Publications
Publications
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(5,474)
- Faculty Publications (2,128)
- 2024
- Working Paper
Cephalosporins—Fighting Hospital Infections: Case Histories of Transformational Advances
By: Amar Bhidé, Srikant Datar and Katherine Stebbins
This case history describes the development of three generations of cephalosporins – antibiotics that have significantly reduced hospital infections. Specifically, we chronicle how: 1) Early (pre-cephalosporin) antibiotics were developed in the first half of the 20th... View Details
- 2025
- Working Paper
Prozac—Controversial Blockbuster: Case Histories of Transformational Advances
By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins
This case history describes the development of Prozac, a blockbuster drug that transformed
the treatment of depression – and became a cultural phenomenon in the United States. Specifically, we
chronicle the: 1) prior treatments for depression and the research that... View Details
- 2025
- Working Paper
Tamoxifen—Reducing Breast Cancer Risks: Case Histories of Transformational Advances
By: Amar Bhidé, Srikant Datar and Katherine Stebbins
We describe the development of tamoxifen, considered a “gold standard” treatment for
millions of breast cancer patients. Specifically, we describe breast cancer treatments before tamoxifen’s
development; the initial development of tamoxifen from 1960 to 1973;... View Details
- June 2020
- Case
Breakthroughs at Blueprint Medicines
By: Richard G. Hamermesh, Kathy Giusti and Susie L. Ma
Precision medicine company Blueprint Medicines was building a successful track record for bringing drug therapies to market 40% faster than average. The company had spent $40 million dollars and two years building a compound library that became its drug development... View Details
- June 2020 (Revised January 2024)
- Case
TraceTogether
By: Mitchell B. Weiss and Sarah Mehta
By April 7, 2020, over 1.4 million people worldwide had contracted the novel coronavirus (COVID-19). Governments raced to curb the spread of COVID-19 by scaling up testing, quarantining those infected, and tracing their possible contacts. It had taken Singapore’s... View Details
Keywords: COVID-19; Contact Tracing; Government Administration; Crisis Management; Health; Health Pandemics; Innovation and Invention; Innovation Leadership; Innovation Strategy; Technological Innovation; Social Issues; Information Technology; Mobile and Wireless Technology; Applications and Software; Technology Adoption; Health Industry; Public Administration Industry; Singapore
- 2020
- Other Teaching and Training Material
Leading the Charge: A Podcase about Product Management at Opower
By: Jeffrey Rayport and John J. Lafkas
The Opower podcase materials contain audio from professor Jeffrey Rayport's interview with Ben Foster, the former vice president of product management at Opower, and more recently the co-founder of Prodify. In the podcase, Ben discusses how product management works in... View Details
- June 2020 (Revised August 2020)
- Case
Majid Al Futtaim Retail Geographic Expansion: Brick or Click?
By: Juan Alcácer and Alpana Thapar
This case illustrates the challenges that retailers face when they aggressively pursue geographical growth by expanding both their physical store network and their online presence. It features Majid Al Futtaim (MAF) Retail, a franchisee of Carrefour hypermarkets in the... View Details
- June 2020
- Teaching Plan
Chief
By: Katherine B. Coffman, Jeffrey J. Bussgang, Kathleen L. McGinn, Julia Kelley, Amy Klopfenstein and Katherine Chen
Teaching Plan serves as a supplement to the case for “Chief: Role for Carolyn Childers” (920-019), “Chief: Role for Lindsay Kaplan” (920-020), and “Scaling at Chief” (920-021). View Details
Keywords: Negotiation; Negotiation Tactics; Negotiation Participants; Agreements and Arrangements; Business Ventures; Business Startups; Business Model; Business Growth and Maturation; Demographics; Gender; Ownership; Ownership Stake; Strategy; Business Strategy; Expansion; Competition; Finance; Capital; Venture Capital; Technology Industry; Technology Industry; North and Central America; United States; New York (city, NY); New York (state, US)
- June 2020
- Case
Extended Reality Extends into Enterprise?
