Publications
Publications
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- All HBS Web
(5,466)
- Faculty Publications (878)
- January 2024 (Revised April 2024)
- Case
Target Malaria: Editing Mosquitoes through Gene Drives
By: Shikhar Ghosh and Shweta Bagai
Target Malaria, a non-profit research consortium, is exploring the application of CRISPR-Cas9 gene editing technology to combat malaria in Sub-Saharan Africa. Its approach uses gene drives, a revolutionary tool, to suppress the population of malaria-carrying... View Details
- 2024
- Working Paper
Bootstrap Diagnostics for Irregular Estimators
By: Isaiah Andrews and Jesse M. Shapiro
Empirical researchers frequently rely on normal approximations in order to summarize and communicate uncertainty about their findings to their scientific audience. When such approximations are unreliable, they can lead the audience to make misguided decisions. We... View Details
- January 2024
- Article
Subset Scanning for Multi-Trait Analysis Using GWAS Summary Statistics
By: Rui Cao, Evan Olawsky, Edward McFowland III, Erin Marcotte, Logan Spector and Tianzhong Yang
Multi-trait analysis has been shown to have greater statistical power than single-trait analysis. Most of the existing multi-trait analysis methods only work with a limited number of traits and usually prioritize high statistical power over identifying relevant traits,... View Details
- December 2023
- Teaching Note
Viceroy Research versus Medical Properties Trust
By: Jonas Heese and Joseph Pacelli
Teaching Note for HBS Case No. 124-027. View Details
- 2023
- Article
Balancing Risk and Reward: An Automated Phased Release Strategy
By: Yufan Li, Jialiang Mao and Iavor Bojinov
Phased releases are a common strategy in the technology industry for gradually releasing new products or updates through a sequence of A/B tests in which the number of treated units gradually grows until full deployment or deprecation. Performing phased releases in a... View Details
- 2023
- Article
Post Hoc Explanations of Language Models Can Improve Language Models
By: Satyapriya Krishna, Jiaqi Ma, Dylan Slack, Asma Ghandeharioun, Sameer Singh and Himabindu Lakkaraju
Large Language Models (LLMs) have demonstrated remarkable capabilities in performing complex tasks. Moreover, recent research has shown that incorporating human-annotated rationales (e.g., Chain-of-Thought prompting) during in-context learning can significantly enhance... View Details
- 2023
- Other Article
The Harvard USPTO Patent Dataset: A Large-Scale, Well-Structured, and Multi-Purpose Corpus of Patent Applications
By: Mirac Suzgun, Luke Melas-Kyriazi, Suproteem K. Sarkar, Scott Duke Kominers and Stuart Shieber
Innovation is a major driver of economic and social development, and information about many kinds of innovation is embedded in semi-structured data from patents and patent applications. Though the impact and novelty of innovations expressed in patent data are difficult... View Details
- 2023
- Article
Verifiable Feature Attributions: A Bridge between Post Hoc Explainability and Inherent Interpretability
By: Usha Bhalla, Suraj Srinivas and Himabindu Lakkaraju
With the increased deployment of machine learning models in various real-world applications, researchers and practitioners alike have emphasized the need for explanations of model behaviour. To this end, two broad strategies have been outlined in prior literature to... View Details
- 2023
- Article
Which Models Have Perceptually-Aligned Gradients? An Explanation via Off-Manifold Robustness
By: Suraj Srinivas, Sebastian Bordt and Himabindu Lakkaraju
One of the remarkable properties of robust computer vision models is that their input-gradients are often aligned with human perception, referred to in the literature as perceptually-aligned gradients (PAGs). Despite only being trained for classification, PAGs cause... View Details
- 2023
- Working Paper
Coordinated R&D Programs and the Creation of New Industries
By: Daniel P. Gross and Maria P. Roche
Complex systems technologies—including “deep tech”—are prone to numerous frictions that stymie commercial development. Yet technologies with these features underpin some of the most valuable industries of the past century. We examine how large, mission-oriented... View Details
- October 2023
- Teaching Note
