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  • All HBS Web  (1,056)
    • People  (3)
    • News  (261)
    • Research  (629)
    • Events  (1)
    • Multimedia  (6)
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  • Article

Trends and Predictors of Biomedical Research Quality, 1990–2015: A Meta-Research Study

By: Maryaline Catillon
Keywords: Biomedical Research; R&D; Innovation; Technology; Drug Trials; RCT; Health; Healthcare; Health Care And Treatment; Health Care Policy; Innovation and Invention; Innovation Strategy; Research and Development; Technological Innovation; Health Industry; Health Industry
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Catillon, Maryaline. "Trends and Predictors of Biomedical Research Quality, 1990–2015: A Meta-Research Study." BMJ Open 9, no. 9 (September 2019).
  • 15 Aug 2024
  • Op-Ed

Post-CrowdStrike, Six Questions to Test Your Company's Operational Resilience

When cybersecurity firm CrowdStrike distributed a faulty software update in July, it impacted a staggering 8.5 million devices. The crisis rippled through commercial airline operations, package delivery logistics, ecommerce, and View Details
Keywords: by Hise Gibson and Anita Lynch
  • August 13, 2022
  • Article

A Historic Opportunity for Universal Health Coverage in India

By: Vikram Patel, Shubhangi Bhadada, Kiran Mazumdar-Shaw, Arnab Mukherji, Tarun Khanna and Gagandeep Kang
The milestone of India's 75th anniversary of independence on Aug 15, 2022, offers an opportunity to reassert the country's commitment to realising universal health coverage (UHC). The first such effort predates independence, with the 1946 Bhore Committee report.... View Details
Keywords: Universal Health Coverage; COVID-19 Pandemic; Health Care and Treatment; Gender; Prejudice and Bias; Health Industry; India
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Patel, Vikram, Shubhangi Bhadada, Kiran Mazumdar-Shaw, Arnab Mukherji, Tarun Khanna, and Gagandeep Kang. "A Historic Opportunity for Universal Health Coverage in India." Lancet 400, no. 10351 (August 13, 2022): 475–477.
  • January 23, 2023
  • Article

Digital Public Health Interventions at Scale: The Impact of Social Media Advertising on Beliefs and Outcomes Related to COVID Vaccines

By: Susan Athey, Kristen Grabarz, Michael Luca and Nils Wernerfelt
Public health organizations increasingly use social media advertising campaigns in pursuit of public health goals. In this paper, we evaluate the impact of about $40 million of social media advertisements that were run and experimentally tested on Facebook and... View Details
Keywords: COVID-19 Pandemic; Public Health; Vaccines; Social Media; Advertising; Power and Influence; Health Care and Treatment
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Athey, Susan, Kristen Grabarz, Michael Luca, and Nils Wernerfelt. "Digital Public Health Interventions at Scale: The Impact of Social Media Advertising on Beliefs and Outcomes Related to COVID Vaccines." e2208110120. Proceedings of the National Academy of Sciences 120, no. 5 (January 23, 2023).
  • Article

Quantifying the Use of Connected Digital Products in Clinical Research

By: Caroline Marra, Jacqueline L. Chen, Andrea Coravos and Ariel D. Stern
Over recent years, the adoption of connected technologies has grown dramatically, with potential for improving health care delivery, research, and patient experience. Yet, little has been documented about the prevalence and use of connected digital products (e.g.,... View Details
Keywords: Connected Digital Products; Clinical Trials; Health Testing and Trials; Information Technology; Research
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Marra, Caroline, Jacqueline L. Chen, Andrea Coravos, and Ariel D. Stern. "Quantifying the Use of Connected Digital Products in Clinical Research." Art. 50. npj Digital Medicine 3 (2020).
  • 17 Sep 2021
  • Research & Ideas

The Trial of Elizabeth Holmes: Visionary, Criminal, or Both?

Former Theranos employees began testifying this week against Elizabeth Holmes, the once-celebrated biotech’s founder and CEO, in a criminal trial that has Silicon Valley worried. In opening statements last... View Details
Keywords: by Christina Pazzanese, Harvard Gazette; Biotechnology; Technology; Medical Devices & Supplies
  • January 17, 2022
  • Article

Reducing Racial Disparities in Cancer Outcomes

By: Kathy Giusti and Richard G. Hamermesh
A disproportionate number of Black patients die from cancer in the United States. A key to addressing this problem is enrolling more Black patients in clinical trials. A strategy consisting of these three parts can help accomplish this goal: 1) centralize information... View Details
Keywords: Cancer Trials; Racial Disparity; Health Testing and Trials; Race; Strategy
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Giusti, Kathy, and Richard G. Hamermesh. "Reducing Racial Disparities in Cancer Outcomes." Harvard Business Review (website) (January 17, 2022).
  • 2024
  • Working Paper

