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      • November 2019
      • Supplement

      Hapag-Lloyd AG: Complying with IMO 2020

      By: Benjamin C. Esty, Mette Fuglsang Hjortshoej and Emer Moloney
      A new environmental regulation known as IMO 2020 was creating what one industry analyst called “the biggest shakeup for the oil and shipping industries in decades.” According to the new regulation, all ocean-going ships would have to limit their sulfur emissions by... View Details
      Keywords: Valuation; Ship Transportation; Strategic Planning; Game Theory; Pollutants; Supply Chain; Corporate Accountability; Capital Budgeting; Environmental Sustainability; Shipping Industry; Transportation Industry; Germany
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      Esty, Benjamin C., Mette Fuglsang Hjortshoej, and Emer Moloney. "Hapag-Lloyd AG: Complying with IMO 2020." Harvard Business School Spreadsheet Supplement 220-713, November 2019.
      • November 2019
      • Case

      Hapag-Lloyd AG: Complying with IMO 2020

      By: Benjamin C. Esty, Mette Fuglsang Hjortshoej and Emer Moloney
      A new environmental regulation known as IMO 2020 was creating what one industry analyst called “the biggest shakeup for the oil and shipping industries in decades.” According to the new regulation, all ocean-going ships would have to limit their sulfur emissions by... View Details
      Keywords: Valuation; Ship Transportation; Strategic Planning; Game Theory; Pollutants; Supply Chain; Corporate Accountability; Capital Budgeting; Environmental Sustainability; Governing Rules, Regulations, and Reforms; Governance Compliance; Shipping Industry; Transportation Industry; Germany
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      Esty, Benjamin C., Mette Fuglsang Hjortshoej, and Emer Moloney. "Hapag-Lloyd AG: Complying with IMO 2020." Harvard Business School Case 220-003, November 2019.
      • November 2019 (Revised June 2020)
      • Case

      Indigo Agriculture: Harnessing Nature

      By: Marco Iansiti, Michael W. Toffel and James Barnett
      Indigo Agriculture used a digital-enabled research and development (R&D) process to launch its initial product, microbial coatings for agricultural seeds, which increase crop yields while reducing the need for fertilizers. In doing so, the company developed direct... View Details
      Keywords: Carbon Sequestration; Operations; Supply Chain; Social Enterprise; Product Development; Distribution Channels; Business Strategy; Digital Platforms; Environmental Sustainability; Science-Based Business; Climate Change; Agriculture and Agribusiness Industry; Green Technology Industry; United States; Massachusetts
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      Iansiti, Marco, Michael W. Toffel, and James Barnett. "Indigo Agriculture: Harnessing Nature." Harvard Business School Case 620-024, November 2019. (Revised June 2020.)
      • November 2019 (Revised January 2020)
      • Case

      Bayer Crop Science

      By: David E. Bell, Damien McLoughlin, Natalie Kindred and James Barnett
      In mid-2019, a year after German conglomerate Bayer Group closed its acquisition of U.S.-based seeds giant Monsanto, the leadership of Bayer’s Crop Science division (which absorbed Monsanto) is reflecting on the opportunities ahead. Some observers have questioned... View Details
      Keywords: Agribusiness; Research and Development; Innovation and Invention; Innovation Strategy; Mergers and Acquisitions; Consolidation; Customer Value and Value Chain; Change Management; Agriculture and Agribusiness Industry; Technology Industry; United States; Germany
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      Bell, David E., Damien McLoughlin, Natalie Kindred, and James Barnett. "Bayer Crop Science." Harvard Business School Case 520-055, November 2019. (Revised January 2020.)
      • November 2019 (Revised April 2020)
      • Case

      Danone: Changing the Food System

      By: David E. Bell, Federica Gabrieli and Daniela Beyersdorfer
      Emmanuel Faber, Chairman and CEO of the food and beverage company Danone, believed that humankind had only ten years to bend the curve on climate change and restore the biodiversity that the global food and agricultural ecosystem was critically dependent on. Upon... View Details
      Keywords: Animal-Based Agribusiness; Plant-Based Agribusiness; Food; Nutrition; Quality; Business and Stakeholder Relations; Environmental Sustainability; Climate Change; Business Model; Food and Beverage Industry; Agriculture and Agribusiness Industry; France
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      Bell, David E., Federica Gabrieli, and Daniela Beyersdorfer. "Danone: Changing the Food System." Harvard Business School Case 520-053, November 2019. (Revised April 2020.)
      • November 9, 2019
      • Article

      Effect of Revealing Authors' Conflicts of Interests in Peer Review: Randomized Controlled Trial

      By: Leslie K. John, George Loewenstein, Andrew Marder and Michael Callaham
      Objective: To assess the impact of disclosing authors’ conflict of interest declarations to peer reviewers at a medical journal.
      Design: Randomised controlled trial.

