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- Faculty Publications (90)
- Winter 2017
- Article
Why Big Data Isn't Enough
By: Sen Chai and Willy C. Shih
There is a growing belief that sophisticated algorithms can explore huge databases and find relationships independent of any preconceived hypotheses. But in businesses that involve scientific research and technological innovation, this approach is misguided and... View Details
Keywords: Big Data; Science-based; Science; Scientific Research; Data Analytics; Data Science; Data-driven Management; Data Scientists; Technological Innovation; Analytics and Data Science; Mathematical Methods; Theory
Chai, Sen, and Willy C. Shih. "Why Big Data Isn't Enough." Art. 58227. MIT Sloan Management Review 58, no. 2 (Winter 2017): 57–61.
- October 2016 (Revised September 2017)
- Case
The CRISPR-Cas9 Quarrel
By: Richard G. Hamermesh and Matthew G. Preble
In mid-2016, the Broad Institute and the University of California, Berkeley were in the middle of a contentious patent dispute over which entity controlled a breakthrough gene editing technology called CRISPR-Cas9. With CRISPR-Cas9, scientists might soon be able to... View Details
Keywords: CRISPR; Broad Institute; University Of California Berkeley; Intellectual Property; Patents; Law; Lawsuits and Litigation; Science; Genetics; Entrepreneurship; Biotechnology Industry; United States
Hamermesh, Richard G., and Matthew G. Preble. "The CRISPR-Cas9 Quarrel." Harvard Business School Case 817-020, October 2016. (Revised September 2017.)
- May 20, 2016
- Comment
World Health Organization Lacks Leadership to Combat Pandemics
By: John A. Quelch
When it comes to emergency preparedness for pandemics, the World Health Organization is falling short. It has not provided prompt and clear leadership to the world in combating either the Ebola or Zika viruses. Its leadership has been low energy, its representatives... View Details
Keywords: Global Health; World Health Organization; World Bank; Pandemics; Emergency Preparedness; Experience and Expertise; Decisions; Forecasting and Prediction; Communication Strategy; Nonverbal Communication; Framework; Governance; Government and Politics; Health; Management; Practice; Problems and Challenges; Projects; Risk and Uncertainty; Human Needs; Civil Society or Community; Social Issues; Welfare or Wellbeing; Biotechnology Industry; Health Industry; Journalism and News Industry; Medical Devices and Supplies Industry; Public Administration Industry; Tourism Industry; Transportation Industry; Travel Industry; Africa; Asia; Europe; Latin America; North and Central America; South America; West Indies
Quelch, John A. "World Health Organization Lacks Leadership to Combat Pandemics." Harvard Business School Working Knowledge (May 20, 2016).
- March 2016 (Revised March 2022)
- Teaching Note
Express Scripts: Promoting Prescription Drug Home Delivery (A) and (B)
By: John Beshears
The pharmacy benefit manager (PBM) sector processes prescription drug claims on behalf of companies that offer a prescription drug benefit to their employees. The case associated with this teaching note follows Bob Nease, chief scientist at Express Scripts, as he... View Details
Keywords: Pharmaceuticals; Prescription Drugs; Pharmacy Benefit Manager; PBM; Healthcare; Behavioral Economics; Choice Architecture; Active Choice; Service Delivery; Decision Choices and Conditions; Consumer Behavior; Distribution Channels; Health Care and Treatment; Service Industry; Pharmaceutical Industry
- February 2016
- Case
Express Scripts: Promoting Prescription Drug Home Delivery (A)
By: John Beshears, Patrick Rooney and Jenny Sanford
The pharmacy benefit manager (PBM) sector processes prescription drug claims on behalf of companies that offer a prescription drug benefit to their employees. This case follows Bob Nease, Chief Scientist at Express Scripts, as he considers methods to promote home... View Details
Keywords: Pharmaceuticals; Prescription Drugs; Pharmacy Benefit Manager; PBM; Healthcare; Behavioral Economics; Choice Architecture; Active Choice; Service Delivery; Decision Choices and Conditions; Health Care and Treatment; Order Taking and Fulfillment; Compensation and Benefits; Pharmaceutical Industry
Beshears, John, Patrick Rooney, and Jenny Sanford. "Express Scripts: Promoting Prescription Drug Home Delivery (A)." Harvard Business School Case 916-026, February 2016.
