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  • All HBS Web  (1,340)
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    • Research  (898)
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  • All HBS Web  (1,340)
    • People  (4)
    • News  (228)
    • Research  (898)
    • Events  (4)
    • Multimedia  (7)
  • Faculty Publications  (497)
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  • August 2001
  • Case

Pharmaceutical Industry and the AIDS Crisis in Developing Countries, The

Explores the controversy over the pricing of AIDS drugs in poor countries. This issue has received wide publicity due to two events: 1) a court case in South Africa that seeks to force drug companies to license their patents and 2) the announcement by the Indian... View Details
Keywords: Competition; Developing Countries and Economies; Business and Government Relations; Pharmaceutical Industry; South Africa; India
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Kennedy, Robert E. "Pharmaceutical Industry and the AIDS Crisis in Developing Countries, The." Harvard Business School Case 702-010, August 2001.
  • 10 Jul 2006
  • Working Paper Summaries

Nationality and Multinationals in Historical Perspective

Keywords: by Geoffrey G. Jones
  • 12 Mar 2014
  • Research & Ideas

Entrepreneurship and Multinationals Drive Globalization

company Beiersdorf is the most dramatic. Beiersdorf faced the worst of all worlds in terms of political risk. It was a determined multinational investor before World War I, and then lost everything as the... View Details
Keywords: by Sean Silverthorne; Pharmaceutical; Pharmaceutical; Pharmaceutical; Pharmaceutical
  • January 2018
  • Supplement

BeiGene Supplemental PowerPoint

By: Willy C. Shih and Jimmy Zhang
BeiGene was a biopharmaceutical company founded on exploiting a temporal regulatory policy discontinuity. Because of regulatory challenges in China, most innovative new drugs launched there four to six years after their initial U.S. launches. This gave BeiGene a window... View Details
Keywords: Biotechnology; Pharmaceutical Company; Pharmaceuticals; China; Regulatory Environment; Business Strategy; Innovation Strategy; Situation or Environment; Pharmaceutical Industry; Pharmaceutical Industry; China
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Shih, Willy C., and Jimmy Zhang. "BeiGene Supplemental PowerPoint." Harvard Business School PowerPoint Supplement 618-043, January 2018.
  • 02 Sep 2002
  • Research & Ideas

Foreign Multinationals in the U.S.: A Rocky Road

What can companies today take away from the experience of myriad multinationals in the United States? A lot, says HBS professor Geoffrey G. Jones, a specialist in business history and international business.... View Details
Keywords: by Sarah Jane Johnston & Martha Lagace
  • October 2007 (Revised July 2013)
  • Case

Vertex Pharmaceuticals and the Cystic Fibrosis Foundation: Venture Philanthropy Funding for Biotech

By: Robert F. Higgins, Sophie LaMontagne and Brent Kazan
In 2001, Vertex Pharmaceuticals Incorporated acquired the San Diego-based biotech company, Aurora Biosciences. The combination of Vertex's and Aurora's technologies would improve the flow of novel drug candidates into development. However, several questions related to... View Details
Keywords: Philanthropy; Philanthropy Funding; Innovation; Funding Model; Venture Capital; Partners and Partnerships; Financing and Loans; Investment Funds; Acquisition; Philanthropy and Charitable Giving; Pharmaceutical Industry; Pharmaceutical Industry; San Diego
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Higgins, Robert F., Sophie LaMontagne, and Brent Kazan. "Vertex Pharmaceuticals and the Cystic Fibrosis Foundation: Venture Philanthropy Funding for Biotech." Harvard Business School Case 808-005, October 2007. (Revised July 2013.)
  • June 2002 (Revised November 2005)
  • Case

Life, Death, and Property Rights: The Pharmaceutical Industry Faces AIDS in Africa

By: Debora L. Spar
In the final years of the 20th century, the world was hit by a plague of epidemic proportions--AIDS, a life-threatening disease that remained stubbornly immune to any cure or vaccine. In the developed nations of the West, AIDS was slowly brought under control through a... View Details
Keywords: Patents; Health Pandemics; Corporate Social Responsibility and Impact; Pharmaceutical Industry; Africa
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Spar, Debora L., and Nick Bartlett. "Life, Death, and Property Rights: The Pharmaceutical Industry Faces AIDS in Africa." Harvard Business School Case 702-049, June 2002. (Revised November 2005.)
  • June 2017
  • Supplement

Transformation at Eli Lilly & Co. (C)

