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January 2024
Teaching Note

Frank Cornelissen: The Great Sulfite Debate (A) & (B)

By: Tiona Zuzul

Teaching Note for HBS Case Nos. 724-391 and 724-398. In 2018, artisanal Italian vineyard Frank Cornelissen was one of the world’s leading natural wine vineyards. Its founder, Frank Cornelissen, faced weather related conditions that forced him to have to decide between... View Details

January 2024
Supplement

Frank Cornelissen: The Great Sulfite Debate (B)

By: Tiona Zuzul and Susan Pinckney

In 2018, artisanal Italian vineyard Frank Cornelissen was one of the world’s leading natural wine vineyards. Its founder, Frank Cornelissen, faced weather related conditions that forced him to have to decide between staying true to the tenets of the natural wine... View Details

January 2024 (Revised April 2024)
Case

Target Malaria: Editing Mosquitoes through Gene Drives

By: Shikhar Ghosh and Shweta Bagai

Target Malaria, a non-profit research consortium, is exploring the application of CRISPR-Cas9 gene editing technology to combat malaria in Sub-Saharan Africa. Its approach uses gene drives, a revolutionary tool, to suppress the population of malaria-carrying... View Details

Keywords: Health Disorders; Technological Innovation; Nonprofit Organizations; Business Strategy; Genetics; Ethics; Governing Rules, Regulations, and Reforms; United States; United Kingdom; Burkina Faso; Africa

January 2024
Background Note

Evaluating Innovations in the Organization of Primary Care: What Type of Innovation Is It and How Well Does It Align with the Six Factors?

By: Regina E. Herzlinger and James Wallace

How can we evaluate if innovative health care ventures can do good—benefit society—and do well—become financially viable? This question is the topic of the first module in the Innovating in Health Care course book.

This note and "Health Stop (A): What Type... View Details

Keywords: Business Model; Health Care and Treatment; Collaborative Innovation and Invention; Mission and Purpose; Alignment; Health Industry

January 2024 (Revised February 2024)
Case

OpenAI: Idealism Meets Capitalism

By: Shikhar Ghosh and Shweta Bagai

In November 2023, the board of OpenAI, one of the most successful companies in the history of technology, decided to fire Sam Altman, its charismatic and influential CEO. Their decision shocked the corporate world and had people wondering why OpenAI had designed a... View Details

Keywords: AI; AI and Machine Learning; Governing and Advisory Boards; Ethics; Strategy; Technological Innovation; Leadership

2023
Working Paper

Coordinated R&D Programs and the Creation of New Industries

By: Daniel P. Gross and Maria P. Roche

Complex systems technologies—including “deep tech”—are prone to numerous frictions that stymie commercial development. Yet technologies with these features underpin some of the most valuable industries of the past century. We examine how large, mission-oriented... View Details

Keywords: Research and Development; Policy; Business and Government Relations; Technological Innovation; Collaborative Innovation and Invention

October 2023 (Revised April 2024)
Case

ghSMART & Co: Building and Scaling a Time Smart Firm

By: Ashley Whillans and Sara Coronel Rodriguez

"For ghSMART, freedom is the first principle from which all good things flow”—Geoff Smart, Chairman and Founder, ghSMART. ghSMART was a leadership advisory firm that was grounded in the principle of freedom. Talented Consultants and Partners could work remotely from... View Details

Keywords: Time; Consulting Firms; Time Management; Talent and Talent Management; Employee Relationship Management; Innovation Strategy; Knowledge Sharing; Organizational Culture; Going Public; Partners and Partnerships; Expansion; Reputation

September 2023 (Revised June 2024)
Case

Kaspi.kz: Building Trust through Innovation

By: Sandra J. Sucher, Fares Khrais and Marilyn Morgan Westner

This case is written to help students explore how companies can maintain and develop trust while innovating, how to identify and respond effectively to warning signs that they may not be as trusted as they believe, and how being trusted can aid in expanding and growing... View Details

Keywords: Growth and Development Strategy; Organizational Culture; Trust; Technology Adoption; Innovation and Invention; Banking Industry

September 2023 (Revised September 2023)
Teaching Note

Roche: Innovation and Access to Healthcare

By: George Serafeim

Teaching Note for HBS Case No. 123-075. In May 2022, Roche Group, one of the largest healthcare companies in the world, hosted its first investor event focused exclusively on its efforts to impact access to healthcare. While Roche had recently set an ambitious goal to... View Details

Keywords: ESG; Access To Care; Healthcare; Healthcare Access; Innovation; Social Impact; Affordable; Health Care and Treatment; Innovation and Invention; Product Development; Resource Allocation; Corporate Social Responsibility and Impact; Health Industry

September 2023 (Revised September 2024)
Technical Note

Measuring and Managing Social Impact

By: Brian Trelstad, Gerald Chertavian and Susan Pinckney

A brief overview of how to measure social impact at nonprofits, social organizations, and impact investments. View Details

