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      • March 2022
      • Article

      Winner Takes All? Tech Clusters, Population Centers, and the Spatial Transformation of U.S. Invention

      By: Brad Chattergoon and William R. Kerr
      U.S. invention has become increasingly concentrated around major tech centers since the 1970s, with implications for how much cities across the country share in concomitant local benefits. Is invention becoming a winner-takes-all race? We explore the rising spatial... View Details
      Keywords: Clusters; Invention; Agglomeration; Artificial Intelligence; Innovation and Invention; Patents; Applications and Software; Industry Clusters; AI and Machine Learning
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      Chattergoon, Brad, and William R. Kerr. "Winner Takes All? Tech Clusters, Population Centers, and the Spatial Transformation of U.S. Invention." Art. 104418. Research Policy 51, no. 2 (March 2022).
      • February 23, 2022
      • Article

      Can WEB3 Bring Back Competition to Digital Platforms?

      By: Christian Catalini and Scott Duke Kominers
      Like the early Internet, blockchain and Web3 applications promise a new wave of decentralization and competition—yet at the same time, it is unclear which of the dynamics that drove concentration in online platforms and services will remain in force under the Web3... View Details
      Keywords: Web3; Blockchain; Interoperability; Internet and the Web; Technological Innovation; Competition; Digital Platforms
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      Catalini, Christian, and Scott Duke Kominers. "Can WEB3 Bring Back Competition to Digital Platforms?" Competition Policy International (online) (February 23, 2022).
      • February 2022
      • Case

      Cleveland Clinic Abu Dhabi

      By: Linda A. Hill and Emily Tedards
      In 2006, the Cleveland Clinic and Mubadala Investment Company partnered with a bold ambition to deliver world class healthcare in the United Arab Emirates. In 2015, after nearly a decade of planning and construction, Cleveland Clinic Abu Dhabi opened its doors. By... View Details
      Keywords: Organizational Behavior; Culture; Alignment; Organizational Effectiveness; Purpose; Impact; Leadership Development; Diversity; Collaboration; Co-creation; Learning Organizations; Empowerment; Teams; Team Dynamics; Teamwork; Team Effectiveness; Trust; Talent; Talent Development And Retention; Psychological Safety; Organizational Evolution; Coaching; Board; Analytics; Innovation; Data; Data Visualization; Digital Technology; Digital; Customer Experience; Experimentation; Change Management; Data-driven Decision-making; Debates; Ecosystem; Partnership; Telemedicine; Sustainability; Global Organizations; Local; Hospital; Healthcare; United Arab Emirates; Health Care and Treatment; Partners and Partnerships; Globalization; Quality; Organizational Culture; Mission and Purpose; Innovation and Management; Information Technology; Joint Ventures; Leadership; Performance Effectiveness; Abu Dhabi; United Arab Emirates
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      Hill, Linda A., and Emily Tedards. "Cleveland Clinic Abu Dhabi." Harvard Business School Case 422-058, February 2022.
      • February 2022
      • Case

      Cleveland Clinic Abu Dhabi (Abridged)

      By: Linda A. Hill and Emily Tedards
      In 2006, the Cleveland Clinic and Mubadala Investment Company partnered with a bold ambition to deliver world class healthcare in the United Arab Emirates. In 2015, after nearly a decade of planning and construction, Cleveland Clinic Abu Dhabi opened its doors. By... View Details
      Keywords: Organization Behavior; Culture; Alignment; Organizational Effectiveness; Purpose; Impact; Leadership Development; Diversity; Collaboration; Co-creation; Learning Organizations; Empowerment; Teams; Team Dynamics; Teamwork; Team Effectiveness; Trust; Talent; Talent Development And Retention; Psychological Safety; Organizational Evolution; Coaching; Board; Analytics; Innovation; Data; Data Visualization; Digital Technology; Digital; Customer Experience; Experimentation; Change Management; Data-driven Decision-making; Debates; Ecosystem; Partnership; Telemedicine; Sustainability; Global Organizations; Local; Hospital; Healthcare; United Arab Emirates; Health Care and Treatment; Partners and Partnerships; Globalization; Quality; Organizational Culture; Mission and Purpose; Innovation and Management; Information Technology; Joint Ventures; Leadership; Performance Effectiveness; Abu Dhabi; United Arab Emirates
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      Hill, Linda A., and Emily Tedards. "Cleveland Clinic Abu Dhabi (Abridged)." Harvard Business School Case 422-056, February 2022.
      • February 2022
      • Case

