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    • All HBS Web  (225)
      • Faculty Publications  (98)

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      • July 31, 2017
      • Article

      A Commitment Contract to Achieve Virologic Suppression in Poorly Adherent Patients with HIV/AIDS

      By: Marcella Alsan, John Beshears, Wendy S. Armstrong, James J. Choi, Brigitte C. Madrian, Minh Ly T. Nguyen, Carlos Del Rio, David Laibson and Vincent C. Marconi
      Objective: Assess whether a commitment contract informed by behavioral economics leads to persistent virologic suppression among HIV-positive patients with poor antiretroviral therapy (ART) adherence. Design: Single-center pilot randomized clinical trial and a... View Details
      Keywords: Adherence; Antiretroviral Therapy; Behavioral Economics; Commitment Contract; Financial Incentives; HIV-1 Virologic Suppression; Health Disorders; Motivation and Incentives
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      Alsan, Marcella, John Beshears, Wendy S. Armstrong, James J. Choi, Brigitte C. Madrian, Minh Ly T. Nguyen, Carlos Del Rio, David Laibson, and Vincent C. Marconi. "A Commitment Contract to Achieve Virologic Suppression in Poorly Adherent Patients with HIV/AIDS." AIDS 31, no. 12 (July 31, 2017): 1765–1769.
      • June 2017
      • Article

      A Systematic Approach to Discussing Active Surveillance with Patients with Low-risk Prostate Cancer

      By: Behfar Ehdaie, Melissa Assel, Nicole Benfante, Deepak Malhotra and Andrew Vickers
      A systematic approach to counseling—using appropriate framing techniques derived from principles studied by negotiation scholars—can be taught to physicians in a one-hour lecture. We found evidence that even this minimal intervention can decrease overtreatment of... View Details
      Keywords: Health Care and Treatment; Health Disorders; Service Delivery; Negotiation; Health Industry
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      Ehdaie, Behfar, Melissa Assel, Nicole Benfante, Deepak Malhotra, and Andrew Vickers. "A Systematic Approach to Discussing Active Surveillance with Patients with Low-risk Prostate Cancer." European Urology 71, no. 6 (June 2017): 866–871.
      • Article

      One Obstacle to Curing Cancer: Patient Data Isn't Shared

      By: Richard G. Hamermesh and Kathy Giusti
      Precision Medicine requires large datasets to identify the mutations that lead to various cancers. Currently, genomic information is hoarded in fragmented silos within numerous academic medical centers, pharmaceutical companies, and some disease-based foundations. For... View Details
      Keywords: Healthcare; Technological And Scientific Innovation; Cancer Care In The U.S.; Cancer Treatment; Precision Medicine; Personalized Medicine; Data Sharing; Technological Innovation; Analytics and Data Science; Health Disorders; Medical Specialties; Research and Development; Customization and Personalization; Health Industry; United States
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      Hamermesh, Richard G., and Kathy Giusti. "One Obstacle to Curing Cancer: Patient Data Isn't Shared." Harvard Business Review (website) (November 28, 2016).
      • October 2016
      • Case

      Addicaid: Scaling a Digital Platform for Addiction Wellness and Recovery

      By: Robert S. Huckman and Sarah Mehta
      In 2013, Sam Frons founded Addicaid—a mobile application (app) that allowed people in addiction recovery to track their progress, check in with counselors, and connect with others in recovery programs. The app was grounded in cognitive behavioral therapy and used the... View Details
      Keywords: Digital Health Interventions; Substance Use Disorder; Addiction Treatment; Addiction Recovery; Scale; Innovation; Health; Health Disorders; Health Industry; New York (city, NY)
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      Huckman, Robert S., and Sarah Mehta. "Addicaid: Scaling a Digital Platform for Addiction Wellness and Recovery." Harvard Business School Case 617-018, October 2016.
      • October 2016 (Revised November 2016)
      • Case

      Innovating Beyond Ochsner

      By: Richard G. Hamermesh and Olivia Hull
      The Ochsner Health System has developed a proprietary software tool designed to treat hypertension. Built into the system’s electronic medical records, the Hypertension Digital Medicine program allows patients to record their blood pressure at home and share readings... View Details
      Keywords: Electronic Medical Records; Telemedicine; Hypertension; High Blood Pressure; Chronic Disease; Entrepreneurship; Health Disorders; Business Model; Business Startups; Innovation and Invention; Growth Management; Marketing Strategy; Product Launch; Product Positioning; Science-Based Business; Business Strategy; Health Industry; Health Industry; New Orleans; Louisiana
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      Hamermesh, Richard G., and Olivia Hull. "Innovating Beyond Ochsner." Harvard Business School Case 817-028, October 2016. (Revised November 2016.)
      • February 2016 (Revised September 2017)
      • Case