HIV Tests and AIDS Treatments—Containing a Fearsome Pandemic: Case Histories of Transformational Advances

By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins
This case history describes how a diverse cast of characters, including public health organizations, research laboratories, for-profit healthcare companies, activists, and regulators, rolled back the outbreak of HIV/AIDS in just fifteen years. Moreover, as the case... View Details
Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms
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Bhidé, Amar, Srikant M. Datar, and Katherine Stebbins. "HIV Tests and AIDS Treatments—Containing a Fearsome Pandemic: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 20-007, July 2019. (Revised May 2024.)
  • July 2021
  • Article

Making Medications Stick: Improving Medication Adherence by Highlighting the Personal Health Costs of Non-compliance

By: Jon M. Jachimowicz, Joe J. Gladstone, Dan Berry, Charlotte L. Kirkdale, Tracey Thornley and Adam D. Galinsky
Poor compliance of prescription medication is an ongoing public health crisis. Nearly half of patients do not take their medication as prescribed, harming their own health while also increasing public health care costs. Despite these detrimental consequences, prior... View Details
Keywords: Prescription Drugs; Medication Adherence; Personal Health Costs; Health; Behavior; Motivation and Incentives; Communication Strategy
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Jachimowicz, Jon M., Joe J. Gladstone, Dan Berry, Charlotte L. Kirkdale, Tracey Thornley, and Adam D. Galinsky. "Making Medications Stick: Improving Medication Adherence by Highlighting the Personal Health Costs of Non-compliance." Behavioural Public Policy 5, no. 3 (July 2021): 396–416.
  • Article

National Trends in the Safety Performance of Electronic Health Record Systems From 2009 to 2018

By: David Classen, A Jay Holmgren, Zoe Co, Lisa Newmark, Diane Seger, Melissa Danforth and David Bates
Importance Despite the broad adoption of electronic health record (EHR) systems across the continuum of care, safety problems persist. Objective To measure the safety performance of operational EHRs in hospitals across the country during a 10-year period. Design,... View Details
Keywords: Electronic Health Record Systems; Health Care and Treatment; Information Technology; Performance; Safety; Measurement and Metrics; United States
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Classen, David, A Jay Holmgren, Zoe Co, Lisa Newmark, Diane Seger, Melissa Danforth, and David Bates. "National Trends in the Safety Performance of Electronic Health Record Systems From 2009 to 2018." JAMA Network Open 3, no. 5 (May 2020).
  • December 2007
  • Article

Regional Health Information Organizations: Current Activities and Financing

Electronic clinical data exchange promises substantial financial and societal benefits, but it is unclear whether and when it will become widespread. In early 2007 we surveyed 145 regional health information organizations (RHIOs), the U.S. entities working to establish... View Details
Keywords: Information Technology; Financing and Loans; Health Care and Treatment; Information Management; Health Industry; United States
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Adler-Milstein, Julia Rose, Andrew McAfee, David Bates, and Ashish Jha. "Regional Health Information Organizations: Current Activities and Financing." Web Exclusive Health Affairs (December 2007): w60–w69.
  • 1984
  • Book

The Results and Interpretation of Three Field Trials of Lysine Fortification of Cereals

By: James E. Austin, Jean Pierre Habicht, Max Milner, Vernon Young and Linda D. Myers
Keywords: Food; Nutrition
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Austin, James E., Jean Pierre Habicht, Max Milner, Vernon Young, and Linda D. Myers. The Results and Interpretation of Three Field Trials of Lysine Fortification of Cereals. Washington, D.C.: National Academy Press, 1984.
  • Article

Use of Connected Digital Products in Clinical Research Following the COVID-19 Pandemic: A Comprehensive Analysis of Clinical Trials

By: Caroline Marra, William J. Gordon and Ariel Dora Stern
Objectives: In an effort to mitigate COVID-19 related challenges for clinical research, the U.S. Food and Drug Administration (FDA) issued new guidance for the conduct of ‘virtual’ clinical trials in late March 2020. This study documents trends in the use of... View Details
Keywords: Connected Digital Products; Telehealth; Remote Monitoring; Health Testing and Trials; Research; Governing Rules, Regulations, and Reforms; Information Technology
Citation
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Marra, Caroline, William J. Gordon, and Ariel Dora Stern. "Use of Connected Digital Products in Clinical Research Following the COVID-19 Pandemic: A Comprehensive Analysis of Clinical Trials." BMJ Open 11, no. 6 (2021).
  • January 2020
  • Article

