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  • March 2014
  • Module Note

Implementing Environmentally Sustainable Operations

By: Michael W. Toffel
Keywords: Sustainability; Sustainability Management; Sustainability Reporting; Sustainable Supply Chains; Sustainable Operations; Environment; Environmental And Social Sustainability; Environmental Management; Environmental Operations; Environmental Performance; Environmental Policy; Environmental Protection; Environmental Strategy; Environmental Regulation; Operations Management; Operations Strategy; Supply Chain Management; Operations; Supply Chain; Business Processes; Corporate Social Responsibility and Impact; Performance Evaluation; Performance Improvement; Safety; Social Enterprise; Quality; Production; Working Conditions; Animal-Based Agribusiness; Buildings and Facilities; Agriculture and Agribusiness Industry; Apparel and Accessories Industry; Biotechnology Industry; Construction Industry; Manufacturing Industry
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Toffel, Michael W. "Implementing Environmentally Sustainable Operations." Harvard Business School Module Note 613-090, March 2014.
  • 20 Mar 2012
  • First Look

First Look: March 20

Market Governments—Qualitative Evidence from a Biotechnology Multinational Authors:Prithwiraj Choudhury, James Geraghty, and Tarun Khanna Publication:Global Strategy Journal 2, no. 1 (February 2012) Abstract We build on the emerging... View Details
Keywords: Sean Silverthorne
  • 23 Jun 2003
  • Research & Ideas

Historically Speaking: A Roundtable at HBS

Pharmaceutical Industries, to be published by The Free Press in 2004]. It includes a chapter on biotechnology, the next industry that will create a sea change in our lives. Spar: And biotechnology will go through the same pattern of... View Details
Keywords: by Jim Aisner
  • 06 Feb 2007
  • First Look

First Look: February 6, 2007

India, and asks if the world's leading biotechnology firm should develop similar delivery-based systems. Purchase this case: http://www.hbsp.harvard.edu/b01/en/common/item_detail.jhtml?id=507018 RKS Guitars Harvard Business School Case... View Details
Keywords: Martha Lagace
  • January 2017 (Revised March 2017)
  • Case

Royal DSM: From Continuous Transformation to Organic Growth

By: William W. George, Carin-Isabel Knoop and Amram Migdal
Royal DSM CEO Feike Sijbesma was pondering the challenges of shifting DSM’s global organization from the constant transformations of the past 100 years to creating organic growth. When Sijbesma took the helm as CEO in 2007, he further pushed and completed the company’s... View Details
Keywords: Organic Growth; Organizational Change; M&A; Mergers And Acquisitions; Divestment; Business Ventures; Business Divisions; Business Growth and Maturation; Restructuring; Change; Change Management; Transformation; Transition; Engineering; Chemicals; Mining; Ethics; Values and Beliefs; Finance; Capital Markets; Financial Markets; Food; Globalization; Global Strategy; Globalized Firms and Management; Globalized Markets and Industries; Health; Nutrition; History; Leadership; Leadership Development; Leadership Style; Leading Change; Management; Business or Company Management; Growth and Development Strategy; Growth Management; Management Practices and Processes; Management Style; Organizations; Corporate Social Responsibility and Impact; Mission and Purpose; Organizational Change and Adaptation; Organizational Culture; Organizational Design; Ownership; Public Ownership; Performance; Strategy; Adaptation; Consolidation; Corporate Strategy; Value; Value Creation; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry; Europe; Netherlands
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George, William W., Carin-Isabel Knoop, and Amram Migdal. "Royal DSM: From Continuous Transformation to Organic Growth." Harvard Business School Case 317-063, January 2017. (Revised March 2017.)
  • February 2024 (Revised March 2024)
  • Teaching Note

X: The Foghorn Decision

By: Kyle Myers and Walter Frick
Teaching Note for HBS Case No. 618-060. View Details
Keywords: Alternative Energy; Energy Generation; Energy Sources; Climate Change; Green Technology; Selection and Staffing; Knowledge; Product Design; Product Development; Research and Development; Risk and Uncertainty; Science-Based Business; Innovation and Invention; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry
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Myers, Kyle, and Walter Frick. "X: The Foghorn Decision." Harvard Business School Teaching Note 624-065, February 2024. (Revised March 2024.)
  • 19 May 2009
  • First Look