      Neurotrack and the Alzheimer's Puzzle

      By: Richard G. Hamermesh, Liz Kind and Carin-Isabel Knoop
      Elli Kaplan founded Neurotrack in 2012 with a breakthrough noninvasive cognitive diagnostics test that will detect Alzheimer's disease in its earliest pre-symptomatic stages. While the company has gained great traction in the three years since it was started, with no... View Details
      Keywords: Alzheimer's Disease; Diagnostics; Healthcare; Entrepreneurship; Health Disorders; Science-Based Business; Business Model; Medical Devices and Supplies Industry; United States
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      Hamermesh, Richard G., Liz Kind, and Carin-Isabel Knoop. "Neurotrack and the Alzheimer's Puzzle." Harvard Business School Case 816-072, February 2016. (Revised September 2017.)
      • Article

      Time-driven Activity-based Costing of Multivessel Coronary Artery Bypass Grafting across National Boundaries to Identify Improvement Opportunities: Study Protocol

      By: F. Erhun, B. Mistry, T. Platcheck, A. Milstein, V.G. Narayanan and R. S. Kaplan
      Coronary artery bypass graft (CABG) surgery is a common treatment for coronary artery disease—a disease that affects over 10% of US adults and is a major cause of morbidity and mortality. In 2005, the mean cost for a CABG procedure among Medicare beneficiaries in the... View Details
      Keywords: Activity Based Costing and Management; Health Disorders; Health Care and Treatment; United States; India
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      Erhun, F., B. Mistry, T. Platcheck, A. Milstein, V.G. Narayanan, and R. S. Kaplan. "Time-driven Activity-based Costing of Multivessel Coronary Artery Bypass Grafting across National Boundaries to Identify Improvement Opportunities: Study Protocol." BMJ Open 5, no. 8 (2015).
      • Article

      Patterns of Failure after Involved Field Radiation Therapy for Pediatric and Young Adult Hodgkin Lymphoma

      By: Minh-Phuong Huynh-Le, Amanda J. Walker, Scott Duke Kominers, Ido Paz-Priel, Moody D. Wharam and Stephanie A. Terezakis
      Involved field radiation therapy (IFRT) is integral in curative therapy for Hodgkin lymphoma (HL), although primarily used in patients with intermediate/high‐risk HL. We present failure patterns and clinical outcomes in a cohort of pediatric and young adult patients... View Details
      Keywords: Hematology/oncology; Hodgkin Lymphoma; Involved Field Radiation Therapy; Health Disorders; Health Care and Treatment
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      Huynh-Le, Minh-Phuong, Amanda J. Walker, Scott Duke Kominers, Ido Paz-Priel, Moody D. Wharam, and Stephanie A. Terezakis. "Patterns of Failure after Involved Field Radiation Therapy for Pediatric and Young Adult Hodgkin Lymphoma." Pediatric Blood & Cancer 61, no. 7 (July 2014).
      • June 2014 (Revised April 2015)
      • Case

      OrthoChoice: Bundled Payments in the County of Stockholm (A)

      By: Michael E. Porter, Clifford M. Marks and Zachary C. Landman
      It was the waiting that drew the attention of the Stockholm County Council. In 2008, patients seeking a hip or knee replacement in Stockholm County faced wait times of up to two years of sometimes debilitating pain, intermittent missed work and income, and the trials... View Details
      Keywords: Bundled Payment; Health Care Quality; Health Care; Sweden; Hip Replacement; Knee Replacement; Orthopedics; Health Care and Treatment; Health Disorders; Health; Health Industry; Sweden
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      Porter, Michael E., Clifford M. Marks, and Zachary C. Landman. "OrthoChoice: Bundled Payments in the County of Stockholm (A)." Harvard Business School Case 714-514, June 2014. (Revised April 2015.)
      • June 2014 (Revised April 2015)
      • Supplement

      OrthoChoice: Bundled Payments in the County of Stockholm (B)

