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      • November 2023 (Revised April 2024)
      • Case

      BiomX: Bringing Phage Back to the Stage

      By: Paul A. Gompers, Elie Ofek, Orna Dan and Emilie Billaud
      In the spring of 2023, and following the favorable results of a trial involving its phage cocktail for treating lung infections among cystic fibrosis (CF) patients, the leadership of BiomX had several critical issues to wrestle with. First, given its precarious... View Details
      Keywords: Working Capital; Financing and Loans; Health Testing and Trials; Product Development; Research and Development; Science-Based Business; Commercialization; Biotechnology Industry; Pharmaceutical Industry
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      Gompers, Paul A., Elie Ofek, Orna Dan, and Emilie Billaud. "BiomX: Bringing Phage Back to the Stage." Harvard Business School Case 524-051, November 2023. (Revised April 2024.)
      • September 2023
      • Case

      FoodCloud: Tackling Food Insecurity and Climate Change in One Bite

      By: Brian Trelstad and Emer Moloney
      In 2013, Aoibheann O’Brien and Iseult Ward founded FoodCloud, a non-profit social enterprise that aimed to address food waste and food insecurity issues. Through its technology platform, Foodiverse, FoodCloud connected surplus food from retailers with community groups... View Details
      Keywords: Nonprofit Organizations; Expansion; Technological Innovation; Environmental Sustainability; Social Issues; Growth and Development Strategy; Green Technology Industry; Agriculture and Agribusiness Industry; Food and Beverage Industry; Republic of Ireland; Europe
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      Trelstad, Brian, and Emer Moloney. "FoodCloud: Tackling Food Insecurity and Climate Change in One Bite." Harvard Business School Case 324-031, September 2023.
      • September 2023 (Revised March 2024)
      • Case

      ReMo Energy: Sizing Up Investors

      By: Jeffrey J. Bussgang and Tom Quinn
      In 2023, executives with ReMo Energy (founded 2020) were deciding which size ammonia plant to build as their first project. Their innovative model produced ammonia—useful for making fertilizer and for energy storage—from renewable energy, and they had received funding... View Details
      Keywords: Factories, Labs, and Plants; Business Startups; Cost vs Benefits; Design; Energy Conservation; Energy Generation; Renewable Energy; Venture Capital; Investment Return; Goods and Commodities; Size; Infrastructure; Risk and Uncertainty; Science-Based Business; Commercialization; Technological Innovation; Chemical Industry; Energy Industry; Green Technology Industry; United States; Boston
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      Bussgang, Jeffrey J., and Tom Quinn. "ReMo Energy: Sizing Up Investors." Harvard Business School Case 824-027, September 2023. (Revised March 2024.)
      • April 2023
      • Article

      The Subjective Expected Utility Approach and a Framework for Defining Project Risk in Terms of Novelty and Feasibility—A Response to Franzoni and Stephan (2023), ‘Uncertainty and Risk-Taking in Science’

      By: Jacqueline N. Lane
      In their Discussion Paper, Franzoni and Stephan (F&S, 2023) discuss the shortcomings of existing peer review models in shaping the funding of risky science. Their discussion offers a conceptual framework for incorporating risk into peer review models of research... View Details
      Keywords: Risk and Uncertainty; Research; Resource Allocation; Perception
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      Lane, Jacqueline N. "The Subjective Expected Utility Approach and a Framework for Defining Project Risk in Terms of Novelty and Feasibility—A Response to Franzoni and Stephan (2023), ‘Uncertainty and Risk-Taking in Science’." Art. 104707. Research Policy 52, no. 3 (April 2023).
      • 2023
      • Working Paper

      The Subjective Expected Utility Approach and a Framework for Defining Project Risk in Terms of Novelty and Feasibility—A Response to Franzoni and Stephan (2023), ‘Uncertainty and Risk-Taking in Science’

      By: Jacqueline N. Lane
      In their Discussion Paper, Franzoni and Stephan (F&S, 2023) discuss the shortcomings of existing peer review models in shaping the funding of risky science. Their discussion offers a conceptual framework for incorporating risk into peer review models of research... View Details
      Keywords: Risk and Uncertainty; Research; Resource Allocation; Perception
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      Lane, Jacqueline N. "The Subjective Expected Utility Approach and a Framework for Defining Project Risk in Terms of Novelty and Feasibility—A Response to Franzoni and Stephan (2023), ‘Uncertainty and Risk-Taking in Science’." Harvard Business School Working Paper, No. 23-037, January 2023.
      • November 2022
      • Case

