part of the first module in the course. This module focuses on how to... View Details
Keywords: Three Pillars; Industry Analysis; Health Care and Treatment; Innovation and Invention; Innovation and Management; Medical Specialties; Health Industry
Herzlinger, Regina E., and John McDonough. "Fighting the Battle of the Bulge—Evaluating Do Good/Do Well Innovations in Morbid Obesity Treatment." Harvard Business School Case 304-009, August 2003. (Revised August 2024.)
- January 2008
- Article
Innovation Killers: How Financial Tools Destroy Your Capacity to Do New Things
By: Clayton M. Christensen, Stephen P. Kaufman and Willy C. Shih
Most companies aren't half as innovative as their senior executives want them to be (or as their marketing claims suggest they are). What's stifling innovation? There are plenty of usual suspects, but the authors finger three financial tools as key accomplices.... View Details
Keywords: Investment; Innovation and Management; Growth and Development Strategy; Business and Shareholder Relations; Prejudice and Bias; Value Creation
Christensen, Clayton M., Stephen P. Kaufman, and Willy C. Shih. "Innovation Killers: How Financial Tools Destroy Your Capacity to Do New Things." Special Issue on HBS Centennial. Harvard Business Review 86, no. 1 (January 2008).
- 2011
- Other Unpublished Work
From Farms to Fuel Tanks: Collective Actors and New-Venture Innovation in the U.S. Biodiesel Fuel Sector
By: Shon R. Hiatt
Little is known about the influence of collective actors on innovative technological recombinations by new ventures. Using data from U.S. biodiesel producers, I examine how the efforts of multiple collective actors (farm associations) to promote varying types of... View Details
- April 2024 (Revised November 2024)
- Case
Moderna: Pioneering a People Platform to Accelerate Science Innovation
By: Tatiana Sandino, Emil Dy and Samuel Grad
Moderna was founded in 2010 to explore how messenger ribonucleic acid (mRNA) could be used to create breakthrough medicines by encoding instructions for the body to create antibodies. When Stéphane Bancel (HBS 2000) took over in 2011, he bet on the potential of this... View Details
Keywords: Disruptive Innovation; Talent and Talent Management; Selection and Staffing; AI and Machine Learning; Digital Strategy; Innovation and Management; Leadership Development; Management Practices and Processes; Management Systems; Organizational Culture; Performance Evaluation; Alignment; Employee Relationship Management; Science-Based Business; Expansion; Pharmaceutical Industry; Biotechnology Industry; United States
Sandino, Tatiana, Emil Dy, and Samuel Grad. "Moderna: Pioneering a People Platform to Accelerate Science Innovation." Harvard Business School Case 124-091, April 2024. (Revised November 2024.)
- Article
Use of Crowd Innovation to Develop an Artificial Intelligence-Based Solution for Radiation Therapy Targeting
By: Raymond H. Mak, Michael G. Endres, Jin Hyun Paik, Rinat A. Sergeev, Hugo Aerts, Christopher L. Williams, Karim R. Lakhani and Eva C. Guinan
Importance: Radiation therapy (RT) is a critical cancer treatment, but the existing radiation oncologist work force does not meet growing global demand. One key physician task in RT planning involves tumor segmentation for targeting, which requires substantial... View Details
Keywords: Crowdsourcing; AI Algorithms; Health Care and Treatment; Collaborative Innovation and Invention; AI and Machine Learning
Mak, Raymond H., Michael G. Endres, Jin Hyun Paik, Rinat A. Sergeev, Hugo Aerts, Christopher L. Williams, Karim R. Lakhani, and Eva C. Guinan. "Use of Crowd Innovation to Develop an Artificial Intelligence-Based Solution for Radiation Therapy Targeting." JAMA Oncology 5, no. 5 (May 2019): 654–661.