First Look: May 19, 2009

the significance levels are lower.   Cases & Course MaterialsAdnexus Therapeutics, Inc.: Considering the Exit Harvard Business School Case 609-015 Dr. John Mendlein, CEO of Adnexus Therapeutics Inc. (Adnexus), a private biotechnology... View Details
Keywords: Martha Lagace
  • 12 May 2009
  • First Look

First Look: May 12, 2009

Case 809-026 An executive from pharmaceutical company GSK must choose how much to integrate a recently acquired biotechnology firm, Sirtris. Moncef Slaoui, GSK's global head of R&D, championed the acquisition of Sirtris to gain access... View Details
Keywords: Martha Lagace
  • May 2025 (Revised June 2025)
  • Supplement

Michael Ku and Global Clinical Supply at Pfizer Inc.: Bringing Hope to Patients (D)

By: Linda A. Hill and Lydia Begag
This fourth installment in the Pfizer Global Clinical Supply (GCS) transformation case series highlights how over a decade of cultural and digital evolution positioned GCS to meet unprecedented global challenges. In 2011, Michael Ku became the Vice President of GCS and... View Details
Keywords: Innovation Leadership; Technological Innovation; Leadership Development; Leadership Style; Research and Development; Science-Based Business; Transformation; Health Pandemics; AI and Machine Learning; Analytics and Data Science; Digital Transformation; Leading Change; Product Launch; Supply Chain; Organizational Change and Adaptation; Alignment; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry; United States; Asia; Europe; Latin America
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Hill, Linda A., and Lydia Begag. "Michael Ku and Global Clinical Supply at Pfizer Inc.: Bringing Hope to Patients (D)." Harvard Business School Supplement 425-079, May 2025. (Revised June 2025.)
  • 2001
  • Other Unpublished Work

Clusters of Innovation Initiative: San Diego

By: Michael E. Porter
The study contains a conceptual framework for assessing the competitiveness of regional economies, an analysis of the San Diego region overall, as well as detailed assessments of two representative clusters—biotechnology/pharmaceuticals and communications. The report... View Details
Keywords: Clusters; Economics; Industry Clusters; Economy; Growth and Development; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry; San Diego
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Porter, Michael E. "Clusters of Innovation Initiative: San Diego." Council on Competitiveness, Washington, DC, May 2001. (Report.)
  • October 2012
  • Supplement

Aqua Bounty Courseware

By: Lucy White and Steve Burn-Murdoch
Valuation of a pre-revenue biotech company at IPO using probability trees and real option techniques. Company is based in Massachusetts and lists in London on AIM. Products are genetically-modified fast-growing salmon for fish farmers and disease-prevention drugs and... View Details
Keywords: IPO; Valuation; Real Options; Decision Tree; Biotech; Genetically Modified; Salmon; Entrepreneurship; Finance; Biotechnology Industry; Biotechnology Industry; North and Central America; Europe; South America
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White, Lucy, and Steve Burn-Murdoch. "Aqua Bounty Courseware." Harvard Business School Spreadsheet Supplement 213-701, October 2012.
  • December 2003 (Revised April 2004)
  • Case

Dragon's Teeth Vineyards

By: Alan D. MacCormack, Marius Leibold, Sven Voelpel and Kerry Herman
Dragon's Teeth Vineyards (DTV) is a South African wine producer that is considering whether to use genetically modified organisms (GMOs) in its wine-making process. GMOs promise to lower the costs of wine production significantly through increased yields and reduced... View Details
Keywords: Technological Innovation; Growth and Development Strategy; Genetics; Transition; Brands and Branding; Product Development; Product Design; Organizational Change and Adaptation; Technology Adoption; Biotechnology Industry; Biotechnology Industry; South Africa
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MacCormack, Alan D., Marius Leibold, Sven Voelpel, and Kerry Herman. "Dragon's Teeth Vineyards." Harvard Business School Case 604-069, December 2003. (Revised April 2004.)
  • February 1999
  • Teaching Note