- February 2016 (Revised March 2022)
- Case
Express Scripts: Promoting Prescription Drug Home Delivery (B)
By: John Beshears, Patrick Rooney and Jenny Sanford
The pharmacy benefit manager (PBM) sector processes prescription drug claims on behalf of companies that offer a prescription drug benefit to their employees. This case follows Bob Nease, Chief Scientist at Express Scripts, as he considers methods to promote home... View Details
Keywords: Pharmaceuticals; Prescription Drugs; Pharmacy Benefit Manager; PBM; Healthcare; Behavioral Economics; Choice Architecture; Active Choice; Health Care and Treatment; Service Delivery; Decision Choices and Conditions; Order Taking and Fulfillment; Compensation and Benefits
Beshears, John, Patrick Rooney, and Jenny Sanford. "Express Scripts: Promoting Prescription Drug Home Delivery (B)." Harvard Business School Case 916-040, February 2016. (Revised March 2022.)
- December 2015 (Revised May 2016)
- Case
Jibo: A Social Robot for the Home
By: Jeffrey J. Bussgang and Christine Snively
In January 2015, Jibo Inc. had completed a raise of $25.3 million in Series A financing after a successful 2014 crowdfunding campaign for preorders of Jibo, the first social robot for the home. Over 4,800 Jibo units were preordered, generating $2.6 million in sales. On... View Details
Keywords: Business Development; Entrepreneurship; Applications and Software; Information Infrastructure; Business Startups; Technology Industry
Bussgang, Jeffrey J., and Christine Snively. "Jibo: A Social Robot for the Home." Harvard Business School Case 816-003, December 2015. (Revised May 2016.)
- July 2015
- Article
Skilled Immigration and the Employment Structures of U.S. Firms
By: Sari Pekkala Kerr, William R. Kerr and William F. Lincoln
We study the impact of skilled immigrants on the employment structures of U.S. firms using matched employer-employee data. Unlike most previous work, we use the firm as the lens of analysis to account for a greater level of heterogeneity and the fact that many skilled... View Details
Keywords: Firms; Scientists; Engineers; Inventors; H-1B; Age; Employment; Immigration; United States
Kerr, Sari Pekkala, William R. Kerr, and William F. Lincoln. "Skilled Immigration and the Employment Structures of U.S. Firms." Journal of Labor Economics 33, no. S1 (July 2015): S147–S186.
- February 2015 (Revised June 2016)
- Case
Solar Geoengineering
By: Joseph B. Lassiter III and Stephanie Puzio
On December 8th 2013, as Dr. David Keith was leaving the set of the Colbert Show, he couldn't help but replay the interview over and over in his mind. Did he actually get his point of view on solar geoengineering across or had he just added to the stereotype that he... View Details
Keywords: Geoengineering; Carbon; Carbon Emissions; Energy; Nuclear; Nuclear Energy; De-extinction; Climate Change; Engineering; Entrepreneurship; Innovation and Invention; Energy Sources; Green Technology Industry; Energy Industry
Lassiter, Joseph B., III, and Stephanie Puzio. "Solar Geoengineering." Harvard Business School Case 815-081, February 2015. (Revised June 2016.)
- 2015
- Chapter
Negotiations: Statistical Aspects
'Negotiation analysis' seeks to develop prescriptive theory and useful advice for negotiators and third parties. It generally emphasizes the parties' underlying interests, alternatives to negotiated agreement, approaches to productively manage the inherent tension... View Details
Sebenius, James K. "Negotiations: Statistical Aspects." In International Encyclopedia of the Social & Behavioral Sciences. 2nd ed. Edited by James D. Wright, 430–436. London: Elsevier, 2015.