      Leading The UK Vaccine Task Force

      By: Amy C. Edmondson and Claudia Pienica
      This case describes the first six months of the UK Vaccine Taskforce, under the leadership of Kate Bingham. With a career spent in the private sector as a biotech investor, Bingham’s appointment within the government was considered unusual. The overarching brief given... View Details
      Keywords: COVID-19; Vaccine; Government; Health Pandemics; Health Care and Treatment; Science; Innovation and Invention; Groups and Teams; Leadership; Decision Making; Government and Politics; Health; Innovation and Management; Governance; Change; Government Administration; Health Industry; Financial Services Industry; Public Administration Industry; Europe; United Kingdom
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      Edmondson, Amy C., and Claudia Pienica. "Leading The UK Vaccine Task Force." Harvard Business School Case 622-079, February 2022.
      • February 2022
      • Case

      Toraya

      By: Lauren Cohen and Akiko Kanno
      Mitsuharu Kurokawa was the 18th generation leader of a family firm that produced and sold premium Japanese sweets, Toraya Confectionery Co., Ltd. He had succeeded the business from his father, Mitsuhiro Kurokawa who had led the firm for thirty years. Mitsuharu was... View Details
      Keywords: Branding; Luxury Brand; Succession; Family Business; Management Succession; Brands and Branding; Luxury; Marketing; Expansion; Globalization; Innovation and Invention; Customer Satisfaction; Food and Beverage Industry; Retail Industry; Japan
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      Cohen, Lauren, and Akiko Kanno. "Toraya." Harvard Business School Case 222-068, February 2022.
      • February 2022 (Revised October 2022)
      • Case

      Ample Hills Creamery

      By: Tom Eisenmann, Lindsay N. Hyde and Tom Quinn
      Ample Hills Creamery started in 2010 as a temporary ice cream pushcart in Brooklyn, New York City. On the strength of inventive flavors and clever marketing, husband-and-wife founders Brian Smith and Jackie Cuscuna built a premium, artisanal dessert empire of 16 retail... View Details
      Keywords: Brands and Branding; Business Growth and Maturation; Partners and Partnerships; Logistics; Profit; Insolvency and Bankruptcy; Food and Beverage Industry
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      Eisenmann, Tom, Lindsay N. Hyde, and Tom Quinn. "Ample Hills Creamery." Harvard Business School Case 822-073, February 2022. (Revised October 2022.)
      • February 2022
      • Case

      Launching the Social

      By: Tom Eisenmann, Lindsay N. Hyde and Tom Quinn
      This case features the same protagonists as Ample Hills Creamery (HBS No. 822-073), and can be used as a continuation of that story.
      Ample Hills Creamery started in 2010 as a temporary ice cream pushcart in Brooklyn, New York City. On the strength of inventive... View Details
      Keywords: Entrepreneurship; Small Business; Brands and Branding; Partners and Partnerships; Expansion
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      Eisenmann, Tom, Lindsay N. Hyde, and Tom Quinn. "Launching the Social." Harvard Business School Case 822-074, February 2022.
      • February 2022 (Revised September 2022)
      • Case

      InstaDeep: AI Innovation Born in Africa (A)

      By: Shikhar Ghosh and Esel Çekin
      Karim Beguir and Zohra Slim were the co-founders of InstaDeep, a deep tech startup focusing on artificial intelligence (AI) solutions. Instadeep was one of the few companies globally that were partnering with DeepMind, an AI subsidiary of Google [Alphabet Inc.].... View Details
      Keywords: AI; Artificial Intelligence; Entrepreneurship; Operations; Business Subsidiaries; Brands and Branding; Innovation and Invention; Growth and Development Strategy; AI and Machine Learning; Technology Industry; Africa
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      Ghosh, Shikhar, and Esel Çekin. "InstaDeep: AI Innovation Born in Africa (A)." Harvard Business School Case 822-104, February 2022. (Revised September 2022.)
      • February 2022 (Revised July 2022)
      • Supplement

      InstaDeep: AI Innovation Born in Africa (B)