      Goonj: Growing in the Face of a Pandemic

      By: V. Kasturi Rangan and Priyank Narayan
      Founded by the husband and wife team of Anshu and Meenakshi Gupta in 1999, Goonj had quickly emerged as one of the leading disaster relief and rural development organizations in India. Their main mode of development was through providing a clothing kit to the village... View Details
      Keywords: COVID-19 Pandemic; Management; Family Business; Natural Disasters; Social Issues; Entrepreneurship; Operations; Business and Community Relations; Strategy; India
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      Rangan, V. Kasturi, and Priyank Narayan. "Goonj: Growing in the Face of a Pandemic." Harvard Business School Case 523-051, November 2022.
      • November 22, 2022
      • Article

      Is Novel Research Worth Doing? Evidence from Peer Review at 49 Journals

      By: Misha Teplitskiy, Hao Peng, Andrea Blasco and Karim R. Lakhani
      There are long-standing concerns that peer review, which is foundational to scientific institutions like journals and funding agencies, favors conservative ideas over novel ones. We investigate the association between novelty and the acceptance of manuscripts submitted... View Details
      Keywords: Research; Journals and Magazines
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      Teplitskiy, Misha, Hao Peng, Andrea Blasco, and Karim R. Lakhani. "Is Novel Research Worth Doing? Evidence from Peer Review at 49 Journals." e2118046119. Proceedings of the National Academy of Sciences 119, no. 47 (November 22, 2022).
      • 2022
      • Working Paper

      How Do Investors Value ESG?

      By: Malcolm Baker, Mark Egan and Suproteem K. Sarkar
      Environmental, social, and governance (ESG) objectives have risen to near the top of the agenda for corporate executives and boards, driven in large part by their perceptions of shareholder interest. We quantify the value that shareholders place on ESG using a revealed... View Details
      Keywords: Investment; Investment Portfolio; Corporate Social Responsibility and Impact; Business and Shareholder Relations; Environmental Sustainability; Governance; Financial Services Industry; United States
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      Baker, Malcolm, Mark Egan, and Suproteem K. Sarkar. "How Do Investors Value ESG?" NBER Working Paper Series, No. 30708, December 2022. (Harvard Business School Working Paper, No. 23-028, November 2022.)
      • October 2022
      • Case

      Single.Earth

      By: Rembrand Koning and Emer Moloney
      Estonian greentech company Single.Earth is launching a nature-backed token that is linked to and funds the protection of a specific plot fo land. The first landowners had been onboarded to the company's Digital Twin, a virtual representation of the planet's natural... View Details
      Keywords: Alternative Assets; Business Startups; Entrepreneurship; Climate Change; Environmental Sustainability; Green Technology; Natural Resources; Pollution; Analytics and Data Science; Marketing; Product Marketing; Product Launch; Product Positioning; Markets; Market Timing; Strategy; Green Technology Industry; Estonia
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      Koning, Rembrand, and Emer Moloney. "Single.Earth." Harvard Business School Case 723-388, October 2022.
      • June 2022
      • Case

      PFA Pensions: The Climate Plus Product

      By: Daniel Green, Victoria Ivashina and Alys Ferragamo
      The case explores whether alternative investments play a unique role in achieving low carbon dioxide emissions at the portfolio level. This case is set in April of 2020 and follows Kasper Ahrndt Lorenzen, Chief Investment Officer, and Peter Tind Larsen, Head of... View Details
      Keywords: Carbon Emissions; Carbon Footprint; Alternative Assets; Alternative Investment Vehicles; Pension Fund Investing; Private Equity; Renewable Energy; Investment Portfolio; Corporate Social Responsibility and Impact; Environmental Sustainability; Denmark
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      Green, Daniel, Victoria Ivashina, and Alys Ferragamo. "PFA Pensions: The Climate Plus Product." Harvard Business School Case 222-088, June 2022.
      • November 2021 (Revised May 2022)
      • Case

