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  • October 2003 (Revised February 2004)
  • Case

Launching the European Food Safety Authority

By: Ray A. Goldberg and Hal Hogan
The first food safety commission is established for the European Union. How does it handle food safety, scientific evaluations, and people's attitudes toward scientific changes in food growing and processing--for example, genetically modified organisms? View Details
Keywords: Food; Safety; Nutrition; Policy; Food and Beverage Industry; European Union
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Goldberg, Ray A., and Hal Hogan. "Launching the European Food Safety Authority." Harvard Business School Case 904-414, October 2003. (Revised February 2004.)
  • April 2001 (Revised January 2003)
  • Case

Robert Shapiro and Monsanto

Traces Monsanto's efforts to become a global biotech powerhouse under Shapiro's leadership. Examines how his crusade to save the world through genetic modification foundered. View Details
Keywords: Genetics; Supply Chain Management; Alliances; Global Strategy; Cross-Cultural and Cross-Border Issues; Biotechnology Industry
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Watkins, Michael D., and Ann Leamon. "Robert Shapiro and Monsanto." Harvard Business School Case 801-426, April 2001. (Revised January 2003.)
  • October 2001
  • Case

TIGR and ILRI: Solving Problems with Genomics

By: Ray A. Goldberg and James M Beagle
Discusses nonprofit institutional leadership applying advances in genetic science to solve health and animal problems in industrial countries and the developing world. View Details
Keywords: Developing Countries and Economies; Health; Technological Innovation; Leading Change; Emerging Markets; Genetics; Non-Governmental Organizations; Technology Adoption; Biotechnology Industry
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Goldberg, Ray A., and James M Beagle. "TIGR and ILRI: Solving Problems with Genomics." Harvard Business School Case 902-409, October 2001.
  • February 2006 (Revised August 2006)
  • Case

deCODE Genetics: Hunting for Genes to Develop Drugs

By: Debora L. Spar
In 1996, Kari Stefansson launched a new kind of biotechnology company and a whole new way of attacking diseases. Based in Iceland, his firm, deCODE Genetics, plans to identify the individual genetic markers that lead to society's most prevalent diseases. To do so, it... View Details
Keywords: Information; Innovation Strategy; Genetics; Ethics; Health Disorders; Biotechnology Industry; Iceland
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Spar, Debora L., and Chris Bebenek. "deCODE Genetics: Hunting for Genes to Develop Drugs." Harvard Business School Case 706-040, February 2006. (Revised August 2006.)
  • 09 Apr 2012
  • Research & Ideas

Who Sways the USDA on GMO Approvals?

asking that question through research on the controversial issue of genetically modified organisms (GMOs), agricultural products that are genetically altered to increase yield, incorporate pesticide... View Details
Keywords: by Michael Blanding; Food & Beverage; Biotechnology; Agriculture & Agribusiness
  • April 2019
  • Teaching Note

The a2 Milk Company

By: Benjamin C. Esty and Daniel Fisher
The a2 Milk Company (a2MC) became the most valuable company listed on the New Zealand stock exchange in 2018 by capitalizing on a biochemical discovery related to the protein composition of cow's milk. Because many people find the A1 protein difficult to digest, and... View Details
Keywords: Judo Economics; Market Entry; Innovation; Barriers To Response; Industry Attractiveness; Advantage Horizon; Sustainability; First-mover Advantage; Scope; Strategy Execution; Strategic Evolution; Biochemistry; Genetics; Branding; Commodity; Milk; Dairy; Infant Formula; Farming; Porter's Five Forces; Market Entry and Exit; Disruption; Innovation and Invention; Competitive Advantage; Corporate Strategy; Value Creation; Competition; Brands and Branding; Five Forces Framework; Consumer Products Industry; New Zealand; Australia; China
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Esty, Benjamin C., and Daniel Fisher. "The a2 Milk Company." Harvard Business School Teaching Note 719-428, April 2019.
  • January 2014 (Revised December 2014)
  • Case

GenapSys: Business Models for the Genome

By: Richard G. Hamermesh, Joseph B. Fuller and Matthew Preble

GenapSys, a California-based startup, was soon to release a new DNA sequencer that the company's founder, Hesaam Esfandyarpour, believed was truly revolutionary. The sequencer would be substantially less expensive—potentially costing just a few thousand dollars—and... View Details

Keywords: DNA Sequencing; Life Sciences; Business Model; Innovation & Entrepreneurship; Health Care and Treatment; Genetics; Business Strategy; Biotechnology Industry; Pharmaceutical Industry; Technology Industry; Health Industry; Medical Devices and Supplies Industry; United States
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Hamermesh, Richard G., Joseph B. Fuller, and Matthew Preble. "GenapSys: Business Models for the Genome." Harvard Business School Case 814-050, January 2014. (Revised December 2014.)
  • January 2019 (Revised February 2019)
  • Supplement

