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December 2019
Case

Forecasting ClimaCell

By: Joshua Lev Krieger, Christopher Stanton and James Barnett

A weather technology startup, ClimaCell considers the R&D trade-offs and financing implications of pursuing a proposed contract with a major automobile maker, rather than continuing its focus on building a scalable, all-purpose weather prediction engine. View Details

Keywords: Weather; Forecasting and Prediction; Technological Innovation; Research and Development; Finance; Cost vs Benefits; Decision Making; Strategy

01 Jul 2013
Research & Ideas

Crowdfunding a Poor Investment?

through the crowd to lesser-known microfinance borrowers in developing countries. Nanda puts most current crowdfunding platforms such as Kickstarter and Indiegogo in the equivalent of the donation or lending category. Kickstarter began as... View Details

Keywords: by Michael Blanding; Financial Services

March 2011 (Revised June 2013)
Case

Next Street, LLC

By: Richard S. Ruback and Royce Yudkoff

Next Street Financial, LLC was a modern merchant bank that provided high quality advisory services and capital to small- and mid-sized inner city businesses. Next Street was a for-profit business that aimed to increase the growth, profitability and success of its... View Details

Keywords: Development Economics; Entrepreneurship; Capital; Commercial Banking; Investment Funds; Urban Development; Financial Services Industry

July 2001 (Revised August 2005)
Case

Medicines Company, The

By: John T. Gourville

It is early 2001 and the Medicines Co. just received FDA approval to market Angiomax, a blood thinner to be used during angioplasties and heart procedures. It is intended to be a better alternative to Heparin, an 80-year-old drug that costs less then $10 per dose. The... View Details

Keywords: Business Model; Change Management; Decision Choices and Conditions; Cost Management; Price; Product Marketing; Product Launch; Product Development; Risk and Uncertainty; Health Industry; Pharmaceutical Industry

January 2025
Teaching Note

Vytal: Packaging-as-a-Service

By: George Serafeim, Michael W. Toffel and Stacy Straaberg

Teaching Note for HBS Case No. 124-007. The Germany-based startup Vytal operated the largest digital-native reusable packaging-as-a-service network globally, having raised nearly €15 million, established a large network of restaurant partners, and prevented the use of... View Details

December 2020 (Revised March 2022)
Teaching Note

Forecasting ClimaCell

By: Joshua Lev Krieger, Christopher Stanton and James Barnett

A weather technology startup, ClimaCell considers the R&D trade-offs and financing implications of pursuing a proposed contract with a major automobile maker, rather than continuing its focus on building a scalable, all-purpose weather prediction engine. View Details

Keywords: Weather; Forecasting and Prediction; Business Startups; Research and Development; Finance; Cost vs Benefits; Decision Making; Strategy; United States; Israel; Massachusetts; Colorado

July 2023
Article

Takahashi-Alexander Revisited: Modeling Private Equity Portfolio Outcomes Using Historical Simulations

By: Dawson Beutler, Alex Billias, Sam Holt, Josh Lerner and TzuHwan Seet

In 2001, Dean Takahashi and Seth Alexander of the Yale University Investments Office developed a deterministic model for estimating future cash flows and valuations for the Yale endowment’s private equity portfolio. Their model, which is simple and intuitive, is still... View Details

Keywords: Forecasting and Prediction; Investment Portfolio; Analytics and Data Science

January 2018 (Revised January 2019)
Case

ZappRx

By: Jeffrey J. Bussgang and Olivia Hull

In October 2015, ZappRx founder Zoe Barry is deciding between two business models for her health technology start-up. Her product, a software application that aims to expedite the prescription fulfillment process for patients with rare diseases, has attracted interest... View Details

Keywords: Speciality Drugs; Hub Services; Pivot; Speciality Prescriptions; Health Care and Treatment; Customization and Personalization; Internet and the Web; Business Model; Decision Choices and Conditions; Pharmaceutical Industry; Massachusetts

February 28, 2020
Article

How Tesla Sets Itself Apart

By: Lou Shipley

Tesla and its flamboyant, and sometimes erratic, innovator Elon Musk have turned the more than a century old industry upside down in a mere 16 years. Traditional automakers are ill prepared to compete in today’s software-centered world. Unlike nimble Tesla, they are... View Details

Keywords: Strategy; Information Technology; Transportation; Business Model; Technological Innovation; Disruption; Auto Industry

Find at Harvard

April 2011 (Revised May 2013)
Case

South Africa (A): Stuck in the Middle?