- November 2014
- Case
Napalm: From Soldiers Field to Trang Bang
By: Tom Nicholas and Jonas Peter Akins
Napalm is one of the most destructive weapons ever to be invented. Yet, at its original inception it was nothing more than a technical challenge, and it was never intended to be used in indiscriminate antipersonnel warfare. The pathway of its development by a Harvard... View Details
Keywords: Moral Sensibility; War; Chemicals; Research and Development; Chemical Industry; Viet Nam; Cambridge; United States
Nicholas, Tom, and Jonas Peter Akins. "Napalm: From Soldiers Field to Trang Bang." Harvard Business School Case 815-060, November 2014.
- September 2014
- Case
Pfizer's Centers for Therapeutic Innovation (CTI)
By: Gary Pisano, James Weber and Kait Szydlowski
In 2010, Pfizer established four small research units in New York, Boston, San Francisco, and San Diego located close to several premier Academic Medical Centers (AMCs), or hospitals with adjoining medical schools. The goal of these units was to redesign collaboration... View Details
Keywords: Drug Development; Academic Collaboration; Research And Development; Innovation; Translational Research; Management; Operations; Problems and Challenges; Research; Science; Information Technology; Strategy; Biotechnology Industry; Pharmaceutical Industry; North and Central America; Europe; Asia
Pisano, Gary, James Weber, and Kait Szydlowski. "Pfizer's Centers for Therapeutic Innovation (CTI)." Harvard Business School Case 615-024, September 2014.
- 2014
- Article
Unequality: Who Gets What and Why It Matters
Who should get what, and what are the consequences? Economic inequality in the United States has been rising for decades, yet only recently have behavioral scientists explored two central questions surrounding the optimal level of inequality. First, what are the... View Details
Keywords: Inequality; Ethics; Productivity; Gambling; Equality and Inequality; Fairness; Income; Performance Productivity; United States
Norton, Michael I. "Unequality: Who Gets What and Why It Matters." Policy Insights from the Behavioral and Brain Sciences 1, no. 1 (2014): 151–155.
- May 2014 (Revised November 2014)
- Case
Houston We Have A Problem: NASA and Open Innovation (A)
By: Michael Tushman, Hila Lifshitz-Assaf and Kerry Herman
Jeff Davis, director of Space Life Sciences Directorate (SLSD) at NASA, has been working for several years to raise awareness amongst scientists and researchers in his organizations of the benefits of open innovation as a successful and efficient way to collaborate on... View Details
Tushman, Michael, Hila Lifshitz-Assaf, and Kerry Herman. "Houston We Have A Problem: NASA and Open Innovation (A)." Harvard Business School Case 414-044, May 2014. (Revised November 2014.)
- May 2014 (Revised November 2014)
- Supplement
Houston We Have A Solution: NASA and Open Innovation (B)
By: Michael Tushman, Hila Lifshitz-Assaf and Kerry Herman
Jeff Davis, director of Space Life Sciences Directorate at NASA, has been working for several years to raise awareness amongst scientists and researchers in his organizations of the benefits of open innovation as a successful and efficient way to collaborate on... View Details
Tushman, Michael, Hila Lifshitz-Assaf, and Kerry Herman. "Houston We Have A Solution: NASA and Open Innovation (B)." Harvard Business School Supplement 414-057, May 2014. (Revised November 2014.)