By: William R. Kerr and Alexis Brownell
Keywords: Eli Lilly; Pharmaceutical Companies; Restructuring; Organizational Change and Adaptation; Pharmaceutical Industry; Indiana; Indianapolis
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Kerr, William R., and Alexis Brownell. "Transformation at Eli Lilly & Co. (C)." Harvard Business School Supplement 817-137, June 2017.
  • July 2003 (Revised August 2003)
  • Case

Lamoiyan Corporation of the Philippines: Challenging Multinational Giants

A local Philippine toothpaste manufacturer, Lamoiyan Corp., faces the challenge of staying competitive against entrenched multinational giants. The company has managed to capture, at its peak, 20% of the Philippine toothpaste market and has become the number three... View Details
Keywords: Multinational Firms and Management; Competitive Strategy; Emerging Markets; Entrepreneurship; Consumer Products Industry; Philippines
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Coughlan, Peter J., and Jenny Illes. "Lamoiyan Corporation of the Philippines: Challenging Multinational Giants." Harvard Business School Case 704-405, July 2003. (Revised August 2003.)
  • 08 Dec 2003
  • Research & Ideas

Why Europe Lags in Pharmaceuticals and Biotech

Bastianelli, vice president of corporate development at ProSkelia Pharmaceuticals in France. Once companies are created, there is little incentive to improve, he said, and labor laws make it difficult to... View Details
Keywords: by Sean Silverthorne; Pharmaceutical; Pharmaceutical; Pharmaceutical; Pharmaceutical
  • June 1991
  • Case

Eli Lilly and Co.: European Pharmaceutical Operations

By: Michael Y. Yoshino
Keywords: Multinational Firms and Management; Pharmaceutical Industry; Europe
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Yoshino, Michael Y. "Eli Lilly and Co.: European Pharmaceutical Operations." Harvard Business School Case 391-234, June 1991.
  • January 1994
  • Article

Foreign Multinationals in British Manufacturing, 1850-1962

By: G. Jones and Frances Bostock
This article draws on a new database to describe the dimensions and characteristics of 685 foreign companies which established British manufacturing subsidiaries between 1850 and 1962. The numbers of foreign companies grew from the 1890s, expanded rapidly in the... View Details
Keywords: Multinational Firms and Management; Business Subsidiaries; Expansion; Chemicals; Metals and Minerals; Food; Mergers and Acquisitions; Market Entry and Exit; Research and Development; Trade; Investment; Production; United Kingdom; United States; Scotland; Wales
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Jones, G., and Frances Bostock. "Foreign Multinationals in British Manufacturing, 1850-1962." Business History 36, no. 1 (January 1994): 89–126.
  • August 2018 (Revised February 2019)
  • Case

Alvogen: Scaling Entrepreneurship

By: Daniel Isenberg, William R. Kerr and Alexis Brownell
Keywords: Pharmaceutical Companies; Scaling; Generic Drugs; Entrepreneurship; Leadership; Pharmaceutical Industry; Asia; Europe; United States; Iceland
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Isenberg, Daniel, William R. Kerr, and Alexis Brownell. "Alvogen: Scaling Entrepreneurship." Harvard Business School Case 819-038, August 2018. (Revised February 2019.)
  • June 2017
  • Supplement

Transformation at Eli Lilly & Co. (B)

By: William R. Kerr and Alexis Brownell
Keywords: Eli Lilly; Pharmaceutical Companies; Restructuring; Organizational Change and Adaptation; Pharmaceutical Industry; Indiana; Indianapolis
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Kerr, William R., and Alexis Brownell. "Transformation at Eli Lilly & Co. (B)." Harvard Business School Supplement 817-136, June 2017.
  • 2021
  • Chapter

Multinationals' Need for State Protection: The Creation of the Swiss Investment Risk Guarantee in the 1960s

By: Sabine Pitteloud
This chapter focuses on the role of Industrie-Holding, the Federation of Swiss Industrial Multinational Companies, in the introduction of an investment risk guarantee during the 1960s. The chapter therefore contributes to a) the growing body of literature on how... View Details
Keywords: Investments; Multinational Companies; Political Risk; Business & Government Relations; Investment; Multinational Firms and Management; Risk and Uncertainty; Business and Government Relations; Switzerland
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Pitteloud, Sabine. "Multinationals' Need for State Protection: The Creation of the Swiss Investment Risk Guarantee in the 1960s." In Security and Insecurity in Business History: Case Studies in the Perception and Negotiation of Threats, edited by Mark Jakob, Nina Kleinöder, and Christian Kleinschmidt, 111–134. Baden-Baden: Nomos Verlagsgesellschaft, 2021.
  • November 2016
  • Supplement

