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      • Faculty Publications  (64)

      life sciencesRemove life sciences →

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      • May 2014 (Revised November 2014)
      • Supplement

      Houston We Have A Solution: NASA and Open Innovation (B)

      By: Michael Tushman, Hila Lifshitz-Assaf and Kerry Herman
      Jeff Davis, director of Space Life Sciences Directorate at NASA, has been working for several years to raise awareness amongst scientists and researchers in his organizations of the benefits of open innovation as a successful and efficient way to collaborate on... View Details
      Keywords: Technology; Aerospace Industry
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      Tushman, Michael, Hila Lifshitz-Assaf, and Kerry Herman. "Houston We Have A Solution: NASA and Open Innovation (B)." Harvard Business School Supplement 414-057, May 2014. (Revised November 2014.)
      • 2014
      • Working Paper

      The Organizational and Geographic Drivers of Absorptive Capacity: An Empirical Analysis of Pharmaceutical R&D Laboratories

      By: Francesca Lazzeri and Gary P. Pisano
      Scholars and practitioners alike now recognize that a firm's capacity to assimilate and use know-how from external sources—what Cohen and Levinthal (1990) called "absorptive capacity"—plays a central role in innovation performance. In recent years, a common strategy... View Details
      Keywords: Geographic Location; Industry Clusters; Knowledge Acquisition; Pharmaceutical Industry; San Francisco; San Diego; Massachusetts
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      Lazzeri, Francesca, and Gary P. Pisano. "The Organizational and Geographic Drivers of Absorptive Capacity: An Empirical Analysis of Pharmaceutical R&D Laboratories." Harvard Business School Working Paper, No. 14-098, April 2014.
      • February 2014
      • Case

      BGI: Data-driven Research

      By: Willy Shih and Sen Chai
      BGI has the largest installed gene-sequencing capacity in the world, and to Zhang Gengyun, general manager of the Life Sciences Division, this represented an opportunity to apply his training as a plant breeder and his early career work as a biochemist to improving... View Details
      Keywords: Genomics; Gene Sequencing; Life Sciences; Plant Breeding; Human Genome Program; Beijing Genomics Institute; BGI; Rice Genome; Technological Innovation; Innovation Strategy; Research; Research and Development; Science; Genetics; Science-Based Business; Strategy; Commercialization; Corporate Strategy; Information Technology; Applications and Software; Agriculture and Agribusiness Industry; Biotechnology Industry; Food and Beverage Industry; China; United States
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      Shih, Willy, and Sen Chai. "BGI: Data-driven Research." Harvard Business School Case 614-056, February 2014.
      • January 2014 (Revised December 2014)
      • Case

      GenapSys: Business Models for the Genome

      By: Richard G. Hamermesh, Joseph B. Fuller and Matthew Preble

      GenapSys, a California-based startup, was soon to release a new DNA sequencer that the company's founder, Hesaam Esfandyarpour, believed was truly revolutionary. The sequencer would be substantially less expensive—potentially costing just a few thousand dollars—and... View Details

      Keywords: DNA Sequencing; Life Sciences; Business Model; Innovation & Entrepreneurship; Health Care and Treatment; Genetics; Business Strategy; Biotechnology Industry; Pharmaceutical Industry; Technology Industry; Health Industry; Medical Devices and Supplies Industry; United States
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      Hamermesh, Richard G., Joseph B. Fuller, and Matthew Preble. "GenapSys: Business Models for the Genome." Harvard Business School Case 814-050, January 2014. (Revised December 2014.)
      • August 2013
      • Course Overview Note

