Publications

06 Jun 2016
Research & Ideas

Skills and Behaviors that Make Entrepreneurs Successful

can include small “lifestyle” businesses, multi-generational family businesses, high-growth, venture funded technology businesses, and new ventures designed to commercialize breakthrough discoveries in life sciences, clean tech, and other View Details

Keywords: by HBS Working Knowledge

June 2023
Article

How New Ideas Diffuse in Science

By: Mengjie Cheng, Daniel Scott Smith, Xiang Ren, Hancheng Cao, Sanne Smith and Daniel A. McFarland

What conditions help new ideas spread? Can knowledge entrepreneurs’ position and develop new ideas in ways that help them take off? Most innovation research focuses on products and their reference. That focus ignores the ideas themselves and the broader ideational... View Details

Keywords: Innovation Adoption; Natural Language Processing; Knowledge; Science; Innovation and Invention; Knowledge Sharing; Analytics and Data Science

Research Summary

Overview

Professor Myers studies the ways people learn from their own—and others’—experiences at work, with a particular emphasis on learning in health care organizations and emergency medical contexts. Though his interest is in individual-level learning, he focuses in... View Details

Keywords: Learning And Development; Learning Organizations; Learning By Doing; Health Care Industry; Innovation; Identity Construction; Medical Error; Knowledge Development; Knowledge Sharing; Knowledge Work; Learning; Leadership Development; Knowledge Management; Collaborative Innovation and Invention; Health Industry; United States; Singapore; Asia

2020
Working Paper

When Do Experts Listen to Other Experts? The Role of Negative Information in Expert Evaluations for Novel Projects

By: Jacqueline N. Lane, Misha Teplitskiy, Gary Gray, Hardeep Ranu, Michael Menietti, Eva C. Guinan and Karim R. Lakhani

The evaluation of novel projects lies at the heart of scientific and technological innovation, and yet literature suggests that this process is subject to inconsistency and potential biases. This paper investigates the role of information sharing among experts as the... View Details

Keywords: Project Evaluation; Innovation; Knowledge Frontier; Negativity Bias; Projects; Innovation and Invention; Information; Diversity; Judgments

SSRN

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2015
Working Paper

Public R&D Investments and Private-sector Patenting: Evidence from NIH Funding Rules

By: Pierre Azoulay, Joshua S. Graff Zivin, Danielle Li and Bhaven N. Sampat

We quantify the impact of scientific grant funding at the National Institutes of Health (NIH) on patenting by pharmaceutical and biotechnology firms. Our paper makes two contributions. First, we use newly constructed bibliometric data to develop a method for flexibly... View Details

Keywords: Economics Of Science; Patenting; Academic Reserach; NIH; Knowledge Spillovers; Patents; Research; Government and Politics

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June 2022
Article

Conservatism Gets Funded? A Field Experiment on the Role of Negative Information in Novel Project Evaluation

By: Jacqueline N. Lane, Misha Teplitskiy, Gary Gray, Hardeep Ranu, Michael Menietti, Eva C. Guinan and Karim R. Lakhani

The evaluation and selection of novel projects lies at the heart of scientific and technological innovation, and yet there are persistent concerns about bias, such as conservatism. This paper investigates the role that the format of evaluation, specifically information... View Details

Keywords: Project Evaluation; Innovation; Knowledge Frontier; Information Sharing; Negativity Bias; Projects; Innovation and Invention; Information; Knowledge Sharing

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March 2021
Article

Increasing the Level of Abstraction as a Strategy for Accelerating the Adoption of Complex Technologies

By: Willy C. Shih

Many new technologies are complex and embody high levels of technical sophistication, and applying them should require significant knowledge and experience. Yet, the rapid adoption and incorporation of these technologies into other innovations seems inconsistent with... View Details

Keywords: Abstraction; Technological And Scientific Innovation; Technological Progress; Diffusion Of Innovation; Technology Adoption; Technological Innovation; Complexity; Information Technology; Strategy

July 2013 (Revised November 2021)
Module Note

Exploration vs. Exploitation

By: Willy Shih

This module note introduces James March's concept of exploration and exploitation, and the management challenge of balancing the allocation of resources to the two activities in the firm. The note also touches on the O'Reilly and Tushman paper on the ambidextrous... View Details

29 May 2001
Research & Ideas

Genomics: Can We Start Making Money Now?

Stefan Thomke, assistant professor Jonathan West, and Senior Research Fellow Juan Enriquez-Cabot. On February 12th of this year, this latest scientific revolution was launched in earnest when two research groups published their work to... View Details

Keywords: by Sean Silverthorne

November 2019 (Revised April 2020)
Technical Note

The Life Sciences Revolution: A Technical Primer

By: Gary P. Pisano, William J. Anderson, Amitabh Chandra, Clarissa Ceruti and Stephanie Oestreich

For more than two decades, scientific advances have been driving profound changes in drug discovery and the drug industry itself. This case provides an overview and description of these technical and scientific advances. Written for the nonscientific reader, it may be... View Details

Keywords: Science; Technological Innovation; Technology; Pharmaceutical Industry; Biotechnology Industry

Educators

02 Dec 2015
HBS Seminar

Fabian Waldinger, Associate Professor, University of Warwick, Department of Economics

23 Sep 2024
Video

Bridging Science and Business: The MS/MBA Biotechnology Life Sciences Program

20 Nov 2006
Research & Ideas

Open Source Science: A New Model for Innovation

scientific and technological activities. And the benefit of opening up your problems to outsiders is that in fact you can get novel solutions—quicker solutions than what the firm or R&D lab might develop. It also opens up new domains... View Details

Keywords: by Martha Lagace

November 2001 (Revised September 2004)
Case

Evolution of Treatment, The: The Case of Diabetes

By: Richard M.J. Bohmer, Jeffrey D. Street and Laura Feldman

Scientific knowledge surrounding diabetes mellitus has grown over the last century to include its cause, treatment, and prevention strategies. However, the type and level of care that patients receive is suboptional. This case examines the forces in industry,... View Details

Keywords: Policy; Health Care and Treatment; Innovation and Management; Knowledge Use and Leverage; Management; Management Analysis, Tools, and Techniques; Health Industry

Educators

Research Summary

Research Interests

Faaiza’s research focuses on how organizations learn and innovate under novel/uncertain circumstances. Organizational design, organizational sociology, strategic planning, knowledge management, and self-organizing teams are areas of special interest to Faaiza. View Details

January 2004 (Revised February 2005)
Background Note

A Note on Methodological Fit in Management Field Research

By: Amy C. Edmondson and Stacy McManus

To use in doctoral-level management courses on the design of field research methods. Advocates the importance of fit, or internal consistency, among the different elements of a field research project. Although the scientific method provides an essential framework for... View Details

Keywords: Management; Research

28 Jul 2010
News

Entrepreneurs run with crowdsourcing model

2006
Book

Science Business: The Promise, the Reality, and the Future of Biotech

By: Gary P. Pisano

Why has the biotechnology industry failed to perform up to expectations—despite all its promise? In Science Business, Gary P. Pisano answers this question by providing an incisive critique of the industry. Pisano not only reveals the underlying causes of... View Details

Keywords: Science; Business Ventures; Biotechnology Industry