Assessing the Safety of Electronic Health Records: A National Longitudinal Study of Medication-related Decision Support

By: A Jay Holmgren, Zoe Co, Lisa Newmark, Melissa Danforth, David Classen and David Bates
Background Electronic health records (EHR) can improve safety via computerised physician order entry with clinical decision support, designed in part to alert providers and prevent potential adverse drug events at entry and before they reach the patient.... View Details
Keywords: Hospital; Electronic Health Records; Health Care and Treatment; Information Technology; Safety; Performance; Quality; Performance Improvement
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Holmgren, A Jay, Zoe Co, Lisa Newmark, Melissa Danforth, David Classen, and David Bates. "Assessing the Safety of Electronic Health Records: A National Longitudinal Study of Medication-related Decision Support." BMJ Quality & Safety 29, no. 1 (January 2020): 52–59.
  • February 2008 (Revised August 2008)
  • Case

EXACT Sciences Corp.: Commercializing a Diagnostic Test

By: Regina E. Herzlinger
This case addresses the challenges of commercializing molecular diagnostics. Along the way, it explains the technology, payment system, and the measures used to assess the value of a diagnostic test. View Details
Keywords: Health Testing and Trials; Genetics; Science-Based Business; Commercialization; Biotechnology Industry
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Herzlinger, Regina E. "EXACT Sciences Corp.: Commercializing a Diagnostic Test." Harvard Business School Case 308-090, February 2008. (Revised August 2008.)
  • Article

Financial Incentive Based Approaches for Weight Loss: A Randomized Trial

By: Kevin Volpp, Leslie K. John, Andrea Troxel, Laurie Norton, Jennifer Fassbender and George Loewenstein
Keywords: Finance; Health; Motivation and Incentives
Citation
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Volpp, Kevin, Leslie K. John, Andrea Troxel, Laurie Norton, Jennifer Fassbender, and George Loewenstein. "Financial Incentive Based Approaches for Weight Loss: A Randomized Trial." JAMA, the Journal of the American Medical Association 300, no. 22 (December 10, 2008): 2631–2637.
  • April 1, 2020
  • Article

Coronavirus Is Putting Corporate Social Responsibility to the Test

By: Mark R. Kramer
A great many large companies talk about their values, or about how much they care for their employees and other stakeholders. The coronavirus crisis is the time for them to make good on that commitment. The author offers some things that corporations can do to help... View Details
Keywords: Health Pandemics; Corporate Social Responsibility and Impact
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Kramer, Mark R. "Coronavirus Is Putting Corporate Social Responsibility to the Test." Harvard Business Review Digital Articles (April 1, 2020).
  • June 2011
  • Article

Financial Incentives for Extended Weight Loss: A Randomized, Controlled Trial

By: Leslie K. John, George Loewenstein, Andrea Troxel, Laurie Norton, Jennifer Fassbender and Kevin Volpp
Keywords: Finance; Health; Motivation and Incentives
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John, Leslie K., George Loewenstein, Andrea Troxel, Laurie Norton, Jennifer Fassbender, and Kevin Volpp. "Financial Incentives for Extended Weight Loss: A Randomized, Controlled Trial." Journal of General Internal Medicine 26, no. 6 (June 2011): 621–626.
  • January 2007
  • Article

A Randomized Clinical Trial of EMDR, Fluoxetine and Pill Placebo in the Treatment of PTSD: Treatment Effects and Long-term Maintenance

By: Bessel A. van der Kolk, Joseph Spinazzola, Margaret E. Blaustein, James Hopper, Elizabeth Hopper, Deborah Korn and William B. Simpson
Keywords: Health Testing and Trials; Health Care and Treatment; Health Disorders
Citation
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van der Kolk, Bessel A., Joseph Spinazzola, Margaret E. Blaustein, James Hopper, Elizabeth Hopper, Deborah Korn, and William B. Simpson. "A Randomized Clinical Trial of EMDR, Fluoxetine and Pill Placebo in the Treatment of PTSD: Treatment Effects and Long-term Maintenance." Journal of Clinical Psychiatry 68, no. 1 (January 2007).
  • October 2015
  • Case

DPDHL Group: Employee Safety and Wellbeing

By: John A. Quelch and Carin-Isabel Knoop
Management at Deutsche Post DHL Group is designing a three-country test of investment in a new health and wellbeing strategy. View Details
Keywords: Health; Wellbeing; Wellness; Safety; Risk; Employees; Human Resources; Risk Management; Service Industry; China; Mexico; Middle East
Citation
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Quelch, John A., and Carin-Isabel Knoop. "DPDHL Group: Employee Safety and Wellbeing." Harvard Business School Case 516-049, October 2015.
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