      Building Life Science Businesses Fall 2013: Course Outline and Syllabus

      By: Richard G. Hamermesh
      This Course Outline and Syllabus gives an overview of the Fall 2013 class Building Life Science Businesses. View Details
      Keywords: Healthcare Ventures; Entrepreneurial Management; Entrepreneurship; Entrepreneurs; Health Care and Treatment; Health Testing and Trials; Medical Specialties; Health Industry; Biotechnology Industry; Medical Devices and Supplies Industry; Asia; North America; Europe
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      Hamermesh, Richard G. "Building Life Science Businesses Fall 2013: Course Outline and Syllabus." Harvard Business School Course Overview Note 814-019, August 2013.
      • January 2013 (Revised September 2013)
      • Case

      Royal DSM: Fighting Hidden Hunger

      By: Rebecca Henderson, Noah Fisher and Mary Shelman
      In 2007 Royal DSM, a leading life science and materials company, entered a partnership with the World Food Programme (WFP) to combat hidden hunger around the world by providing micronutrient solutions. The case investigates the unexpectedly large impact the partnership... View Details
      Keywords: Conflict of Interests; Human Needs; Partners and Partnerships; Global Range; Nutrition; Science-Based Business; Non-Governmental Organizations; Service Industry; Health Industry
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      Henderson, Rebecca, Noah Fisher, and Mary Shelman. "Royal DSM: Fighting Hidden Hunger." Harvard Business School Case 313-085, January 2013. (Revised September 2013.)
      • September 2012 (Revised September 2012)
      • Course Overview Note

      Building Life Science Businesses Fall 2012: Course Outline and Syllabus

      By: Richard G. Hamermesh and Richard G. Hamermesh
      This Course Outline and Syllabus gives an overview of the Fall 2012 class Building Life Science Businesses View Details
      Keywords: Healthcare Ventures; Entrepreneurial Management; Entrepreneurship; Entrepreneurs; Health Care and Treatment; Health Testing and Trials; Medical Specialties; Health Industry; Biotechnology Industry; Medical Devices and Supplies Industry; Asia; North America; Europe
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      Hamermesh, Richard G. "Building Life Science Businesses Fall 2012: Course Outline and Syllabus." Harvard Business School Course Overview Note 812-167, September 2012. (Revised from original June 2012 version.)
      • 2012
      • Chapter

      The Confederacy of Heterogeneous Software Organizations and Heterogeneous Developers: Field Experimental Evidence on Sorting and Worker Effort

      By: Kevin J. Boudreau and Karim R. Lakhani
      Software development occurs in a patchwork or "confederacy" of different types of institutions (universities, small start-ups, multinational enterprises, government agencies, etc.) utilizing varied work approaches. Here we speculate on one possible explanation for this... View Details
      Keywords: Innovation and Invention; Applications and Software; Product Development; Organizations; Employees; Behavior; Competition; Cooperation; Creativity; Information Technology Industry
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      Boudreau, Kevin J., and Karim R. Lakhani. "The Confederacy of Heterogeneous Software Organizations and Heterogeneous Developers: Field Experimental Evidence on Sorting and Worker Effort." In The Rate and Direction of Inventive Activity Revisited, edited by Josh Lerner and Scott Stern, 483–502. University of Chicago Press, 2012.
      • 2011
      • Book

      Getting to Giving: Fundraising the Entrepreneurial Way

      By: Howard H. Stevenson and Shirley M. Spence
      Getting to Giving is based on Stevenson's many years as a donor, fundraiser and entrepreneur. The book offers practical techniques and real life stories, and brings passion and humor to the art and science of asking for money. Topics included in the book... View Details
      Keywords: Fund Raising; Fundraising; Non-profit Management; Strategy; Nonprofit Organizations; Philanthropy and Charitable Giving
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      Stevenson, Howard H., and Shirley M. Spence. Getting to Giving: Fundraising the Entrepreneurial Way. Belmont, MA: Timberline LLC, 2011.
      • 2011
      • Book