      By: Shikhar Ghosh and Esel Çekin
      Karim Beguir and Zohra Slim were the co-founders of InstaDeep, a deep tech startup focusing on artificial intelligence (AI) solutions. Instadeep was one of the few companies globally that were partnering with DeepMind, an AI subsidiary of Google [Alphabet Inc.].... View Details
      Keywords: AI; Artificial Intelligence; Entrepreneurship; Operations; Business Subsidiaries; Brands and Branding; Innovation and Invention; Growth and Development Strategy; AI and Machine Learning; Technology Industry; Africa
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      Ghosh, Shikhar, and Esel Çekin. "InstaDeep: AI Innovation Born in Africa (B)." Harvard Business School Supplement 822-105, February 2022. (Revised July 2022.)
      • 2022
      • Book

      Corporate Explorer: How Corporations Beat Startups at the Innovation Game

      By: Andrew Binns, Charles A. O'Reilly III and Michael Tushman
      Innovation used to be seen as a game best left to entrepreneurs, but now a new breed of corporate managers is flipping this logic on its head. These Corporate Explorers have the insight, resilience, and discipline to overcome the obstacles and build new ventures from... View Details
      Keywords: Organization Change And Adaptation; Disruptive Innovation; Organizational Change and Adaptation; Innovation and Management; Leading Change
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      Binns, Andrew, Charles A. O'Reilly III, and Michael Tushman. Corporate Explorer: How Corporations Beat Startups at the Innovation Game. Hoboken, NJ: Wiley, 2022.
      • 2022
      • Chapter

      Creating 'Smart' Policy to Promote Entrepreneurship and Innovation

      By: Karen G. Mills and Annie Dang
      Entrepreneurship is a key to unlocking innovation and fostering regional and national economic productivity. Extensive studies demonstrate that small and young firms contribute to innovation and employment growth. But which of the many types of small firms are... View Details
      Keywords: Economic Policy; High-growth; Entrepreneurship; Innovation and Invention; Business Startups; Economic Growth; Policy; United States
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      Mills, Karen G., and Annie Dang. "Creating 'Smart' Policy to Promote Entrepreneurship and Innovation." In The Role of Innovation and Entrepreneurship in Economic Growth, edited by Michael J. Andrews, Aaron Chatterji, Josh Lerner, and Scott Stern. Chicago: University of Chicago Press, 2022.
      • Winter 2022
      • Article

      Leading Disruption in a Legacy Business: A Compelling Growth Ambition Is a Critical Enabler for New Ventures

      By: Andy Binns, Michael Tushman and Charles O'Reilly
      Leading innovation in established corporations is difficult. Active inertia and dynamic conservatism are real. Still, leaders can drive disruptive ventures from inside large corporations. These leaders ideate, incubate, and scale innovations, much as an entrepreneur... View Details
      Keywords: Disruptive Innovation; Innovation and Management; Leading Change; Organizational Change and Adaptation; Business Model
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      Binns, Andy, Michael Tushman, and Charles O'Reilly. "Leading Disruption in a Legacy Business: A Compelling Growth Ambition Is a Critical Enabler for New Ventures." MIT Sloan Management Review 63, no. 2 (Winter 2022).
      • 2022
      • Article

      Missing Novelty in Drug Development

      By: Joshua Krieger, Danielle Li and Dimitris Papanikolaou
      We provide evidence that risk aversion leads pharmaceutical firms to underinvest in radical innovation. We introduce a new measure of drug novelty based on chemical similarity and show that firms face a risk-reward trade-off: novel drug candidates are less likely to... View Details
      Keywords: Drug Development; Risk Aversion; Research and Development; Innovation and Invention; Investment; Pharmaceutical Industry
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      Krieger, Joshua, Danielle Li, and Dimitris Papanikolaou. "Missing Novelty in Drug Development." Review of Financial Studies 35, no. 2 (February 2022): 636–679.
      • February 2022
      • Article

      Taxation and Innovation in the 20th Century

      By: Ufuk Akcigit, John Grigsby, Tom Nicholas and Stefanie Stantcheva
      This paper studies the effect of corporate and personal taxes on innovation in the United States over the twentieth century. We build a panel of the universe of inventors who patent since 1920, and a historical state-level corporate tax database with corporate tax... View Details
      Keywords: Innovation; Income Taxes; Corporate Taxation; Firms; Inventors; State Taxation; Business Taxation; R&D Tax Credits; Taxation; Innovation and Invention; History; United States
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      Akcigit, Ufuk, John Grigsby, Tom Nicholas, and Stefanie Stantcheva. "Taxation and Innovation in the 20th Century." Quarterly Journal of Economics 137, no. 1 (February 2022): 329–385.
      • 2022
      • Book

