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      Heterogeneous Treatment EffectsRemove Heterogeneous Treatment Effects →

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      • 2022
      • Working Paper

      Causal Inference During A Pandemic: Evidence on the Effectiveness of Nebulized Ibuprofen as an Unproven Treatment for COVID-19 in Argentina

      By: Sebastian Calonico, Rafael Di Tella and Juan Cruz Lopez Del Valle
      Many medical decisions during the pandemic were made without the support of causal evidence obtained in clinical trials. We study the case of nebulized ibuprofen (NaIHS), a drug that was extensively used on COVID-19 patients in Argentina amidst wild claims about its... View Details
      Keywords: COVID-19; Drug Treatment; Health Pandemics; Health Care and Treatment; Decision Making; Outcome or Result; Argentina
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      Calonico, Sebastian, Rafael Di Tella, and Juan Cruz Lopez Del Valle. "Causal Inference During A Pandemic: Evidence on the Effectiveness of Nebulized Ibuprofen as an Unproven Treatment for COVID-19 in Argentina." NBER Working Paper Series, No. 30084, May 2022.
      • Article

      How Much Should We Trust Staggered Difference-In-Differences Estimates?

      By: Andrew C. Baker, David F. Larcker and Charles C.Y. Wang
      We explain when and how staggered difference-in-differences regression estimators, commonly applied to assess the impact of policy changes, are biased. These biases are likely to be relevant for a large portion of research settings in finance, accounting, and law that... View Details
      Keywords: Difference In Differences; Staggered Difference-in-differences Designs; Generalized Difference-in-differences; Dynamic Treatment Effects; Mathematical Methods
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      Baker, Andrew C., David F. Larcker, and Charles C.Y. Wang. "How Much Should We Trust Staggered Difference-In-Differences Estimates?" Journal of Financial Economics 144, no. 2 (May 2022): 370–395. (Editor's Choice, May 2022; Jensen Prize, First Place, June 2023.)
      • 2022
      • Working Paper

      A Linear Panel Model with Heterogeneous Coefficients and Variation in Exposure

      By: Jesse M. Shapiro and Liyang Sun
      Linear panel models featuring unit and time fixed effects appear in many areas of empirical economics. An active literature studies the interpretation of the ordinary least squares estimator of the model, commonly called the two-way fixed effects (TWFE) estimator, in... View Details
      Keywords: Econometric Models; Mathematical Methods
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      Shapiro, Jesse M., and Liyang Sun. "A Linear Panel Model with Heterogeneous Coefficients and Variation in Exposure." NBER Working Paper Series, No. 29976, April 2022.
      • April–June 2022
      • Other Article

      Commentary on 'Causal Decision Making and Causal Effect Estimation Are Not the Same... and Why It Matters'

      By: Edward McFowland III
      There has been a substantial discussion in various methodological and applied literatures around causal inference; especially in the use of machine learning and statistical models to understand heterogeneity in treatment effects and to make optimal decision... View Details
      Keywords: Causal Inference; Treatment Effect Estimation; Treatment Assignment Policy; Human-in-the-loop; Decision Making; Fairness
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      McFowland III, Edward. "Commentary on 'Causal Decision Making and Causal Effect Estimation Are Not the Same... and Why It Matters'." INFORMS Journal on Data Science 1, no. 1 (April–June 2022): 21–22.
      • March 2022 (Revised March 2024)
      • Case

      DaVita Responds to COVID

      By: Susanna Gallani and David Lane
      Early in August 2021, DaVita CEO Javier Rodriguez was assessing the ongoing impact of the COVID-19 pandemic on his firm, which provided life-sustaining kidney dialysis to roughly 240,000 people. Effective infection control practices and information sharing had ensured... View Details
      Keywords: COVID-19 Pandemic; Change Management; Communication; Talent and Talent Management; Fairness; Values and Beliefs; Corporate Accountability; Health Care and Treatment; Health Pandemics; Human Resources; Employee Relationship Management; Retention; Wages; Working Conditions; Leadership Style; Crisis Management; Organizational Culture; Health Industry; United States
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      Gallani, Susanna, and David Lane. "DaVita Responds to COVID." Harvard Business School Case 122-007, March 2022. (Revised March 2024.)
      • March 2022
      • Article

      Estimating the Effectiveness of Permanent Price Reductions for Competing Products Using Multivariate Bayesian Structural Time Series Models

      By: Fiammetta Menchetti and Iavor Bojinov
      Researchers regularly use synthetic control methods for estimating causal effects when a sub-set of units receive a single persistent treatment, and the rest are unaffected by the change. In many applications, however, units not assigned to treatment are nevertheless... View Details
      Keywords: Causal Inference; Partial Interference; Synthetic Controls; Bayesian Structural Time Series; Mathematical Methods
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      Menchetti, Fiammetta, and Iavor Bojinov. "Estimating the Effectiveness of Permanent Price Reductions for Competing Products Using Multivariate Bayesian Structural Time Series Models." Annals of Applied Statistics 16, no. 1 (March 2022): 414–435.
      • March 2022
      • Article

      Where to Locate COVID-19 Mass Vaccination Facilities?

