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- Faculty Publications (38)
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- All HBS Web (159)
- Faculty Publications (38)
- 2009
- Article
Synthesis by Microbes or Chemists? Pharmaceutical Research and Manufacturing in the Antibiotic Era
By: Arthur A. Daemmrich
This article presents a case study of the rise of Pfizer as a leading pharmaceutical company, with a focus on changing relationships between manufacturing technology and R&D between the mid-1940s and the mid-1960s. Pfizer first moved into pharmaceuticals through... View Details
Keywords: Research and Development; Production; Technology; Transformation; Relationships; Success; Organizations; Programs; Chemicals; Alignment; Pharmaceutical Industry; United States
Daemmrich, Arthur A. "Synthesis by Microbes or Chemists? Pharmaceutical Research and Manufacturing in the Antibiotic Era." History and Technology 23, no. 3 (2009): 237–256.
- Article
Capabilities, Cognition and Inertia: Evidence from Digital Imaging
By: M. Tripsas and G. Gavetti
There is empirical evidence that established firms often have difficulty adapting to radical technological change. Although prior work in the evolutionary tradition emphasizes the inertial forces associated with the local nature of learning processes, little... View Details
Tripsas, M., and G. Gavetti. "Capabilities, Cognition and Inertia: Evidence from Digital Imaging." Strategic Management Journal 21, nos. 10-11 (October–November 2000): 1147–1161.
- December 2010 (Revised January 2011)
- Supplement
Qualcomm Incorporated 2011 Update
By: David B. Yoffie
Qualcomm in 2009 and 2010 experienced both the worst of times and the best of times. During the "great recession" of 2009, smartphones growth stalled, stalling Qualcomm's revenue, but in 2010 growth surged again, and was predicted to continue its upward trajectory in... View Details
Keywords: Television Entertainment; Growth and Development Strategy; Opportunities; Mobile and Wireless Technology; Telecommunications Industry
Yoffie, David B. "Qualcomm Incorporated 2011 Update." Harvard Business School Supplement 711-463, December 2010. (Revised January 2011.)
- July 2023 (Revised May 2024)
- Case
Vytal: Packaging-as-a-Service
By: George Serafeim, Michael W. Toffel, Lena Duchene and Daniela Beyersdorfer
The Germany-based startup Vytal operated the largest digital-native reusable packaging-as-a-service network globally, having raised nearly €15 million, established a large network of restaurant partners, and prevented the use of millions of single-use take-out food... View Details
Keywords: Climate Risk; Digital; Platform Strategies; Data; Packaging; Sustainability; Start-up; Startup; Entrepreneur; Impact; Circular; Growth Strategy; Innovation; Environmental Sustainability; Innovation and Invention; Business Growth and Maturation; Growth and Development Strategy; Business Startups; Resource Allocation; Risk Management; Adoption; Strategy; Performance Productivity; Service Delivery; Service Operations; Supply Chain; Distribution; Entrepreneurship; Climate Change; Green Technology Industry; Service Industry; Retail Industry; Germany; Europe
Serafeim, George, Michael W. Toffel, Lena Duchene, and Daniela Beyersdorfer. "Vytal: Packaging-as-a-Service." Harvard Business School Case 124-007, July 2023. (Revised May 2024.)
- 2015
- Chapter
Innovation and Entrepreneurship in Renewable Energy
By: Ramana Nanda, Ken Younge and Lee Fleming
We document three facts related to innovation and entrepreneurship in renewable energy. Using data from the U.S. Patent and Trademark Office, we first show that patenting in renewable energy remains highly concentrated in a few large energy firms. In 2009, the top 20... View Details
Keywords: Entrepreneurial Finance; Entrepreneurial Management; Energy; Finance; Entrepreneurship; Energy Industry
Nanda, Ramana, Ken Younge, and Lee Fleming. "Innovation and Entrepreneurship in Renewable Energy." Chap. 7 in The Changing Frontier: Rethinking Science and Innovation Policy, edited by Adam Jaffe and Benjamin Jones, 199–232. University of Chicago Press, 2015.