      Setting: The study was conducted within the manuscript review process at the... View Details
      Keywords: Conflicts Of Interest; Peer Review; Randomized Controlled Trial; Scientific Publication; Conflict of Interests; Journals and Magazines; Science
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      John, Leslie K., George Loewenstein, Andrew Marder, and Michael Callaham. "Effect of Revealing Authors' Conflicts of Interests in Peer Review: Randomized Controlled Trial." BMJ: British Medical Journal 367, no. 8221 (November 9, 2019).
      • 2020
      • Working Paper

      How ESG Issues Become Financially Material to Corporations and Their Investors

      By: George Serafeim
      Management and disclosure of environmental, social and governance (ESG) issues have received substantial interest over the last decade. In this paper, we outline a framework of how ESG issues become financially material, affecting corporate profitability and valuation.... View Details
      Keywords: Materiality; ESG; Pharmaceutical Companies; Business Ethics; Sustainability; Environment; Disclosure; Disclosure And Access; Regulation; Social Impact; Environmental Sustainability; Social Issues; Corporate Governance; Ethics; Corporate Disclosure; Corporate Accountability; Resource Allocation; Finance; Accounting; Valuation
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      Freiberg, David, Jean Rogers, and George Serafeim. "How ESG Issues Become Financially Material to Corporations and Their Investors." Harvard Business School Working Paper, No. 20-056, November 2019. (Revised November 2020.)
      • November 2019 (Revised April 2020)
      • Technical Note

      The Life Sciences Revolution: A Technical Primer

      By: Gary P. Pisano, William J. Anderson, Amitabh Chandra, Clarissa Ceruti and Stephanie Oestreich
      For more than two decades, scientific advances have been driving profound changes in drug discovery and the drug industry itself. This case provides an overview and description of these technical and scientific advances. Written for the nonscientific reader, it may be... View Details
      Keywords: Science; Technological Innovation; Technology; Pharmaceutical Industry; Biotechnology Industry
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      Pisano, Gary P., William J. Anderson, Amitabh Chandra, Clarissa Ceruti, and Stephanie Oestreich. "The Life Sciences Revolution: A Technical Primer." Harvard Business School Technical Note 620-054, November 2019. (Revised April 2020.)
      • 2019
      • Working Paper

      Intelligent Design of Inclusive Growth Strategies

      By: Robert S. Kaplan, George Serafeim and Eduardo Tugendhat
      Improving corporate engagement with society, as advocated in the Business Roundtable’s 2019 statement, should not be viewed as a zero-sum proposition where attention to new stakeholders detracts from delivering shareholder value. Corporate programs for sustainable and... View Details
      Keywords: Inclusion; Sustainability; Performance Measures; Environmental Sustainability; Social Issues; Strategy; Governance; Corporate Social Responsibility and Impact; Business and Stakeholder Relations
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      Kaplan, Robert S., George Serafeim, and Eduardo Tugendhat. "Intelligent Design of Inclusive Growth Strategies." Harvard Business School Working Paper, No. 20-050, October 2019.
      • October 2019 (Revised December 2019)
      • Supplement

      Extend Fertility: Conceiving the Market for Egg Preservation (B)

      By: Debora L. Spar and Olivia Hull
      Keywords: Strategy; Information Technology; Business Startups; Entrepreneurship; Innovation Strategy; Technological Innovation; Commercialization; Science-Based Business; Marketing Strategy; Business Plan; Product Marketing; Product Launch; Product Positioning; Mission and Purpose; Personal Development and Career; Social Issues; Integration; Health; Health Industry
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      Spar, Debora L., and Olivia Hull. "Extend Fertility: Conceiving the Market for Egg Preservation (B)." Harvard Business School Supplement 720-017, October 2019. (Revised December 2019.)
      • 2021
      • Working Paper

