Publications
Publications
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- All HBS Web
(1,188)
- Faculty Publications (64)
- 2014
- Working Paper
The Organizational and Geographic Drivers of Absorptive Capacity: An Empirical Analysis of Pharmaceutical R&D Laboratories
By: Francesca Lazzeri and Gary P. Pisano
Scholars and practitioners alike now recognize that a firm's capacity to assimilate and use know-how from external sources—what Cohen and Levinthal (1990) called "absorptive capacity"—plays a central role in innovation performance. In recent years, a common strategy... View Details
- February 2014
- Case
BGI: Data-driven Research
By: Willy Shih and Sen Chai
BGI has the largest installed gene-sequencing capacity in the world, and to Zhang Gengyun, general manager of the Life Sciences Division, this represented an opportunity to apply his training as a plant breeder and his early career work as a biochemist to improving... View Details
Keywords: Genomics; Gene Sequencing; Life Sciences; Plant Breeding; Human Genome Program; Beijing Genomics Institute; BGI; Rice Genome; Technological Innovation; Innovation Strategy; Research; Research and Development; Science; Genetics; Science-Based Business; Strategy; Commercialization; Corporate Strategy; Information Technology; Applications and Software; Agriculture and Agribusiness Industry; Biotechnology Industry; Food and Beverage Industry; China; United States
- January 2014 (Revised December 2014)
- Case
GenapSys: Business Models for the Genome
By: Richard G. Hamermesh, Joseph B. Fuller and Matthew Preble
GenapSys, a California-based startup, was soon to release a new DNA sequencer that the company's founder, Hesaam Esfandyarpour, believed was truly revolutionary. The sequencer would be substantially less expensive—potentially costing just a few thousand dollars—and... View Details
- August 2013
- Course Overview Note
Building Life Science Businesses Fall 2013: Course Outline and Syllabus
This Course Outline and Syllabus gives an overview of the Fall 2013 class Building Life Science Businesses. View Details
- January 2013 (Revised September 2013)
- Case
Royal DSM: Fighting Hidden Hunger
By: Rebecca Henderson, Noah Fisher and Mary Shelman
In 2007 Royal DSM, a leading life science and materials company, entered a partnership with the World Food Programme (WFP) to combat hidden hunger around the world by providing micronutrient solutions. The case investigates the unexpectedly large impact the partnership... View Details
- September 2012 (Revised September 2012)
- Course Overview Note
Building Life Science Businesses Fall 2012: Course Outline and Syllabus
This Course Outline and Syllabus gives an overview of the Fall 2012 class Building Life Science Businesses View Details
- 2012
- Chapter
The Confederacy of Heterogeneous Software Organizations and Heterogeneous Developers: Field Experimental Evidence on Sorting and Worker Effort
By: Kevin J. Boudreau and Karim R. Lakhani
Software development occurs in a patchwork or "confederacy" of different types of institutions (universities, small start-ups, multinational enterprises, government agencies, etc.) utilizing varied work approaches. Here we speculate on one possible explanation for this... View Details
- 2011
- Book
Getting to Giving: Fundraising the Entrepreneurial Way
By: Howard H. Stevenson and Shirley M. Spence
Getting to Giving is based on Stevenson's many years as a donor, fundraiser and entrepreneur. The book offers practical techniques and real life stories, and brings passion and humor to the art and science of asking for money. Topics included in the book... View Details
- 2011
- Book
Accelerating Energy Innovation: Insights from Multiple Sectors
By: Rebecca Henderson and Richard G. Newell
Accelerating energy innovation could be an important part of an effective response to the threat of climate change. Written by a stellar group of experts in the field, this book complements existing research on the subject with an exploration of the role that public... View Details
- September 2010 (Revised November 2010)
- Case
Ze-gen: Commercializing Clean Tech
By: Lynda M. Applegate, Kaitlyn Lyons and Scott Prozeller
The Ze-gen case covers the first five years in the life of a clean-tech start-up. Ze-gen had developed an innovative technology that converted solid waste into synthesis gas (called syngas). This technology was in testing at the company's pilot plant, built next to the... View Details
- 2010
- Chapter
Lessons from Catastrophe Reinsurance
By: Kenneth A. Froot
Of the 20 most costly catastrophes since 1970, more than half have occurred since 2001. Is this an omen of what the 21st century will be? How might we behave in this new, uncertain, and more dangerous environment? Will our actions be rational or irrational? A select... View Details
- 2008
- Working Paper
Extending Producer Responsibility: An Evaluation Framework for Product Take-Back Policies
By: Michael W. Toffel, Antoinette Stein and Katharine Lee
Manufacturers are increasingly being required to adhere to product take-back regulations that require them to manage their products at the end of life. Such regulations seek to internalize products' entire life cycle costs into market prices, with the ultimate... View Details
- May 2006 (Revised November 2006)
- Case
IKEA's Global Sourcing Challenge: Indian Rugs and Child Labor (A)
By: Christopher A. Bartlett, Vincent Marie Dessain and Anders Sjoman
Traces the history of IKEA's response to a TV report that its Indian carpet suppliers were using child labor. Describes IKEA's growth, including the importance of a sourcing strategy based on its close relationships with suppliers in developing countries. Details the... View Details
- December 2005 (Revised October 2013)
- Case
Fred Khosravi and AccessClosure (A)
By: Richard Hamermesh and Liz Kind
Fred Khosravi is a serial medical device entrepreneur. In his latest venture, he must decide whether to sell now or continue to develop his current product and whether to market it, sell the company, or IPO. View Details
- Article
Strategic Management of Product Recovery
Manufacturers of an expanding range of durable products are facing regulatory and market pressures to manage the products they manufactured upon their end of life (EOL). In part, this attention is motivated by a growing number of countries—especially across Europe and... View Details
- June 2004
- Case
Aventis SA (A): Planning for a Merger
By: Joshua D. Margolis and Carin-Isabel Knoop
Eight executives at Hoechst and Rhone-Poulenc must make four crucial decisions on the eve of merging their companies to become Aventis--what would become the world's third largest pharmaceutical firm. In addition to formulating a vision and strategy, the two firms must... View Details
- 14 Feb 2003
- Other Presentation
New Jersey Life Sciences Super-Cluster Initiative
The study assessed the current competitive position of the Life Science super-cluster in New Jersey; identified its key strengths and weaknesses, challenges and opportunities; and developed an action agenda that is being used as a blueprint to improve the cluster's... View Details
- December 2001 (Revised July 2005)
- Case
E.I. du Pont de Nemours and Company: The Conoco Split-off (A)
By: Stuart C. Gilson and Perry Fagan
After taking 30% of its Conoco oil and gas subsidiary public in the largest domestic initial public offering (IPO) in U.S. history, management of E.I. du Pont de Nemours and Co. (DuPont) is considering divesting its remaining interest in Conoco. This goal is to be... View Details
- 2001
- Chapter
Transforming Life, Transforming Business: The Life Science Revolution
By: Juan Enriquez and Ray A. Goldberg
- December 1998 (Revised September 1999)
- Case
Novartis: Betting on Life Sciences
By: Ray A. Goldberg, Carin-Isabel Knoop and Srinivas Sunder
The merger of Ciba-Geigy and Sandoz produced genomic-based synergies for health care, agribusiness, and nutritional supplements. How to build on the strength of the individual divisions and provide synergies that would continue Novartis' leadership role is the question... View Details