      The Role of Innovation and Entrepreneurship in Economic Growth

      By: Michael J. Andrews, Aaron Chatterji, Josh Lerner and Scott Stern
      We live in an era in which innovation and entrepreneurship seem ubiquitous, particularly in regions like Silicon Valley, Boston, and the Research Triangle Park. But many metrics of economic growth, such as productivity growth and business dynamism, have been at best... View Details
      Keywords: Productivity Growth; Production Technologies; Innovation and Invention; Entrepreneurship; Economic Growth; Competition; Organizational Design; Economic Slowdown and Stagnation
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      Andrews, Michael J., Aaron Chatterji, Josh Lerner, and Scott Stern, eds. The Role of Innovation and Entrepreneurship in Economic Growth. Chicago: University of Chicago Press, 2022.
      • 2022
      • Chapter

      The Servicification of the U.S. Economy: The Role of Startups versus Incumbent Firms

      By: Mercedes Delgado, J. Daniel Kim and Karen G. Mills
      Over the last few decades, the U.S. economy has exhibited a significant shift from manufacturing towards services. This transition has been particularly prominent in an important subcategory of services industries that drives innovation and employs many high-wage... View Details
      Keywords: Servicification; Supply Chain Industries; STEM Labor; Innovation; Growth; Entrepreneurship; Innovation and Invention; Economic Growth; Policy; Service Industry; United States
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      Delgado, Mercedes, J. Daniel Kim, and Karen G. Mills. "The Servicification of the U.S. Economy: The Role of Startups versus Incumbent Firms." In The Role of Innovation and Entrepreneurship in Economic Growth, edited by Michael J. Andrews, Aaron Chatterji, Josh Lerner, and Scott Stern. Chicago: University of Chicago Press, 2022.
      • January 2022
      • Supplement

      Somatus: Value-Based Kidney Care (B)

      By: Ariel D. Stern, Robert S. Huckman and Sarah Mehta
      Set in early 2020, this (B) case provides an update to the (A) case (no. 622-009) and provides additional context regarding the challenges facing Somatus. View Details
      Keywords: Business Startups; Disruption; Entrepreneurship; Health; Health Care and Treatment; Health Disorders; Medical Specialties; Innovation and Invention; Disruptive Innovation; Management; Strategy; Business Strategy; Value; Value Creation; Health Industry; United States; Virginia
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      Stern, Ariel D., Robert S. Huckman, and Sarah Mehta. "Somatus: Value-Based Kidney Care (B)." Harvard Business School Supplement 622-045, January 2022.
      • January 2022
      • Case

      Tomorrow.io Goes to Space

      By: Joshua Lev Krieger, Abhishek Nagaraj and James Barnett
      This case study explores the evolution of Tomorrow.io, a weather forecasting technology company, as it pivoted toward building and launching space-based weather radar satellites. This strategic shift was driven by the company's ambition to overcome data limitations in... View Details
      Keywords: Communication; Competency and Skills; Engineering; Globalization; Innovation and Invention; Performance; Information Technology; Aerospace Industry
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      Krieger, Joshua Lev, Abhishek Nagaraj, and James Barnett. "Tomorrow.io Goes to Space." Harvard Business School Case 822-005, January 2022.
      • 2022
      • Working Paper

      Talent Flows and the Geography of Knowledge Production: Causal Evidence from Multinational Firms

      By: Dany Bahar, Prithwiraj Choudhury, Sara Signorelli and James M. Sappenfield
      Leveraging a unique dataset merging patent data with all work-related migration reforms that took place in 15 countries over 26 years, we show that reforms discouraging inventor mobility decrease the patenting of MNE subsidiaries within a country, while reforms... View Details
      Keywords: Migration; Technology; Policy Evaluation; Patents; Information Technology; Immigration; Policy; Collaborative Innovation and Invention; Globalization
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      Bahar, Dany, Prithwiraj Choudhury, Sara Signorelli, and James M. Sappenfield. "Talent Flows and the Geography of Knowledge Production: Causal Evidence from Multinational Firms." Harvard Business School Working Paper, No. 22-047, January 2022. (Revised December 2022.)
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