Timnit Gebru: 'SILENCED No More' on AI Bias and The Harms of Large Language Models
By: Tsedal Neeley and Tim Englehart
Teaching Note for HBS Case No. 422-085. Dr. Timnit Gebru—a leading artificial intelligence (AI) computer scientist and co-lead of Google’s Ethical AI team—was messaging with one of her colleagues when she saw the words: “Did you resign?? Megan sent an email saying that... View Details
- 2023
- Working Paper
Causal Interpretation of Structural IV Estimands
By: Isaiah Andrews, Nano Barahona, Matthew Gentzkow, Ashesh Rambachan and Jesse M. Shapiro
We study the causal interpretation of instrumental variables (IV) estimands of nonlinear, multivariate structural models with respect to rich forms of model misspecification. We focus on guaranteeing that the researcher's estimator is sharp zero consistent, meaning... View Details
Keywords: Mathematical Methods
- October 2023
- Article
Improving Regulatory Effectiveness Through Better Targeting: Evidence from OSHA
By: Matthew S. Johnson, David I. Levine and Michael W. Toffel
We study how a regulator can best target inspections. Our case study is a U.S. Occupational Safety and Health Administration (OSHA) program that randomly allocated some inspections. On average, each inspection averted 2.4 serious injuries (9%) over the next five years.... View Details
- 2023
- Working Paper
In-Context Unlearning: Language Models as Few Shot Unlearners
By: Martin Pawelczyk, Seth Neel and Himabindu Lakkaraju
Machine unlearning, the study of efficiently removing the impact of specific training points on the
trained model, has garnered increased attention of late, driven by the need to comply with privacy
regulations like the Right to be Forgotten. Although unlearning is... View Details
- September 2023
- Module Note
Live Case Exercise for Financial Reporting
By: Tatiana Sandino and Marshal Herrmann
Harvard Business School employs the case method as a cornerstone of its pedagogy, providing students with opportunities to engage in discussions related to difficult or contentious decisions confronted by real-world organizations. In this “live case,” we depart from... View Details
- September 2023 (Revised January 2024)
- Case
Helmy Abouleish: Making a Desert Bloom
By: Geoffrey G. Jones and Maxim Pike Harrell
This case examines the history of prominent Egyptian-based social enterprise SEKEM from its foundation in 1977 until the COP27 conference held in Sharm El-Sheikh in 2022. Led by father and son team Ibrahim and Helmy Abouleish, SEKEM turned desert into farmland using... View Details
- September–October 2023
- Article
Interpretable Matrix Completion: A Discrete Optimization Approach
By: Dimitris Bertsimas and Michael Lingzhi Li
We consider the problem of matrix completion on an n × m matrix. We introduce the problem of interpretable matrix completion that aims to provide meaningful insights for the low-rank matrix using side information. We show that the problem can be... View Details
Keywords: Mathematical Methods
- 2023
- Article
On Minimizing the Impact of Dataset Shifts on Actionable Explanations
By: Anna P. Meyer, Dan Ley, Suraj Srinivas and Himabindu Lakkaraju
The Right to Explanation is an important regulatory principle that allows individuals to request actionable explanations for algorithmic decisions. However, several technical challenges arise when providing such actionable explanations in practice. For instance, models... View Details
- July–August 2023
- Article
Demand Learning and Pricing for Varying Assortments
By: Kris Ferreira and Emily Mower
Problem Definition: We consider the problem of demand learning and pricing for retailers who offer assortments of substitutable products that change frequently, e.g., due to limited inventory, perishable or time-sensitive products, or the retailer’s desire to... View Details
- August 2023
- Article
Explaining Machine Learning Models with Interactive Natural Language Conversations Using TalkToModel
By: Dylan Slack, Satyapriya Krishna, Himabindu Lakkaraju and Sameer Singh
Practitioners increasingly use machine learning (ML) models, yet models have become more complex and harder to understand. To understand complex models, researchers have proposed techniques to explain model predictions. However, practitioners struggle to use... View Details