Alnylam Pharmaceuticals: Building Value from the IP Estate (B)

By: Vicki Sato, Willy Shih and Matt Higgins
The leader of a pioneering biotech company in the siRNA space weighs his options for scaling production capacity in advance of an anticipated commercial launch. Operational complexity and relative merits of in-house manufacturing versus a contractor model are... View Details
Keywords: Pharmaceutical Companies; Pharmaceutical Industry; Biotech; Biotechnology; Operational Complexity; Strategy; Manufacturing; Production; Strategic Planning; Intellectual Property; Biotechnology Industry; United States
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Sato, Vicki, Willy Shih, and Matt Higgins. "Alnylam Pharmaceuticals: Building Value from the IP Estate (B)." Harvard Business School Supplement 617-022, November 2016.
  • September 2020 (Revised January 2021)
  • Case

Catalys Pacific

By: Joshua Lev Krieger
In 2019, BT Slingsby founds Catalys Pacific, the first biotech “venture creation” fund in Tokyo. After convincing some of the biggest Japanese pharmaceutical firms to invest, BT hopes the fund can make a big splash and transform biotechnology innovation in Japan. After... View Details
Keywords: Pharmaceutical Companies; Biotech; Health Care; Entrepreneur; Innovation; International Business; Entrepreneurial Finance; Entrepreneurship; Finance; Innovation Strategy; Venture Capital; Strategy; Cross-Cultural and Cross-Border Issues; Pharmaceutical Industry; Pharmaceutical Industry; Tokyo
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Krieger, Joshua Lev. "Catalys Pacific." Harvard Business School Case 821-035, September 2020. (Revised January 2021.)
  • November 2024
  • Teaching Note

Martine Rothblatt and United Therapeutics: A Series of Implausible Dreams

By: Debora L. Spar and Julia M. Comeau
Teaching Note for HBS Case No. 323-039. In 1990, satellite expert and Sirius XM founder Martine Rothblatt was determined to save the life of her seven-year-old daughter, Jenesis, who was diagnosed with a terminal illness called Pulmonary Arterial Hypertension (PAH). At... View Details
Keywords: Pharmaceutical Companies; Technological And Scientific Innovation; Organ Donation; Health Care and Treatment; Health Disorders; Innovation and Invention; Growth and Development Strategy; Product Development; Pharmaceutical Industry; Pharmaceutical Industry; United States; District of Columbia
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Spar, Debora L., and Julia M. Comeau. "Martine Rothblatt and United Therapeutics: A Series of Implausible Dreams." Harvard Business School Teaching Note 325-058, November 2024.
  • November 2022 (Revised April 2024)
  • Case

Martine Rothblatt and United Therapeutics: A Series of Implausible Dreams

By: Debora L. Spar and Julia M. Comeau
In 1990, satellite expert and Sirius XM founder Martine Rothblatt was determined to save the life of her seven-year-old daughter, Jenesis, who was diagnosed with a terminal illness called Pulmonary Arterial Hypertension (PAH). At the time, there was little medication... View Details
Keywords: Pharmaceutical Companies; Technological And Scientific Innovation; Organ Donation; Health Care and Treatment; Health Disorders; Innovation and Invention; Pharmaceutical Industry; Pharmaceutical Industry; United States; District of Columbia
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Spar, Debora L., and Julia M. Comeau. "Martine Rothblatt and United Therapeutics: A Series of Implausible Dreams." Harvard Business School Case 323-039, November 2022. (Revised April 2024.)
  • August 2003 (Revised January 2013)
  • Case

Multinational Corporations in Apartheid-era South Africa: The Issue of Reparations

By: Geoffrey Jones and Cate Reavis
Considers the lawsuits filed on behalf of victims of apartheid against multinationals who operated in South Africa prior to 1994. Reviews the debates about divestment from and sanctions against South Africa from the 1950s. Includes case studies of companies that... View Details
Keywords: Ethics; Multinational Firms and Management; Government Legislation; Lawsuits and Litigation; Business and Government Relations; Prejudice and Bias; South Africa
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Jones, Geoffrey, and Cate Reavis. "Multinational Corporations in Apartheid-era South Africa: The Issue of Reparations." Harvard Business School Case 804-027, August 2003. (Revised January 2013.)
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