      QuantumScape's Mission to Revolutionize Energy Storage for a Sustainable Future

      By: William A. Sahlman, Allison M. Ciechanover and Jeff Huizinga
      QuantumScape CEO Jagdeep Singh juggles the many activities required to lead the next-generation battery pioneer. Founded in 2010, QuantumScape’s mission was to develop new “solid-state” car batteries that would improve upon traditional lithium-ion batteries in key... View Details
      Keywords: Batteries; Electric Vehicles; SPACs; Innovation and Management; Technological Innovation; Science-Based Business; Environmental Sustainability; Auto Industry; Energy Industry; California; San Jose
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      Sahlman, William A., Allison M. Ciechanover, and Jeff Huizinga. "QuantumScape's Mission to Revolutionize Energy Storage for a Sustainable Future." Harvard Business School Case 822-044, November 2021. (Revised May 2022.)
      • July 2021
      • Article

      Material Sustainability Information and Stock Price Informativeness

      By: Jody Grewal, Clarissa Hauptmann and George Serafeim
      As part of the SEC’s revision of Regulation S-K, many investors proposed the mandatory disclosure of sustainability information in the form of environmental, social, and governance (ESG) data. However, progress is contingent on collecting evidence regarding which... View Details
      Keywords: Voluntary Disclosure; Accounting Standards; Sustainability; Nonfinancial Information; Corporate Social Responsibility; Stock Price Informativeness; Synchronicity; Environmental Sustainability; Corporate Disclosure; Corporate Accountability; Stocks; Price; Corporate Social Responsibility and Impact; Accounting; Standards
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      Grewal, Jody, Clarissa Hauptmann, and George Serafeim. "Material Sustainability Information and Stock Price Informativeness." Journal of Business Ethics 171, no. 3 (July 2021): 513–544.
      • 2021
      • Working Paper

      Studying the U.S.-Based Portfolio Companies of U.S. Impact Investors

      By: M. Diane Burton, Gurveen Chadha, Shawn A. Cole, Abhishek Dev, Christina Jarymowycz, Leslie Jeng, Laura Kelley, Josh Lerner, Jaime R. Diaz Palacios, Yue (Cynthia) Xu and T. Robert Zochowski
      Recent years have seen a dramatic increase in the reliance on market-based solutions to social and environmental problems around the world (Barman 2016; Horvath and Powell 2020). The growth of impact investing is a vivid example of this trend and, although there have... View Details
      Keywords: Impact Investing; Impact Portfolio Companies; Investment; Social Issues; Environmental Sustainability; Investment Portfolio; Business Ventures; Analytics and Data Science; Performance; United States
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      Burton, M. Diane, Gurveen Chadha, Shawn A. Cole, Abhishek Dev, Christina Jarymowycz, Leslie Jeng, Laura Kelley, Josh Lerner, Jaime R. Diaz Palacios, Yue (Cynthia) Xu, and T. Robert Zochowski. "Studying the U.S.-Based Portfolio Companies of U.S. Impact Investors." Harvard Business School Working Paper, No. 21-130, June 2021.
      • April 2021 (Revised July 2021)
      • Case

      Public Equities Impact Investing at BlackRock

      By: Shawn A. Cole, Vikram S. Gandhi, Michael Norris and John Masko
      In early 2021, BlackRock—the world’s largest asset manager with $9 trillion in assets under management (AUM)—sought to become a leader in promoting environmental and social sustainability. Over the previous ten years, CEO Larry Fink had written an annual open letter to... View Details
      Keywords: Impact Investing; Renewable Energy; Climate Change; Environmental Sustainability; Equity; Corporate Social Responsibility and Impact; Financial Management; Investment Funds; Investment Return; Mission and Purpose; Organizational Change and Adaptation; Financial Services Industry; United States
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      Cole, Shawn A., Vikram S. Gandhi, Michael Norris, and John Masko. "Public Equities Impact Investing at BlackRock." Harvard Business School Case 221-066, April 2021. (Revised July 2021.)
      • January 2021
      • Supplement

      Bespoken Spirits: Disrupting Distilling

      By: Benjamin C. Esty and Daniel Fisher
      On October 7, 2020, Bespoken Spirits publicly announced it had received $2.6 million of seed funding for its “sustainable maturation process,” a process that could produce award-winning whiskeys in just days rather than years using a novel technology and data science. ... View Details
      Keywords: Business Ventures; Business Strategy; Competitive Advantage; Disruption; Entrepreneurship; Environmental Sustainability; Cash Flow; Disruptive Innovation; Innovation Strategy; Brands and Branding; Business Model; Consumer Products Industry; Food and Beverage Industry; Service Industry; United States; California
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      Esty, Benjamin C., and Daniel Fisher. "Bespoken Spirits: Disrupting Distilling." Harvard Business School Spreadsheet Supplement 721-852, January 2021.
      • January 2021
      • Case