Keywords: Analysis; Change; Transformation; Decision Making; Cost vs Benefits; Decision Choices and Conditions; Decisions; Forecasting and Prediction; Public Sector; Entrepreneurship; Social Entrepreneurship; Fairness; Entrepreneurial Finance; Governance; Governing and Advisory Boards; Policy; Innovation and Management; Knowledge Acquisition; Knowledge Use and Leverage; Goals and Objectives; Growth and Development Strategy; Growth Management; Management Analysis, Tools, and Techniques; Management Practices and Processes; Resource Allocation; Measurement and Metrics; Standards; Strength and Weakness; Mission and Purpose; Success; Performance; Performance Evaluation; Philanthropy and Charitable Giving; Strategic Planning; Programs; Risk and Uncertainty; Social Enterprise; Non-Governmental Organizations; Social Issues; United States

September 2023 (Revised May 2025)
Teaching Note

On (A) and (B)

By: Ramon Casadesus-Masanell, Karolin Frankenberger, Sascha Mader, Jordan Mitchell and Karen Elterman

Teaching Note for "On," HBS Case No. 723-430. On is a premium performance running shoe company founded in Switzerland in 2010. The company rapidly gained traction through its unique CloudTec cushioning technology, its innovative midsole plate called the Speedboard, and... View Details

September 2023 (Revised September 2023)
Supplement

On Slides

By: Ramon Casadesus-Masanell, Karolin Frankenberger, Sascha Mader, Jordan Mitchell and Karen Elterman

Slides to support the teaching of the On case, 723-430. On is a premium performance running shoe company founded in Switzerland in 2010. The company rapidly gained traction through its unique CloudTec cushioning technology, its innovative midsole plate called the... View Details

July 2023 (Revised May 2024)
Case

India Stack: Digital Public Infrastructure for All

By: Tarun Khanna, Anjali Raina and Rachna Chawla

Amitabh Kant, India Sherpa in the year of India's G20 Presidency, and Nandan Nilekani iconic tech entrepreneur wondered how to share India's model of digital public infrastructure to build social and economic inclusion. 'India Stack', the umbrella term for India's DPI... View Details

Keywords: Digital Transformation; Information Technology; Technology Adoption; Developing Countries and Economies; Economic Growth; Information Technology Industry; Technology Industry; Telecommunications Industry; Asia; South Asia; India

June 2023 (Revised March 2024)
Case

Creating World-Class Board Governance at SECO

By: Krishna G. Palepu and Emer Moloney

In Spring 2023, SECO CEO Massimo Mauri had the ambition to grow the €200 million revenue technology company to a €1 billion company by 2030. Founded in Italy in the 1970s, the family-owned company had gone through a period of growth and internationalization,... View Details

June 2023
Case

Block: Creating an Ecosystem of Ecosystems

By: Lauren Cohen, Richard Ryffel, Grace Headinger and Ruoshi Qi

At Investor Day 2022, Block announced a new vision for its businesses: creating an ecosystem of ecosystems. Outside the norm for many public growth companies, Block had recently acquired a variety of new business streams in the creator economy and Bitcoin despite a... View Details

3 Jun 2023
Talk

Health Care Innovation Opportunities Created by COVID-19 and How to Make Them Happen

By: Regina E. Herzlinger

The crush of patients created by COVID enabled the creation of sites for care outside the traditional hospital, such as retail pharmacies, ambulatory surgery centers, urgent care centers, telemedicine, and wireless sensors. Public policy mirrored these changes by... View Details

Keywords: Policy; Health Pandemics; Health Care and Treatment; Innovation and Invention; Health Industry; Insurance Industry

June 2023
Case

Verve Therapeutics: Taking DNA Editing to Heart

By: Shikhar Ghosh and Shweta Bagai

Verve Therapeutics, a public biotech company based in Boston, created a novel approach to addressing cardiovascular disease (CVD) - a leading cause of deaths globally. The company's approach was a single shot treatment to permanently lower cholesterol, thus reducing... View Details

Keywords: AI; Genetic Engineering; Medicine; Health Care and Treatment; Genetics; Innovation Strategy; Business and Stakeholder Relations; Medical Specialties; Innovation and Invention; Entrepreneurship; Biotechnology Industry

April 5, 2023
Article

We Need an Operation Warp Speed for Long COVID

By: Esther K. Choo and Scott Duke Kominers

With millions of people affected and at least $1 trillion of economic value at stake, long COVID is our next national health emergency. View Details

Keywords: COVID; COVID-19; COVID-19 Pandemic; Scientific Research; Policy; Health Policy; Innovation; Science; Public Finance; Public Health; Health Disorders; Health Care and Treatment; Human Capital

April 2023 (Revised February 2024)
Case

AI Wars

By: Andy Wu, Matt Higgins, Miaomiao Zhang and Hang Jiang

In February 2024, the world was looking to Google to see what the search giant and long-time putative technical leader in artificial intelligence (AI) would do to compete in the massively hyped technology of generative AI. Over a year ago, OpenAI released ChatGPT, a... View Details

Keywords: AI; Artificial Intelligence; AI and Machine Learning; Technology Adoption; Competitive Strategy; Technological Innovation

March 2023 (Revised May 2025)
Case

On (A)

By: Ramon Casadesus-Masanell, Karolin Frankenberger and Sascha Mader

Founded in 2010, in just one decade, the Swiss company On had established itself as a main player in global sports footwear and apparel. Based on an unconventional strategy which one of the founders labeled as “obsessively distinct,” On grew its sales with a compound... View Details

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