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      • June 2023
      • Case

      Verve Therapeutics: Taking DNA Editing to Heart

      By: Shikhar Ghosh and Shweta Bagai
      Verve Therapeutics, a public biotech company based in Boston, created a novel approach to addressing cardiovascular disease (CVD) - a leading cause of deaths globally. The company's approach was a single shot treatment to permanently lower cholesterol, thus reducing... View Details
      Keywords: AI; Genetic Engineering; Medicine; Health Care and Treatment; Genetics; Innovation Strategy; Business and Stakeholder Relations; Medical Specialties; Innovation and Invention; Entrepreneurship; Biotechnology Industry
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      Ghosh, Shikhar, and Shweta Bagai. "Verve Therapeutics: Taking DNA Editing to Heart." Harvard Business School Case 823-113, June 2023.
      • June 2023
      • Article

      Why Is Dollar Debt Cheaper? Evidence from Peru

      By: Bryan Gutiérrez, Victoria Ivashina and Juliana Salomao
      In emerging markets, a significant share of corporate loans are denominated in dollars. Using novel data that enables us to see currency and the cost of credit, in addition to several other transaction-level characteristics, we re-examine the reasons behind dollar... View Details
      Keywords: Emerging Market Corporate Debt; Currency Mismatch; Liability Dollarization; Carry Trade; Currency; Emerging Markets; Borrowing and Debt; Interest Rates; Peru
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      Gutiérrez, Bryan, Victoria Ivashina, and Juliana Salomao. "Why Is Dollar Debt Cheaper? Evidence from Peru." Journal of Financial Economics 148, no. 3 (June 2023): 245–272.
      • 2023
      • Working Paper

      Setting Gendered Expectations? Recruiter Outreach Bias in Online Tech Training Programs

      By: Jacqueline N. Lane, Karim R. Lakhani and Roberto Fernandez
      Competence development in digital technologies, analytics, and artificial intelligence is increasingly important to all types of organizations and their workforce. Universities and corporations are investing heavily in developing training programs, at all tenure... View Details
      Keywords: STEM; Selection and Staffing; Gender; Prejudice and Bias; Training; Equality and Inequality; Competency and Skills
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      Lane, Jacqueline N., Karim R. Lakhani, and Roberto Fernandez. "Setting Gendered Expectations? Recruiter Outreach Bias in Online Tech Training Programs." Harvard Business School Working Paper, No. 23-066, April 2023. (Accepted by Organization Science.)
      • March 2023 (Revised March 2023)
      • Case

      Roche: Innovation and Access to Healthcare

      By: George Serafeim, Susanna Gallani and Benjamin Maletta
      In May 2022, Roche Group, one of the largest healthcare companies in the world, hosted its first investor event focused exclusively on its efforts to impact access to healthcare. While Roche had recently set an ambitious goal to double the number of patients that had... View Details
      Keywords: ESG (Environmental, Social, Governance) Performance; Sustainable Finance; Growth Strategy And Execution; Sustainability Targets; Impact Evaluation; Healthcare Access; Healthcare Innovation; Healthcare Systems; Healthcare Operations; Finance; Strategy; Health Testing and Trials; Health Care and Treatment; Growth Management; Measurement and Metrics; Innovation Strategy; Corporate Social Responsibility and Impact; Health Industry; Pharmaceutical Industry; Switzerland; North America; Europe; Asia; Latin America; Africa
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      Serafeim, George, Susanna Gallani, and Benjamin Maletta. "Roche: Innovation and Access to Healthcare." Harvard Business School Case 123-075, March 2023. (Revised March 2023.)
      • January–February 2023
      • Article

      Data-Driven COVID-19 Vaccine Development for Janssen

      By: Dimitris Bertsimas, Michael Lingzhi Li, Xinggang Liu, Jennings Xu and Najat Khan
      The COVID-19 pandemic has spurred extensive vaccine research worldwide. One crucial part of vaccine development is the phase III clinical trial that assesses the vaccine for safety and efficacy in the prevention of COVID-19. In this work, we enumerate the first... View Details
      Keywords: COVID-19; Health Testing and Trials; Forecasting and Prediction; AI and Machine Learning; Research; Pharmaceutical Industry
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      Bertsimas, Dimitris, Michael Lingzhi Li, Xinggang Liu, Jennings Xu, and Najat Khan. "Data-Driven COVID-19 Vaccine Development for Janssen." INFORMS Journal on Applied Analytics 53, no. 1 (January–February 2023): 70–84.
      • December 2022
      • Article

      Does Industry Employment of Active Regulators Weaken Oversight?

