Publications

20 May 2013
Op-Ed

Making America an Industrial Powerhouse Again

industries. Research funded by the Defense Advanced Research Projects Agency (DARPA) sowed the seeds for the internet and advanced computer graphics. And massive investments by the National Institutes of Health in biomedical research,... View Details

Keywords: by Gary Pisano; Manufacturing

May 2025 (Revised June 2025)
Supplement

Michael Ku and Global Clinical Supply at Pfizer Inc.: Bringing Hope to Patients (D)

By: Linda A. Hill and Lydia Begag

This fourth installment in the Pfizer Global Clinical Supply (GCS) transformation case series highlights how over a decade of cultural and digital evolution positioned GCS to meet unprecedented global challenges. In 2011, Michael Ku became the Vice President of GCS and... View Details

January–February 2023
Article

Forecasting COVID-19 and Analyzing the Effect of Government Interventions

By: Michael Lingzhi Li, Hamza Tazi Bouardi, Omar Skali Lami, Thomas Trikalinos, Nikolaos Trichakis and Dimitris Bertsimas

We developed DELPHI, a novel epidemiological model for predicting detected cases and deaths in the prevaccination era of the COVID-19 pandemic. The model allows for underdetection of infections and effects of government interventions. We have applied DELPHI across more... View Details

Keywords: COVID-19 Pandemic; Epidemics; Analytics and Data Science; Health Pandemics; AI and Machine Learning; Forecasting and Prediction

26 Apr 2016
First Look

April 26

do. Purchase this case: https://cb.hbsp.harvard.edu/cbmp/product/316042-PDF-ENG Harvard Business School Case 315-006 La Ribera Health Department La Ribera was a privately managed, publicly funded health... View Details

Keywords: Sean Silverthorne

28 Sep 2020
Working Paper Summaries

What Can Economics Say About Alzheimer's Disease?

Keywords: by Amitabh Chandra, Courtney Coile, and Corina Mommaerts; Health; Health

15 May 2018
First Look

New Research and Ideas, May 15, 2018

are also shown to be actors in periodic deglobalization waves. This was because their function was to reinforce the gaps in wealth and income rather than disrupt them. Business enterprises proved disappointing institutions for knowledge and View Details

Keywords: Dina Gerdeman

March 2022
Article

Where to Locate COVID-19 Mass Vaccination Facilities?

By: Dimitris Bertsimas, Vassilis Digalakis Jr, Alexander Jacquillat, Michael Lingzhi Li and Alessandro Previero

The outbreak of COVID-19 led to a record-breaking race to develop a vaccine. However, the limited vaccine capacity creates another massive challenge: how to distribute vaccines to mitigate the near-end impact of the pandemic? In the United States in particular, the new... View Details

Keywords: Vaccines; COVID-19; Health Care and Treatment; Health Pandemics; Performance Effectiveness; Analytics and Data Science; Mathematical Methods

February 2009
Teaching Note

Examining the Adoption of Drug-Eluting Stents (TN)

By: Elie Ofek and Peter Wickersham

Teaching Note for [509028]. View Details

Keywords: Technology Adoption; Product Launch; Risk and Uncertainty; Health Care and Treatment; Competitive Strategy

June 2021
Article

From Predictions to Prescriptions: A Data-driven Response to COVID-19

By: Dimitris Bertsimas, Léonard Boussioux, Ryan Cory-Wright, Arthur Delarue, Vassilis Digalakis Jr, Alexander Jacquillat, Driss Lahlou Kitane, Galit Lukin, Michael Lingzhi Li, Luca Mingardi, Omid Nohadani, Agni Orfanoudaki, Theodore Papalexopoulos, Ivan Paskov, Jean Pauphilet, Omar Skali Lami, Bartolomeo Stellato, Hamza Tazi Bouardi, Kimberly Villalobos Carballo, Holly Wiberg and Cynthia Zeng

The COVID-19 pandemic has created unprecedented challenges worldwide. Strained healthcare providers make difficult decisions on patient triage, treatment and care management on a daily basis. Policy makers have imposed social distancing measures to slow the disease, at... View Details

Keywords: COVID-19; Health Pandemics; AI and Machine Learning; Forecasting and Prediction; Analytics and Data Science