- December 2021
- Article
The Evolutionary Nature of Breakthrough Innovation: An Empirical Investigation of Firm Search Strategies
By: Dominika Kinga Randle and Gary P. Pisano
Breakthrough innovation has been an important topic of study for generations of scholars. Previous research in this domain has focused on exploring the way breakthroughs emerge from cumulative combination and recombination of prior technologies and knowledge components... View Details
Keywords: Breakthrough Innovation; Exploration And Exploitation; Search Strategy; Innovation and Invention; Technological Innovation; Strategy
Randle, Dominika Kinga, and Gary P. Pisano. "The Evolutionary Nature of Breakthrough Innovation: An Empirical Investigation of Firm Search Strategies." Strategy Science 6, no. 4 (December 2021): 290–304.
- 2022
- Working Paper
Are Experts Blinded by Feasibility?: Experimental Evidence from a NASA Robotics Challenge
By: Jacqueline N. Lane, Zoe Szajnfarber, Jason Crusan, Michael Menietti and Karim R. Lakhani
Resource allocation decisions play a dominant role in shaping a firm’s technological trajectory and competitive advantage. Recent work indicates that innovative firms and scientific institutions tend to exhibit an anti-novelty bias when evaluating new projects and... View Details
Keywords: Evaluations; Novelty; Feasibility; Field Experiment; Resource Allocation; Technological Innovation; Competitive Advantage; Decision Making
Lane, Jacqueline N., Zoe Szajnfarber, Jason Crusan, Michael Menietti, and Karim R. Lakhani. "Are Experts Blinded by Feasibility? Experimental Evidence from a NASA Robotics Challenge." Harvard Business School Working Paper, No. 22-071, May 2022.
- August 2015
- Case
Yabbly (A)
By: Shikhar Ghosh and Christopher Payton
In November 2013, with less than 10 months of cash on hand, Tom Leung, the founder and CEO of Yabbly, must decide where to focus his resources. His startup, a question-and-answer application for shopping decisions, had benefited from a strong showing at the SXSW... View Details
Keywords: Startup; Mobile; Online Product Reviews; Consumer Products; Business Model; Business Plan; Business Startups; Entrepreneurship; Innovation Strategy; Mobile and Wireless Technology; Internet and the Web; North America; United States; Washington (state, US); Seattle
Ghosh, Shikhar, and Christopher Payton. "Yabbly (A)." Harvard Business School Case 816-030, August 2015.
- 2021
- Article
Venture Capital Booms and Startup Financing
By: William Janeway, Ramana Nanda and Matthew Rhodes-Kropf
We review the growing literature on the relationship between venture capital booms and startup financing, focusing on three broad areas: First, we discuss the drivers of large inflows into the venture capital asset class, particularly in recent years—which are related... View Details
Janeway, William, Ramana Nanda, and Matthew Rhodes-Kropf. "Venture Capital Booms and Startup Financing." Annual Review of Financial Economics 13 (2021): 111–127.
- December 2019 (Revised September 2020)
- Case
Facebook Faces the Regulators
By: Debora L. Spar
In the fall of 2019, Facebook and its CEO Mark Zuckerberg are facing increased scrutiny on multiple fronts. Regulators from around the globe are threatening the company with punitive measures. Users are organizing against it. But there is little consensus around what,... View Details
Keywords: Facebook; Regulation; Media; Internet and the Web; Governance; Governing Rules, Regulations, and Reforms; Business and Government Relations; Social Media; Europe
Spar, Debora L. "Facebook Faces the Regulators." Harvard Business School Case 720-019, December 2019. (Revised September 2020.)
- April 2021
- Case
Distinct Software
By: Das Narayandas, Arijit Sengupta and Jonathan Wray
Distinct Software (disguised name), a global enterprise software company, is at an important point in its growth trajectory where the luster of its mantra of “grow and win at any cost” has dimmed with increasing competition and margin pressures. To help navigate its... View Details
Keywords: Artificial Intelligence; Marketing; Sales; Performance Productivity; Technological Innovation; AI and Machine Learning
Narayandas, Das, Arijit Sengupta, and Jonathan Wray. "Distinct Software." Harvard Business School Case 521-101, April 2021.