By: Richard H. K. Vietor and Diego Comin

Fifteen years after ending apartheid, formal unemployment in South Africa was still at 24%. While the country had grown at 4 to 5% annually during the 2000s, the financial crisis set it back by 1 million more unemployed. Moreover, it seemed as if the nation were stuck... View Details

Keywords: Financial Crisis; Inflation and Deflation; Policy; Employment; Wages; Competition; South Africa

March 2011 (Revised July 2011)
Case

Vestas' World of Wind

By: Thomas J. Steenburgh and Elena Corsi

The wind turbine manufacturer Vestas launched the industry's first highly localized and customized new product launch campaigns which used also new tools such as web 2.0 platforms. Used to operate in a market where demand exceeded supply, Vestas had lost contact with... View Details

Keywords: Customer Focus and Relationships; Marketing Channels; Internet and the Web; Product Launch; Demand and Consumers; Advertising Campaigns; Global Strategy; Customization and Personalization; Business and Stakeholder Relations; Finance; Product Marketing; Technology Adoption; Energy Industry

June 2004 (Revised June 2006)
Supplement

Vertex Pharmaceuticals: R&D Portfolio Management (A)

By: Gary P. Pisano, Lee Fleming and Eli Strick

Vertex Pharmaceuticals, Inc., a drug discovery company that recently decided to pursue a vertically integrated business model, chose to build up its clinical development and commercial capabilities and infrastructure. For the first time in its history, Vertex will... View Details

Keywords: Research and Development; Investment Portfolio; Pharmaceutical Industry

27 Mar 2007
First Look

First Look: March 27, 2007

A. El-Erian Periodical:IMF. Finance and Development 44, no. 1 (March 2007) Download the paper: http://www.imf.org/external/pubs/ft/fandd/2007/03/elerian.htm Venture Capital Investment Cycles: The Impact of... View Details

Keywords: Martha Lagace

January 2025 (Revised March 2025)
Case

Gavi and the 'Next' Pandemic

By: Tarun Khanna and Kerry Herman

In 2025, CEO Dr. Sania Nishtar and her team consider the lessons the Global Alliance for Vaccine and Immunizations (GAVI) learned from the pandemic. GAVI successfully brought COVID-19 vaccines to large swaths of the undeveloped and under-developed world by pooling... View Details

Keywords: Developing Countries and Economies; Health Care and Treatment; Health Pandemics; Crisis Management; Success; Innovation and Invention; Service Delivery; Organizational Change and Adaptation; Strategic Planning; Pharmaceutical Industry; Africa

March 2017
Case

From mHealth Hackathon to Reality: Diabetes Care

By: Kevin Schulman and Curry Cheek

This case explores the development of a business plan for a mobile health application for diabetes care. The case depicts a student team excited about the opportunity to improve the care of patients with diabetes by contracting an app. They go through a rigorous... View Details

Keywords: Innovation; Mobile Health Technologies; Health Care; Health Care Industry; Behavioral Economics; Applications and Software; Health Care and Treatment; Mobile and Wireless Technology; Innovation and Invention; Health Industry; Telecommunications Industry

February 1997 (Revised October 2002)
Case

The Exxel Group: September 1995

By: Josh Lerner, Alex Hoye and Gonzalo Pacanins

The Exxel Group, a private equity group based in Buenos Aires, is considering a buyout of Argencard, Mastercard's exclusive licensee in Argentina. To complete the deal, however, it will need to raise additional financing from U.S. investors. Both the valuation and the... View Details

Keywords: Leveraged Buyouts; Developing Countries and Economies; Private Equity; Financing and Loans; Investment; Negotiation Deal; Problems and Challenges; Valuation; United States; Buenos Aires

Brian L. Trelstad

Brian Trelstad is a Senior Lecturer at Harvard Business School in the General Management Unit and the Faculty Chair of the Advanced Leadership Initiative. He teaches elective courses on Social Entrepreneurship and Systems... View Details

Keywords: education industry; health care; service industry; emerging market private equity; private equity (other); venture capital industry

Allen S. Grossman

Allen Grossman was appointed a Harvard Business School Professor of Management Practice in July 2000. He joined the Business School faculty in July 1998, with a concurrent appointment as a Visiting Scholar at the Harvard Graduate School of Education (HGSE). He... View Details

Keywords: education industry; nonprofit industry

December 2005 (Revised September 2007)
Case

Canyon Johnson Urban Fund

By: Felix Oberholzer-Gee and Alexa Arena

Basketball star Earvin "Magic" Johnson and K. Robert Turner, managing partner of Canyon Johnson Urban Fund (CJUF), raised $271.7 million for investments in urban real estate. The fund considered two projects, both located in Hollywood, CA. The first was located on... View Details

Keywords: Investment; Projects; Business and Government Relations; Public Opinion; Urban Development; Real Estate Industry; Los Angeles

25 Apr 2014
Research & Ideas

To Pay or Not to Pay: Argentina and the International Debt Market

Editor's note. Argentina is in the midst of a continuing saga regarding its 2002 default on its sovereign debt, a case that the US Supreme Court will decide soon. HBS finance professor Laura Alfaro, who served from 2010 to 2012 as... View Details

Keywords: by Laura Alfaro

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