Publications

2024
Working Paper

Tamoxifen—Reducing Breast Cancer Risks: Case Histories of Transformational Advances

By: Amar Bhidé, Srikant Datar and Katherine Stebbins

We describe the development of tamoxifen, considered a “gold standard” treatment for millions of breast cancer patients. Specifically, we describe breast cancer treatments before tamoxifen’s development; the initial development of tamoxifen from 1960 to 1973;... View Details

Keywords: Health Care and Treatment; Technological Innovation; Innovation and Invention; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Governing Rules, Regulations, and Reforms

2024
Working Paper

Laparoscopy—Minimally Invasive Surgery: Case Histories of Transformational Advances

By: Amar Bhidé, Caitlin N. Bowler and Srikant M. Datar

We describe how operations through laparoscopes – tubular instruments inserted into abdominal cavities – revolutionized gynecological and other surgeries inside the abdomen, such as gall bladder removal. Specifically, we chronicle the 1) foundational contributions of... View Details

Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms

2024
Working Paper

Computed Tomography (CT)--Beyond Traditional X-Rays: Case Histories of Transformational Advances

By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins

This case history describes how Computed Tomography (CT) scanners - that combine Xrays and computers to image soft tissues of the brain and other organs -- have become a widely used diagnostic tool. Specifically, we chronicle the 1) initial development of CT... View Details

Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms

05 Oct 2009
Research & Ideas

The Vanguard Corporation

focused people on the long-term impact, so disposable products need to be more environmentally friendly. Again, it's not the words, it's the conversation. It's the actions of top leaders and the fact that they get successes out of View Details

Keywords: by Sean Silverthorne

05 Dec 2018
Blog Post

Leadership Fellow Henry Tsai: Working With City Leadership To Leverage Technology

was to work with HBS Community Partners, HBS alumni who conduct pro-bono consulting work, to develop a marketing strategy for San Jose’s innovation efforts. “If we can tell the View Details

December 2002 (Revised February 2003)
Case

Wyndham International: Fostering High-Touch with High-Tech

By: Lynda M. Applegate and Gabriele Piccoli

Examines a hotel chain's attempt to use information technology to achieve market dominance and build customer loyalty during a period of global industry decline. View Details

Keywords: Entrepreneurship; Competitive Strategy; Customer Focus and Relationships; Customer Satisfaction; Technological Innovation; Information Technology; Growth and Development Strategy; Business Strategy; Accommodations Industry

Educators

Web

Entrepreneurship in Life Sciences - Course Catalog

with the appropriate financial and human resources, and scaling. The course will explore which areas of the life sciences are ripe for innovation and entrepreneurship and will cover therapeutics, devices, diagnostics, and related service... View Details

January 2010 (Revised February 2011)
Case

The Random House Response to the Kindle

By: Bharat N. Anand and Peter Olson

In early 2010, e-readers, like Amazon's Kindle and Apple's impending iPad, threatened to disrupt the book publishing industry. The case provides an overview of the industry, describes the broader trends regarding e-readers, and asks: how should major publishers like... View Details

Keywords: Change Management; Trends; Disruptive Innovation; Technological Innovation; Consumer Behavior; Industry Structures; Corporate Strategy; Hardware; Publishing Industry

Educators

08 Oct 2015
Blog Post

Why We Recruit: DaVita Healthcare Partners, Inc.

Kelly Raulino, Manager, Redwoods Leadership Development, DaVita HealthCare Partners, Inc. Describe your organization in three to five sentences. DaVita HealthCare Partners, a Fortune 500® company, is one of the nation's largest and most View Details

Keywords: Health Care

09 Jan 2019
News

Why New England Needs New Ideas

In a recent piece in the Boston Globe Magazine, Professor Clay Christensen, Karen Dillon, a senior researcher at Christensen’s Institute for Disruptive Innovation, and Efosa Ojomo (MBA 2015), a research fellow at the Institute, use New England’s history of View Details

Keywords: New England

November 2010 (Revised April 2011)
Case

WiTricity: Electricity cuts the cord

By: William A. Sahlman and Evan Wade Richardson

Eric Giler, WiTricity CEO, must decide how to grow a company based around an untested but potentially ground-breaking technology for wireless electricity transmission. View Details

Keywords: Business Startups; Entrepreneurship; Technological Innovation; Growth and Development Strategy; Wireless Technology; Electronics Industry

Educators

01 Nov 2024
In Practice

Layoffs Surging in a Strong Economy? Advice for Navigating Uncertain Times

that their leaders have a realistic, rational, and focused path to the future. 2. How well are we treating the people who are being laid off? Intuit’s blog is worth reading for the care it demonstrates for the feelings and well-being of... View Details

Keywords: by Rachel Layne; Technology; Information Technology

Henry Wendt

In his term as CEO of the pharmaceutical giant, Wendt focused on a “3 point strategy” to help strengthen the business. His strategy consisted of increasing support of SmithKline’s best products, such as... View Details

Keywords: Healthcare

03 Oct 2006
First Look

First Look: October 3, 2006

a genocide that had claimed the lives of over 10 percent of its population. The case focuses on the formulation of an economic strategy to rebuild the economy and its institutions after the devastation.... View Details

Keywords: Sean Silverthorne

February 2018
Teaching Plan

Tesla in 2015

By: Lynda M. Applegate, Olivia Hull and Sarah Mehta

Teaching Note for HBS No. 817-081. View Details