      By: Jonas Heese
      I study whether industry employment of active regulators weakens oversight. To examine this question, I exploit that the Financial Reporting Enforcement Panel (FREP), the German capital-market regulator responsible for enforcing public firms’ compliance with accounting... View Details
      Keywords: Conflict-of-interest Policies; Directorships; Enforcement Actions; Industry Employment; Self-regulatory Organizations; Governance Compliance; Governing and Advisory Boards; Policy; Conflict of Interests
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      Heese, Jonas. "Does Industry Employment of Active Regulators Weaken Oversight?" Management Science 68, no. 12 (December 2022): 9198–9218.
      • 2022
      • Working Paper

      The Issuance and Design of Sustainability-linked Loans

      By: Maria Loumioti and George Serafeim
      Sustainability-linked loans (i.e., syndicated loans for which pricing is linked to a sustainability performance indicator) have rapidly evolved into a significant private debt product. We find that sustainability-linked lending has been available mostly to borrowers... View Details
      Keywords: Sustainability; Sustainability Management; Credit Products; Loan Contracts; Loans; Corporate Finance; Credit Risk; Environment; ESG; ESG Ratings; Climate Change; Finance; Borrowing and Debt; Risk and Uncertainty; Credit
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      Loumioti, Maria, and George Serafeim. "The Issuance and Design of Sustainability-linked Loans." Harvard Business School Working Paper, No. 23-027, November 2022.
      • October 2022
      • Case

      Sustainable Finance at Itau BBA

      By: George Serafeim, Maria Loumioti and Benjamin Maletta
      As of August 2022, the Itau BBA had structured dozens of sustainability linked bonds, which made future interest payments a function of the borrower meeting a target for a sustainability metric, and had solidified its reputation as a pioneer of sustainable finance in... View Details
      Keywords: Sustainable Finance; Corporate Social Responsibility; Environmental Sustainability; Growth Strategy; Debt Contracting; Performance Metrics; Risk Assessment; ESG (Environmental, Social, Governance) Performance; Financial Instruments; Risk Management; Debt Securities; Measurement and Metrics; Banking Industry; Pulp and Paper Industry; Latin America
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      Serafeim, George, Maria Loumioti, and Benjamin Maletta. "Sustainable Finance at Itau BBA." Harvard Business School Case 123-036, October 2022.
      • October 2022 (Revised January 2025)
      • Case

      Founders First Capital Partners: An Approach to Capital Access Equity

      By: Brian Trelstad, Mel Martin and Amy Klopfenstein
      In June 2021, Kim T. Folsom, the founder and CEO of revenue-based financing firm Founders First Capital Partners (FFCP), must decide whether to issue another loan to OnShore Technology Group, an up-and-coming software validation company. FFCP provided revenue-based... View Details
      Keywords: Finance; Financial Instruments; Financing and Loans; Interest Rates; Investment Return; Revenue; Capital; Financial Services Industry; North and Central America; United States
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      Trelstad, Brian, Mel Martin, and Amy Klopfenstein. "Founders First Capital Partners: An Approach to Capital Access Equity." Harvard Business School Case 323-013, October 2022. (Revised January 2025.)
      • September 2022 (Revised January 2025)
      • Case

      The Pokémon Company: Evolving into an Everlasting Brand

      By: Tomomichi Amano and Masaki Nomura
      Super Bowl 50, the fiftieth annual championship game of the American National Football League played in February 2016, featured 52 commercials, and brands spent more than six million dollars each for a 30-second commercial slot. Surprisingly, the commercial that... View Details
      Keywords: Advertising; Brands and Branding; Marketing Strategy; Consumer Behavior; Growth and Development Strategy; Video Game Industry; Japan
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      Amano, Tomomichi, and Masaki Nomura. "The Pokémon Company: Evolving into an Everlasting Brand." Harvard Business School Case 523-022, September 2022. (Revised January 2025.)
      • July 2022
      • Article