- 12 Sep 2022
- Research & Ideas
When Experts Play It Too Safe: Innovation Lessons from a NASA Experiment
When evaluating whether to invest in a new idea, senior executives often rely on experts. But these advisers often favor ideas that are easy to execute over tough-to-pull-off but potentially groundbreaking plans. The risk for companies:... View Details
- May 2017
- Case
ATH Technologies: Making the Numbers
By: Robert Simons and Jennifer Packard
An exercise that takes students through five stages of growth in an entrepreneurial start-up in the medical devices industry: 1) founding, 2) growth, 3) push to profitability, 4) relocation process, and 5) takeover by new management. At each stage, students must... View Details
Keywords: Balancing Innovation And Control; Performance Evaluation; Strategy And Execution; Management Control Systems; Risk Management; Business Growth and Maturation; Business Startups; Profit; Geographic Location; Governance Controls; Innovation and Invention; Management Succession; Medical Devices and Supplies Industry
Simons, Robert, and Jennifer Packard. "ATH Technologies: Making the Numbers." Harvard Business School Case 117-012, May 2017.
- 28 Mar 2023
- Research & Ideas
The FDA’s Speedy Drug Approvals Are Safe: A Win-Win for Patients and Pharma Innovation
“The findings of our study suggest that regulatory innovation can support more efficient drug development—in particular, in settings where we have unmet medical needs. ” In the first comprehensive analysis of its kind, Harvard Business... View Details
- November 2018
- Article
Disruptive Innovation: An Intellectual History and Directions for Future Research
By: Clayton M. Christensen, Rory McDonald, Elizabeth J. Altman and Jonathan E. Palmer
The concept of disruptive innovation has gained considerable currency among practitioners despite widespread misunderstanding of its core principles. Similarly, foundational research on disruption has elicited frequent citation and vibrant debate in academic circles,... View Details
Keywords: Innovation Metrics; Systemic Industries; Technology Trajectories; Disruptive Innovation; Theory; History; Competitive Strategy; Research
Christensen, Clayton M., Rory McDonald, Elizabeth J. Altman, and Jonathan E. Palmer. "Disruptive Innovation: An Intellectual History and Directions for Future Research." Special Issue on Managing in the Age of Disruptions. Journal of Management Studies 55, no. 7 (November 2018): 1043–1078.
- Research Summary
Overview
My current research focuses on the role of AI in shaping organizational knowledge production, learning, and innovation processes. I run field experiments to study early-stage idea generation and evaluation in entrepreneurial context. View Details
- June 2013
- Teaching Note
Rock Health
By: Robert Higgins and Ian McKown Cornell
This is the teaching note associated with HBS Case #813035. The case should enable students to identify emerging challenges, evaluate Rock Health's funding model, debate the effectiveness of its incubation service and assess its long-term viability. View Details
- October 2012 (Revised October 2013)
- Case
Rock Health
By: Robert F. Higgins and Ian McKown Cornell
Rock Health was a San Francisco–based nonprofit organization offering accelerator services to spur innovation at the intersection of healthcare and technology. The company was the creation of Halle Tecco (HBS '11) and her HBS classmate Nate Gross (HBS '11), who met... View Details
Keywords: Innovation; Incubation; Healthcare Technology; Startups; Entrepreneurship; Innovation and Management; Health Care and Treatment; Business Startups; Health Industry; San Francisco; California; United States
Higgins, Robert F., and Ian McKown Cornell. "Rock Health." Harvard Business School Case 813-035, October 2012. (Revised October 2013.)
- October 2012 (Revised February 2014)
- Teaching Note
Logoplaste: Global Growing Challenges (TN)
By: Juan Alcacer
The case follows Logoplaste in its transformation from a small player in the plastic container industry in Portugal to a mid-sized global firm with operations in 11 countries. The case summarizes Logoplaste's history, with an emphasis on the milestones of its global... View Details
- September 2022
- Article
A Spanner in the Works: Category-Spanning Entrants and Audience Valuation of Incumbents
By: Rory M. McDonald and Ryan T. Allen
Previous work has examined how audiences evaluate category-spanning organizations, but little is known about how their entrance affects evaluations of other, proximate organizations. We posit that the emergence of category-spanning entrants signals the advent of an... View Details
Keywords: Emerging Industries; Industry Dynamics; Organization And Management Theory; Technology Strategy; Technology And Innovation Management; Entrepreneurship; Information Technology; Strategy; Management; Theory; Innovation and Management
McDonald, Rory M., and Ryan T. Allen. "A Spanner in the Works: Category-Spanning Entrants and Audience Valuation of Incumbents." Strategy Science 7, no. 6 (September 2022): 190–209.