      By: Dimitris Bertsimas, Vassilis Digalakis Jr, Alexander Jacquillat, Michael Lingzhi Li and Alessandro Previero
      The outbreak of COVID-19 led to a record-breaking race to develop a vaccine. However, the limited vaccine capacity creates another massive challenge: how to distribute vaccines to mitigate the near-end impact of the pandemic? In the United States in particular, the new... View Details
      Keywords: Vaccines; COVID-19; Health Care and Treatment; Health Pandemics; Performance Effectiveness; Analytics and Data Science; Mathematical Methods
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      Bertsimas, Dimitris, Vassilis Digalakis Jr, Alexander Jacquillat, Michael Lingzhi Li, and Alessandro Previero. "Where to Locate COVID-19 Mass Vaccination Facilities?" Naval Research Logistics Quarterly 69, no. 2 (March 2022): 179–200.
      • 24 Feb 2022
      • Other Presentation

      The Fearless ICU

      By: Amy C. Edmondson
      The last 24 months have pushed ICU teams around the world to their limits. As we move forward, we need to heal and rebuild our critical care teams. Healthcare more than ever will require ICU teams to perform at the highest levels and to continuously innovate to deliver... View Details
      Keywords: Psychological Safety; Teams; Critical Care; Health Care and Treatment; Groups and Teams; Performance Effectiveness
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      "The Fearless ICU." Critical Matters (podcast), Sound Physicians, February 24, 2022.
      • February 2022
      • Case

      Cleveland Clinic Abu Dhabi

      By: Linda A. Hill and Emily Tedards
      In 2006, the Cleveland Clinic and Mubadala Investment Company partnered with a bold ambition to deliver world class healthcare in the United Arab Emirates. In 2015, after nearly a decade of planning and construction, Cleveland Clinic Abu Dhabi opened its doors. By... View Details
      Keywords: Organizational Behavior; Culture; Alignment; Organizational Effectiveness; Purpose; Impact; Leadership Development; Diversity; Collaboration; Co-creation; Learning Organizations; Empowerment; Teams; Team Dynamics; Teamwork; Team Effectiveness; Trust; Talent; Talent Development And Retention; Psychological Safety; Organizational Evolution; Coaching; Board; Analytics; Innovation; Data; Data Visualization; Digital Technology; Digital; Customer Experience; Experimentation; Change Management; Data-driven Decision-making; Debates; Ecosystem; Partnership; Telemedicine; Sustainability; Global Organizations; Local; Hospital; Healthcare; United Arab Emirates; Health Care and Treatment; Partners and Partnerships; Globalization; Quality; Organizational Culture; Mission and Purpose; Innovation and Management; Information Technology; Joint Ventures; Leadership; Performance Effectiveness; Abu Dhabi; United Arab Emirates
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      Hill, Linda A., and Emily Tedards. "Cleveland Clinic Abu Dhabi." Harvard Business School Case 422-058, February 2022.
      • February 2022
      • Case

      Cleveland Clinic Abu Dhabi (Abridged)

      By: Linda A. Hill and Emily Tedards
      In 2006, the Cleveland Clinic and Mubadala Investment Company partnered with a bold ambition to deliver world class healthcare in the United Arab Emirates. In 2015, after nearly a decade of planning and construction, Cleveland Clinic Abu Dhabi opened its doors. By... View Details
      Keywords: Organization Behavior; Culture; Alignment; Organizational Effectiveness; Purpose; Impact; Leadership Development; Diversity; Collaboration; Co-creation; Learning Organizations; Empowerment; Teams; Team Dynamics; Teamwork; Team Effectiveness; Trust; Talent; Talent Development And Retention; Psychological Safety; Organizational Evolution; Coaching; Board; Analytics; Innovation; Data; Data Visualization; Digital Technology; Digital; Customer Experience; Experimentation; Change Management; Data-driven Decision-making; Debates; Ecosystem; Partnership; Telemedicine; Sustainability; Global Organizations; Local; Hospital; Healthcare; United Arab Emirates; Health Care and Treatment; Partners and Partnerships; Globalization; Quality; Organizational Culture; Mission and Purpose; Innovation and Management; Information Technology; Joint Ventures; Leadership; Performance Effectiveness; Abu Dhabi; United Arab Emirates
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      Hill, Linda A., and Emily Tedards. "Cleveland Clinic Abu Dhabi (Abridged)." Harvard Business School Case 422-056, February 2022.
      • February 2022
      • Case