      Countercyclical Prudential Buffers and Bank Risk-taking

      By: Manuel Illueca, Lars Norden, Joseph Pacelli and Gregory F. Udell
      We investigate the effects of countercyclical prudential buffers on bank risk-taking. We exploit the introduction of dynamic loan loss provisioning in Spain, mandating that banks use historical average loss rates in their estimation of loan loss provisions. We find... View Details
      Keywords: Banks; Bank Regulation; Macroprudential Policies; Bank Lending; Loan Loss Provisioning; Risk Taking; Banks and Banking; Financing and Loans; Governing Rules, Regulations, and Reforms; Risk and Uncertainty
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      Illueca, Manuel, Lars Norden, Joseph Pacelli, and Gregory F. Udell. "Countercyclical Prudential Buffers and Bank Risk-taking." Art. 100961. Journal of Financial Intermediation 51 (July 2022).
      • May 2022
      • Teaching Note

      Climate Action in Miami

      By: Rosabeth Moss Kanter and Catarina Martinez
      Teaching Note for HBS Case No. 322-101. The Miami metropolitan area is a global epicenter of climate risk from heat and sea level rise, but leaders have only recently mobilized for action to respond to this systemic challenge. Resilient 305 began a collaboration across... View Details
      Keywords: Climate Change; Climate Impact; Change; Leadership; Cross-sector Collaboration; Coalition; Ecosystem; Greenhouse Gas Emissions; Cities; Environmental Sustainability; Infrastructure; Green Technology; Environmental Management; Miami
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      Kanter, Rosabeth Moss, and Catarina Martinez. "Climate Action in Miami." Harvard Business School Teaching Note 322-128, May 2022.
      • May 2022
      • Case

      Rawbank's Illico Cash: Can 'Fast Money' Overcome Cash Dependency in the DRC?

      By: Lauren Cohen and Grace Headinger
      Thomas de Dreux-Brézé, the Head of Strategy and Project Management at Rawbank Congo in the Democratic Republic of the Congo (DRC), was perplexed as he reviewed annual adoption rates for the bank’s launch of Illico Cash 2.0. As the bank’s mobile money app, Illico Cash... View Details
      Keywords: Fintech; Inflation; Deflation; Rural; Urban; Emerging Market; Mobile Technology; Finance; Money; Inflation and Deflation; Business Growth and Maturation; Decision Choices and Conditions; Demographics; Developing Countries and Economies; Corporate Entrepreneurship; Behavioral Finance; Currency; Banks and Banking; Commercial Banking; Financial Strategy; Rural Scope; Urban Scope; Innovation Strategy; Emerging Markets; Network Effects; Consumer Behavior; Mobile and Wireless Technology; Technology Adoption; Banking Industry; Financial Services Industry; Technology Industry; Congo, Democratic Republic of the
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      Cohen, Lauren, and Grace Headinger. "Rawbank's Illico Cash: Can 'Fast Money' Overcome Cash Dependency in the DRC?" Harvard Business School Case 222-084, May 2022.
      • May 2022
      • Case

      Timnit Gebru: 'SILENCED No More' on AI Bias and The Harms of Large Language Models

      By: Tsedal Neeley and Stefani Ruper
      Dr. Timnit Gebru—a leading artificial intelligence (AI) computer scientist and co-lead of Google’s Ethical AI team—was messaging with one of her colleagues when she saw the words: “Did you resign?? Megan sent an email saying that she accepted your resignation.” Heart... View Details
      Keywords: Ethics; Employment; Corporate Social Responsibility and Impact; Technological Innovation
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      Neeley, Tsedal, and Stefani Ruper. "Timnit Gebru: 'SILENCED No More' on AI Bias and The Harms of Large Language Models." Harvard Business School Case 422-085, May 2022.
      • 2022
      • Working Paper

      Distributional Consequences of Monetary Policy Across Races: Evidence from the U.S. Credit Register