By: David B. Yoffie, Kaushal Jain, Amy Villasenor, Vicky Xu and Annie Yang
While the growth of virtual reality started in gaming, the industry was increasingly focused on enterprise applications in 2020. This note explores the market opportunities and challenges for virtual reality and augmented reality in the enterprise, while diving into a... View Details
- June 2020
- Background Note
Customer Management Dynamics and Cohort Analysis
By: Elie Ofek, Barak Libai and Eitan Muller
The digital revolution has allowed companies to amass considerable amounts of data on their customers. Using this information to generate actionable insights is fast becoming a critical skill that firms must master if they wish to effectively compete and win in today’s... View Details
- June 2020
- Article
Frenemies in Platform Markets: Heterogeneous Profit Foci as Drivers of Compatibility Decisions
By: Ron Adner, Jianqing Chen and Feng Zhu
We study compatibility decisions of two competing platform owners that generate profits through both hardware sales and royalties from content sales. We consider a game-theoretic model in which two platforms offer different standalone utilities to users. We find that... View Details
- 2020
- Working Paper
Iterative Coordination and Innovation
By: Sourobh Ghosh and Andy Wu
Agile management practices from the software industry continue to transform the way organizations innovate across industries, yet they remain understudied in the organizations literature. We investigate the widespread Agile practice of iterative coordination: frequent... View Details
- May 2020
- Case
M-Lab: Enabling Innovation at Mitsubishi Corporation
By: Krishna Palepu and Allison M. Ciechanover
M-Lab’s founding goals were to infuse an innovation mindset into Mitsubishi Corporation; to catalyze new business opportunities; and to enable a dialogue between Japanese business and Silicon Valley. M-Lab housed representatives from each of Mitsubishi Corporation’s... View Details
- May 2020
- Case
Trust Merchant Bank
By: Ramon Casadesus-Masanell, Pippa Tubman Armerding, Dilyana Karadzhova Botha and Salim Dewji
Trust Merchant Bank (TMB), a leading bank in the Democratic Republic of Congo (DRC), needs to decide whether to enter the soon-to-be-liberalized insurance industry. Since its founding in 2004, TMB has played a pivotal role in reshaping the DRC banking landscape by... View Details
Keywords: Retail Banking; Financial Services; Financial Inclusion; Turnaround; Fintech; Banks and Banking; Financial Condition; Insurance; Corporate Strategy; Expansion; Business Model; Family Business; Entrepreneurship; Information Technology; Monopoly; Banking Industry; Insurance Industry; Africa; Congo, Democratic Republic of the
- May 2020
- Teaching Note
Bayer Crop Science
By: David E. Bell, Michael Norris and Mel Martin
Teaching Note for HBS Case No. 520-055. View Details
- May 2020 (Revised December 2022)
- Case
Soofa: Displaying the Right Path?
By: Jeffrey J. Bussgang, Amy Klopfenstein and Amram Migdal
In November 2019, Sandra Richter, co-founder and CEO of Soofa, a network of advertising-supported digital bulletin boards, must decide between two different fundraising and expansion plans for her company. One plan entails raising $15 million in a Series A round and... View Details
Keywords: Business Ventures; Business Model; Business Plan; Business Startups; Entrepreneurship; Decision Making; Decisions; Ethics; Geography; Geopolitical Units; Finance; Investment; Markets; Market Entry and Exit; Demand and Consumers; Network Effects; Media; Society; Urban Development; Sustainable Cities; Information Technology; Information Infrastructure; Digital Platforms; Strategy; Business Strategy; Expansion; Relationships; Partners and Partnerships; Capital; Venture Capital; Technology Industry; Technology Industry; Technology Industry; North and Central America; United States; Massachusetts; Cambridge
- May 2020
- Case
Numenta in 2020: The Future of AI
By: David B. Yoffie, Cameron Armstrong, Mei Tao and Marta Zwierz
In 2020, Numenta’s co-founder, Jeff Hawkins, completed his pathbreaking research on artificial intelligence. His co-founder and CEO, Donna Dubinsky, had to find a business model to monetize the technology. This case explores the challenges of building a business... View Details
- May 8, 2020
- Article
Which Covid-19 Data Can You Trust?
By: Satchit Balsari, Caroline Buckee and Tarun Khanna
The COVID-19 pandemic has produced a tidal wave of data, but how much of it is any good? And as a layperson, how can you sort the good from the bad? The authors suggest a few strategies for dividing the useful data from the misleading: Beware of data that’s too broad... View Details
- 2020
- Article
Public Sentiment and the Price of Corporate Sustainability
By: George Serafeim
Combining corporate sustainability performance scores based on environmental, social, and governance (ESG) data with big data measuring public sentiment about a company’s sustainability performance, I find that the valuation premium paid for companies with strong... View Details
Keywords: Sustainability; ESG; ESG (Environmental, Social, Governance) Performance; Investment Management; Investment Strategy; Big Data; Machine Learning; Environment; Environmental Sustainability; Corporate Governance; Performance; Asset Pricing; Investment; Management; Strategy; Human Capital; Public Opinion; Value; Analytics and Data Science
- May–June 2020
- Article
The Agenda for the Next Generation of Health Care Information Technology
By: Thomas W. Feeley, Zachary Landman and Michael E. Porter
As the diffusion of value-based health care efforts accelerates globally, the need for interoperable information technology systems that support value-based care is essential. Such systems are needed to facilitate dramatic improvements in patient outcomes and... View Details