Pioneer Hi-Bred International, Inc.: Supply Management TN

By: Francis Aguilar, Paul Clark and Xin Xi He
Teaching Note for (9-898-238) and (9-898-239). View Details
Keywords: Biotechnology Industry; Biotechnology Industry
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Aguilar, Francis, Paul Clark, and Xin Xi He. "Pioneer Hi-Bred International, Inc.: Supply Management TN." Harvard Business School Teaching Note 899-208, February 1999.
  • 13 Jun 2005
  • Research & Ideas

From Turf Wars to Learning Curves: How Hospitals Adopt New Technology

in many cases, perform identical procedures in two or more hospitals during the course of a given week. We have found that this movement has negative effects on the degree to which surgeons are able to leverage their prior experience to improve future performance. We... View Details
Keywords: by Sara Grant; Health
  • October 2020 (Revised April 2022)
  • Case

When Institutions Fail: HIV/AIDS in the 1980s

By: Tom Nicholas and Christian Godwin
During the early 1980s, young gay men in urban centers such as San Francisco and New York City began contracting a mysterious illness that would come to be known as HIV/AIDS. A diagnosis meant almost certain death, with a less than 1% survival rate. Conflicting... View Details
Keywords: Ethics; Policy; Government and Politics; Health Pandemics; History; Rights; Media; Organizations; Business and Community Relations; Religion; Social Psychology; Identity; Prejudice and Bias; Social Issues; Public Opinion; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry; United States
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Nicholas, Tom, and Christian Godwin. "When Institutions Fail: HIV/AIDS in the 1980s." Harvard Business School Case 821-002, October 2020. (Revised April 2022.)
  • January 2016 (Revised February 2016)
  • Course Overview Note

The Sustainable Core: Operations Management

By: Michael W. Toffel and L. Beril Toktay
This note is designed to help faculty embed environmental sustainability content into their core Operations Management course at the MBA or undergraduate level. It can also be used to identify cases with environmental content that can be used in operations electives... View Details
Keywords: Environmental Management; Operations Management; Sustainable Operations; Environmental Regulation; Operations; Supply Chain; Supply Chain Management; Agriculture and Agribusiness Industry; Biotechnology Industry; Food and Beverage Industry; Construction Industry; Forest Products Industry; Retail Industry
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Toffel, Michael W., and L. Beril Toktay. "The Sustainable Core: Operations Management." Harvard Business School Course Overview Note 616-022, January 2016. (Revised February 2016.)
  • 02 Feb 2016
  • First Look

February 2, 2016

agent-based simulation model of network emergence. Using data on technology partnerships from 1983 to 1999 among firms in the automotive, biotechnology and pharmaceuticals, chemicals, microelectronics, new materials, and... View Details
Keywords: Sean Silverthorne
  • 11 Nov 2015
  • Working Paper Summaries

Public R&D Investments and Private-sector Patenting: Evidence from NIH Funding Rules

Keywords: by Danielle Li; Biotechnology; Biotechnology; Biotechnology; Biotechnology
  • 24 Sep 2007
  • Research & Ideas

The FDA: What Will the Next 100 Years Bring?

The U.S. Food and Drug Administration, which was created by the passage of the 1906 Federal Food and Drugs Act, regulates companies and industries accounting for one-quarter of all consumer spending, roughly $1.5 trillion worth of consumer goods and medicines. It... View Details
Keywords: by Sean Silverthorne; Biotechnology; Biotechnology; Biotechnology; Biotechnology
  • 21 Apr 2009
  • First Look

First Look: April 21, 2009

this case: http://harvardbusinessonline.hbsp.harvard.edu/b01/en/common/item_detail.jhtml?id=807106 Note on Biotech Business Development Harvard Business School Note 807-032 Describes the business development process in biotechnology... View Details
Keywords: Martha Lagace
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