      Cleveland Clinic Abu Dhabi: Leading Through the Fog of the COVID-19 Pandemic

      By: Linda A. Hill and Emily Tedards
      As COVID-19 began to take lives, destroy healthcare systems, and shut down economies across the globe, Dr. Rakesh Suri, Chief Executive Officer of Cleveland Clinic Abu Dhabi, and his executive team adapted their leadership to instill the new levels of agility and... View Details
      Keywords: Organizational Behavior; Culture; Organizational Culture; Organizational Adaptation; Organizational Effectiveness; Alignment; Leadership; Innovation; Diversity; Collaboration; Co-creation; Learning Organizations; Empowerment; Teamwork; Ecosystem; Agility; Partnerships; Data-driven Decision-making; Operating Model; Risk Management; Virtual Work; Team Dynamics; Telemedicine; Metrics; Globalization; Pandemic; COVID-19; Hospital; Healthcare; United Arab Emirates; Middle East; Health Care and Treatment; Health Pandemics; Organizational Change and Adaptation; Crisis Management; Leading Change; Leadership Style; Digital Transformation; United Arab Emirates; Middle East
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      Hill, Linda A., and Emily Tedards. "Cleveland Clinic Abu Dhabi: Leading Through the Fog of the COVID-19 Pandemic." Harvard Business School Case 422-057, February 2022.
      • February 2022
      • Case

      Leading The UK Vaccine Task Force

      By: Amy C. Edmondson and Claudia Pienica
      This case describes the first six months of the UK Vaccine Taskforce, under the leadership of Kate Bingham. With a career spent in the private sector as a biotech investor, Bingham’s appointment within the government was considered unusual. The overarching brief given... View Details
      Keywords: COVID-19; Vaccine; Government; Health Pandemics; Health Care and Treatment; Science; Innovation and Invention; Groups and Teams; Leadership; Decision Making; Government and Politics; Health; Innovation and Management; Governance; Change; Government Administration; Health Industry; Financial Services Industry; Public Administration Industry; Europe; United Kingdom
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      Edmondson, Amy C., and Claudia Pienica. "Leading The UK Vaccine Task Force." Harvard Business School Case 622-079, February 2022.
      • 2022
      • Book

      The Role of Innovation and Entrepreneurship in Economic Growth

      By: Michael J. Andrews, Aaron Chatterji, Josh Lerner and Scott Stern
      We live in an era in which innovation and entrepreneurship seem ubiquitous, particularly in regions like Silicon Valley, Boston, and the Research Triangle Park. But many metrics of economic growth, such as productivity growth and business dynamism, have been at best... View Details
      Keywords: Productivity Growth; Production Technologies; Innovation and Invention; Entrepreneurship; Economic Growth; Competition; Organizational Design; Economic Slowdown and Stagnation
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      Andrews, Michael J., Aaron Chatterji, Josh Lerner, and Scott Stern, eds. The Role of Innovation and Entrepreneurship in Economic Growth. Chicago: University of Chicago Press, 2022.
      • 2022
      • Article

      Alleviating Time Poverty Among the Working Poor: A Pre-Registered Longitudinal Field Experiment

      By: A.V. Whillans and Colin West
      Poverty entails more than a scarcity of material resources—it also involves a shortage of time. To examine the causal benefits of reducing time poverty, we conducted a longitudinal feld experiment over six consecutive weeks in an urban slum in Kenya with a sample of... View Details
      Keywords: Time; Subjective Well Being; Administrative Costs; Friction; Poverty; Well-being; Money; Perception; Kenya
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      Whillans, A.V., and Colin West. "Alleviating Time Poverty Among the Working Poor: A Pre-Registered Longitudinal Field Experiment." Art. 719. Scientific Reports 12 (2022).
      • Article

      A Prescriptive Analytics Framework for Optimal Policy Deployment Using Heterogeneous Treatment Effects

      By: Edward McFowland III, Sandeep Gangarapu, Ravi Bapna and Tianshu Sun
      We define a prescriptive analytics framework that addresses the needs of a constrained decision-maker facing, ex ante, unknown costs and benefits of multiple policy levers. The framework is general in nature and can be deployed in any utility maximizing context, public... View Details
      Keywords: Prescriptive Analytics; Heterogeneous Treatment Effects; Optimization; Observed Rank Utility Condition (OUR); Between-treatment Heterogeneity; Machine Learning; Decision Making; Analysis; Mathematical Methods
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      McFowland III, Edward, Sandeep Gangarapu, Ravi Bapna, and Tianshu Sun. "A Prescriptive Analytics Framework for Optimal Policy Deployment Using Heterogeneous Treatment Effects." MIS Quarterly 45, no. 4 (December 2021): 1807–1832.
      • Article