      Bespoken Spirits: Disrupting Distilling

      By: Benjamin C. Esty and Daniel Fisher
      On October 7, 2020, Bespoken Spirits publicly announced it had received $2.6 million of seed funding for its “sustainable maturation process,” a process that could produce award-winning whiskeys in just days rather than years using a novel technology and data science. ... View Details
      Keywords: Business Ventures; Business Strategy; Competitive Advantage; Disruption; Entrepreneurship; Environmental Sustainability; Cash Flow; Disruptive Innovation; Innovation Strategy; Brands and Branding; Business Model; Consumer Products Industry; Food and Beverage Industry; Service Industry; United States; California
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      Esty, Benjamin C., and Daniel Fisher. "Bespoken Spirits: Disrupting Distilling." Harvard Business School Case 721-419, January 2021.
      • October 2020 (Revised November 2020)
      • Case

      Wilderness Safaris: Impact Investing and Ecotourism Conservation in Africa

      By: James E. Austin, Megan Epler Wood and Herman B. "Dutch" Leonard
      In 2018 the majority ownership of publicly owned Wilderness Safaris, the leading high-end ecotourism company in Africa with safari operations in eight countries, was acquired by The Rise Fund, one of the world’s largest private social impact investing funds, and by FS... View Details
      Keywords: Investing; Investing For Impact; Ecotourism; COVID-19; Equity Financing; Strategy Formulation; Profitability; Environmental And Social Sustainability; Sustainability; Conservation Planning; Corporate Social Responsibility; Investment; Social Enterprise; Social Entrepreneurship; Environmental Sustainability; Strategy; Financing and Loans; Corporate Social Responsibility and Impact; Health Pandemics; Tourism Industry; Africa; Rwanda; Angola
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      Austin, James E., Megan Epler Wood, and Herman B. "Dutch" Leonard. "Wilderness Safaris: Impact Investing and Ecotourism Conservation in Africa." Harvard Business School Case 321-020, October 2020. (Revised November 2020.)
      • October 2020
      • Article

      The Elasticity of Science

      By: Kyle Myers
      This paper identifies the degree to which scientists are willing to change the direction of their work in exchange for resources. Data from the National Institutes of Health are used to estimate how scientists respond to targeted funding opportunities. Inducing a... View Details
      Keywords: Scientists; Funding; Research; Change
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      Myers, Kyle. "The Elasticity of Science." American Economic Journal: Applied Economics 12, no. 4 (October 2020): 103–134.
      • June 2020
      • Teaching Note

      Generation Investment Management

      By: Vikram S. Gandhi and Sarah Mehta
      This teaching note provides guidance for teaching the case “Generation Investment Management” (820-033), which looks at the challenges facing a sustainable investment firm. View Details
      Keywords: Sustainable Investing; Socially Responsible Investing; Long-term Investing; ESG; Climate Change; Environmental Sustainability; Finance; Equity; Governance; Private Equity; Public Equity; Financial Markets; Investment; Investment Return; Investment Activism; Investment Funds; Investment Portfolio; Institutional Investing; Corporate Social Responsibility and Impact; Financial Services Industry; United Kingdom; England; London
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      Gandhi, Vikram S., and Sarah Mehta. "Generation Investment Management." Harvard Business School Teaching Note 820-112, June 2020.
      • 2020
      • Working Paper

      Scientific Production: An Exploration into Organization, Resource Allocation, and Funding

      By: Jerry Thursby, Marie Thursby, Karim R. Lakhani, Kyle R. Myers, Nina Cohodes, Sarah Bratt, Dennis Byrski, Hannah Cohoon and Maria Roche
      Production of scientific knowledge is core to civilizational advancement in economic and material wellbeing of societies. Despite its fundamental importance, however, a systematic effort to quantitatively study the factors underlying scientific production, particularly... View Details
      Keywords: Funding; Science; Knowledge; Research; Information Management; Resource Allocation
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      Thursby, Jerry, Marie Thursby, Karim R. Lakhani, Kyle R. Myers, Nina Cohodes, Sarah Bratt, Dennis Byrski, Hannah Cohoon, and Maria Roche. "Scientific Production: An Exploration into Organization, Resource Allocation, and Funding." Working Paper, May 2020.
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