      Shareholder Activism and Firms' Voluntary Disclosure of Climate Change Risks

      By: Caroline Flammer, Michael W. Toffel and Kala Viswanathan
      This paper examines whether—in the absence of mandated disclosure requirements—shareholder activism can elicit greater disclosure of firms’ exposure to climate change risks. We find that environmental shareholder activism increases the voluntary disclosure of climate... View Details
      Keywords: Shareholder Activism; Climate Risk; Corporate Accountability; Climate Change; Corporate Disclosure; Corporate Governance; Corporate Social Responsibility and Impact; Business and Shareholder Relations; Risk and Uncertainty; Natural Environment; Environmental Sustainability; Financial Services Industry; United States
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      Flammer, Caroline, Michael W. Toffel, and Kala Viswanathan. "Shareholder Activism and Firms' Voluntary Disclosure of Climate Change Risks." Harvard Business School Working Paper, No. 20-049, October 2019. (Revised March 2021.)
      • October 16, 2019
      • Article

      Where ESG Fails

      By: Michael E. Porter, George Serafeim and Mark Kramer
      We are entering a new stage of understanding of the linkage between investment performance and social impact. Previous approaches, such as socially responsible investing and environmental, social, and governance (ESG) screening, have obscured the opportunities for... View Details
      Keywords: ESG; Sustainability; Environment; Social Impact; Impact Investing; ESG (Environmental, Social, Governance) Performance; ESG Reporting; Shared Value; Environmental Sustainability; Social Issues; Investment; Value; Strategy
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      Porter, Michael E., George Serafeim, and Mark Kramer. "Where ESG Fails." Institutional Investor (October 16, 2019).
      • October 2019 (Revised February 2025)
      • Case

      A Conversation with Ellen J. Kullman, Chair & CEO of DuPont, 2009-2015

      By: Lynn S. Paine and Will Hurwitz
      Ellen J. Kullman, the retired Chairman and CEO of DuPont, describes how she guided the storied science and technology company through a contentious proxy battle with activist investor Trian Partners, which acquired DuPont shares in 2013 and sought to break up the... View Details
      Keywords: Agribusiness; Capital Structure; Corporate Accountability; Corporate Governance; Institutional Investing; Leadership; Leadership Style; Management; Transformation; Agriculture and Agribusiness Industry; Chemical Industry; United States
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      Paine, Lynn S., and Will Hurwitz. "A Conversation with Ellen J. Kullman, Chair & CEO of DuPont, 2009-2015." Harvard Business School Case 320-017, October 2019. (Revised February 2025.)
      • October 2019 (Revised November 2019)
      • Case

      C16 Biosciences: Lab-Grown Palm Oil

      By: Jeffrey J. Bussgang and Olivia Hull
      Synthetic biology start-up C16 Biosciences wants to solve a big problem: replace palm oil, a major contributor to deforestation and climate change, with a lab-grown substitute. CEO Shara Ticku has ambitious plans to supply her lab-grown palm oil to food manufacturers,... View Details
      Keywords: Science-Based Business; Environmental Sustainability; Social Entrepreneurship; Product Development; Product Positioning; Venture Capital; Strategy; Decision Making; Food and Beverage Industry; Consumer Products Industry
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      Bussgang, Jeffrey J., and Olivia Hull. "C16 Biosciences: Lab-Grown Palm Oil." Harvard Business School Case 820-008, October 2019. (Revised November 2019.)
      • September 2019
      • Case

      Funding Sources for Science & Technology Start-ups in India

      By: Tarun Khanna, Arjun Swarup and Rachna Tahilyani
      India's start-up ecosystem is amongst the largest globally, with a variety of funding options from angel investors, venture capital and corporate venture capital to debt. Classic consumer focused start-ups which look to leverage technology have been able to raise... View Details
      Keywords: Venture Capital; Business Startups; Science; Information Technology; Financial Services Industry; Banking Industry; Technology Industry; India; South Asia
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      Khanna, Tarun, Arjun Swarup, and Rachna Tahilyani. "Funding Sources for Science & Technology Start-ups in India." Harvard Business School Case 720-401, September 2019.
      • September 2019 (Revised August 2020)
      • Case

