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04 Jun 2012
Research & Ideas

The Business of Life

sticking to principles every day, considering all the hard work involved. "He told me he thought it had 'a negative net present value.'" “It's a travesty that somehow our society has gotten to a point where people have the view that View Details

Keywords: by Carmen Nobel

March 2023
Case

Azenta Life Sciences: The Road to Transformation

By: Gary P. Pisano and Catherine Piner

When the Board brought Steve Schwartz in as President of Brooks Automation in 2010, they gave him a clear mission: strengthen the company’s core semiconductor equipment business and find a new industry to enter. Over the course of the next decade, Schwartz and the... View Details

Keywords: Transformation; Business and Shareholder Relations; Market Entry and Exit; Organizational Change and Adaptation; Segmentation; Technology Industry

2010
Working Paper

From Bench to Board: Gender Differences in University Scientists' Participation in Commercial Science

This paper examines gender differences in the participation of university life science faculty in commercial science. Based on theory and field interviews, we develop hypotheses regarding how scientists' productivity, co-authorship networks, and institutional... View Details

Keywords: Business Startups; For-Profit Firms; Gender Characteristics; Higher Education; Entrepreneurship; Governing and Advisory Boards; Science-Based Business; Nonprofit Organizations; Biotechnology Industry

January 2014 (Revised December 2014)
Case

GenapSys: Business Models for the Genome

By: Richard G. Hamermesh, Joseph B. Fuller and Matthew Preble

GenapSys, a California-based startup, was soon to release a new DNA sequencer that the company's founder, Hesaam Esfandyarpour, believed was truly revolutionary. The sequencer would be substantially less expensive—potentially costing just a few thousand dollars—and... View Details

Keywords: DNA Sequencing; Life Sciences; Business Model; Innovation ＆ Entrepreneurship; Health Care and Treatment; Genetics; Business Strategy; Biotechnology Industry; Pharmaceutical Industry; Technology Industry; Health Industry; Medical Devices and Supplies Industry; United States

May 2017
Teaching Plan

Neurotrack and the Alzheimer's Puzzle

By: Richard G. Hamermesh and Carin-Isabel Knoop

Teaching Note for HBS No. 816-072. View Details

Keywords: Health Care; Alzheimer's Disease; Career Path; Life Science Business

December 2020 (Revised February 2021)
Case

Kerry Group: Inspiring Food, Nourishing Life

By: Forest L. Reinhardt, José B. Alvarez, Damien McLoughlin, Tonia Labruyere and Tonia Junker

The Irish company Kerry Group, one of the leading global players in the taste and nutrition industry, wants to ensure its future growth in developing and developed markets. Founded in 1972 as a dairy cooperative, it had grown into a provider of taste and nutrition... View Details

Keywords: Agribusiness; Environmental Sustainability; Food; Nutrition; Growth and Development Strategy; Global Range; Market Entry and Exit; Customer Relationship Management; Agriculture and Agribusiness Industry

March 2018 (Revised May 2018)
Supplement

Celgene (B)

By: Malcolm Baker and Emily McComb

Supplements the (A) case. View Details

Keywords: Life Sciences; Biotechnology; Public Market Investing; Celgene; Revlimid; Hedge Fund; Growth Stocks; Valuation; Investment; Decision Choices and Conditions; Analysis; Biotechnology Industry

Article

What to Know About Locating in a Cluster

By: Willy C. Shih and Sen Chai

As a study of two industry clusters in Denmark shows, factors that can make clusters attractive—easy people movement and knowledge spillovers—can also make it harder for individual companies to retain proprietary knowledge. View Details

Keywords: Clusters; Clustering; Competitiveness; Life Sciences; Telecommunications; Science-based; Research And Development; Industry Clusters; Research; Innovation Strategy; Innovation and Management; Geographic Location; Pharmaceutical Industry; Biotechnology Industry; Telecommunications Industry; Food and Beverage Industry; Denmark

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February 2014
Case

BGI: Data-driven Research

By: Willy Shih and Sen Chai

BGI has the largest installed gene-sequencing capacity in the world, and to Zhang Gengyun, general manager of the Life Sciences Division, this represented an opportunity to apply his training as a plant breeder and his early career work as a biochemist to improving... View Details

April 2018
Supplement

Celgene

By: Malcolm Baker and Emily R. McComb

In February 2011, Adam Koppel, a Managing Director at Brookside Capital, the public equity arm of Bain Capital, must decide whether to increase or exit the firm’s position in Celgene Corporation. News has emerged that raises potential safety concerns associated with... View Details

Keywords: Life Sciences; Biotechnology; Public Market Investing; Celgene; Revlimid; Hedge Fund; Growth Stocks; Valuation; Investment; Decision Choices and Conditions; Analysis

December 2005 (Revised October 2013)
Case

Fred Khosravi and AccessClosure (A)

By: Richard Hamermesh and Liz Kind

Fred Khosravi is a serial medical device entrepreneur. In his latest venture, he must decide whether to sell now or continue to develop his current product and whether to market it, sell the company, or IPO. View Details

Keywords: Negotiation; Medical Devices; Venture Capital; Life Sciences; Health Care Industry; Healthcare Technology; Healthcare Ventures; Business Startups; Decision Choices and Conditions; Entrepreneurship; Growth and Development Strategy; Medical Devices and Supplies Industry; United States

March 2018 (Revised May 2018)
Case

Celgene

By: Malcolm Baker and Emily McComb

In February 2011, Adam Koppel, a managing director at Brookside Capital, the public equity arm of Bain Capital, must decide whether to increase or exit the firm’s position in Celgene Corporation. News has emerged that raises potential safety concerns associated with... View Details

Keywords: Life Sciences; Biotechnology; Public Market Investing; Celgene; Revlimid; Hedge Fund; Growth Stocks; Valuation; Investment; Decision Choices and Conditions; Analysis; Biotechnology Industry