      Social Technology: An Interdisciplinary Approach to Improving Care for Older Adults

      By: Arthur Kleinman, Hongtu Chen, Sue E. Levkoff, Ann Forsyth, David E. Bloom, Winnie Yip, Tarun Khanna, Conor J. Walsh, David Perry, Ellen W. Seely, Anne S. Kleinman, Yan Zhang, Yuan Wang, Jun Jing, Tianshu Pan, Ning An, Zhenggang Bai, Jiexiu Wang, Qing Liu and Fawwaz Habbal
      Population aging is a defining demographic reality of our era. It is associated with an increase in the societal burden of delivering care to older adults with chronic conditions or frailty. How to integrate global population aging and technology development to help... View Details
      Keywords: Health Care and Treatment; Age; Service Delivery; Information Technology; Collaborative Innovation and Invention
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      Kleinman, Arthur, Hongtu Chen, Sue E. Levkoff, Ann Forsyth, David E. Bloom, Winnie Yip, Tarun Khanna, Conor J. Walsh, David Perry, Ellen W. Seely, Anne S. Kleinman, Yan Zhang, Yuan Wang, Jun Jing, Tianshu Pan, Ning An, Zhenggang Bai, Jiexiu Wang, Qing Liu, and Fawwaz Habbal. "Social Technology: An Interdisciplinary Approach to Improving Care for Older Adults." Art. 729149. Frontiers in Public Health 9 (2021).
      • December 2021
      • Article

      Trade Policy Uncertainty and Stock Returns

      By: Marcelo Bianconi, Federico Esposito and Marco Sammon
      A recent literature has documented large real effects of trade policy uncertainty (TPU) on trade, employment, and investment, but there is little evidence that investors are compensated for bearing such risk. To quantify the risk premium associated with TPU, we exploit... View Details
      Keywords: Trade Policy; Uncertainty; Stock Returns; Risk Premium; Tariff Rates; Portfolio Analysis; Trade; Policy; Risk and Uncertainty; Stocks; Investment Return
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      Bianconi, Marcelo, Federico Esposito, and Marco Sammon. "Trade Policy Uncertainty and Stock Returns." Art. 102492. Journal of International Money and Finance 119 (December 2021).
      • November 2021
      • Article

      Panel Experiments and Dynamic Causal Effects: A Finite Population Perspective

      By: Iavor Bojinov, Ashesh Rambachan and Neil Shephard
      In panel experiments, we randomly assign units to different interventions, measuring their outcomes, and repeating the procedure in several periods. Using the potential outcomes framework, we define finite population dynamic causal effects that capture the relative... View Details
      Keywords: Panel Data; Dynamic Causal Effects; Potential Outcomes; Finite Population; Nonparametric; Mathematical Methods
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      Bojinov, Iavor, Ashesh Rambachan, and Neil Shephard. "Panel Experiments and Dynamic Causal Effects: A Finite Population Perspective." Quantitative Economics 12, no. 4 (November 2021): 1171–1196.
      • November 2021
      • Article

      Ratings, Reviews, and the Marketing of New Products

      By: Itay P. Fainmesser, Dominique Olié Lauga and Elie Ofek
      We study how user-generated content (UGC) about new products impacts a firm's advertising and pricing decisions and the effect on profits and market dynamics. We construct a two-period model where consumers value quality and are heterogeneous in their taste for the new... View Details
      Keywords: Online Reviews; Product Ratings; Social Networks; Word Of Mouth; Pricing; User-generated Content; Advertising; Product Marketing; Price; Consumer Behavior; Product Positioning; Social Media
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      Fainmesser, Itay P., Dominique Olié Lauga, and Elie Ofek. "Ratings, Reviews, and the Marketing of New Products." Management Science 67, no. 11 (November 2021): 7023–7045.
      • 2021
      • Article

      Don't Get It or Don't Spread It: Comparing Self-interested versus Prosocial Motivations for COVID-19 Prevention Behaviors

      By: Jillian J. Jordan, Erez Yoeli and David Rand
      COVID-19 prevention behaviors may be seen as self-interested or prosocial. Using American samples from MTurk and Prolific (total n = 6,850), we investigated which framing is more effective—and motivation is stronger—for fostering prevention behavior intentions. We... View Details
      Keywords: COVID-19; Prevention; Prosocial Motivation; Health Pandemics; Behavior; Motivation and Incentives
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      Jordan, Jillian J., Erez Yoeli, and David Rand. "Don't Get It or Don't Spread It: Comparing Self-interested versus Prosocial Motivations for COVID-19 Prevention Behaviors." Art. 20222. Scientific Reports 11 (2021).
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