- September 2024
- Case
Myeloma Investment Fund
By: Kyle Myers and Scott Sawaya
This case explores a critical decision facing the Myeloma Investment Fund (MIF) as it evaluates two investment opportunities aimed at accelerating a cure for multiple myeloma.
The MIF, a venture philanthropy fund, must choose between two distinct paths. One... View Details
The MIF, a venture philanthropy fund, must choose between two distinct paths. One... View Details
Keywords: Venture Philanthropy; Biomedical Research; Investing For Impact; Innovation ＆ Entrepreneurship; Venture Capital; Science-Based Business; Philanthropy and Charitable Giving; Decision Making; Health Care and Treatment; Biotechnology Industry; Pharmaceutical Industry
Myers, Kyle, and Scott Sawaya. "Myeloma Investment Fund." Harvard Business School Case 625-047, September 2024.
- 2023
- Working Paper
Scoring and Funding Breakthrough Ideas: Evidence from a Global Pharmaceutical Company
By: Joshua Krieger, Ramana Nanda, Ian Hunt, Aimee Reynolds and Peter Tarsa
We study resource allocation to early-stage ideas at an internal startup program of
one the largest pharmaceutical firms in the world. Our research design enables us to
elicit every evaluator’s scores across five different attributes, before seeing how they
would... View Details
Keywords: Project Selection; Pharmaceuticals; Financing Innovation; Resource Allocation; Innovation and Invention; Research and Development
Krieger, Joshua, Ramana Nanda, Ian Hunt, Aimee Reynolds, and Peter Tarsa. "Scoring and Funding Breakthrough Ideas: Evidence from a Global Pharmaceutical Company." Harvard Business School Working Paper, No. 23-014, August 2022. (Revised November 2023.)
- 2023
- Working Paper
Judging Foreign Startups
By: Nataliya Langburd Wright, Rembrand Koning and Tarun Khanna
Can accelerators pick the most promising startup ideas no matter their provenance? Using unique data from a global accelerator where judges are randomly assigned to evaluate startups headquartered across the globe, we show that judges are less likely to recommend... View Details
Keywords: Entrepreneurship And Strategy; Entrepreneurial Financing; Innovation; Bias; International; Strategy; Entrepreneurship; Global Strategy; Business Startups; Financing and Loans; Decision Making
Wright, Nataliya Langburd, Rembrand Koning, and Tarun Khanna. "Judging Foreign Startups." Harvard Business School Working Paper, No. 21-097, March 2021. (Revised January 2023. Accepted at the Strategic Management Journal.)
- September 2023
- Article
Judging Foreign Startups
By: Nataliya Langburd Wright, Rembrand Koning and Tarun Khanna
Can accelerators pick the most promising startup ideas no matter their provenance? Using unique data from a global accelerator where judges are randomly assigned to evaluate startups headquartered across the globe, we show that judges are less likely to recommend... View Details
Keywords: Entrepreneurship And Strategy; Global Strategy; Entrepreneurial Financing; Innovation; International; Entrepreneurship; Judgments; Business Startups; Geographic Location; Growth and Development Strategy
Wright, Nataliya Langburd, Rembrand Koning, and Tarun Khanna. "Judging Foreign Startups." Strategic Management Journal 44, no. 9 (September 2023): 2195–2225.
- September 2009 (Revised September 2010)
- Case
Genzyme Center (A)
By: Michael W. Toffel and Aldo Sesia
Genzyme Corporation is in the midst of planning its new corporate headquarters, which incorporates many innovative green building features. After learning that the building as planned would likely earn a LEED Silver rating, an intermediate score in the LEED green... View Details
Keywords: Green Building; LEED Rating System; Economic And Environmental Performance; Program Evaluation And Assessment; Tradeoffs Between Process- And Performance Standards; Buildings and Facilities; Business Headquarters; Governing Rules, Regulations, and Reforms; Standards; Corporate Social Responsibility and Impact; Performance Improvement; Environmental Sustainability; Pollutants; Green Technology Industry
Toffel, Michael W., and Aldo Sesia. "Genzyme Center (A)." Harvard Business School Case 610-008, September 2009. (Revised September 2010.)