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  • All HBS Web  (3,913)
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  • September 2018 (Revised December 2019)
  • Case

Zebra Medical Vision

By: Shane Greenstein and Sarah Gulick
An Israeli startup founded in 2014, Zebra Medical Vision developed algorithms that produced diagnoses from X-rays, mammograms, and CT-scans. The algorithms used deep learning and digitized radiology scans to create software that could assist doctors in making... View Details
Keywords: Radiology; Machine Learning; X-ray; CT Scan; Medical Technology; Probability; FDA 510(k); Diagnosis; Business Startups; Health Care and Treatment; Information Technology; Applications and Software; Competitive Strategy; Product Development; Commercialization; Decision Choices and Conditions; Health Industry; Medical Devices and Supplies Industry; Technology Industry; Israel
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Greenstein, Shane, and Sarah Gulick. "Zebra Medical Vision." Harvard Business School Case 619-014, September 2018. (Revised December 2019.)
  • December 2012 (Revised October 2022)
  • Case

Plastiq

By: Jeffrey J. Bussgang, Gaurav Jain, Liroy Haddad, Luke Langford and Matt Noble
The young CEO of a venture-backed startup needs to figure out his go to market strategy and the right profile for his first key sales hires. Should he develop partnerships with channels that would provide leverage or build out a direct sales force? And should the sales... View Details
Keywords: Payments; Sales; Channels; Credit Cards; Digital Platforms; Selection and Staffing; Cost vs Benefits; Salesforce Management; Marketing Channels; Business Startups; Business Strategy; Marketing Strategy; Partners and Partnerships; Management Systems
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Bussgang, Jeffrey J., Gaurav Jain, Liroy Haddad, Luke Langford, and Matt Noble. "Plastiq." Harvard Business School Case 813-125, December 2012. (Revised October 2022.)
  • May 2018 (Revised January 2019)
  • Case

AirFox (A): Embracing the Blockchain and an ICO

By: Jeffrey J. Bussgang, Edward B. Berk and Nate Schwalb
In summer 2017, Victor Santos, CEO of AirFox, considered whether to pivot his startup towards a new product built with blockchain—a quickly growing technology at the time. AirFox was an early stage startup that sold Software-as-a-Service (SaaS) to small telecom... View Details
Keywords: Blockchain; Cryptocurrency; Initial Coin Offering; ICO; Business Startups; Finance; Currency; Strategy; Decision Making; United States
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Bussgang, Jeffrey J., Edward B. Berk, and Nate Schwalb. "AirFox (A): Embracing the Blockchain and an ICO." Harvard Business School Case 818-097, May 2018. (Revised January 2019.)
  • Article

The Upside to Large Competitors

By: Neeru Paharia, Anat Keinan and Jill Avery
Large companies are often viewed as a major threat for startups and small companies; big companies have more financial resources and greater scale, market power, and brand awareness than small ones. However, our research finds that a smaller brand can actually benefit... View Details
Keywords: Brand Management; Competition; Marketing; Brands and Branding; Marketing Strategy; Consumer Products Industry; Food and Beverage Industry; Retail Industry; United States
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Paharia, Neeru, Anat Keinan, and Jill Avery. "The Upside to Large Competitors." MIT Sloan Management Review 56, no. 1 (Fall 2014).
  • December 2022 (Revised September 2024)
  • Case

Sword Health

By: Regina E. Herzlinger, Annelena Lobb and Carin-Isabel Knoop
Virgilio “V” Bento, CEO of Sword Health—a startup that provided virtual physical therapy to patients in self-insured firms via AI and sensor technology with supervision by a physical therapist with a doctorate—considered how to increase its U.S. market share. To do so,... View Details
Keywords: Business Growth and Maturation; Competitive Strategy; Health Industry; Technology Industry
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Herzlinger, Regina E., Annelena Lobb, and Carin-Isabel Knoop. "Sword Health." Harvard Business School Case 323-022, December 2022. (Revised September 2024.)
  • December 2018 (Revised April 2020)
  • Case

Fluidity: The Tokenization of Real Estate Assets

By: Marco Di Maggio, David Lane and Susie Ma
In December 2018, the blockchain startup Fluidity was about to participate in its first tokenization deal, which would create digital access to property rights in a 12-unit Manhattan condominium complex. The deal was proof-of-concept for Fluidity, which hoped to... View Details
Keywords: Blockchain; Tokenization; Data Security; Revenue Model; Finance; Technological Innovation; Strategy
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Di Maggio, Marco, David Lane, and Susie Ma. "Fluidity: The Tokenization of Real Estate Assets." Harvard Business School Case 219-057, December 2018. (Revised April 2020.)
  • 12 May 2017
  • Working Paper Summaries

Equality and Equity in Compensation

Keywords: by Jiayi Bao and Andy Wu
  • July–August 2016
  • Article

The Decoupling Effect of Digital Disruptors

By: Thales S. Teixeira and Peter Jamieson
A new wave of Internet startups is disrupting established businesses by the process of “decoupling.” In this article, the authors discuss how these new digital disruptors allow consumers to benefit from one activity (e.g., watching shows) without incurring the cost of... View Details
Keywords: Competition; Internet and the Web; Business Startups; Product Marketing; Customization and Personalization
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Teixeira, Thales S., and Peter Jamieson. "The Decoupling Effect of Digital Disruptors." European Business Review (July–August 2016): 17–24.
  • 11 Jan 2022
  • Cold Call Podcast

Can Entrepreneurs and Governments Team Up to Solve Big Problems?

Keywords: Re: Mitchell B. Weiss; Technology
  • 11 May 2016
  • Cold Call Podcast

Who Owns Space?

