Publications

September 2000
Case

Novartis Agricultural Discovery Institute (A)

Steve Briggs, a PhD biologist, is asked to propose a strategy to take global life-science giant Novartis into the rapidly expanding field of plant genomics. View Details

Keywords: Design; Plant-Based Agribusiness; Genetics; Infrastructure; Biotechnology Industry; Biotechnology Industry

April 1998 (Revised June 1998)
Supplement

Pioneer Hi-Bred International, Inc.: Supply Management (Addendum)

By: Francis Aguilar, Paul Clark and Xin Xi He

Addendum to case. View Details

Keywords: Agriculture and Agribusiness Industry; Agriculture and Agribusiness Industry

October 1998 (Revised December 1999)
Case

Gene Research, the Mapping of Life and the Global Economy

By: Ray A. Goldberg and Juan Enriquez-Cabot

A new firm is being created to speed up the process of mapping humans, animals, and plants by combining gene technology with rapid gene identification to improve the health and well being of the human population and the productivity of crops and animals. How does one... View Details

Keywords: Information Technology; Organizational Structure; Technological Innovation; Business Processes; Health Care and Treatment; Performance Productivity; Welfare; Agribusiness; Genetics; Science-Based Business; Biotechnology Industry; Biotechnology Industry

11 May 2010
First Look

First Look: May 11

Amyris Biotechnologies: Commercializing Biofuel Gary P. Pisano and Alison Berkley WagonfeldHarvard Business School Case 610-031 In 2009, Amyris Biotechnologies was building a plant in Brazil that used synthetic biology to convert... View Details

Keywords: Martha Lagace

11 Sep 2007
First Look

First Look: September 11, 2007

and deliverables. Many critical business challenges are detailed in this case. Nevertheless, given their fully integrated business model and significant manufacturing base, the odds are in Biocon's favor to overcome these challenges and lead India's View Details

Keywords: Martha Lagace

Sep 2011 - 2011
Conference Presentation

From Farms to Fuel Tanks: Collective Actors and New-venture Innovation in the U.S. Biodiesel Sector

By: Shon R. Hiatt

Keywords: Innovation and Invention; Energy Industry; Energy Industry; Energy Industry

12 May 2009
First Look

First Look: May 12, 2009

illustrates how deep dives guide the formation of a set of new core activities in the variation-selection-retention process. No PDF is available at this time. PublicationsWhat Causes Industry Agglomeration? Evidence from Coagglomeration... View Details

Keywords: Martha Lagace

March 2023
Case

Moderna

By: Marco Iansiti, Karim R. Lakhani, Hannah Mayer, Kerry Herman, Allison J. Wigen and Dave Habeeb

This multimedia case follows the story of Moderna and its entry into vaccine development in the wake of the COVID-19 pandemic. In summer 2020, Stephane Bancel, CEO of biotech firm Moderna, faces several challenges as his company races to develop a vaccine for COVID-19.... View Details

Keywords: Health Pandemics; Research and Development; Digital Transformation; Health Testing and Trials; Biotechnology Industry; Biotechnology Industry

March 2022
Teaching Note

Digital Manufacturing at Amgen

By: Shane Greenstein, Kyle R. Myers and Sarah Mehta

This teaching note provides guidance for instructors teaching “Digital Manufacturing at Amgen,” case no. 621-008. View Details

November 2020
Supplement

Valuing Celgene's CVR

By: Benjamin C. Esty and Daniel Fisher

When Bristol-Myers Squibb (BMS) acquired Celgene Corporation in November 2019, Celgene shareholders received cash, BMS stock, and a contingent value right (CVRs) that would pay $9 if the U.S. Food and Drug Administration (FDA) approved three of Celgene’s late stage... View Details

Keywords: Mergers and Acquisitions; Value; Valuation; Judgments; Decision Making; Cash Flow; Financial Instruments; Cognition and Thinking; Pharmaceutical Industry; Pharmaceutical Industry; United States

October 2019 (Revised April 2020)
Background Note

Note on Funding Deep Tech Startups

By: Karim Lakhani, Peter Barrett and Noubar Afeyan

This Background Note provides essential information on funding deep technologies—those technologies that were inherently capital intensive, time consuming, risky, and potentially disruptive. Both dilutive and non-dilutive sources of investment are highlighted, along... View Details

September 2019
Case

Celgene: Business Development and Distributed Research

By: Peter Barrett and Kareem Reda

This case looks at the deal-making process between Celgene, a large publicly traded pharmaceutical company, and Agios, an early-stage biotech company. The framework of a potential deal is explored and the potential road-blocks to Agios’ profitability are discussed. ... View Details

Keywords: Negotiation Deal; Alliances; Collaborative Innovation and Invention; Research; Pharmaceutical Industry; Pharmaceutical Industry

June 2014
Supplement

Merrimack Pharmaceuticals, Inc. (B)

By: Amy C. Edmondson, Bethany Gerstein and Melissa Valentine

In 2006, the leadership team at Merrimack Pharmaceuticals, Inc. had to decide whether to keep its R&D organization in functional departments or restructure it into interdisciplinary teams. This case follows the outcomes of this decision from 2006 to mid-2014, and... View Details

Keywords: Organizational Design; Groups and Teams; Collaborative Innovation and Invention; Research and Development; Biotechnology Industry; Biotechnology Industry

April 2010
Teaching Note

The DiagnoFirst Opportunity (TN)

By: Robert C. Pozen

Teaching Note for [309112]. View Details

Keywords: Decisions; Investment; Risk and Uncertainty; Patents; Cash Flow; Venture Capital; Negotiation Deal; Health Care and Treatment; Opportunities; Law; Health Industry; Health Industry; United States; Europe