18 Sep 2007
First Look

First Look: September 18, 2007

spillovers but also the possible cost of outward spillovers. While less technologically advanced firms favor locations with high levels of industrial innovative activity, technologically advanced firms... View Details

Keywords: Martha Lagace

Article

Use of Connected Digital Products in Clinical Research Following the COVID-19 Pandemic: A Comprehensive Analysis of Clinical Trials

By: Caroline Marra, William J. Gordon and Ariel Dora Stern

Objectives: In an effort to mitigate COVID-19 related challenges for clinical research, the U.S. Food and Drug Administration (FDA) issued new guidance for the conduct of ‘virtual’ clinical trials in late March 2020. This study documents trends in the use of... View Details

Keywords: Connected Digital Products; Telehealth; Remote Monitoring; Health Testing and Trials; Research; Governing Rules, Regulations, and Reforms; Information Technology

Article

Managing the Use and Dissemination of Information about Biomarkers: The Importance of Incentive Structures.

By: Ariel Dora Stern

The use of biomarkers holds great promise for the development of new therapeutics and the acceleration of clinical research. However, biomarkers must be validated—a complex and costly endeavor. Importantly, biomarker validation is meaningfully shaped by economic and... View Details

Keywords: Biomarkers; Information Management; Health Care and Treatment; Motivation and Incentives

Find at Harvard

November 2009 (Revised August 2010)
Case

NovoCure Ltd.

By: William A. Sahlman and Sarah Flaherty

Venture capitalist William Doyle must raise $35 million for a portfolio company with a promising, novel cancer therapy, just as global capital markets are imploding in the fall of 2008. NovoCure, Ltd., has developed an electrical-field-based therapy, called Tumor... View Details

Keywords: Financial Crisis; Entrepreneurship; Venture Capital; Investment; Health Care and Treatment; Health Testing and Trials; Technological Innovation; Financial Services Industry

Educators

27 Apr 2021
Research & Ideas

New Research: Surviving Bankruptcy, Useful Economics, and Retirement

Technological Eclecticism Could Help Journal of Applied Corporate Finance Amar Bhidé “Keynes thought it would be ‘splendid’ if economists became more like dentists. Disciplinary economics has instead become more like physics in focusing... View Details

20 Jun 2017
First Look

First Look at New Research and Ideas, June 20

School Case 317-103 PharmAccess and the M-TIBA Platform: Leveraging Digital Technology in the Developing World PharmAccess is an Amsterdam-based NGO working to support the development of the private health... View Details

Keywords: Sean Silverthorne

July 2021
Article

Electronic Trace Data and Legal Outcomes: The Effect of Electronic Medical Records on Malpractice Claim Resolution Time

By: Sam Ransbotham, Eric Overby and Michael C. Jernigan

Information systems generate copious trace data about what individuals do and when they do it. Trace data may affect the resolution of lawsuits by, for example, changing the time needed for legal discovery. Trace data might speed resolution by clarifying what events... View Details

Keywords: Analytics and Data Science; Lawsuits and Litigation; Digital Transformation; Welfare; Health Industry

Find at Harvard

July 1985 (Revised January 1988)
Case

American Hospital Supply Corp.: The ASAP System (A)

American Hospital Supply, the largest firm in the U.S. hospital supply industry, has achieved success in part through the use of information systems. Changes in the hospital marketplace suggest a shift in strategy would be appropriate. What role should information... View Details

Keywords: Information Technology; Order Taking and Fulfillment; Health Industry; Health Industry; United States

Educators

2021
Working Paper

Who Closed the Schools?

By: Joshua D. Coval

This paper examines the differences in characteristics between U.S. public schools that opted for virtual instruction because of COVID-19, and schools that did not. Much of the variation can be explained by measures of the degree to which districts favored teachers... View Details

Keywords: Public Education; COVID-19; Virtual Learning; Education; Health Pandemics; Teaching; Internet and the Web; Policy; Outcome or Result; United States

March 17, 2021
Other Article

Beyond Pajamas: Sizing Up the Pandemic Shopper

By: Ayelet Israeli, Eva Ascarza and Laura Castrillo

A first look at how the COVID-19 pandemic impacted e-commerce apparel shopping in the US and the UK. Extensive analysis and interactive graphics utilizing millions of transactions.
While the pandemic is still playing out, our preliminary investigations... View Details