Keywords: Re: Matthew C. Weinzierl
  • March 2021
  • Supplement

CashDrop (B1)

By: Rembrand Koning, Paul A. Gompers and Sarah Gulick
After the events in CashDrop A, Flores-Martinez received two concrete offers from VC funds for his startup business, CashDrop. This case describes the tensions between the two funds: a traditional VC fund who would offer Flores-Martinez a prestigious platform, and a... View Details
Keywords: Small Business; Entrepreneurship; Business Startups; Venture Capital; Internet and the Web; Decision Choices and Conditions; Technology Industry; Financial Services Industry; Chicago; Illinois
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Koning, Rembrand, Paul A. Gompers, and Sarah Gulick. "CashDrop (B1)." Harvard Business School Supplement 221-052, March 2021.
  • 11 May 2017
  • Working Paper Summaries

Coordination Frictions in Venture Capital Syndicates

Keywords: by Ramana Nanda and Matthew Rhodes-Kropf; Banking
  • Research Summary

Competing business models

By: Ramon Casadesus-Masanell
Building on the literatures on competitive positioning and the theory of industrial organization, my work seeks to tackle previously unaddressed questions by studying situations where firms compete in dissimilar ways. Some examples of these questions include:View Details
  • October 1981 (Revised June 1982)
  • Case

Concept Devices, Inc.: International Market Entry

Concept is a highly touted startup venture in distributed data processing computers. The company has only made one sale to date, but has an order backlog for its unique product and expects an almost vertical growth curve. The company has been courted seriously by... View Details
Keywords: Global Strategy; Business Startups; Computer Industry; France; United Kingdom
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Bonoma, Thomas V. "Concept Devices, Inc.: International Market Entry." Harvard Business School Case 582-052, October 1981. (Revised June 1982.)
  • November 2018 (Revised June 2022)
  • Teaching Note

AirFox (A): Embracing the Blockchain and an ICO

By: Jeffrey J. Bussgang and Nathaniel Schwalb
Teaching Note for HBS No. 818-097. In summer 2017, Victor Santos, CEO of AirFox, considered whether to pivot his startup towards a new product built with blockchain—a quickly growing technology at the time. AirFox was an early stage startup that sold... View Details
Keywords: Blockchain; Cryptocurrency; Initial Coin Offering; ICO; Business Startups; Finance; Currency; Strategy; Decision Making; United States
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Bussgang, Jeffrey J., and Nathaniel Schwalb. "AirFox (A): Embracing the Blockchain and an ICO." Harvard Business School Teaching Note 819-065, November 2018. (Revised June 2022.)
  • July–August 2025
  • Article

How to Identify the Perfect Cofounder

By: Julia Austin
One of the first and most important decisions entrepreneurs make is whether to go it alone or bring on cofounders. Many investors favor startups with multiple founders, believing that a team reduces business risk by diversifying skills, sharing responsibilities, and... View Details
Keywords: Entrepreneurship; Business Startups; Partners and Partnerships; Experience and Expertise
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Austin, Julia. "How to Identify the Perfect Cofounder." Harvard Business Review 103, no. 4 (July–August 2025): 108–117.
  • July 2021
  • Case

Y Combinator

By: John R. Wells
Y Combinator (YC) was a business startup accelerator based in Mountain View, California. Originally founded in Cambridge, Massachusetts, in 2005, by 2021, YC listed 2,830 companies amongst its alumni. More than 80% of these companies were still active, had been... View Details
Keywords: Venture Capital; Growth and Development; Business Startups; Decisions; Strategy
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Wells, John R. "Y Combinator." Harvard Business School Case 721-498, July 2021.
  • June 2019
  • Technical Note

Valuing Employee Equity at Early Stage Ventures

By: Shikhar Ghosh, Christopher Stanton and Sanchali Pal
The note introduces a framework to consider factors that influence the value of employee equity at early stage ventures. Valuing equity is complex, and it important to account for expected dilution, assess exit potential, and acknowledge the high rate of failure in... View Details
Keywords: Employees; Equity; Valuation; Business Startups
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Ghosh, Shikhar, Christopher Stanton, and Sanchali Pal. "Valuing Employee Equity at Early Stage Ventures." Harvard Business School Technical Note 819-167, June 2019.
  • September 2004
  • Case

Valhalla Partners Due Diligence

By: William A. Sahlman and Dan Heath
The Valhalla Partners venture capitial firm introduced a new approach to the due-diligence process. An internal due-diligence report analyzes Telco Exchange, a startup company in the IT software space. An extended excerpt examines the trade-offs involved in the new... View Details
Keywords: Communication Technology; Risk Management; Venture Capital; Business Plan; Corporate Entrepreneurship; Investment; Mobile and Wireless Technology; Corporate Finance; Financial Services Industry; Telecommunications Industry
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Sahlman, William A., and Dan Heath. "Valhalla Partners Due Diligence." Harvard Business School Case 805-033, September 2004.
  • May 2017 (Revised November 2017)
  • Case

Cotopaxi: Managing Growth for Good

By: Andy Wu and Laura Huang
Cotopaxi, an innovative outdoor gear business targeting millennials, focuses on profit and social impact. This registered benefit corporation was formed by Davis Smith who coalesced his experiences as a Wharton MBA student along with professional knowledge from an... View Details
Keywords: Entrepreneurship; Social Venture; Benefit Corporation; B-Corp; Retail; Consumer Products; Apparel; Social Impact; Social Entrepreneurship; Business Model; Product Positioning; Social Enterprise; Mission and Purpose; Consumer Products Industry; Retail Industry
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Wu, Andy, and Laura Huang. "Cotopaxi: Managing Growth for Good." Harvard Business School Case 717-488, May 2017. (Revised November 2017.)
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