      By: Laura Alfaro, Ester Faia and Camelia Minoiu
      We examine the consequences of monetary policy on racial disparities, focusing on the role of bank lending to firms through collateral and selection channels. Leveraging comprehensive loan-level data from the U.S. credit register (Y-14Q) of the Federal Reserve, we show... View Details
      Keywords: Monetary Policy Transmission; Inequity; Credit Registry; Wealth; Collateral Channel; Selection; Racial Disparity; Racial Inequality; Equality and Inequality; Banks and Banking; Credit; Governing Rules, Regulations, and Reforms; Banking Industry; United States
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      Alfaro, Laura, Ester Faia, and Camelia Minoiu. "Distributional Consequences of Monetary Policy Across Races: Evidence from the U.S. Credit Register." Harvard Business School Working Paper, No. 22-068, April 2022.
      • 2023
      • Working Paper

      Uniform Rate Setting and the Deposit Channel

      By: Juliane Begenau and Erik Stafford
      U.S. banks predominantly use uniform deposit rate setting policies, particularly the largest banks. Uniform rate setting ignores local market concentration, and is therefore inconsistent with the identification strategy used to provide cross-sectional evidence of the... View Details
      Keywords: Banks and Banking; Financial Markets; Interest Rates; Banking Industry
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      Begenau, Juliane, and Erik Stafford. "Uniform Rate Setting and the Deposit Channel." Working Paper, December 2023.
      • April 2022 (Revised August 2022)
      • Case

      Conflicts of Interest at Uptown Bank

      By: Jonas Heese
      In 2013, two employees debated whether to blow the whistle on their employer, Bell Bank, after completing an internal review that revealed undisclosed conflicts of interest. Bell Bank’s Asset Management business disproportionately invested clients’ money in Bell Bank’s... View Details
      Keywords: Whistleblower; Whistleblowing; Mutual Funds; Conflicts Of Interest; Decision Making; Decisions; Judgments; Ethics; Moral Sensibility; Values and Beliefs; Finance; Financial Institutions; Banks and Banking; Financial Management; Investment; Investment Funds; Governance; Corporate Accountability; Corporate Disclosure; Corporate Governance; Governance Compliance; Governance Controls; Policy; Law; Legal Liability; Social Psychology; Motivation and Incentives; Perception; Perspective; Trust; Financial Services Industry; North and Central America; United States
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      Heese, Jonas. "Conflicts of Interest at Uptown Bank." Harvard Business School Case 122-022, April 2022. (Revised August 2022.)
      • March 31, 2022
      • Article

      Two Approaches to Capping Health Care Prices

      By: Michael E. Chernew, Maximilian J. Pany and Leemore S. Dafny
      High health care prices for the privately-insured contribute to high premiums, which put downward pressure on wages, and induce employers to reduce benefit generosity and charge employees more for coverage. As the average annual premium for family coverage currently... View Details
      Keywords: Price Caps; Health Care and Treatment; Price
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      Chernew, Michael E., Maximilian J. Pany, and Leemore S. Dafny. "Two Approaches to Capping Health Care Prices." Health Affairs Forefront (March 31, 2022).
      • March 2022 (Revised July 2022)
      • Case

      Climate Action in Miami

      By: Rosabeth Moss Kanter
      The Miami metropolitan area is a global epicenter of climate risk from heat and sea level rise, but leaders have only recently mobilized for action to respond to this systemic challenge. Resilient 305 began a collaboration across officials in the cities of Miami and... View Details
      Keywords: Climate Change; Climate Impact; Change; Leadership; Cross-sector Collaboration; Coalition; Ecosystem; Greenhouse Gas Emissions; Green Business; Adaptation; Environmental Sustainability; Infrastructure; Green Technology; Environmental Management; Miami
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      Kanter, Rosabeth Moss. "Climate Action in Miami." Harvard Business School Case 322-101, March 2022. (Revised July 2022.)
      • March 2022
      • Article

      Contractual Restrictions and Debt Traps

      By: Ernest Liu and Benjamin N. Roth
      Microcredit and other forms of small-scale finance have failed to catalyze entrepreneurship in developing countries. In these credit markets, borrowers and lenders often bargain over not only the interest rate but also implicit restrictions on types of investment. We... View Details
      Keywords: Microfinance; Entrepreneurship; Developing Countries and Economies; Financing and Loans
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      Liu, Ernest, and Benjamin N. Roth. "Contractual Restrictions and Debt Traps." Review of Financial Studies 35, no. 3 (March 2022): 1141–1182.
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