- February 2014
- Case
BGI: Data-driven Research
By: Willy Shih and Sen Chai
BGI has the largest installed gene-sequencing capacity in the world, and to Zhang Gengyun, general manager of the Life Sciences Division, this represented an opportunity to apply his training as a plant breeder and his early career work as a biochemist to improving... View Details
Keywords: Genomics; Gene Sequencing; Life Sciences; Plant Breeding; Human Genome Program; Beijing Genomics Institute; BGI; Rice Genome; Technological Innovation; Innovation Strategy; Research; Research and Development; Science; Genetics; Science-Based Business; Strategy; Commercialization; Corporate Strategy; Information Technology; Applications and Software; Agriculture and Agribusiness Industry; Biotechnology Industry; Food and Beverage Industry; China; United States
Shih, Willy, and Sen Chai. "BGI: Data-driven Research." Harvard Business School Case 614-056, February 2014.
- Forthcoming
- Chapter
Oil, Macroeconomic Volatility and Crime in the Determination of Beliefs in Venezuela
By: Rafael Di Tella, Javier Donna and Robert MacCulloch
Book Abstract: At the beginning of the twentieth century Venezuela had one of the poorest economies in Latin America, but by 1970 it had become the richest country in the region and one of the twenty richest countries in the world, ahead of countries such as Greece,... View Details
Keywords: Macroeconomics; Volatility; Crime and Corruption; Values and Beliefs; Non-Renewable Energy; Energy Industry; Venezuela
Di Tella, Rafael, Javier Donna, and Robert MacCulloch. "Oil, Macroeconomic Volatility and Crime in the Determination of Beliefs in Venezuela." Chap. 14 in Venezuela Before Chávez: Anatomy of an Economic Collapse, edited by Ricardo Hausmann and Francisco Rodriguez. Penn State University Press, 2014.
- 2013
- Book
Entrepreneurship and Multinationals: Global Business and the Making of the Modern World
By: Geoffrey Jones
This book examines the history of entrepreneurship and multinationals in the making of the modern world. In recent years economists, historians, and political scientists have written extensively on the history of globalization and patterns of global wealth and poverty,... View Details
Keywords: FDI; Economic History; Business History; Industrial Organization; Chinitz; Agglomeration; Clusters; Cities; Mines; Globalization; Entrepreneurship; Government and Politics; Banking Industry; Chemical Industry; Consumer Products Industry; Beauty and Cosmetics Industry; Electronics Industry; Africa; Asia; Europe; Latin America; Middle East; North and Central America; South America
Jones, Geoffrey. Entrepreneurship and Multinationals: Global Business and the Making of the Modern World. Northampton, MA: Edward Elgar Publishing, 2013.
- September 2013 (Revised November 2015)
- Case
Living Proof: Are We a Technology Company or a Beauty Company?
By: Willy Shih
Jon Flint came up with the idea of a science-based beauty company while talking with his hairdresser about the problems with typical hair and skin care products. Together with a small team that included Professor Robert Langer of MIT, he committed to assemble a team... View Details
Keywords: Hair Care; Personal Care; Science-based; R&D; Innovation and Invention; Innovation and Management; Innovation Leadership; Innovation Strategy; Technological Innovation; Marketing; Marketing Strategy; Product Marketing; Product Positioning; Science-Based Business; Business Strategy; Commercialization; Corporate Strategy; Technology Platform; Expansion; Beauty and Cosmetics Industry; United States; Boston; Cambridge
Shih, Willy. "Living Proof: Are We a Technology Company or a Beauty Company?" Harvard Business School Case 614-013, September 2013. (Revised November 2015.)
- April 2013 (Revised October 2013)
- Case
National Instruments
By: Lynda M. Applegate, Keri Pearlson and Natalie Kindred
This case explores the use of social media to support product design, customer support, marketing and HR activities at National Instruments (NI). Based in Austin, Texas, with over $1 billion in 2011 sales, NI designs, produces, and sells software and hardware platforms... View Details
Keywords: Organizational Structure; Applications and Software; Organizational Culture; Technological Innovation; Digital Platforms; Innovation and Management; Media; Management Systems; Social and Collaborative Networks; Information Technology Industry; Service Industry; Texas
Applegate, Lynda M., Keri Pearlson, and Natalie Kindred. "National Instruments." Harvard Business School Case 813-001, April 2013. (Revised October 2013.)