      By: Michael E. Porter, Clifford M. Marks and Zachary C. Landman
      By the end of 2008, all major hospitals (one of which was private) and three private specialized orthopedic centers signed OrthoChoice contracts. In 2009, hip and knee replacements in the County of Stockholm for relatively healthy patients began being reimbursed. By... View Details
      Keywords: Hip Replacement; Bundled Payment; Knee Replacement; Value Agenda; Strategy; Health Care Industry; Health; Health Care and Treatment; Health Disorders; Health Industry; Sweden
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      Porter, Michael E., Clifford M. Marks, and Zachary C. Landman. "OrthoChoice: Bundled Payments in the County of Stockholm (B)." Harvard Business School Supplement 714-515, June 2014. (Revised April 2015.)
      • January 2014
      • Teaching Note

      Dr. Benjamin Hooks and Children's Health Forum

      By: Rosabeth Moss Kanter and Ai-Ling Malone
      The case includes law, business, and public health perspectives on an African American leader's social entrepreneurship and leadership in other social movements. Later in his life, Dr. Benjamin Hooks championed the eradication of lead poisoning. Prior to that Hooks... View Details
      Keywords: Leading Change; Health Disorders; Social Entrepreneurship; Personal Development and Career; Social Issues; United States
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      Kanter, Rosabeth Moss, and Ai-Ling Malone. "Dr. Benjamin Hooks and Children's Health Forum." Harvard Business School Teaching Note 314-092, January 2014.
      • Article

      Experiments in Open Innovation at Harvard Medical School

      By: Eva C. Guinan, Kevin J. Boudreau and Karim R. Lakhani
      Harvard Medical School seems an unlikely organization to open up its innovation process. By most measures, the more than 20,000 faculty, research staff and graduate students affiliated with Harvard Medical School are already world class and at the top of the medical... View Details
      Keywords: Health Disorders; Collaborative Innovation and Invention; Boston
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      Guinan, Eva C., Kevin J. Boudreau, and Karim R. Lakhani. "Experiments in Open Innovation at Harvard Medical School." Art. 3. MIT Sloan Management Review 54, no. 3 (Spring 2013): 45–52.
      • December 2012 (Revised November 2014)
      • Case

      W.R. Grace & Co.: Dealing with Asbestos Torts

      By: Stuart C. Gilson and Sarah L. Abbott
      A manufacturer of building products and specialty chemicals, W. R. Grace & Co. filed for Chapter 11 bankruptcy in 2001 in response to a flood of lawsuits alleging that its products contained asbestos, and had caused hundreds of thousands of people to contract... View Details
      Keywords: Bankruptcy Reorganization; Business Failures; Environmental Regulations; Class Action Lawsuits; Natural Environment; Valuation; Health Disorders; Capital Structure; Restructuring; Lawsuits and Litigation; Chemicals; Crisis Management; Insolvency and Bankruptcy; Legal Liability; Construction Industry; Chemical Industry; United States
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      Gilson, Stuart C., and Sarah L. Abbott. "W.R. Grace & Co.: Dealing with Asbestos Torts." Harvard Business School Case 213-046, December 2012. (Revised November 2014.)
      • September 2012
      • Case

      SCMS: Battling HIV/AIDS in Africa

      By: Ananth Raman, Noel Watson, Santiago Kraiselburd and Emmanuel Akili
      In 2005, USAID and the U.S. President's Emergency Plan for AIDS Relief (PEPFAR), created the Supply Chain Management System (SCMS) to procure and distribute essential medicines and supplies; provide technical assistance to transform existing supply chains; and... View Details
      Keywords: HIV; AIDS; Procurement Coordination; Developing Countries; Healthcare; Public Health; Ethiopia; Supply Systems For Healthcare Delivery In Developing Countries; Healthcare Logistics Industry; Health Disorders; Health Care and Treatment; Service Delivery; Supply Chain Management; Logistics; Developing Countries and Economies; Programs; Transition; Strategy; Health Industry; Health Industry; Ethiopia; Africa
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      Raman, Ananth, Noel Watson, Santiago Kraiselburd, and Emmanuel Akili. "SCMS: Battling HIV/AIDS in Africa." Harvard Business School Case 613-023, September 2012.
      • August 2012 (Revised February 2021)
      • Case

      Hub and Spoke, HealthCare Global and Additional Focused Factory Models for Cancer Care