      Accelerating Energy Innovation: Insights from Multiple Sectors

      By: Rebecca Henderson and Richard G. Newell
      Accelerating energy innovation could be an important part of an effective response to the threat of climate change. Written by a stellar group of experts in the field, this book complements existing research on the subject with an exploration of the role that public... View Details
      Keywords: Energy Sources; Innovation and Invention; Climate Change; Policy; Competition; Demand and Consumers; Finance; Energy Industry
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      Henderson, Rebecca, and Richard G. Newell, eds. Accelerating Energy Innovation: Insights from Multiple Sectors. National Bureau of Economic Research Conference Report. University of Chicago Press, 2011.
      • 2010
      • Chapter

      Lessons from Catastrophe Reinsurance

      By: Kenneth A. Froot
      Of the 20 most costly catastrophes since 1970, more than half have occurred since 2001. Is this an omen of what the 21st century will be? How might we behave in this new, uncertain, and more dangerous environment? Will our actions be rational or irrational? A select... View Details
      Keywords: Decision Making; Insurance; Risk and Uncertainty; Natural Disasters; Behavior
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      Froot, Kenneth A. "Lessons from Catastrophe Reinsurance." Chap. 20 in The Irrational Economist: Making Decisions in a Dangerous World, edited by Erwann Michel-Kerjan and Paul Slovic, 171–182. New York: PublicAffairs Books, 2010.
      • 2008
      • Working Paper

      Extending Producer Responsibility: An Evaluation Framework for Product Take-Back Policies

      By: Michael W. Toffel, Antoinette Stein and Katharine Lee
      Manufacturers are increasingly being required to adhere to product take-back regulations that require them to manage their products at the end of life. Such regulations seek to internalize products' entire life cycle costs into market prices, with the ultimate... View Details
      Keywords: Product; Cost; Corporate Social Responsibility and Impact; Environmental Sustainability
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      Toffel, Michael W., Antoinette Stein, and Katharine Lee. "Extending Producer Responsibility: An Evaluation Framework for Product Take-Back Policies." Harvard Business School Working Paper, No. 09-026, July 2008. (September 2008.)
      • May 2006 (Revised November 2006)
      • Case

      IKEA's Global Sourcing Challenge: Indian Rugs and Child Labor (A)

      By: Christopher A. Bartlett, Vincent Marie Dessain and Anders Sjoman
      Traces the history of IKEA's response to a TV report that its Indian carpet suppliers were using child labor. Describes IKEA's growth, including the importance of a sourcing strategy based on its close relationships with suppliers in developing countries. Details the... View Details
      Keywords: Developing Countries and Economies; Moral Sensibility; Policy; Employment; Contracts; Supply Chain Management; Organizational Culture; Natural Environment; Non-Governmental Organizations; Social Issues
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      Bartlett, Christopher A., Vincent Marie Dessain, and Anders Sjoman. "IKEA's Global Sourcing Challenge: Indian Rugs and Child Labor (A)." Harvard Business School Case 906-414, May 2006. (Revised November 2006.)
      • December 2005 (Revised October 2013)
      • Case

      Fred Khosravi and AccessClosure (A)

      By: Richard Hamermesh and Liz Kind
      Fred Khosravi is a serial medical device entrepreneur. In his latest venture, he must decide whether to sell now or continue to develop his current product and whether to market it, sell the company, or IPO. View Details
      Keywords: Negotiation; Medical Devices; Venture Capital; Life Sciences; Health Care Industry; Healthcare Technology; Healthcare Ventures; Business Startups; Decision Choices and Conditions; Entrepreneurship; Growth and Development Strategy; Medical Devices and Supplies Industry; United States
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      Hamermesh, Richard, and Liz Kind. "Fred Khosravi and AccessClosure (A)." Harvard Business School Case 806-044, December 2005. (Revised October 2013.)
      • Article