- 01 Dec 2014
- Working Paper Summaries
Financing Innovation
Keywords: by William R. Kerr & Ramana Nanda
- 2022
- Working Paper
Can a Website Bring Unemployment Down? Experimental Evidence from France
By: Aïcha Ben Dhia, Bruno Crépon, Esther Mbih, Louise Paul-Delvaux, Bertille Picard and Vincent Pons
We evaluate the impact of an online platform giving job seekers tips to improve their search and recommendations of new occupations and locations to target, based on their personal data and labor market data. Our experiment used an encouragement design and was... View Details
Keywords: Online Platform; Digital Platform; Unemployment; Encouragement Design; Job Search; Jobs and Positions; Internet and the Web; Well-being; Outcome or Result; Digital Platforms; France
Ben Dhia, Aïcha, Bruno Crépon, Esther Mbih, Louise Paul-Delvaux, Bertille Picard, and Vincent Pons. "Can a Website Bring Unemployment Down? Experimental Evidence from France." NBER Working Paper Series, No. 29914, April 2022.
- October 2022
- Case
Ethena: A Go-to-Market Dilemma
By: Rembrand Koning and Stacy Straaberg
In November 2021, Roxanne Petraeus and Anne Solmssen, founders of Brooklyn-based software-as-a-service (SaaS) startup Ethena, were looking to expand their compliance training business. The founders hired Arnie Gullov-Singh, an outside revenue consultant, to advise on... View Details
Keywords: Decision Choices and Conditions; Judgments; Growth and Development Strategy; Business or Company Management; Business Strategy; Expansion; Segmentation; Technology Industry; United States; New York (state, US)
Koning, Rembrand, and Stacy Straaberg. "Ethena: A Go-to-Market Dilemma." Harvard Business School Case 723-363, October 2022.
- September 2017
- Case
Christine Lagarde
By: Julie Battilana, Carin-Isabel Knoop, Vanessa Ampelas and Noemie Assenat
The case covers the youth and career trajectory of Christine Lagarde across her time at Baker & McKenzie, as a minister in the government of France and as the head of the International Monetary Fund (IMF). The case highlights the challenges and opportunities she faced... View Details
Keywords: Change; Personal Development and Career; Power and Influence; Leadership; Gender; Leading Change
Battilana, Julie, Carin-Isabel Knoop, Vanessa Ampelas, and Noemie Assenat. "Christine Lagarde." Harvard Business School Case 418-007, September 2017.
- 17 May 2011
- First Look
First Look: May 17
http://papers.nber.org/papers/w16922 Historical Trajectories and Corporate Competences in Wind Energy Authors:Geoffrey Jones and Loubna Bouamane Abstract This working paper surveys the business history of the global wind energy turbine... View Details
Keywords: Sean Silverthorne
- Article
Paradise Lost (and Restored?): A Study of Psychological Safety over Time
By: Derrick P. Bransby, Michaela Kerrissey and Amy C. Edmondson
Although prior research indicates that psychological safety can fluctuate, questions about when and why remain. To gain insights into the emergence and temporal dynamics of psychological safety, we explored longitudinal data representing more than 10,000 health care... View Details
Keywords: Analytics and Data Science; Research; Attitudes; Working Conditions; Well-being; Health Industry
Bransby, Derrick P., Michaela Kerrissey, and Amy C. Edmondson. "Paradise Lost (and Restored?): A Study of Psychological Safety over Time." Academy of Management Discoveries (in press). (Pre-published online March 14, 2024.)
- 15 Oct 2013
- First Look
First Look: October 15
Depression? By: Nanda, Ramana, and Tom Nicholas Abstract—We find a negative relationship between bank distress and the level, quality, and trajectory of firm-level innovation during the Great Depression, particularly for R&D firms... View Details
Keywords: Sean Silverthorne
- 16 Apr 2001
- Research & Ideas
Angels Face the Innovator’s Dilemma
The venture capital industry is ripe for disruption: just like other leading mainstream companies have been for years, according to HBS professor Clayton M. Christensen. As a keynote speaker at the conference and author of the managerial bible The Innovator's Dilemma:... View Details
- August 2018
- Case
Christine Lagarde
By: Julie Battilana, Carin-Isabel Knoop, Vanessa Ampelas and Noemie Assenat
For a modular presentation of the same material, please see “Christine Lagarde (A): A French Prime Minister Calls” (HBS No. 419-017), “Christine Lagarde (B): Being a Public Servant” (HBS No. 419-018), and “Christine Lagarde (C): Managing the IMF” (HBS No. 419-019).... View Details
Keywords: Change; Personal Development and Career; Power and Influence; Leadership; Gender; Leading Change
Battilana, Julie, Carin-Isabel Knoop, Vanessa Ampelas, and Noemie Assenat. "Christine Lagarde." Harvard Business School Case 419-016, August 2018.