      Engineering an Inclusive Bioeconomy

      By: Tarun Khanna, Raffaella Sadun and Susie L. Ma
      In 2019, entrepreneur Juan Carlos Castilla-Rubio was developing a project he hoped could generate and share wealth from the natural resources of the Amazon without destroying those resources. His idea, called Earth Bank of Codes (EBC), would create a library of the... View Details
      Keywords: Decision Making; Development Economics; Entrepreneurship; Innovation and Invention; Intellectual Property; Emerging Markets; Market Design; Marketplace Matching; Science; Genetics; Natural Environment; Environmental Sustainability; Climate Change; Social Enterprise; Strategy; Strategic Planning; Information Technology; Ownership; Social Psychology; Trust; Society; Biotechnology Industry; South America; Amazon Basin
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      Khanna, Tarun, Raffaella Sadun, and Susie L. Ma. "Engineering an Inclusive Bioeconomy." Harvard Business School Case 720-356, September 2019. (Revised August 2020.)
      • 2019
      • Working Paper

      Decarbonization Factors

      By: Alex Cheema-Fox, Bridget LaPerla, George Serafeim, David Turkington and Hui (Stacie) Wang
      In the face of accelerating climate change, investors are making capital allocations seeking to decarbonize portfolios by reducing the carbon emissions of their holdings. To understand the performance of portfolio decarbonization strategies and investor behavior... View Details
      Keywords: ESG; Investment Management; Factor Investing; Investor Behavior; Climate Change; Environmental Sustainability; Investment; Management
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      Cheema-Fox, Alex, Bridget LaPerla, George Serafeim, David Turkington, and Hui (Stacie) Wang. "Decarbonization Factors." Harvard Business School Working Paper, No. 20-037, September 2019. (Revised November 2019.)
      • 2019
      • Article

      Sustaining Open Innovation Through a 'Center of Excellence'

      By: Elizabeth E. Richard, Jeffrey R. Davis, Jin Hyun Paik and Karim R. Lakhani
      This paper presents NASA’s experience using a Center of Excellence (CoE) to scale and sustain an open innovation program as an effective problem-solving tool and includes strategic management recommendations for other organizations based on lessons... View Details
      Keywords: Crowdsourcing; Culture Change; Open Innovation; Center Of Excellence; Collaborative Innovation and Invention; Organizational Culture; Change Management
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      Richard, Elizabeth E., Jeffrey R. Davis, Jin Hyun Paik, and Karim R. Lakhani. "Sustaining Open Innovation Through a 'Center of Excellence'." Strategy & Leadership 47, no. 3 (2019): 19–26.
      • Article

      Advancing Computational Biology and Bioinformatics Research Through Open Innovation Competitions

      By: Andrea Blasco, Michael G. Endres, Rinat A. Sergeev, Anup Jonchhe, Max Macaluso, Rajiv Narayan, Ted Natoli, Jin H. Paik, Bryan Briney, Chunlei Wu, Andrew I. Su, Aravind Subramanian and Karim R. Lakhani
      Open data science and algorithm development competitions offer a unique avenue for rapid discovery of better computational strategies. We highlight three examples in computational biology and bioinformatics research where the use of competitions has yielded significant... View Details
      Keywords: Computational Biology; Bioinformatics; Innovation Competitions; Research; Collaborative Innovation and Invention
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      Blasco, Andrea, Michael G. Endres, Rinat A. Sergeev, Anup Jonchhe, Max Macaluso, Rajiv Narayan, Ted Natoli, Jin H. Paik, Bryan Briney, Chunlei Wu, Andrew I. Su, Aravind Subramanian, and Karim R. Lakhani. "Advancing Computational Biology and Bioinformatics Research Through Open Innovation Competitions." PLoS ONE 14, no. 9 (September 2019).
      • Summer 2019
      • Article

      Breaking Even: Political Economy and Private Enterprise in the Norwegian Glass Industry, 1739-1803

      By: Rolv Petter Amdam, Robert Fredona and Sophus A. Reinert
      Using internal debates and surviving account books, this article traces the 18th-century history of the Norwegian glass industry, created to exploit Norway's immense natural resource wealth, and of the chartered company that would later become Norway's iconic... View Details
      Keywords: Glass Industry; Natural Resources; Profitability; Political Economy; Cameralism; Liberalization; Patriotism; Profit; Natural Environment; Business History; Norway
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      Amdam, Rolv Petter, Robert Fredona, and Sophus A. Reinert. "Breaking Even: Political Economy and Private Enterprise in the Norwegian Glass Industry, 1739-1803." Business History Review 93, no. 2 (Summer 2019): 275–317.
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