      Strategic Management of Product Recovery

      By: Michael W. Toffel
      Manufacturers of an expanding range of durable products are facing regulatory and market pressures to manage the products they manufactured upon their end of life (EOL). In part, this attention is motivated by a growing number of countries—especially across Europe and... View Details
      Keywords: Product; Environmental Sustainability; Cost Management; Government Legislation; Logistics; Risk and Uncertainty; Strategy; Europe; Asia; United States
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      Toffel, Michael W. "Strategic Management of Product Recovery." California Management Review 46, no. 2 (Winter 2004): 120–141.
      • June 2004
      • Case

      Aventis SA (A): Planning for a Merger

      By: Joshua D. Margolis and Carin-Isabel Knoop
      Eight executives at Hoechst and Rhone-Poulenc must make four crucial decisions on the eve of merging their companies to become Aventis--what would become the world's third largest pharmaceutical firm. In addition to formulating a vision and strategy, the two firms must... View Details
      Keywords: Problems and Challenges; Mergers and Acquisitions; Horizontal Integration; Organizational Design; Organizational Culture; Pharmaceutical Industry; United States
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      Margolis, Joshua D., and Carin-Isabel Knoop. "Aventis SA (A): Planning for a Merger." Harvard Business School Case 404-003, June 2004.
      • 14 Feb 2003
      • Other Presentation

      New Jersey Life Sciences Super-Cluster Initiative

      By: Michael E. Porter
      The study assessed the current competitive position of the Life Science super-cluster in New Jersey; identified its key strengths and weaknesses, challenges and opportunities; and developed an action agenda that is being used as a blueprint to improve the cluster's... View Details
      Keywords: Economics; Growth and Development; United States
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      Porter, Michael E. "New Jersey Life Sciences Super-Cluster Initiative." Prosperity New Jersey Annual Meeting, Princeton, NJ, February 14, 2003.
      • December 2001 (Revised July 2005)
      • Case

      E.I. du Pont de Nemours and Company: The Conoco Split-off (A)

      By: Stuart C. Gilson and Perry Fagan
      After taking 30% of its Conoco oil and gas subsidiary public in the largest domestic initial public offering (IPO) in U.S. history, management of E.I. du Pont de Nemours and Co. (DuPont) is considering divesting its remaining interest in Conoco. This goal is to be... View Details
      Keywords: Business Conglomerates; Business Subsidiaries; Restructuring; Non-Renewable Energy; Chemicals; Assets; Initial Public Offering; Business and Shareholder Relations; Diversification; Value; Chemical Industry; United States
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      Gilson, Stuart C., and Perry Fagan. "E.I. du Pont de Nemours and Company: The Conoco Split-off (A)." Harvard Business School Case 202-005, December 2001. (Revised July 2005.)
      • 2001
      • Chapter

      Transforming Life, Transforming Business: The Life Science Revolution

      By: Juan Enriquez and Ray A. Goldberg
      Keywords: Science-Based Business; Organizational Change and Adaptation; Human Needs; Welfare; Transformation
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      Enriquez, Juan, and Ray A. Goldberg. "Transforming Life, Transforming Business: The Life Science Revolution." In The Digital Enterprise: How To Reshape Your Business For A Connected World, edited by Nicholas G. Carr. Boston: Harvard Business School Press, 2001.
      • December 1998 (Revised September 1999)
      • Case

      Novartis: Betting on Life Sciences

      By: Ray A. Goldberg, Carin-Isabel Knoop and Srinivas Sunder
      The merger of Ciba-Geigy and Sandoz produced genomic-based synergies for health care, agribusiness, and nutritional supplements. How to build on the strength of the individual divisions and provide synergies that would continue Novartis' leadership role is the question... View Details
      Keywords: Mergers and Acquisitions; Business Divisions; Health Care and Treatment; Leadership; Product Positioning; Science-Based Business; Corporate Strategy; Pharmaceutical Industry
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      Goldberg, Ray A., Carin-Isabel Knoop, and Srinivas Sunder. "Novartis: Betting on Life Sciences." Harvard Business School Case 599-076, December 1998. (Revised September 1999.)
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