March 2011
Case

Padraig O'Ceidigh and Aer Arann: Building a Business in the Context of a Life

By: Janet J. Kraus and Shirley Spence

In April 2010, the eruption of a volcano wreaked havoc in the airline industry and placed Aer Arann on the bring of liquidation. For founder, sole owner and chairman Padraig O'Ceidigh, the airline has been a personal as well as business passion. The case provides a... View Details

Keywords: Natural Disasters; Crisis Management; Air Transportation; Entrepreneurship; Management Teams; Business or Company Management; Success; Decision Making; Air Transportation Industry; Republic of Ireland

October 1998 (Revised December 1999)
Case

Gene Research, the Mapping of Life and the Global Economy

By: Ray A. Goldberg and Juan Enriquez-Cabot

A new firm is being created to speed up the process of mapping humans, animals, and plants by combining gene technology with rapid gene identification to improve the health and well being of the human population and the productivity of crops and animals. How does one... View Details

Keywords: Information Technology; Organizational Structure; Technological Innovation; Business Processes; Health Care and Treatment; Performance Productivity; Welfare; Agribusiness; Genetics; Science-Based Business; Biotechnology Industry; Agriculture and Agribusiness Industry

03 Oct 2023
Research Event

Build the Life You Want: Arthur Brooks and Oprah Winfrey Share Happiness Tips

coauthor of the new book Build the Life You Want: The Art and Science of Getting Happier, for an intimate, powerful conversation that touches on: the mistake people make in thinking that money, power, and... View Details

Keywords: by HBS Staff

January 2024
Article

Helping Children Catch Up: Early Life Shocks and the PROGRESA Experiment

By: Achyuta Adhvaryu, Theresa Molina, Anant Nyshadham and Jorge Tamayo

Can investing in children who faced adverse events in early childhood help them catch up? We answer this question using two orthogonal sources of variation – resource availability at birth (local rainfall) and cash incentives for school enrollment – to identify the... View Details

Keywords: Children; Outcome or Result; Welfare; Early Childhood Education; Weather

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January 2017
Case

Danaher Corporation, 2007–2017

By: John R. Wells and Gabriel Ellsworth

On July 2, 2016, Danaher Corporation completed the spinoff of Fortive Corporation. The previous day, Danaher’s stock price had reached an all-time high. In 2015, Danaher had decided to split off its test and measurement, fuel and fleet management, and automation... View Details

Keywords: Danaher; Fortive; Larry Culp; Beckman Coulter; Pall; Life Sciences; Diagnostics; Environmental Operations; Water Management; Dental; Testing; Measurement; Fuel; Fleet Management; Automation; Toolmaking; Tools; Disease Management; Continuous Improvement; Toyota Production System; Divestiture; Spinoffs; Spin-off; Networks; Acquisition; Mergers and Acquisitions; Business Conglomerates; Business Divisions; Business Subsidiaries; Business Units; Business Growth and Maturation; Business Model; For-Profit Firms; Joint Ventures; Restructuring; Engineering; Chemicals; Construction; Machinery and Machining; Profit; Revenue; Globalized Firms and Management; Multinational Firms and Management; Health; Health Care and Treatment; Health Disorders; Medical Specialties; Business History; Job Cuts and Outsourcing; Business or Company Management; Growth and Development Strategy; Management Analysis, Tools, and Techniques; Management Practices and Processes; Management Succession; Management Systems; Resource Allocation; Market Entry and Exit; Measurement and Metrics; Logistics; Business Processes; Organizational Change and Adaptation; Public Ownership; Problems and Challenges; Science; Genetics; Natural Environment; Wastes and Waste Processing; Science-Based Business; Opportunities; Strategy; Adaptation; Business Strategy; Competition; Competitive Strategy; Competitive Advantage; Consolidation; Corporate Strategy; Diversification; Expansion; Technology; Software; Technology Networks; Technology Platform; Value; Valuation; Aerospace Industry; Auto Industry; Biotechnology Industry; Chemical Industry; Computer Industry; Construction Industry; Consumer Products Industry; Distribution Industry; Electronics Industry; Food and Beverage Industry; Health Industry; Industrial Products Industry; Information Technology Industry; Manufacturing Industry; Medical Devices and Supplies Industry; Pharmaceutical Industry; Retail Industry; Rubber Industry; Semiconductor Industry; Shipping Industry; Technology Industry; Telecommunications Industry; Utilities Industry; United States; District of Columbia

January 2018
Article

Big Data and Big Cities: The Promises and Limitations of Improved Measures of Urban Life

By: Edward L. Glaeser, Scott Duke Kominers, Michael Luca and Nikhil Naik

New, "big" data sources allow measurement of city characteristics and outcome variables at higher frequencies and finer geographic scales than ever before. However, big data will not solve large urban social science questions on its own. Big data has the most value for... View Details

Keywords: Analytics and Data Science; Urban Scope; City

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Article

Multivoxel Patterns in Face-sensitive Temporal Regions Reveal an Encoding Schema Based on Detecting Life in a Face

By: Christine E. Looser, J. Swaroop Guntupalli and Thalia Wheatley

More than a decade of research has demonstrated that faces evoke prioritized processing in a 'core face network' of three brain regions. However, whether these regions prioritize the detection of global facial form (shared by humans and mannequins) or the detection of... View Details

Keywords: Brain Imaging; Social Psychology; Mind Perception; Identity; Science; Cognition and Thinking

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Teaching Interest

Overview

Teaching has been a lifelong passion of mine. As the third generation of academics in my family, I see good teaching as a means to give back and to encourage others to share my passion for discovery. I’ve been very lucky to have many teaching opportunities, both as an... View Details

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