      By: Regina E. Herzlinger, Amit Ghorawat, Meera Krishnan and Naiyya Saggi
      This case compares and contrasts four different models for delivering cancer care in India and the US. Students are asked to select the best model in its alignment with the Six Forces in those two countries and Africa, to which one of the models is considering... View Details
      Keywords: Cancer Care Services; Focused Factories For Cancer Care; Hub And Spoke Cancer Care; Cancer Care In The U.S.; Cancer Care In Africa; Cancer Care In India; Health Care and Treatment; Business Model; Six Sigma; Health Disorders; Health Industry; United States; India; Africa
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      Herzlinger, Regina E., Amit Ghorawat, Meera Krishnan, and Naiyya Saggi. "Hub and Spoke, HealthCare Global and Additional Focused Factory Models for Cancer Care." Harvard Business School Case 313-030, August 2012. (Revised February 2021.)
      • August 2012 (Revised August 2014)
      • Case

      Cancer Treatment Centers of America® (A)

      By: Regina E. Herzlinger and Natalie Kindred
      Cancer Treatment Centers of America (CTCA), a U.S. network of four privately owned oncology focused factory hospitals, was weighing options for growth. CTCA was entirely cancer focused and specialized in treating patients with complex and advanced-stage cancers, who... View Details
      Keywords: Cancer; Cancer Treatment; Health Care; Healthcare; Accountability; Outcomes; Outcomes Measurement; Outcomes Reporting; Hub And Spoke Cancer Care; Hub And Spoke; Hub-and-spoke; Focused Factory; Mission and Purpose; Private Ownership; For-Profit Firms; Health Disorders; Medical Specialties; Policy; Business Model; Expansion; Decision Choices and Conditions; Advertising; Health Care and Treatment; Innovation and Invention; Health Industry; United States
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      Herzlinger, Regina E., and Natalie Kindred. "Cancer Treatment Centers of America® (A)." Harvard Business School Case 313-012, August 2012. (Revised August 2014.)
      • March 2012 (Revised April 2013)
      • Case

      Schön Klinik: Eating Disorder Care

      By: Michael E. Porter, Emma Stanton, Jessica A. Hohman and Caleb Stowell
      The Schön Klinik is a private, for-profit German hospital group trying to establish itself as a premium health care provider in a competitive German market. The case details Schön Klinik's founding, its early focus on measurement and improvement, and the design and... View Details
      Keywords: Health Care Quality; Outcomes; Quality Improvement; Strategy And Performance Measurement; Integration; Measurement and Metrics; Competition; Health Disorders; Health Care and Treatment; Outcome or Result; Performance Evaluation; Business Processes; Health Industry; Germany
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      Porter, Michael E., Emma Stanton, Jessica A. Hohman, and Caleb Stowell. "Schön Klinik: Eating Disorder Care." Harvard Business School Case 712-475, March 2012. (Revised April 2013.)
      • June 2011
      • Teaching Note

      PatientsLikeMe: An Online Community of Patients (TN)

      By: Sunil Gupta and Jason Riis
      Teaching Note for 511093. View Details
      Keywords: Internet and the Web; Social and Collaborative Networks; Health Disorders; Growth and Development; Product Launch; Web Services Industry
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      Gupta, Sunil, and Jason Riis. "PatientsLikeMe: An Online Community of Patients (TN)." Harvard Business School Teaching Note 511-138, June 2011.
      • February 2011 (Revised November 2012)
      • Case

      PatientsLikeMe: An Online Community of Patients

      By: Sunil Gupta and Jason Riis
      PatientsLikeMe (PLM) is an online community where patients share their personal experiences with a disease, find other patients like them, and learn from each other. The company was founded by Jamie and Ben Heywood when their 29-year-old brother was diagnosed with ALS... View Details
      Keywords: Business Startups; Health Disorders; Knowledge Sharing; Growth and Development Strategy; Product Launch; Digital Platforms; Social and Collaborative Networks; Health Industry
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      Gupta, Sunil, and Jason Riis. "PatientsLikeMe: An Online Community of Patients." Harvard Business School Case 511-093, February 2011. (Revised November 2012.)
      • August 2010 (Revised January 2013)
      • Case

      Avi Kremer

      By: Joshua D. Margolis and Mark Wetzel
      If you were diagnosed with a terminal illness, how would you respond and what would you do with your remaining time? Avi Kremer contemplates four options for how to devote himself 18 months after being diagnosed with ALS. His experience thus far and the choices he... View Details
      Keywords: Entrepreneurship; Values and Beliefs; Health Disorders; Leadership Development; Personal Development and Career; Social Enterprise; Personal Characteristics
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      Margolis, Joshua D., and Mark Wetzel. "Avi Kremer." Harvard Business School Case 411-022, August 2010. (Revised January 2013.)
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