The a2 Milk Company

By: Benjamin C. Esty, Daniel Fisher and Greg Saldutte
The a2 Milk Company (a2MC) became the most valuable company listed on the New Zealand stock exchange in 2018 by capitalizing on a biochemical discovery related to the protein composition of cow's milk. Because many people find the A1 protein difficult to digest, and... View Details
Keywords: Judo Economics; Market Entry; Innovation; Barriers To Response; Industry Attractiveness; Advantage Horizon; Sustainability; First-mover Advantage; Scope; Strategy Execution; Strategic Evolution; Biochemistry; Genetics; Branding; Commodity; Milk; Dairy; Infant Formula; Farming; Porter's Five Forces; Competitive Advantage; Corporate Strategy; Value Creation; Competition; Market Entry and Exit; Disruption; Innovation and Invention; Five Forces Framework; Consumer Products Industry; New Zealand; Australia; China
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Esty, Benjamin C., Daniel Fisher, and Greg Saldutte. "The a2 Milk Company." Harvard Business School Spreadsheet Supplement 719-804, January 2019. (Revised February 2019.)
  • 28 Feb 2019
  • Cold Call Podcast

Pursuing Precision Medicine at Intermountain Healthcare

Keywords: Re: Richard G. Hamermesh; Health; Biotechnology; Pharmaceutical
  • October 2001 (Revised April 2002)
  • Case

Calgene, Inc.

By: Ray A. Goldberg and John T. Gourville
In 1993, Calgene is on the verge of introducing the world's first genetically engineered plant product--a tomato will taste better and stay fresh longer. At the same time, it is using biotechnology to produce improved plant products for the cottonseed and the... View Details
Keywords: Information Technology; Marketing Strategy; Market Entry and Exit; Product Launch; Innovation Strategy; Social Issues; Production; Problems and Challenges; Biotechnology Industry; Agriculture and Agribusiness Industry
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Goldberg, Ray A., and John T. Gourville. "Calgene, Inc." Harvard Business School Case 502-041, October 2001. (Revised April 2002.)
  • Summer 2018
  • Book Review

Leslie Berlin, Troublemakers: Silicon Valley's Coming of Age

By: William A. Sahlman
Leslie Berlin's book Troublemakers, is an engaging and insightful people-first exploration of the roots of Silicon Valley, from the late 1960s to the early 1980s. Berlin portrays seven individuals who played important roles at critical junctures in the... View Details
Keywords: Silicon Valley; Technological Innovation; Disruptive Innovation; History; California
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Sahlman, William A. "Leslie Berlin, Troublemakers: Silicon Valley's Coming of Age." Business History Review 92, no. 2 (Summer 2018): 343–353.
  • October 2002 (Revised February 2006)
  • Case

Codex Alimentarius and Food Labeling

By: Ray A. Goldberg and Hal Hogan
Codex Alimentarius is a set of international food standards devised by the Codex Commission, a body within the United Nations jointly sponsored by the FAO and WHO. The purpose of the standards is to harmonize global trade in food products and agricultural commodities,... View Details
Keywords: Standards; Trade; Agreements and Arrangements; Food; Agribusiness; Governing Rules, Regulations, and Reforms; Globalization; Health; Food and Beverage Industry; Agriculture and Agribusiness Industry
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Goldberg, Ray A., and Hal Hogan. "Codex Alimentarius and Food Labeling." Harvard Business School Case 903-417, October 2002. (Revised February 2006.)
  • December 2002 (Revised April 2007)
  • Case

Cargill (A)

By: Ray A. Goldberg and Jose M. M. Porraz
Cargill is one of the world's leading marketers, processors, and distributors of agricultural, food, industrial, and financial products. In 1998, the company decided to develop a strategic intent to restructure and refocus the company. It did so in response to the... View Details
Keywords: Business Strategy; Agribusiness; Restructuring; Industry Structures; Global Strategy; Genetics; Demand and Consumers; Agriculture and Agribusiness Industry
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Goldberg, Ray A., and Jose M. M. Porraz. "Cargill (A)." Harvard Business School Case 903-420, December 2002. (Revised April 2007.)
  • December 2005 (Revised August 2006)
  • Case

