Publications

October 2009 (Revised July 2013)
Case

Gilead Sciences, Inc.: Access Program

By: V. Kasturi Rangan and Katharine Lee

Gilead Sciences, the U.S. leader in HIV/AIDS medicines, with global sales of $5.4 billion in 2009, had undertaken several innovative actions to make its anti-viral products available to over 100 low- and middle-income countries. Having reached nearly 680,000 patients... View Details

Keywords: Health Care and Treatment; Emerging Markets; Product; Sales; Competitive Strategy; Biotechnology Industry; Biotechnology Industry

June 2008
Case

Gordon Williams: Clinical Research at Brigham and Women's Hospital

By: H. Kent Bowen and Courtney Purrington

Clinical research is a critical element of biomedical research and development. This case describes the challenges of clinical research, and its role in bringing breakthroughs to patients. Dr. Williams leads through his own research and special programs to train... View Details

Keywords: Training; Health Care and Treatment; Success; Programs; Research and Development; Biotechnology Industry; Biotechnology Industry

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June 2003 (Revised October 2004)
Case

Novartis: The Challenge of Success (D)

By: Sandra J. Sucher and Stacy McManus

Supplements the (A) and (B) cases. View Details

Keywords: Biotechnology Industry; Biotechnology Industry

11 May 2010
First Look

First Look: May 11

Amyris Biotechnologies: Commercializing Biofuel Gary P. Pisano and Alison Berkley WagonfeldHarvard Business School Case 610-031 In 2009, Amyris Biotechnologies was building a plant in Brazil that used synthetic biology to convert... View Details

Keywords: Martha Lagace

09 Apr 2012
Research & Ideas

Who Sways the USDA on GMO Approvals?

Many corporations have gotten good at pulling the levers of government to tilt the odds in their favor, weakening regulations or securing perks, justified or not, to further their business interests. Economists use the term "regulatory capture" to describe... View Details

Keywords: by Michael Blanding; Biotechnology; Biotechnology; Biotechnology

September 2013 (Revised August 2014)
Case

Claritas Genomics

By: Robert F. Higgins and Matthew Preble

Claritas Genomics was formed in January 2013 when BCH spun out its Genetics Diagnostic Lab into a fully commercial entity. Claritas offered over 100 genomic tests to detect a range of conditions, including autism and intellectual disabilities, and was developing new... View Details

September 2008
Background Note

Background on the Technology of Molecular Diagnostics

By: Regina E. Herzlinger and Jason Sanders

To be used as background reading for the "EXACT Sciences Corp.: Commercializing a Diagnostic Test" and "Diagnostic Genomics" cases, HBS nos. 308-090 and 309-040. View Details

Keywords: Health Testing and Trials; Technology; Biotechnology Industry; Biotechnology Industry

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September 2012 (Revised September 2012)
Course Overview Note

Building Life Science Businesses Fall 2012: Course Outline and Syllabus

By: Richard G. Hamermesh and Richard G. Hamermesh

This Course Outline and Syllabus gives an overview of the Fall 2012 class Building Life Science Businesses View Details

Keywords: Healthcare Ventures; Entrepreneurial Management; Entrepreneurship; Entrepreneurs; Health Care and Treatment; Health Testing and Trials; Medical Specialties; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry; Asia; North America; Europe

September 1989 (Revised December 1989)
Case

Beef Hormone Trade Dispute

By: Ray A. Goldberg

Keywords: Trade; Agribusiness; Food; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry

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11 Sep 2007
First Look

First Look: September 11, 2007

and deliverables. Many critical business challenges are detailed in this case. Nevertheless, given their fully integrated business model and significant manufacturing base, the odds are in Biocon's favor to overcome these challenges and lead India's View Details

Keywords: Martha Lagace

07 Jul 2003
Research & Ideas

The Organizational Model for Open Source

The more fundamental question that firms and policy makers need to be thinking about is just what type of good is software?—Siobhán O'Mahony Similar issues surface in the biotechnology world, where university and market conceptions of the... View Details

Keywords: by Mallory Stark

12 Oct 1999
Research & Ideas

Porter’s Perspective: Competing in the Global Economy

therefore, become unique local centers of innovation for the likes of mutual funds, venture capital, and biotechnology in Greater Boston or aircraft equipment and design, boat and shipbuilding, and metal fabrication in Seattle. The list... View Details

Keywords: Re: Michael E. Porter

17 Oct 2012
Research & Ideas

America Needs a Manufacturing Renaissance

innovation process, but it is not the whole thing. Innovation is about moving the idea from concept to the customer's hands. For some highly complex products (flat-panel displays, PV cells, and biotechnology drugs, to name a few) the... View Details

Keywords: by Gary P. Pisano & Willy C. Shih; Manufacturing

05 Aug 2014
First Look

First Look: August 5

Case 614-063 Merrimack Pharmaceuticals, Inc. (A) In 2006, Merrimack Pharmaceuticals was a fast-growing biotechnology company. Its leadership team was divided over whether to keep R&D organized in functional departments or transition... View Details

Keywords: Sean Silverthorne

January 2017 (Revised March 2017)
Case

Royal DSM: From Continuous Transformation to Organic Growth

By: William W. George, Carin-Isabel Knoop and Amram Migdal

Royal DSM CEO Feike Sijbesma was pondering the challenges of shifting DSM’s global organization from the constant transformations of the past 100 years to creating organic growth. When Sijbesma took the helm as CEO in 2007, he further pushed and completed the company’s... View Details

Keywords: Organic Growth; Organizational Change; M＆A; Mergers And Acquisitions; Divestment; Business Ventures; Business Divisions; Business Growth and Maturation; Restructuring; Change; Change Management; Transformation; Transition; Engineering; Chemicals; Mining; Ethics; Values and Beliefs; Finance; Capital Markets; Financial Markets; Food; Globalization; Global Strategy; Globalized Firms and Management; Globalized Markets and Industries; Health; Nutrition; History; Leadership; Leadership Development; Leadership Style; Leading Change; Management; Business or Company Management; Growth and Development Strategy; Growth Management; Management Practices and Processes; Management Style; Organizations; Corporate Social Responsibility and Impact; Mission and Purpose; Organizational Change and Adaptation; Organizational Culture; Organizational Design; Ownership; Public Ownership; Performance; Strategy; Adaptation; Consolidation; Corporate Strategy; Value; Value Creation; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry; Europe; Netherlands