Amgen Inc.'s Epogen--Commercializing the First Biotech Blockbuster Drug

By: Felix Oberholzer-Gee and Dennis A. Yao
Amgen Inc.'s Epogen was the first biotech blockbuster drug. Epogen helped prevent anemia, a condition that leads to severe fatigue, increased risk of cardiovascular disease, and even death. At the time, the market for Epogen, which included dialysis patients and... View Details
Keywords: Health Care and Treatment; Strategic Planning; Competition; Patents; Innovation and Invention; Pharmaceutical Industry; Biotechnology Industry; United States
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Oberholzer-Gee, Felix, and Dennis A. Yao. "Amgen Inc.'s Epogen--Commercializing the First Biotech Blockbuster Drug." Harvard Business School Case 706-454, December 2005. (Revised August 2006.)
  • August 2001
  • Case

Finnigan Corporation

By: Carliss Y. Baldwin and Barbara Feinberg
Finnigan Corp., headquartered in San Jose, CA, was the world's leading producer of mass spectrometers, holding a 45% market share of instruments used for chemical analysis in pharmaceutical product development, environmental testing, genetic testing, and other... View Details
Keywords: Business Exit or Shutdown; Financial Crisis; Machinery and Machining; Technology Industry; San Jose
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Baldwin, Carliss Y., and Barbara Feinberg. "Finnigan Corporation." Harvard Business School Case 902-045, August 2001.
  • June 2016
  • Case

Alnylam: Building a Biotechnology Powerhouse

By: Kevin Schulman
Alnylam is an early stage biomedical technology focused on commercial development of a novel technology platform, siRNA. This technology offered promise to treat rare genetic disorders that could not be treated with other technologies. Alnlyam's development entailed... View Details
Keywords: Technological Innovation; Commercialization; Health Disorders; Intellectual Property; Biotechnology Industry
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Schulman, Kevin. "Alnylam: Building a Biotechnology Powerhouse." Harvard Business School Case 316-113, June 2016.
  • November 2007
  • Class Lecture

The Baby Business (FSS)

By: Debora L. Spar
In vitro fertilization and genetic screening are possible with the advent of biotechnology. International adoptions, surrogacy, and other approaches to family planning are on the rise. But few rules govern these measures, medical costs can be prohibitive, and... View Details
Keywords: Governing Rules, Regulations, and Reforms; Policy; Demand and Consumers; Business and Government Relations; Business and Stakeholder Relations; Genetics; Societal Protocols; Commercialization; Biotechnology Industry; Health Industry
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Spar, Debora L. "The Baby Business (FSS)." Harvard Business School Class Lecture 708-701, November 2007.
  • April 1998 (Revised January 2000)
  • Case

Pioneer Hi-Bred International, Inc.: Supply Management

By: Francis Aguilar, Paul Clark and Xin Xi He
This case depicts the supply-management practices--including planning, production, and distribution--at Pioneer Hi-Bred International, the world's leader in the genetically engineered hybrid crop-seed industry. Set in the context of a supply-management planning... View Details
Keywords: Plant-Based Agribusiness; Production; Distribution; Marketing Strategy; Customer Focus and Relationships; Logistics; Planning; Agriculture and Agribusiness Industry; Biotechnology Industry
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Aguilar, Francis, Paul Clark, and Xin Xi He. "Pioneer Hi-Bred International, Inc.: Supply Management." Harvard Business School Case 898-238, April 1998. (Revised January 2000.)
  • April 1993 (Revised May 1994)
  • Case

Genzyme Corporation: Strategic Challenges with Ceredase

Genzyme Corp., one of the largest biotechnology companies, has succeeded in developing, manufacturing, and commercializing its first therapeutic, a treatment for a rare genetic disease. Analysis of the case requires students to identify and understand how Genzyme has... View Details
Keywords: Risk Management; Risk and Uncertainty; Corporate Strategy; Technology; Health; Product Development; Biotechnology Industry; Pharmaceutical Industry; United States
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Teisberg, Elizabeth O., and Sharon L. Rossi. "Genzyme Corporation: Strategic Challenges with Ceredase." Harvard Business School Case 793-120, April 1993. (Revised May 1994.)
  • May 2020
  • Article

Ancient Origins of the Global Variation in Economic Preferences

By: Anke Becker, Benjamin Enke and Armin Falk
This paper shows that contemporary population-level heterogeneity in risk aversion, time preference, altruism, positive reciprocity, negative reciprocity, and trust partly traces back to the structure of the migration patterns of our very early ancestors. To document... View Details
Keywords: Migration Patterns; Behavioral Economics; Preferences; Microeconomics; Demography; Decision Making; Risk and Uncertainty; History; Global Range
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Becker, Anke, Benjamin Enke, and Armin Falk. "Ancient Origins of the Global Variation in Economic Preferences." AEA Papers and Proceedings 110 (May 2020): 319–323.
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